Predonine combined with Tocilizumab

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Decreased Life Threatening 9/8/2005 34 Male 136 lb 3/3/2006 Physician Japan
Primary
Secondary
Concomitant
Thalamic Infarction Hospitalization 11/29/2005 53 Female 159 lb 9/15/2006 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 9/29/2008 Female 1/23/2009 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 9/29/2008 Female 2/20/2009 Physician Japan
Primary
Secondary
Concomitant
Still's Disease Adult Onset Hospitalization 9/29/2008 Female 2/27/2009 Physician Japan
Primary
Secondary
Concomitant
Still's Disease Adult Onset Hospitalization 9/29/2008 Female 1/4/2010 Physician Japan
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 7/4/2008 Female 77 lb 1/18/2010 Physician Japan
Primary
Secondary
Concomitant
Rash Generalised Life Threatening 7/30/2008 Male 108 lb 1/20/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 9/8/2008 Female 9 lb 1/20/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 10/18/2009 Female 86 lb 1/22/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 8/7/2008 Male 117 lb 1/22/2010 Physician Japan
Primary
Secondary
Concomitant
Septic Shock Life Threatening 12/25/2008 Female 1/27/2010 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 8/11/2008 Female 1/29/2010 Physician Japan
Primary
Secondary
Concomitant
Herpes Zoster Hospitalization 10/25/2009 Female 1/29/2010 Physician Japan
Primary
Secondary
Concomitant
Intestinal Ulcer Other Serious 6/29/2008 Male 2/1/2010 Physician Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 1/1/2009 Female 86 lb 2/1/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/4/2009 Female 2/1/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 8/7/2008 Male 117 lb 2/2/2010 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 1/20/2010 Male 2/2/2010 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 11/4/2009 Female 2/3/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 3/3/2009 Male 2/9/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 8/7/2008 Male 117 lb 2/11/2010 Physician Japan
Primary
Secondary
Concomitant
Septic Shock Hospitalization 12/9/2008 Male 2/12/2010 Physician Japan
Primary
Secondary
Concomitant
Dermatitis Bullous Hospitalization 4/26/2009 Female 126 lb 2/12/2010 Physician Japan
Primary
Secondary
Concomitant
Rash Generalised Life Threatening 7/30/2008 Male 108 lb 2/16/2010 Physician Japan
Primary
Secondary
Concomitant
Septic Shock Hospitalization 1/5/2010 Female 2/16/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/4/2009 Female 2/16/2010 Physician Japan
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 1/19/2009 Male 185 lb 2/16/2010 Physician Japan
Primary
Concomitant
Sepsis Other Serious 7/3/2009 Male 174 lb 2/19/2010 Physician Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 7/3/2009 Male 174 lb 2/19/2010 Physician Japan
Primary
Secondary
Concomitant
Herpes Zoster Hospitalization 10/25/2009 Female 106 lb 2/19/2010 Physician Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 7/3/2009 Male 174 lb 2/19/2010 Physician Japan
Primary
Secondary
Concomitant
Septic Shock Life Threatening 12/25/2008 Female 2/23/2010 Physician Japan
Primary
Secondary
Concomitant
Pyelonephritis Hospitalization 12/14/2009 Female 2/23/2010 Physician Japan
Primary
Concomitant
Subcutaneous Abscess Other Serious 10/16/2009 Female 2/25/2010 Other Health Professional Japan
Primary
Concomitant
Sepsis Other Serious 2/15/2009 Male 165 lb 2/26/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 8/14/2009 Female 2/26/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Other Serious 8/23/2009 Female 95 lb 3/3/2010 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 1/1/2009 Female 3/3/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/11/2008 Female 53 lb 3/3/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/11/2008 Female 53 lb 3/3/2010 Physician Japan
