Blinded Tocilizumab combined with Tocilizumab

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Hospitalization 7/28/2006 64 Female 157 lb 8/18/2006 Physician Canada
Primary
Secondary
Concomitant
Thalamic Infarction Hospitalization 11/29/2005 53 Female 159 lb 9/15/2006 Physician Japan
Primary
Secondary
Concomitant
Non-hodgkin's Lymphoma Hospitalization 5/7/2009 Male 274 lb 6/18/2009 Physician United States
Primary
Secondary
Concomitant
Non-hodgkin's Lymphoma Hospitalization 5/7/2009 Male 274 lb 8/7/2009 Physician United States
Primary
Secondary
Concomitant
Osteomyelitis Hospitalization 12/15/2009 Female 158 lb 1/14/2010 Physician United States
Primary
Secondary
Concomitant
Tremor Hospitalization 10/1/2009 Female 176 lb 1/15/2010 Physician Bulgaria
Primary
Secondary
Concomitant
Tremor Hospitalization 10/1/2009 Female 176 lb 1/18/2010 Physician Bulgaria
Primary
Secondary
Concomitant
Subdural Haematoma Hospitalization 12/6/2009 Female 117 lb 1/25/2010 Physician Mexico
Primary
Secondary
Concomitant
Bladder Cancer Other Serious 12/3/2009 Male 176 lb 1/27/2010 Physician Italy
Primary
Secondary
Concomitant
Subdural Haematoma Hospitalization 12/6/2009 Female 117 lb 1/29/2010 Physician Mexico
Primary
Secondary
Concomitant
Tremor Hospitalization 10/1/2009 Female 176 lb 2/1/2010 Physician Bulgaria
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/21/2009 Female 481 lb 2/8/2010 Physician United States
Primary
Secondary
Concomitant
Tremor Hospitalization 10/1/2009 Female 176 lb 2/17/2010 Physician Bulgaria
Primary
Secondary
Concomitant
Fasciitis Hospitalization 4/18/2007 Male 208 lb 2/18/2010 Physician Canada
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 1/5/2010 Female 194 lb 3/2/2010 Physician United States
Primary
Secondary
Concomitant
Gallbladder Perforation Hospitalization 9/21/2009 Female 172 lb 3/4/2010 Physician United States
Primary
Secondary
Concomitant
Vaginal Haemorrhage Hospitalization 9/10/2006 Female 118 lb 3/10/2010 Physician Mexico
Primary
Secondary
Concomitant
Pseudomonas Infection Life Threatening 9/10/2006 Female 118 lb 3/11/2010 Physician Mexico
Primary
Secondary
Concomitant
Subdural Haematoma Life Threatening 12/6/2009 Female 118 lb 3/11/2010 Physician Mexico
Primary
Secondary
Concomitant
Breast Cancer Other Serious 12/24/2009 Female 174 lb 3/18/2010 Physician Israel
Primary
Secondary
Diverticular Perforation Hospitalization 6/20/2008 Female 212 lb 3/25/2010 Physician Mexico
Primary
Secondary
Concomitant
Death Death 3/12/2010 Female 192 lb 3/26/2010 Physician United States
Primary
Secondary
Concomitant
Venous Injury Life Threatening 12/6/2009 Female 118 lb 3/26/2010 Physician Mexico
Primary
Secondary
Concomitant
Pseudomonas Infection Life Threatening 9/10/2006 Female 118 lb 3/29/2010 Physician Mexico
Primary
Secondary
Concomitant
Deep Vein Thrombosis Life Threatening 9/21/2009 Female 172 lb 3/29/2010 Physician United States
Primary
Secondary
Concomitant
Death Death 3/12/2010 Female 192 lb 3/29/2010 Physician United States
Primary
Secondary
Concomitant
Cellulitis Staphylococcal Hospitalization 4/18/2007 Male 208 lb 3/31/2010 Physician Canada
Primary
Secondary
Concomitant
Breast Cancer Female Other Serious 12/24/2009 Female 174 lb 3/31/2010 Physician Israel
Primary
Secondary
Concomitant
Renal Disorder Other Serious 2/15/2010 72 Female 225 lb 4/1/2010 Physician Australia
Primary
Secondary
Concomitant
