Takepron combined with Tocilizumab

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Cardiac Failure Life Threatening 1/20/2009 Female 77 lb 2/11/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Cardiac Failure Life Threatening 1/20/2009 Female 77 lb 3/6/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 12/11/2008 Female 77 lb 4/9/2009 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Life Threatening 1/20/2009 Female 77 lb 4/16/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 7/4/2008 Female 77 lb 1/18/2010 Physician Japan
Primary
Secondary
Concomitant
Rash Generalised Life Threatening 7/30/2008 Male 108 lb 1/20/2010 Physician Japan
Primary
Secondary
Concomitant
Cerebral Haemorrhage Other Serious 11/16/2009 Female 1/21/2010 Physician Japan
Primary
Concomitant
Pancreatic Carcinoma Death 9/10/2009 Female 106 lb 1/21/2010 Physician Japan
Primary
Concomitant
Hypertriglyceridaemia Other Serious 9/3/2009 Male 137 lb 1/22/2010 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 11/27/2007 Male 146 lb 2/1/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/21/2009 Female 2/1/2010 Physician Japan
Primary
Concomitant
Gastroenteritis Hospitalization 8/28/2009 Female 106 lb 2/2/2010 Physician Japan
Primary
Secondary
Concomitant
Lymphoma Hospitalization 9/22/2009 Female 99 lb 2/9/2010 Physician Japan
Primary
Secondary
Concomitant
Septic Shock Hospitalization 12/9/2008 Male 2/12/2010 Physician Japan
Primary
Secondary
Concomitant
Rash Generalised Life Threatening 7/30/2008 Male 108 lb 2/16/2010 Physician Japan
Primary
Secondary
Concomitant
Subcutaneous Abscess Other Serious 10/16/2009 Female 2/25/2010 Other Health Professional Japan
Primary
Concomitant
Sepsis Other Serious 2/15/2009 Male 165 lb 2/26/2010 Physician Japan
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 10/2/2008 28 Female 112 lb 3/4/2010 Physician Japan
Primary
Secondary
Concomitant
Pancreatic Carcinoma Life Threatening 8/7/2009 Female 106 lb 3/4/2010 Physician Japan
Primary
Concomitant
Gastroenteritis Hospitalization 8/28/2009 Female 106 lb 3/5/2010 Physician Japan
Primary
Secondary
Concomitant
Colitis Ulcerative Other Serious 12/16/2008 Male 126 lb 3/10/2010 Physician Japan
Primary
Concomitant
Gastric Perforation Life Threatening 5/14/2009 Female 95 lb 3/11/2010 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 11/27/2007 Male 146 lb 3/15/2010 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 9/17/2009 57 Male 108 lb 4/12/2010 Physician Japan
Primary
Concomitant
Ulnar Neuritis Other Serious 7/7/2009 40 Male 203 lb 4/14/2010 Physician Japan
Primary
Secondary
Concomitant
Lower Gastrointestinal Haemorrhage Hospitalization Female 143 lb 4/21/2010 Physician Japan
Primary
Concomitant
Oral Herpes Other Serious 8/13/2008 66 Female 143 lb 4/22/2010 Physician Japan
Primary
Concomitant
Respiratory Failure Hospitalization 10/7/2009 65 Male 4/27/2010 Physician Japan
Primary
Secondary
Concomitant
Lower Gastrointestinal Haemorrhage Hospitalization Female 143 lb 4/27/2010 Physician Japan
Primary
Concomitant
Death Neonatal Other Serious 32 4/28/2010 Physician Japan
Primary
Secondary
Concomitant
Gastroenteritis Hospitalization 8/28/2009 72 Female 106 lb 5/12/2010 Physician Japan
Primary
Secondary
Concomitant
Sinusitis Hospitalization 8/24/2009 68 Female 5/15/2010 Physician Japan
Primary
Concomitant
Bladder Cancer Hospitalization 7/30/2009 83 Male 110 lb 5/17/2010 Physician Japan
Primary
Secondary
Concomitant
Pyelonephritis Hospitalization 4/27/2010 76 Female 119 lb 5/18/2010 Physician Japan
Primary
Concomitant
Oral Herpes Other Serious 8/13/2008 66 Female 143 lb 5/20/2010 Physician Japan
Primary
Secondary
Concomitant
Hypercholesterolaemia Other Serious 11/10/2009 56 Female 5/27/2010 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Death 5/6/2009 68 Male 123 lb 5/28/2010 Physician Japan
Primary
Concomitant
Lip And/or Oral Cavity Cancer Hospitalization 9/1/2009 66 Female 6/2/2010 Physician Japan
Primary
Concomitant