Primary
Secondary
Concomitant
Venous Thrombosis Limb Other Serious 2/13/2009 Male 108 lb 3/4/2010 Physician Japan
Primary
Secondary
Concomitant
Systemic Mycosis Hospitalization 3/10/2009 Female 3/4/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 2/22/2010 Female 3/5/2010 Physician Japan
Primary
Concomitant
Tuberculosis Test Positive Other Serious 6/29/2008 Female 115 lb 3/8/2010 Physician Japan
Primary
Secondary
Concomitant
Musculoskeletal Stiffness Hospitalization 6/20/2008 Male 3/8/2010 Physician Japan
Primary
Secondary
Concomitant
Vasculitis Other Serious 7/1/2008 Male 132 lb 3/9/2010 Other Health Professional Japan
Primary
Concomitant
Colitis Ulcerative Other Serious 12/16/2008 Male 126 lb 3/10/2010 Physician Japan
Primary
Concomitant
Gastric Perforation Life Threatening 5/14/2009 Female 95 lb 3/11/2010 Physician Japan
Primary
Secondary
Concomitant
Uterine Cancer Hospitalization 12/21/2009 Female 99 lb 3/11/2010 Other Health Professional Japan
Primary
Secondary
Vomiting Other Serious 9/8/2008 Female 9 lb 3/15/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Septic Shock Hospitalization 12/9/2008 Male 132 lb 3/23/2010 Physician Japan
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 10/20/2009 56 Male 3/23/2010 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 1/20/2010 Male 3/24/2010 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 8/14/2009 Female 3/24/2010 Physician Japan
Primary
Secondary
Concomitant
Upper Respiratory Tract Inflammation Life Threatening 2/12/2009 71 Male 4/6/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 2/1/2010 12 Male 4/6/2010 Physician Japan
Primary
Concomitant
Colitis Ulcerative Hospitalization 2/2/2010 58 Female 143 lb 4/6/2010 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 9/17/2009 57 Male 108 lb 4/12/2010 Physician Japan
Primary
Concomitant
Herpes Zoster Hospitalization 10/24/2008 78 Female 123 lb 4/13/2010 Physician Japan
Primary
Secondary
Concomitant
Ulnar Neuritis Other Serious 7/7/2009 40 Male 203 lb 4/14/2010 Physician Japan
Primary
Secondary
Concomitant
Rash Hospitalization 12/8/2008 53 Female 117 lb 4/15/2010 Physician Japan
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 6/9/2008 58 Male 154 lb 4/16/2010 Physician Japan
Primary
Concomitant
Myocardial Infarction Death 1/1/2008 68 Female 99 lb 4/20/2010 Other Health Professional Japan
Primary
Concomitant
Sepsis Other Serious 7/3/2009 45 Male 174 lb 4/20/2010 Physician Japan
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Hospitalization 5/8/2009 80 Female 108 lb 4/21/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/7/2009 60 Female 4/21/2010 Physician Japan
Primary
Concomitant
Lower Gastrointestinal Haemorrhage Hospitalization Female 143 lb 4/21/2010 Physician Japan
Primary
Concomitant
Oral Herpes Other Serious 8/13/2008 66 Female 143 lb 4/22/2010 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 3/16/2010 14 Male 4/22/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/28/2009 75 Female 4/23/2010 Physician Japan
Primary
Secondary
Concomitant
Varicose Vein Other Serious 9/26/2008 61 Female 150 lb 4/23/2010 Physician Japan
Primary
Concomitant
Respiratory Failure Hospitalization 10/7/2009 65 Male 4/27/2010 Physician Japan
Primary
Secondary
Concomitant
Lower Gastrointestinal Haemorrhage Hospitalization Female 143 lb 4/27/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 11/20/2009 38 Female 4/28/2010 Physician Japan
Primary
Concomitant
