Rheumatrex combined with Tocilizumab

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tuberculosis Test Positive Other Serious 6/29/2008 Female 115 lb 7/9/2009 Physician Japan
Primary
Secondary
Concomitant
Rash Generalised Life Threatening 7/30/2008 Male 108 lb 1/20/2010 Physician Japan
Primary
Secondary
Concomitant
Cerebral Haemorrhage Other Serious 11/16/2009 Female 1/21/2010 Physician Japan
Primary
Concomitant
Nasopharyngitis Hospitalization 9/1/2008 Female 84 lb 1/26/2010 Physician Japan
Primary
Concomitant
Septic Shock Life Threatening 12/25/2008 Female 1/27/2010 Physician Japan
Primary
Concomitant
Subcutaneous Abscess Hospitalization 4/22/2009 Female 139 lb 2/2/2010 Physician Japan
Primary
Concomitant
Subdural Haematoma Hospitalization 9/17/2008 Female 93 lb 2/4/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 3/3/2009 Male 2/9/2010 Physician Japan
Primary
Secondary
Concomitant
Lymphoma Hospitalization 9/22/2009 Female 99 lb 2/9/2010 Physician Japan
Primary
Secondary
Concomitant
Pleurisy Hospitalization 12/16/2009 Female 2/9/2010 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 1/22/2010 Female 2/9/2010 Physician Japan
Primary
Secondary
Death Death Female 2/9/2010 Physician Japan
Primary
Concomitant
Lymphoma Hospitalization 11/9/2009 Female 93 lb 2/11/2010 Physician Japan
Primary
Concomitant
Dermatitis Bullous Hospitalization 4/26/2009 Female 126 lb 2/12/2010 Physician Japan
Primary
Secondary
Concomitant
Rash Generalised Life Threatening 7/30/2008 Male 108 lb 2/16/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Staphylococcal Other Serious 1/1/2009 Male 2/16/2010 Physician Japan
Primary
Secondary
Concomitant
C-reactive Protein Increased Other Serious 8/20/2008 Male 141 lb 2/17/2010 Physician Japan
Primary
Concomitant
Septic Shock Life Threatening 12/25/2008 Female 2/23/2010 Physician Japan
Primary
Secondary
Concomitant
Subdural Haematoma Hospitalization 9/17/2008 Female 93 lb 2/26/2010 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 1/19/2010 Female 3/3/2010 Physician Japan
Primary
Secondary
Systemic Mycosis Hospitalization 3/10/2009 Female 3/4/2010 Physician Japan
Primary
Secondary
Concomitant
Decubitus Ulcer Other Serious Female 3/4/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 2/22/2010 Female 3/5/2010 Physician Japan
Primary
Concomitant
Tuberculosis Test Positive Other Serious 6/29/2008 Female 115 lb 3/8/2010 Physician Japan
Primary
Secondary
Concomitant
Colitis Ulcerative Other Serious 12/16/2008 Male 126 lb 3/10/2010 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Other Serious 8/7/2008 Female 105 lb 3/12/2010 Physician Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 9/16/2009 Female 132 lb 3/15/2010 Physician Japan
Primary
Secondary
Concomitant
Cerebral Infarction Death 7/23/2009 Female 3/18/2010 Physician Japan
Primary
Concomitant
Jaundice Cholestatic Death 12/5/2008 Female 150 lb 3/19/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 5/1/2009 Female 3/23/2010 Physician Japan
Primary
Concomitant
Decubitus Ulcer Other Serious 11/4/2009 Female 3/23/2010 Physician Japan
Primary
Concomitant
Tonsillitis Other Serious 1/1/2009 Female 97 lb 3/23/2010 Other Health Professional Japan
Primary
Concomitant
Pneumonia Staphylococcal Death 10/19/2009 Male 3/24/2010 Physician Japan
Primary
Secondary
Concomitant
Non-hodgkin's Lymphoma Hospitalization 9/22/2009 Female 99 lb 3/29/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/28/2009 Female 3/30/2010 Physician Japan
Primary
Secondary
Concomitant
Cerebral Infarction Death 7/23/2009 83 Female 4/1/2010 Physician Japan
Primary
Concomitant
Glomerulonephritis Acute Other Serious 3/16/2010 61 Female 126 lb 4/6/2010 Physician Japan
Primary
Concomitant
Retroperitoneal Abscess Hospitalization 10/10/2009 78 Female 4/8/2010 Physician Japan
Primary
Concomitant