Cardiac Arrest Death 3/12/2010 73 Female 192 lb 4/1/2010 Physician United States
Primary
Secondary
Concomitant
Transitional Cell Carcinoma Hospitalization 12/3/2009 71 Male 176 lb 4/2/2010 Physician Italy
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Life Threatening 3/29/2010 52 Male 137 lb 4/5/2010 Physician China
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/21/2009 69 Female 481 lb 4/6/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization Female 4/13/2010 Consumer Poland
Primary
Secondary
Breast Cancer Hospitalization 1/27/2010 61 Female 174 lb 4/14/2010 Physician Israel
Primary
Secondary
Concomitant
Diverticular Perforation Hospitalization 6/20/2008 54 Female 212 lb 4/16/2010 Physician Mexico
Primary
Secondary
Concomitant
Constipation Hospitalization 4/4/2010 78 Female 127 lb 4/16/2010 Physician United States
Primary
Secondary
Urinary Tract Infection Hospitalization 4/3/2010 71 Male 149 lb 4/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 4/3/2010 71 Male 149 lb 4/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tendon Rupture Other Serious 1/25/2010 49 Female 4/21/2010 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/21/2009 69 Female 481 lb 4/28/2010 Physician United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 4/3/2010 71 Male 149 lb 4/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Rectal Cancer Life Threatening 1/7/2010 65 Female 220 lb 5/3/2010 Physician France
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 3/1/2010 40 Female 5/4/2010 Consumer Poland
Primary
Secondary
Renal Failure Acute Life Threatening 11/9/2009 61 Female 116 lb 5/13/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 11/9/2009 61 Female 116 lb 5/14/2010 Physician United States
Primary
Secondary
Concomitant
Rectal Cancer Stage I Life Threatening 1/7/2010 65 Female 220 lb 5/14/2010 Physician France
Primary
Secondary
Concomitant
Pulmonary Veno-occlusive Disease Life Threatening 11/23/2009 16 Female 121 lb 5/25/2010 Physician Italy
Primary
Secondary
Concomitant
Rectal Cancer Stage I Life Threatening 1/7/2010 65 Female 220 lb 5/28/2010 Physician France
Primary
Secondary
Concomitant
Prostate Cancer Other Serious 5/4/2010 71 Male 6/3/2010 Physician Italy
Primary
Secondary
Concomitant
Pulmonary Veno-occlusive Disease Life Threatening 11/23/2009 16 Female 121 lb 6/8/2010 Physician Italy
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 4/3/2010 71 Male 152 lb 6/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Lymphadenitis Hospitalization 6/10/2010 44 Female 123 lb 6/17/2010 Physician United States
Primary
Secondary
Concomitant
Prostate Cancer Other Serious 1/7/2010 71 Male 176 lb 6/18/2010 Physician Italy
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 4/3/2010 71 Male 152 lb 6/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Non-small Cell Lung Cancer Metastatic Hospitalization 6/4/2009 64 Female 172 lb 6/29/2010 Physician Canada
Primary
Secondary
Concomitant
Nephrolithiasis Hospitalization 6/20/2010 49 Male 198 lb 6/29/2010 Physician Lithuania
Primary
Secondary
Concomitant
Rectal Cancer Life Threatening 1/7/2010 65 Female 220 lb 6/28/2010 Physician France
Primary
Secondary
Concomitant
Subdural Haematoma Hospitalization 6/18/2010 69 Female 218 lb 7/9/2010 Physician Canada
Primary
Secondary
Concomitant
Nephrolithiasis Hospitalization 6/20/2010 49 Male 198 lb 7/15/2010 Physician Lithuania
Primary