Vision Blurred Hospitalization 8/11/2009 62 Female 110 lb 6/8/2010 Physician Japan
Primary
Concomitant
Oral Herpes Other Serious 8/13/2008 66 Female 143 lb 6/9/2010 Physician Japan
Primary
Secondary
Concomitant
Sepsis Hospitalization 4/1/2009 61 Female 6/14/2010 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Death 5/6/2009 68 Male 123 lb 6/15/2010 Physician Japan
Primary
Concomitant
Hyperglycaemia Other Serious 9/18/2009 81 Female 6/17/2010 Physician Japan
Primary
Concomitant
Neonatal Asphyxia Other Serious 11/27/2009 Female 6 lb 6/22/2010 Physician Japan
Primary
Secondary
Concomitant
Hypertriglyceridaemia Hospitalization 1/12/2010 60 Female 115 lb 6/22/2010 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 9/17/2009 57 Male 108 lb 6/30/2010 Physician Japan
Primary
Concomitant
Ulnar Neuritis Other Serious 7/7/2009 40 Male 236 lb 7/9/2010 Physician Japan
Primary
Secondary
Concomitant
Lymphopenia Other Serious 6/1/2009 71 Male 139 lb 7/9/2010 Physician Japan
Primary
Concomitant
Wound Infection Hospitalization 11/22/2008 58 Male 132 lb 7/9/2010 Physician Japan
Primary
Secondary
Concomitant
Breast Cancer Hospitalization 3/4/2010 63 Female 7/16/2010 Physician Japan
Primary
Concomitant
Ileus Hospitalization 10/26/2009 59 Female 110 lb 7/16/2010 Physician Japan
Primary
Concomitant
Pancytopenia Other Serious Male 90 lb 7/19/2010 Physician Japan
Primary
Concomitant
Lung Neoplasm Malignant Hospitalization Female 7/19/2010 Physician Japan
Primary
Concomitant
Spinal Compression Fracture Hospitalization 8/13/2009 61 Female 7/22/2010 Physician Japan
Primary
Secondary
Concomitant
Retinal Detachment Hospitalization 12/28/2009 55 Male 118 lb 7/23/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 7/29/2008 4 Male 54 lb 7/29/2010 Other Health Professional Japan
Primary
Concomitant
Cerebral Infarction Hospitalization 4/2/2010 70 Female 134 lb 7/29/2010 Physician Japan
Primary
Concomitant
Hepatic Steatosis Other Serious 12/28/2009 61 Female 7/30/2010 Physician Japan
Primary
Concomitant
Histiocytosis Haematophagic Other Serious 8/20/2009 36 Female 8/2/2010 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 8/27/2009 78 Female 117 lb 8/5/2010 Physician Japan
Primary
Secondary
Concomitant
Sciatica Life Threatening 1/1/2008 68 Female 8/6/2010 Physician Japan
Primary
Concomitant
Sialoadenitis Other Serious 9/3/2009 60 Male 137 lb 8/10/2010 Physician Japan
Primary
Secondary
Concomitant
Pyelonephritis Hospitalization 4/27/2010 76 Female 119 lb 8/16/2010 Physician Japan
Primary
Concomitant
Neonatal Asphyxia Death 11/27/2009 Female 6 lb 8/17/2010 Physician Japan
Primary
Secondary
Concomitant
Upper Respiratory Tract Inflammation Hospitalization 9/2/2008 47 Male 8/17/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Pleural Effusion Life Threatening 8/16/2010 64 Female 130 lb 8/20/2010 Physician Japan
Primary
Secondary
Concomitant
Spinal Compression Fracture Hospitalization 8/13/2009 61 Female 8/23/2010 Physician Japan
Primary
Secondary
Concomitant
Hypertriglyceridaemia Hospitalization 11/17/2009 60 Female 115 lb 8/23/2010 Physician Japan
Primary
Concomitant
Sciatica Life Threatening 3/19/2010 70 Female 86 lb 8/23/2010 Physician Japan
Primary
Concomitant
Pleural Effusion Life Threatening 8/16/2010 64 Female 130 lb 8/23/2010 Physician Japan
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 9/18/2008 31 Female 8/27/2010 Physician Japan
Primary
Secondary
Concomitant
Upper Respiratory Tract Inflammation Hospitalization 9/2/2008 47 Male 8/27/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Gastroenteritis Hospitalization 8/28/2009 72 Female 106 lb 9/10/2010 Physician Japan
Primary
Secondary
Concomitant
Breast Cancer Hospitalization 3/4/2010 63 Female 9/15/2010 Physician Japan
Primary
Concomitant
Hodgkin's Disease Stage Iv Other Serious 8/31/2009 73 Female 157 lb 9/21/2010 Physician Japan
Primary
Secondary
Concomitant
Shock Death 4/27/2009 58 Female 9/21/2010 Physician Japan
Primary
Secondary
Concomitant