Cerebral Infarction Hospitalization 4/4/2010 70 Female 132 lb 4/29/2010 Physician Japan
Primary
Concomitant
Enterocolitis Hospitalization 4/21/2010 7 Male 51 lb 4/30/2010 Physician Japan
Primary
Concomitant
Small Intestinal Perforation Life Threatening 6/22/2009 74 Male 4/30/2010 Physician Japan
Primary
Secondary
Concomitant
Enterocolitis Hospitalization 4/21/2010 7 Male 51 lb 5/3/2010 Physician Japan
Primary
Concomitant
Enterocolitis Hospitalization 4/21/2010 7 Male 51 lb 5/5/2010 Physician Japan
Primary
Concomitant
Rash Hospitalization 12/8/2008 53 Female 117 lb 5/6/2010 Physician Japan
Primary
Secondary
Concomitant
Death Death 3/1/2010 70 Female 5/12/2010 Physician Japan
Primary
Concomitant
Still's Disease Adult Onset Hospitalization 9/29/2008 72 Female 5/12/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 2/1/2010 12 Male 5/18/2010 Physician Japan
Primary
Concomitant
Septic Shock Life Threatening 7/7/2008 15 Female 95 lb 5/19/2010 Physician Japan
Primary
Concomitant
Small Cell Lung Cancer Stage Unspecified Death 4/23/2010 66 Male 5/19/2010 Other Health Professional Japan
Primary
Concomitant
Oral Herpes Other Serious 8/13/2008 66 Female 143 lb 5/20/2010 Physician Japan
Primary
Secondary
Concomitant
Uterine Cancer Hospitalization 12/21/2009 47 Female 99 lb 5/21/2010 Other Health Professional Japan
Primary
Secondary
Liver Disorder Other Serious 3/16/2010 14 Male 5/24/2010 Physician Japan
Primary
Concomitant
Bile Duct Cancer Death Female 5/24/2010 Physician Japan
Primary
Concomitant
Colitis Ulcerative Hospitalization 2/2/2010 58 Female 143 lb 5/27/2010 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 8/14/2009 52 Female 5/27/2010 Physician Japan
Primary
Secondary
Concomitant
Hypertriglyceridaemia 9/26/2008 61 Female 150 lb 5/27/2010 Physician Japan
Primary
Concomitant
Cerebral Infarction Hospitalization Female 6/3/2010 Physician Japan
Primary
Concomitant
Vision Blurred Hospitalization 8/11/2009 62 Female 110 lb 6/8/2010 Physician Japan
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 1/20/2010 78 Male 132 lb 6/9/2010 Physician Japan
Primary
Concomitant
Oral Herpes Other Serious 8/13/2008 66 Female 143 lb 6/9/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Life Threatening 3/1/2010 70 Female 6/16/2010 Physician Japan
Primary
Concomitant
Cerebral Infarction Hospitalization 3/28/2010 74 Female 6/16/2010 Physician Japan
Primary
Concomitant
Renal Impairment Hospitalization 8/7/2008 70 Male 117 lb 6/18/2010 Physician Japan
Primary
Secondary
Concomitant
Colitis Ulcerative Hospitalization 2/2/2010 58 Female 143 lb 6/21/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/15/2010 18 Female 6/22/2010 Physician Japan
Primary
Concomitant
Renal Failure Other Serious 4/13/2009 69 Female 93 lb 6/22/2010 Physician Japan
Primary
Concomitant
Stasis Dermatitis Other Serious 12/17/2008 61 Male 6/25/2010 Physician Japan
Primary
Concomitant
Hyperhidrosis Hospitalization 10/28/2009 51 Male 117 lb 6/25/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 11/20/2009 38 Female 95 lb 6/29/2010 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 9/17/2009 57 Male 108 lb 6/30/2010 Physician Japan
Primary
Concomitant
Convulsion Hospitalization 7/14/2009 66 Male 7/1/2010 Physician Japan
Primary
Concomitant
Suicide Attempt Life Threatening 1/23/2010 70 Male 143 lb 7/1/2010 Physician Japan
Primary
Secondary
Concomitant
Lymphocyte Count Decreased Other Serious Male 140 lb 7/2/2010 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 12/28/2009 65 Female 128 lb 7/2/2010 Physician Japan
Primary
Secondary
Concomitant
Palpitations Other Serious 10/17/2008 37 Female 7/2/2010 Physician Japan
Primary
Concomitant