Secondary
Concomitant
Abortion Induced Other Serious 7/1/2010 27 Female 7/15/2010 Physician Puerto Rico
Primary
Secondary
Nervous System Disorder Hospitalization 7/4/2010 70 Female 7/21/2010 Physician United States
Primary
Secondary
Nervous System Disorder Hospitalization 7/4/2010 70 Female 7/22/2010 Physician United States
Primary
Secondary
Acute Febrile Neutrophilic Dermatosis Other Serious 6/3/2006 58 Female 134 lb 7/23/2010 Physician Mexico
Primary
Secondary
Concomitant
Intestinal Perforation Other Serious 7/17/2010 61 Female 161 lb 7/29/2010 Physician Mexico
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 7/4/2010 70 Female 7/30/2010 Physician United States
Primary
Secondary
Intestinal Perforation Other Serious 7/17/2010 61 Female 161 lb 8/3/2010 Physician Mexico
Primary
Secondary
Concomitant
Intestinal Perforation Other Serious 7/17/2010 61 Female 161 lb 8/13/2010 Physician Mexico
Primary
Secondary
Concomitant
Cerebral Infarction Other Serious 7/4/2010 70 Female 140 lb 8/18/2010 Physician United States
Primary
Secondary
Concomitant
Panniculitis Disability 12/13/2009 17 Female 110 lb 8/26/2010 Physician Italy
Primary
Secondary
Concomitant
Nephrolithiasis Hospitalization 6/20/2010 49 Male 198 lb 9/2/2010 Physician Lithuania
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 7/19/2010 63 Female 150 lb 9/3/2010 Physician Poland
Primary
Secondary
Concomitant
Chest Pain Hospitalization 8/25/2010 48 Female 130 lb 9/9/2010 Physician South Africa
Primary
Secondary
Concomitant
Pulmonary Veno-occlusive Disease Life Threatening 11/23/2009 16 Female 121 lb 9/17/2010 Physician Italy
Primary
Secondary
Concomitant
Pelvic Fracture Hospitalization 7/30/2010 62 Female 9/24/2010 Physician Japan
Primary
Secondary
Concomitant
Cerebral Infarction Other Serious 7/4/2010 70 Female 140 lb 10/1/2010 Physician United States
Primary
Secondary
Concomitant
Leukocytoclastic Vasculitis Other Serious 2/12/2007 53 Female 188 lb 10/1/2010 Physician Argentina
Primary
Secondary
Concomitant
Skin Papilloma Hospitalization 2/1/2010 78 Female 179 lb 10/6/2010 Physician Hungary
Primary
Secondary
Concomitant
Prostate Cancer Hospitalization 6/23/2010 74 Male 10/8/2010 Physician Germany
Primary
Secondary
Concomitant
Large Intestinal Ulcer Other Serious 7/17/2010 61 Female 161 lb 10/15/2010 Physician Mexico
Primary
Secondary
Concomitant
Leukocytoclastic Vasculitis Other Serious 2/12/2007 53 Female 188 lb 10/15/2010 Physician Argentina
Primary
Secondary
Concomitant
Lymphadenitis Hospitalization 6/10/2010 44 Female 123 lb 10/19/2010 Physician United States
Primary
Secondary
Concomitant
Leukocytoclastic Vasculitis Other Serious 2/12/2007 53 Female 188 lb 10/21/2010 Physician Argentina
Primary
Secondary
Concomitant
Pelvic Fracture Hospitalization 7/30/2010 62 Female 10/22/2010 Physician Japan
Primary
Secondary
Concomitant
Gastric Ulcer Hospitalization 10/11/2010 56 Female 10/28/2010 Physician Japan
Primary
Concomitant
Skin Papilloma Hospitalization 2/1/2010 78 Female 179 lb 11/3/2010 Physician Hungary
Primary
Secondary
Concomitant
Cerebral Infarction Other Serious 7/4/2010 70 Female 140 lb 11/9/2010 Physician United States
Primary
Secondary
Concomitant
Pregnancy Other Serious 10/14/2010 34 Female 119 lb 11/17/2010 Physician Japan
Primary
Secondary
Concomitant
Peritonitis Hospitalization 10/27/2007 50 Female 194 lb 11/30/2010 Physician France
Primary
Secondary
Concomitant