Histiocytosis Haematophagic Other Serious 8/20/2009 36 Female 9/23/2010 Physician Japan
Primary
Concomitant
Glomerulonephritis Acute Other Serious 3/16/2010 61 Female 126 lb 9/23/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 8/11/2009 58 Female 9/24/2010 Physician Japan
Primary
Secondary
Concomitant
Pancytopenia 11/29/2009 69 Male 90 lb 9/27/2010 Physician Japan
Primary
Concomitant
Peritonitis Life Threatening 8/16/2010 64 Female 130 lb 9/27/2010 Physician Japan
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 9/18/2008 31 Female 9/27/2010 Physician Japan
Primary
Secondary
Concomitant
Hypertriglyceridaemia Other Serious 9/3/2009 60 Male 137 lb 10/1/2010 Physician Japan
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 8/11/2009 62 Female 110 lb 10/4/2010 Physician Japan
Primary
Secondary
Concomitant
Nausea Hospitalization 3/30/2009 66 Female 121 lb 10/5/2010 Physician Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 1/29/2009 28 Female 117 lb 10/5/2010 Physician Japan
Primary
Secondary
Concomitant
Wound Infection Hospitalization 11/22/2008 58 Male 132 lb 10/5/2010 Physician Japan
Primary
Secondary
Concomitant
Retinal Detachment Hospitalization 10/13/2009 55 Male 118 lb 10/5/2010 Physician Japan
Primary
Concomitant
Renal Failure Hospitalization 10/15/2009 75 Male 110 lb 10/6/2010 Physician Japan
Primary
Concomitant
Rheumatoid Arthritis Other Serious 9/18/2008 31 Female 10/6/2010 Physician Japan
Primary
Secondary
Concomitant
Hypertriglyceridaemia Other Serious 9/3/2009 60 Male 137 lb 10/6/2010 Physician Japan
Primary
Secondary
Concomitant
Ileus Hospitalization 10/26/2009 59 Female 110 lb 10/7/2010 Physician Japan
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 8/27/2009 78 Female 117 lb 10/7/2010 Physician Japan
Primary
Secondary
Concomitant
Colitis Ulcerative Other Serious 12/16/2008 64 Male 126 lb 10/13/2010 Physician Japan
Primary
Concomitant
Lip And/or Oral Cavity Cancer Hospitalization 9/1/2009 66 Female 10/13/2010 Physician Japan
Primary
Concomitant
Rash Generalised Life Threatening 7/30/2008 56 Male 108 lb 10/18/2010 Physician Japan
Primary
Secondary
Concomitant
Peripheral Vascular Disorder Life Threatening 3/19/2010 70 Female 86 lb 10/19/2010 Physician Japan
Primary
Concomitant
Hypertriglyceridaemia Other Serious 9/3/2009 60 Male 137 lb 10/25/2010 Physician Japan
Primary
Secondary
Concomitant
Lip And/or Oral Cavity Cancer Hospitalization 8/27/2009 66 Female 10/27/2010 Physician Japan
Primary
Concomitant
Tachycardia Other Serious 3/1/2010 70 Female 86 lb 11/1/2010 Physician Japan
Primary
Secondary
Concomitant
Histiocytosis Haematophagic Other Serious 8/20/2009 36 Female 11/2/2010 Physician Japan
Primary
Concomitant
Sporotrichosis Hospitalization 9/1/2008 78 Male 112 lb 11/5/2010 Physician Japan
Primary
Concomitant
Rheumatoid Arthritis Other Serious 9/18/2008 31 Female 11/9/2010 Physician Japan
Primary
Secondary
Concomitant
Hodgkin's Disease Stage Iv Other Serious 8/31/2009 73 Female 157 lb 11/9/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Hospitalization 10/13/2009 75 Male 110 lb 11/12/2010 Physician Japan
Primary
Concomitant
Renal Disorder Hospitalization 3/1/2010 61 Female 134 lb 11/15/2010 Physician Japan
Primary
Concomitant
Tachycardia Other Serious 3/1/2010 70 Female 86 lb 11/17/2010 Physician Japan
Primary
Secondary
Concomitant
Tachycardia Other Serious 3/1/2010 70 Female 86 lb 11/18/2010 Physician Japan
Primary
Secondary
Concomitant
Tachycardia Other Serious 3/1/2010 70 Female 86 lb 12/6/2010 Physician Japan
Primary
Secondary
Concomitant
Hydronephrosis Other Serious 9/27/2010 73 Female 110 lb 12/9/2010 Physician Japan
Primary
Concomitant
Palpitations Other Serious 5/1/2010 42 Female 154 lb 12/17/2010 Other Health Professional Japan
Primary
Concomitant
Lymphopenia Hospitalization 2/4/2009 71 Male 137 lb 12/28/2010 Physician Japan
Primary
Concomitant
Gastric Cancer Death 9/27/2010 73 Female 110 lb 1/3/2011 Other Health Professional Japan
Primary
Concomitant
