| Primary |
| Product Used For Unknown Indication |
27.4% |
| Gastrooesophageal Reflux Disease |
22.4% |
| Hypertension |
7.7% |
| Helicobacter Infection |
6.1% |
| Prophylaxis |
5.9% |
| Gastritis |
4.2% |
| Prophylaxis Against Gastrointestinal Ulcer |
3.4% |
| Dyspepsia |
3.0% |
| Chronic Obstructive Pulmonary Disease |
2.8% |
| Pain |
2.5% |
| Acute Coronary Syndrome |
1.9% |
| Hiatus Hernia |
1.6% |
| Peptic Ulcer |
1.6% |
| Urinary Tract Infection |
1.6% |
| Duodenal Ulcer |
1.5% |
| Oesophagitis |
1.4% |
| Barrett's Oesophagus |
1.3% |
| Depression |
1.3% |
| Pneumonia |
1.3% |
| Gastric Disorder |
1.2% |
|
| Death |
16.1% |
| Drug Ineffective |
15.0% |
| Product Substitution Issue |
6.4% |
| Renal Failure Acute |
6.2% |
| Malaise |
5.9% |
| Nausea |
4.8% |
| Agranulocytosis |
4.3% |
| Hypomagnesaemia |
4.3% |
| Vomiting |
4.0% |
| Drug Interaction |
3.8% |
| Weight Decreased |
3.5% |
| Neutropenia |
3.2% |
| Tubulointerstitial Nephritis |
3.2% |
| Diarrhoea |
2.9% |
| Hyponatraemia |
2.9% |
| Thrombocytopenia |
2.9% |
| Myocardial Infarction |
2.7% |
| Pruritus |
2.7% |
| Suicide Attempt |
2.7% |
| Renal Failure |
2.4% |
|
| Secondary |
| Product Used For Unknown Indication |
49.6% |
| Gastrooesophageal Reflux Disease |
8.3% |
| Hypertension |
7.4% |
| Drug Use For Unknown Indication |
5.0% |
| Prophylaxis |
4.0% |
| Pain |
3.6% |
| Maternal Exposure During Pregnancy |
2.2% |
| Helicobacter Infection |
2.1% |
| Hyperemesis Gravidarum |
1.9% |
| Prophylaxis Against Gastrointestinal Ulcer |
1.8% |
| Asthma |
1.7% |
| Chronic Obstructive Pulmonary Disease |
1.7% |
| Depression |
1.5% |
| Barrett's Oesophagus |
1.5% |
| Dyspepsia |
1.5% |
| Psoriasis |
1.3% |
| Acute Myocardial Infarction |
1.3% |
| Pancreatitis |
1.3% |
| Gastritis |
1.2% |
| Osteoporosis |
1.2% |
|
| Completed Suicide |
9.9% |
| Tetany |
8.6% |
| Renal Failure Acute |
7.0% |
| Drug Ineffective |
6.4% |
| Angioedema |
6.2% |
| Toxic Epidermal Necrolysis |
6.2% |
| Vomiting |
6.2% |
| Death |
5.1% |
| Suicide Attempt |
4.8% |
| Diarrhoea |
4.3% |
| Toxicity To Various Agents |
4.3% |
| Drug Rash With Eosinophilia And Systemic Symptoms |
4.0% |
| Hypomagnesaemia |
3.8% |
| Malaise |
3.8% |
| Pancreatitis |
3.8% |
| Thrombocytopenia |
3.5% |
| Convulsion |
3.2% |
| Leukopenia |
3.2% |
| Gastrooesophageal Reflux Disease |
2.9% |
| Product Substitution Issue |
2.9% |
|
| Concomitant |
| Product Used For Unknown Indication |
43.6% |
| Drug Use For Unknown Indication |
15.4% |
| Hypertension |
6.9% |
| Prophylaxis |
4.7% |
| Rheumatoid Arthritis |
4.7% |
| Pain |
4.1% |
| Gastrooesophageal Reflux Disease |
2.3% |
| Depression |
1.9% |
| Atrial Fibrillation |
1.8% |
| Diabetes Mellitus |
1.8% |
| Crohn's Disease |
1.8% |
| Osteoporosis |
1.5% |
| Diffuse Large B-cell Lymphoma |
1.4% |
| Nausea |
1.4% |
| Multiple Myeloma |
1.4% |
| Constipation |
1.2% |
| Thrombosis Prophylaxis |
1.0% |
| Insomnia |
1.0% |
| Chronic Obstructive Pulmonary Disease |
1.0% |
| Non-small Cell Lung Cancer |
1.0% |
|
| Vomiting |
14.5% |
| Weight Decreased |
8.1% |
| Death |
6.9% |
| Pneumonia |
5.8% |
| Urinary Tract Infection |
5.2% |
| Pyrexia |
5.1% |
| Renal Failure Acute |
5.1% |
| Nausea |
4.8% |
| Pulmonary Embolism |
4.7% |
| Thrombocytopenia |
4.6% |
| Sepsis |
4.5% |
| Pain |
4.1% |
| Weight Increased |
4.0% |
| Renal Failure |
3.9% |
| Diarrhoea |
3.3% |
| Myocardial Infarction |
3.3% |
| Dyspnoea |
3.2% |
| Drug Ineffective |
3.0% |
| Syncope |
2.9% |
| Anaemia |
2.9% |
|
| Interacting |
| Hypertension |
13.4% |
| Product Used For Unknown Indication |
10.2% |
| Pneumonia |
10.0% |
| Acute Coronary Syndrome |
8.9% |
| Prophylaxis Against Gastrointestinal Ulcer |
7.3% |
| Ischaemic Heart Disease Prophylaxis |
5.5% |
| Hepatitis C |
4.7% |
| Urinary Tract Infection |
4.5% |
| Helicobacter Infection |
4.2% |
| Chronic Obstructive Pulmonary Disease |
3.9% |
| Pain |
3.4% |
| Prophylaxis |
3.4% |
| Haemorrhage |
3.1% |
| Schizophrenia |
3.1% |
| Zygomycosis |
3.1% |
| Neck Pain |
2.4% |
| Precursor T-lymphoblastic Lymphoma/leukaemia |
2.4% |
| Agitation |
2.1% |
| Angina Pectoris |
2.1% |
| Gastric Haemorrhage |
2.1% |
|
| Drug Interaction |
31.3% |
| Hepatitis Cholestatic |
7.5% |
| Vomiting |
7.5% |
| Clostridium Difficile Colitis |
6.3% |
| Melaena |
5.0% |
| Rhabdomyolysis |
5.0% |
| Dry Mouth |
3.8% |
| Pseudomembranous Colitis |
3.8% |
| Renal Failure |
3.8% |
| Renal Failure Acute |
3.8% |
| Toxicity To Various Agents |
3.8% |
| General Physical Health Deterioration |
2.5% |
| Hyponatraemia |
2.5% |
| Malaise |
2.5% |
| Obstruction |
2.5% |
| Pancytopenia |
2.5% |
| Therapeutic Procedure |
2.5% |
| Abdominal Pain |
1.3% |
| Agitation |
1.3% |
| Blood Creatinine Increased |
1.3% |
|