Tonsillitis Other Serious 1/1/2009 67 Female 97 lb 4/14/2010 Other Health Professional Japan
Primary
Concomitant
Rash Hospitalization 12/8/2008 53 Female 117 lb 4/15/2010 Physician Japan
Primary
Secondary
Concomitant
Lower Gastrointestinal Haemorrhage Hospitalization Female 143 lb 4/21/2010 Physician Japan
Primary
Concomitant
Oral Herpes Other Serious 8/13/2008 66 Female 143 lb 4/22/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/28/2009 75 Female 4/23/2010 Physician Japan
Primary
Secondary
Concomitant
Varicose Vein Other Serious 9/26/2008 61 Female 150 lb 4/23/2010 Physician Japan
Primary
Concomitant
Lower Gastrointestinal Haemorrhage Hospitalization Female 143 lb 4/27/2010 Physician Japan
Primary
Concomitant
Cerebral Infarction Hospitalization 4/4/2010 70 Female 132 lb 4/29/2010 Physician Japan
Primary
Concomitant
Rash Hospitalization 12/8/2008 53 Female 117 lb 5/6/2010 Physician Japan
Primary
Secondary
Concomitant
Pain In Extremity Life Threatening 7/1/2009 69 Female 112 lb 5/7/2010 Physician Japan
Primary
Concomitant
Tonsillitis Other Serious 1/1/2009 67 Female 97 lb 5/10/2010 Other Health Professional Japan
Primary
Concomitant
Subcutaneous Abscess Hospitalization 4/22/2009 53 Female 139 lb 5/12/2010 Physician Japan
Primary
Concomitant
Histiocytosis Haematophagic Death 4/30/2009 71 Female 5/19/2010 Physician Japan
Primary
Concomitant
Septic Shock Life Threatening 7/7/2008 15 Female 95 lb 5/19/2010 Physician Japan
Primary
Concomitant
Oral Herpes Other Serious 8/13/2008 66 Female 143 lb 5/20/2010 Physician Japan
Primary
Secondary
Concomitant
Tonsillitis Other Serious 5/20/2009 67 Female 97 lb 5/21/2010 Other Health Professional Japan
Primary
Concomitant
Hepatic Function Abnormal Other Serious 9/16/2009 53 Female 132 lb 5/25/2010 Physician Japan
Primary
Secondary
Concomitant
Hypercholesterolaemia Other Serious 11/10/2009 56 Female 5/27/2010 Physician Japan
Primary
Concomitant
Hypertriglyceridaemia 9/26/2008 61 Female 150 lb 5/27/2010 Physician Japan
Primary
Concomitant
Peritonitis Bacterial Hospitalization 10/10/2009 78 Female 6/3/2010 Physician Japan
Primary
Secondary
Concomitant
Oral Herpes Other Serious 8/13/2008 66 Female 143 lb 6/9/2010 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 1/19/2010 50 Female 6/9/2010 Physician Japan
Primary
Secondary
Concomitant
Pain In Extremity Life Threatening 7/1/2009 69 Female 112 lb 6/10/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/5/2009 60 Male 152 lb 6/14/2010 Other Health Professional Japan
Primary
Concomitant
Cardiac Failure Acute Death 10/2/2009 58 Male 6/16/2010 Physician Japan
Primary
Concomitant
Sepsis Hospitalization 5/11/2010 4 Female 6/18/2010 Physician Japan
Primary
Secondary
Concomitant
Sudden Hearing Loss Other Serious 5/20/2009 67 Female 97 lb 6/30/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 12/28/2009 65 Female 128 lb 7/2/2010 Physician Japan
Primary
Secondary
Concomitant
Palpitations Other Serious 10/17/2008 37 Female 7/2/2010 Physician Japan
Primary
Concomitant
Palpitations Other Serious 10/17/2008 37 Female 7/6/2010 Physician Japan
Primary
Concomitant
Malaise Hospitalization 3/19/2009 51 Female 110 lb 7/9/2010 Physician Japan
Primary
Concomitant
Neutropenia Hospitalization 5/16/2010 4 Female 7/10/2010 Physician Japan
Primary
Secondary
Concomitant
Spinal Compression Fracture Hospitalization 12/4/2009 66 Female 77 lb 7/13/2010 Physician Japan
Primary
Concomitant
Pruritus Hospitalization 1/16/2009 63 Female 130 lb 7/16/2010 Physician Japan
Primary
Secondary
Concomitant
Ileus Hospitalization 10/26/2009 59 Female 110 lb 7/16/2010 Physician Japan
Primary
Concomitant
Lymph Node Tuberculosis 4/10/2009 61 Female 7/21/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/7/2009 45 Female 95 lb 7/21/2010 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 10/30/2009 69 Female 126 lb 7/22/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 2/22/2010 66 Female 7/29/2010 Physician Japan