Large Intestinal Ulcer Other Serious 7/17/2010 61 Female 161 lb 11/30/2010 Physician Mexico
Primary
Secondary
Concomitant
Pelvic Fracture Hospitalization 7/30/2010 62 Female 12/16/2010 Physician Japan
Primary
Secondary
Concomitant
Gastritis Atrophic Hospitalization 10/11/2010 56 Female 12/16/2010 Physician Japan
Primary
Concomitant
Histiocytosis Haematophagic Life Threatening 11/23/2009 16 Female 121 lb 12/22/2010 Physician Italy
Primary
Secondary
Concomitant
Musculoskeletal Chest Pain Hospitalization 12/9/2010 49 Female 12/23/2010 Physician Japan
Primary
Concomitant
Lung Adenocarcinoma Life Threatening 12/9/2010 49 Female 12/28/2010 Physician Japan
Primary
Concomitant
Gastritis Atrophic Hospitalization 10/11/2010 56 Female 12/29/2010 Physician Japan
Primary
Concomitant
Pulmonary Veno-occlusive Disease Life Threatening 11/23/2009 16 Female 121 lb 1/25/2011 Physician Italy
Primary
Secondary
Concomitant
Lung Adenocarcinoma Hospitalization 12/9/2010 49 Female 1/26/2011 Physician Japan
Primary
Concomitant
Disseminated Intravascular Coagulation Death 1/5/2011 69 Female 1/26/2011 Other Health Professional Japan
Primary
Concomitant
Constipation Hospitalization 4/4/2010 78 Female 127 lb 2/28/2011 Physician United States
Primary
Secondary
Lung Adenocarcinoma Hospitalization 12/9/2010 49 Female 3/8/2011 Other Health Professional Japan
Primary
Concomitant
Musculoskeletal Chest Pain Hospitalization 2/18/2010 53 Female 182 lb 4/1/2011 Physician United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 4/3/2010 71 Male 152 lb 4/6/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 4/3/2010 71 Male 149 lb 4/8/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Abdominal Pain Hospitalization 9/14/2009 71 Male 200 lb 4/13/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 4/3/2010 71 Male 149 lb 4/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 11/9/2009 61 Female 116 lb 4/22/2011 Physician United States
Primary
Secondary
Concomitant
Peripheral Embolism Hospitalization 3/22/2011 52 Female 127 lb 4/22/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Colon Cancer Hospitalization 9/14/2009 71 Male 200 lb 4/26/2011 Physician United States
Primary
Secondary
Concomitant
Nephrolithiasis Hospitalization 6/20/2010 49 Male 198 lb 4/28/2011 Physician Lithuania
Primary
Secondary
Concomitant
Peripheral Embolism Hospitalization 3/22/2011 52 Female 127 lb 4/28/2011 Physician Japan
Primary
Secondary
Concomitant
Back Pain Hospitalization 12/15/2009 59 Female 158 lb 5/4/2011 Physician United States
Primary
Secondary
Concomitant
Osteomyelitis Hospitalization 12/15/2009 59 Female 158 lb 5/20/2011 Physician United States
Primary
Secondary
Concomitant
Death Death 4/17/2011 6 Male 40 lb 6/20/2011 Physician Australia
Primary
Secondary
Concomitant
Histiocytosis Haematophagic Hospitalization 3/28/2011 6 Female 44 lb 6/30/2011 Physician Germany
Primary
Secondary
Concomitant
Chest Pain Hospitalization 6/21/2011 62 Male 368 lb 6/30/2011 Physician Argentina
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 6/7/2011 46 Female 7/1/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Sepsis Death 4/17/2011 6 Male 40 lb 7/1/2011 Physician Australia
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 5/23/2011 46 Female 7/6/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Histiocytosis Haematophagic Hospitalization 3/28/2011 6 Female 44 lb 8/2/2011 Physician Germany