Melaena Hospitalization 7/15/2009 49 Female 165 lb 1/19/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Joint Arthroplasty Hospitalization 9/22/2008 30 Female 88 lb 1/31/2011 Physician Japan
Primary
Concomitant
Cytomegalovirus Infection Hospitalization 3/3/2010 61 Female 134 lb 1/31/2011 Other Health Professional Japan
Primary
Concomitant
Tendon Rupture Hospitalization 3/31/2009 83 Female 110 lb 2/3/2011 Physician Japan
Primary
Secondary
Concomitant
Melaena Hospitalization 7/15/2009 49 Female 165 lb 2/14/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Death 3/20/2010 73 Female 2/23/2011 Physician Japan
Primary
Concomitant
Non-hodgkin's Lymphoma Hospitalization 9/22/2009 62 Female 99 lb 2/23/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Aspiration Other Serious 3/20/2010 73 Female 3/3/2011 Other Health Professional Japan
Primary
Concomitant
Melaena Hospitalization 7/15/2009 49 Female 165 lb 3/7/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Liver Disorder 3/29/2010 62 Female 110 lb 3/8/2011 Physician Japan
Primary
Concomitant
Enteritis Infectious Hospitalization 10/13/2009 75 Male 110 lb 3/8/2011 Physician Japan
Primary
Concomitant
Capillary Permeability Increased Death 3/20/2010 73 Female 3/9/2011 Other Health Professional Japan
Primary
Concomitant
Hyponatraemia Hospitalization 2/24/2011 67 Female 3/14/2011 Other Health Professional Japan
Primary
Concomitant
Cellulitis Hospitalization 3/7/2009 71 Male 112 lb 3/15/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 2/24/2011 67 Female 3/16/2011 Physician Japan
Primary
Concomitant
Diabetes Mellitus Other Serious 9/3/2009 60 Male 137 lb 3/23/2011 Physician Japan
Primary
Secondary
Concomitant
Hydrocephalus Hospitalization 2/24/2011 67 Female 3/28/2011 Other Health Professional Japan
Primary
Concomitant
Gastric Cancer Death 9/27/2010 73 Female 110 lb 4/13/2011 Physician Japan
Primary
Concomitant
Meningitis Cryptococcal Hospitalization 2/24/2011 67 Female 4/19/2011 Physician Japan
Primary
Concomitant
Blood Urea Increased Death 6/12/2009 70 Male 4/20/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Pneumonia Aspiration Death 3/20/2010 73 Female 4/22/2011 Physician Japan
Primary
Concomitant
Cellulitis Hospitalization 3/7/2009 71 Male 112 lb 4/28/2011 Physician Japan
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 2/24/2011 67 Female 4/28/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Neonatal Asphyxia Death 11/27/2009 Female 6 lb 4/29/2011 Physician Japan
Primary
Secondary
Concomitant
Osteoporosis Hospitalization 12/22/2009 10 Male 10/26/2012 Physician Jp
Primary
Secondary
Concomitant
Sinusitis Hospitalization 8/24/2009 68 Female 3/6/2013 Physician Jp
Primary
Concomitant
Upper Respiratory Tract Inflammation Hospitalization 9/2/2008 47 Male 2/4/2013 Country Not Specified
Primary
Secondary
Concomitant
Upper Respiratory Tract Inflammation Other Serious 1/29/2009 28 Female 117 lb 1/3/2013 Physician Country Not Specified
Primary
Secondary
Concomitant
Spinal Compression Fracture Hospitalization 3/5/2009 65 Male 121 lb 3/14/2013 Physician Jp
Primary
Secondary
Concomitant
Atypical Pneumonia Hospitalization 3/8/2012 55 Male 3/6/2013 Physician Jp
Primary
Secondary
Concomitant
Uterine Dilation And Evacuation Other Serious 3/8/2010 34 Female 11/23/2012 Physician Jp
Primary
Secondary
Concomitant
Foetal Death Death 3/8/2010 11/23/2012 Physician Jp
Primary
Secondary
Concomitant
Swelling Face Hospitalization 2012 Female 132 lb 9/28/2012 Consumer Country Not Specified
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Life Threatening 7/25/2010 71 Female 86 lb 10/30/2012 Consumer Country Not Specified
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 7/9/2012 73 Female 110 lb 12/21/2012 Physician Jp
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/11/2012 68 Female 108 lb 12/20/2012 Physician Jp
Primary
Concomitant
Interacting
Rash Hospitalization 12/14/2012 62 Male 12/14/2012 Jp
Primary
Secondary
Concomitant

Drug Data