Primary
Concomitant
Cerebral Infarction Hospitalization 4/2/2010 70 Female 134 lb 7/29/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 2/22/2010 66 Female 119 lb 7/30/2010 Physician Japan
Primary
Concomitant
Histiocytosis Haematophagic Hospitalization 7/21/2010 21 Female 8/3/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 4/27/2010 70 Female 8/5/2010 Physician Japan
Primary
Secondary
Concomitant
Postoperative Wound Infection Other Serious 12/1/2009 60 Female 119 lb 8/6/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 3/3/2009 67 Male 8/11/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 10/8/2008 44 Female 106 lb 8/13/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/5/2009 60 Male 152 lb 8/18/2010 Physician Japan
Primary
Concomitant
Platelet Count Decreased Life Threatening 1/19/2009 73 Male 8/18/2010 Physician Japan
Primary
Concomitant
Oral Discomfort Life Threatening 6/26/2008 63 Female 99 lb 8/25/2010 Physician Japan
Primary
Concomitant
Urinary Tract Infection Life Threatening 8/7/2009 70 Female 8/30/2010 Physician Japan
Primary
Concomitant
Ileus Hospitalization 2/22/2010 66 Female 119 lb 8/30/2010 Physician Japan
Primary
Concomitant
Sepsis Other Serious 6/5/2010 67 Female 93 lb 9/2/2010 Physician Japan
Primary
Secondary
Concomitant
Postoperative Wound Infection Other Serious 12/1/2009 60 Female 119 lb 9/4/2010 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 1/19/2010 50 Female 9/7/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 11/30/2009 65 Female 128 lb 9/8/2010 Physician Japan
Primary
Secondary
Concomitant
Thyroid Neoplasm Hospitalization 9/1/2010 69 Female 172 lb 9/8/2010 Physician Japan
Primary
Concomitant
Sudden Hearing Loss Other Serious 5/20/2009 67 Female 97 lb 9/14/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Other Serious 10/2/2009 58 Male 9/17/2010 Physician Japan
Primary
Concomitant
Glomerulonephritis Acute Other Serious 3/16/2010 61 Female 126 lb 9/23/2010 Physician Japan
Primary
Concomitant
Agranulocytosis Hospitalization 7/6/2009 78 Female 132 lb 9/24/2010 Physician Japan
Primary
Concomitant
Viral Infection Other Serious 6/25/2008 13 Male 112 lb 9/24/2010 Physician Japan
Primary
Concomitant
Palpitations Hospitalization 10/17/2008 37 Female 9/29/2010 Physician Japan
Primary
Concomitant
Diffuse Large B-cell Lymphoma Hospitalization 11/9/2009 38 Female 93 lb 10/5/2010 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 1/19/2009 73 Male 10/5/2010 Physician Japan
Primary
Concomitant
Ileus Hospitalization 10/26/2009 59 Female 110 lb 10/7/2010 Physician Japan
Primary
Concomitant
Malaise Hospitalization 3/19/2009 51 Female 110 lb 10/8/2010 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 1/19/2009 73 Male 10/12/2010 Physician Japan
Primary
Secondary
Concomitant
Colitis Ulcerative Other Serious 12/16/2008 64 Male 126 lb 10/13/2010 Physician Japan
Primary
Concomitant
Histiocytosis Haematophagic Death 4/30/2009 71 Female 10/14/2010 Physician Japan
Primary
Concomitant
Melaena Other Serious 2/6/2009 82 Male 10/14/2010 Physician Japan
Primary
Concomitant
Thyroid Neoplasm Hospitalization 8/1/2010 69 Female 172 lb 10/15/2010 Other Health Professional Japan
Primary
Concomitant
Tinea Pedis Hospitalization 4/2/2009 69 Female 105 lb 10/15/2010 Physician Japan
Primary
Concomitant
Rash Generalised Life Threatening 7/30/2008 56 Male 108 lb 10/18/2010 Physician Japan
Primary
Secondary
Concomitant
Melaena Other Serious 2/6/2009 82 Male 10/19/2010 Physician Japan
Primary
Concomitant
Neoplasm Malignant Life Threatening 9/22/2008 53 Female 153 lb 10/19/2010 Physician Japan
Primary
Concomitant
Urinary Tract Infection Hospitalization 3/7/2009 47 Male 10/26/2010 Physician Japan
Primary
Concomitant
Tinea Manuum Hospitalization 2/17/2010 76 Female 10/28/2010 Physician Japan
Primary
Concomitant