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 5/23/2011 46 Female 8/10/2011 Physician Japan
Primary
Secondary
Concomitant
Ligament Disorder Hospitalization 5/23/2011 46 Female 8/23/2011 Physician Japan
Primary
Secondary
Concomitant
Blood Bilirubin Increased Other Serious 8/9/2011 46 Female 139 lb 8/25/2011 Physician United Kingdom
Primary
Secondary
Blood Bilirubin Increased Other Serious 8/9/2011 46 Female 139 lb 9/14/2011 Physician United Kingdom
Primary
Secondary
Acute Myocardial Infarction Hospitalization 11/11/2011 52 Female 291 lb 1/8/2013 Physician Us
Primary
Secondary
Concomitant
Hyperlipidaemia Hospitalization 11/2011 54 Male 225 lb 5/30/2013 Physician Us
Primary
Secondary
Concomitant
Chillblains Hospitalization 1/23/2012 57 Male 172 lb 10/8/2013 Physician Fr
Primary
Secondary
Concomitant
Colitis Ulcerative Hospitalization 8/2/2012 55 Male 184 lb 3/13/2013 Physician Es
Primary
Secondary
Concomitant
Cholecystitis Acute Hospitalization 10/2/2012 28 Female 121 lb 12/26/2012 Physician Pa
Primary
Secondary
Concomitant
Renal Cyst Hospitalization 1/21/2011 62 Male 172 lb 8/23/2013 Physician Us
Primary
Secondary
Concomitant
Grand Mal Convulsion Life Threatening 9/19/2011 66 Male 198 lb 3/26/2013 Physician Ca
Primary
Secondary
Concomitant
Intervertebral Discitis Other Serious 11/14/2012 66 Female 150 lb 1/8/2013 Physician Mx
Primary
Secondary
Concomitant
Lymphadenitis Hospitalization 11/23/2012 31 Female 126 lb 6/19/2013 Physician Ru
Primary
Secondary
Concomitant
Acute Myocardial Infarction Death 1/1/2013 54 Female 293 lb 3/21/2013 Physician Br
Primary
Secondary
Concomitant
Ischaemic Stroke Hospitalization 8/15/2012 63 Male 194 lb 9/6/2013 Physician Fr
Primary
Secondary
Concomitant
Thoracic Vertebral Fracture Hospitalization 9/20/2012 77 Female 137 lb 3/8/2013 Physician Es
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Death 11/30/2012 67 Female 151 lb 4/2/2013 Physician Th
Primary
Secondary
Concomitant
Laceration Hospitalization 2/13/2013 33 Female 186 lb 3/21/2013 Physician Mx
Primary
Secondary
Concomitant
Thrombocytopenia Death 8/20/2012 68 Female 196 lb 9/17/2013 Physician Ca
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Hospitalization 12/2012 75 Female 154 lb 4/11/2013 Physician Br
Primary
Secondary
Concomitant
Respiratory Failure Disability 1/8/2013 82 Male 144 lb 9/20/2013 Physician Es
Primary
Secondary
Concomitant
Anal Squamous Cell Carcinoma Other Serious 1/8/2013 66 Female 148 lb 5/1/2013 Physician Br
Primary
Secondary
Concomitant
Intraductal Papilloma Of Breast Death 1/10/2013 52 Female 159 lb 6/18/2013 Physician My
Primary
Secondary
Concomitant
Renal Abscess Hospitalization 4/18/2012 38 Female 126 lb 8/17/2013 Physician Mx
Primary
Secondary
Concomitant
Small Cell Lung Cancer Death 2/16/2012 66 Female 160 lb 9/18/2013 Physician Us
Primary
Secondary
Concomitant
Sinusitis Other Serious 11/7/2011 60 Male 230 lb 10/25/2013 Physician Us
Primary
Secondary
Concomitant
Angina Pectoris Hospitalization 3/28/2012 61 Female 163 lb 12/11/2013 Physician Br
Primary
Secondary
Concomitant
Septic Shock Hospitalization 5/10/2012 70 Male 246 lb 9/9/2013 Physician Us
Primary
Secondary
Concomitant
Urosepsis Death 12/21/2010 68 Female 141 lb 9/24/2013 Physician Us
Primary
Secondary
Concomitant
Haemorrhagic Stroke Hospitalization 5/30/2013 76 Female 168 lb 9/3/2013 Physician Ar
Primary
Secondary
Concomitant

Drug Data