Palpitations Other Serious 10/17/2008 37 Female 7/6/2010 Physician Japan
Primary
Concomitant
Rash Hospitalization 7/19/2008 72 Female 93 lb 7/6/2010 Physician Japan
Primary
Secondary
Concomitant
Haemoptysis Death 6/8/2010 69 Male 126 lb 7/7/2010 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 10/24/2008 78 Female 123 lb 7/8/2010 Physician Japan
Primary
Secondary
Concomitant
Ulnar Neuritis Other Serious 7/7/2009 40 Male 236 lb 7/9/2010 Physician Japan
Primary
Secondary
Concomitant
Malaise Hospitalization 3/19/2009 51 Female 110 lb 7/9/2010 Physician Japan
Primary
Concomitant
Septic Shock Hospitalization 1/5/2010 68 Female 7/10/2010 Physician Japan
Primary
Secondary
Concomitant
Lymphocyte Count Decreased Other Serious 2/18/2010 47 Male 151 lb 7/12/2010 Physician Japan
Primary
Secondary
Concomitant
Breast Cancer Hospitalization 3/4/2010 63 Female 7/16/2010 Physician Japan
Primary
Concomitant
Lymphocyte Count Decreased Other Serious Male 140 lb 7/19/2010 Physician Japan
Primary
Concomitant
Lung Neoplasm Malignant Hospitalization Female 7/19/2010 Physician Japan
Primary
Concomitant
Spinal Compression Fracture Hospitalization 8/13/2009 61 Female 7/22/2010 Physician Japan
Primary
Secondary
Concomitant
Haemoptysis Death 6/8/2010 69 Male 126 lb 7/22/2010 Physician Japan
Primary
Concomitant
Ulcerative Keratitis Other Serious 1/1/2008 62 Male 7/23/2010 Physician Japan
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 1/1/2010 68 Female 152 lb 7/23/2010 Physician Japan
Primary
Concomitant
Retinal Detachment Hospitalization 12/28/2009 55 Male 118 lb 7/23/2010 Physician Japan
Primary
Secondary
Concomitant
Upper Respiratory Tract Inflammation Other Serious 4/1/2004 63 Male 7/29/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 2/22/2010 66 Female 7/29/2010 Physician Japan
Primary
Concomitant
Cerebral Infarction Hospitalization 4/2/2010 70 Female 134 lb 7/29/2010 Physician Japan
Primary
Concomitant
Lymphocyte Count Decreased Other Serious Male 119 lb 7/30/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 2/22/2010 66 Female 119 lb 7/30/2010 Physician Japan
Primary
Concomitant
Thrombocytopenia Hospitalization 1/24/2010 76 Female 112 lb 7/30/2010 Physician Japan
Primary
Concomitant
Histiocytosis Haematophagic Other Serious 8/20/2009 36 Female 8/2/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 4/27/2010 70 Female 8/5/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/15/2010 18 Female 87 lb 8/6/2010 Physician Japan
Primary
Concomitant
Diarrhoea Other Serious 5/12/2009 75 Female 108 lb 8/6/2010 Physician Japan
Primary
Concomitant
Sciatica Life Threatening 1/1/2008 68 Female 8/6/2010 Physician Japan
Primary
Concomitant
Postoperative Wound Infection Other Serious 12/1/2009 60 Female 119 lb 8/6/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 3/3/2009 67 Male 8/11/2010 Physician Japan
Primary
Secondary
Concomitant
Lymphocyte Count Decreased Other Serious Female 8/11/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/15/2010 18 Female 87 lb 8/12/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/8/2008 44 Female 106 lb 8/13/2010 Physician Japan
Primary
Concomitant
Lymphopenia Other Serious 6/17/2010 15 Male 120 lb 8/18/2010 Physician Japan
Primary
Secondary
Pyrexia Other Serious Male 140 lb 8/19/2010 Physician Japan
Primary
Concomitant
Spinal Compression Fracture Hospitalization 8/13/2009 61 Female 8/23/2010 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Other Serious 3/16/2010 14 Male 117 lb 8/23/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/7/2009 60 Female 8/23/2010 Physician Japan
Primary
Concomitant
Sciatica Life Threatening 3/19/2010 70 Female 86 lb 8/23/2010 Physician Japan
Primary
Concomitant

Drug Data