Melaena Other Serious 2/6/2009 82 Male 10/28/2010 Physician Japan
Primary
Concomitant
Urticaria Other Serious 1/1/2009 42 Female 11/11/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Disorder Hospitalization 3/1/2010 61 Female 134 lb 11/15/2010 Physician Japan
Primary
Concomitant
Spinal Compression Fracture Hospitalization 12/4/2009 66 Female 77 lb 11/16/2010 Physician Japan
Primary
Concomitant
Thyroid Neoplasm Hospitalization 8/11/2010 69 Female 181 lb 11/19/2010 Other Health Professional Japan
Primary
Concomitant
Tinea Manuum 2/17/2010 76 Female 11/22/2010 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 1/19/2009 73 Male 11/23/2010 Physician Japan
Primary
Secondary
Concomitant
Metastases To Liver Other Serious 1/1/2007 73 Female 104 lb 11/30/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Cell Carcinoma Life Threatening 9/22/2008 53 Female 153 lb 12/1/2010 Physician Japan
Primary
Secondary
Concomitant
Subdural Haematoma Hospitalization 9/17/2008 70 Female 93 lb 12/3/2010 Physician Japan
Primary
Secondary
Concomitant
Pustular Psoriasis Hospitalization 3/1/2009 71 Female 110 lb 12/13/2010 Physician Japan
Primary
Secondary
Concomitant
Viral Infection Hospitalization 6/25/2008 13 Male 112 lb 12/20/2010 Physician Japan
Primary
Concomitant
Sudden Hearing Loss Hospitalization 5/20/2009 67 Female 97 lb 1/18/2011 Physician Japan
Primary
Secondary
Concomitant
Cytomegalovirus Infection Hospitalization 3/3/2010 61 Female 134 lb 1/31/2011 Other Health Professional Japan
Primary
Concomitant
Anaphylactic Shock Hospitalization 6/1/2009 44 Female 104 lb 2/2/2011 Physician Japan
Primary
Concomitant
Non-hodgkin's Lymphoma Hospitalization 9/22/2009 62 Female 99 lb 2/23/2011 Physician Japan
Primary
Secondary
Concomitant
Brain Abscess Other Serious 1/1/2007 73 Female 104 lb 2/28/2011 Physician Japan
Primary
Secondary
Concomitant
Joint Destruction Hospitalization 2/24/2011 48 Female 99 lb 3/8/2011 Physician Japan
Primary
Secondary
Concomitant
Arthritis Hospitalization 11/2/2010 5 Female 38 lb 3/17/2011 Physician Japan
Primary
Secondary
Concomitant
Joint Destruction Hospitalization 9/17/2008 70 Female 93 lb 3/29/2011 Physician Japan
Primary
Secondary
Concomitant
Immune System Disorder Other Serious 3/7/2009 47 Male 4/7/2011 Other Health Professional Japan
Primary
Concomitant
Hypertriglyceridaemia Hospitalization 9/17/2008 70 Female 93 lb 4/15/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Arthritis Hospitalization 2/1/2009 72 Male 4/18/2011 Physician Japan
Primary
Secondary
Concomitant
Oral Discomfort Life Threatening 6/26/2008 63 Female 99 lb 4/20/2011 Other Health Professional Japan
Primary
Concomitant
Blood Urea Increased Death 6/12/2009 70 Male 4/20/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Headache Death 6/12/2009 70 Male 162 lb 5/23/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Liver Disorder Other Serious 1/24/2011 7 Male 5/19/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Juvenile Arthritis Hospitalization 11/2/2010 5 Female 38 lb 5/27/2011 Physician Japan
Primary
Secondary
Concomitant
Haemorrhage Subcutaneous Hospitalization 4/28/2009 75 Female 5/31/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Organising Pneumonia Hospitalization 2/1/2010 63 Male 143 lb 6/3/2011 Other Health Professional Japan
Primary
Concomitant
Eczema Death 6/12/2009 70 Male 162 lb 6/8/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Neutropenia Other Serious 4/1/2011 64 Male 6/9/2011 Physician Japan
Primary
Concomitant
Cell Marker Increased Other Serious 10/19/2010 77 Female 6/20/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Organising Pneumonia Hospitalization 2/22/2010 63 Male 143 lb 6/29/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Respiratory Failure Death 11/18/2010 66 Male 7/7/2011 Other Health Professional Japan
Primary
Concomitant

Drug Data