Alprazolam combined with Pantoprazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 11/23/2004 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 11/23/2004 1/6/2006 Physician United States
Primary
Concomitant
Syncope Other Serious 7/26/2005 Male 2/3/2006 Puerto Rico
Primary
Concomitant
Pleural Effusion Other Serious 7/26/2005 Male 215 lb 2/16/2006 Puerto Rico
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 1/14/2006 41 Female 150 lb 3/22/2006 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Other Serious 7/26/2005 Male 215 lb 4/7/2006 Puerto Rico
Primary
Concomitant
Nausea Other Serious 1/14/2006 41 Female 150 lb 4/4/2006 Pharmacist United States
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization 3/13/2006 94 Female 6/5/2006 Other Health Professional France
Primary
Secondary
Concomitant
Initial Insomnia 7/1/2006 60 Female 220 lb 1/12/2007 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 3/16/2006 Female 88 lb 5/9/2007 Korea, Republic Of
Primary
Concomitant
Myalgia Other Serious 12/1/2007 Female 159 lb 1/24/2008 France
Primary
Secondary
Concomitant
Intestinal Perforation Other Serious 1/16/2008 Female 240 lb 2/4/2008 Physician United States
Primary
Concomitant
Hypotension Life Threatening 7/18/2007 47 Female 126 lb 2/6/2008 Physician United States
Primary
Secondary
Concomitant
Polymyalgia Rheumatica Other Serious 8/1/2007 Female 2/18/2008 Other Health Professional France
Primary
Secondary
Weight Bearing Difficulty Hospitalization 1/13/2008 51 Male 220 lb 2/6/2008 United States
Primary
Secondary
Concomitant
Delirium Other Serious 65 Male 2/20/2008 Other Health Professional India
Primary
Concomitant
Drug Interaction Life Threatening 10/7/2007 74 Female 2/27/2008 Other Health Professional Germany
Primary
Concomitant
Interacting
Memory Impairment Other Serious 65 Male 3/6/2008
Primary
Concomitant
Myopathy Hospitalization 7/1/2007 Female 3/9/2008 Physician Australia
Primary
Secondary
Concomitant
Vaginal Discharge 2/1/2008 Female 117 lb 6/12/2008 Consumer United States
Primary
Concomitant
Flushing 6/15/2008 Female 250 lb 8/29/2008 United States
Primary
Concomitant
Dehydration Hospitalization 8/20/2008 Female 199 lb 9/10/2008 Consumer United States
Primary
Secondary
Concomitant
Accidental Exposure 8/14/2008 Female 9/13/2008 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2006 Female 102 lb 9/15/2008 United States
Primary
Concomitant
Urine Output Decreased Other Serious 5/1/2006 49 Female 12/31/2008 Lawyer United States
Primary
Concomitant
Retching Other Serious 11/12/2008 Female 1/5/2009 Consumer United States
Primary
Secondary
Concomitant
Troponin Increased Other Serious 1/1/2003 78 Male 140 lb 1/8/2009 United States
Primary
Concomitant
Rhabdomyolysis Other Serious 5/1/2008 1/23/2009 France
Primary
Concomitant
Interacting
Tremor Hospitalization 11/1/2008 57 Female 147 lb 1/26/2009 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Cryptococcal Hospitalization 11/22/2008 Male 220 lb 2/9/2009 United States
Primary
Secondary
Concomitant
Somnambulism Other Serious 8/5/2008 50 Female 196 lb 1/23/2009 Physician United States
Primary
Concomitant
Infection Hospitalization 8/1/2008 18 Female 101 lb 2/13/2009 Consumer Brazil
Primary
Concomitant
Urine Output Decreased Other Serious 5/1/2006 49 Female 2/18/2009 Lawyer United States
Primary
Concomitant
Intestinal Stenosis Hospitalization 8/1/2008 18 Female 101 lb 2/27/2009 Consumer Brazil
Primary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 3/2/2009 Consumer United States
Primary
Secondary
Concomitant
Intestinal Stenosis Hospitalization 8/1/2008 18 Female 101 lb 3/10/2009 Consumer Brazil
Primary
Concomitant
Agranulocytosis Other Serious 2/2/2009 3/20/2009 Other Health Professional France
Primary
Secondary
Concomitant
Hepatic Encephalopathy Hospitalization 4/1/2009 77 5/26/2009 Physician Italy
Primary
Concomitant
Hepatic Encephalopathy Hospitalization 4/1/2009 77 6/5/2009 Physician Italy
Primary
Concomitant
Vision Blurred Hospitalization 59 Female 10/10/2009 United States
Primary
Concomitant
Atrial Fibrillation Other Serious 70 Male 10/23/2009 Physician United States
Primary
Secondary
Vision Blurred Other Serious 59 Female 10/26/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 75 Female 10/26/2009 Lawyer United States
Primary
Concomitant
Ulcerative Keratitis Other Serious 4/6/2009 54 Female 10/30/2009 Sweden
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 70 Male 11/5/2009 Physician United States
Primary
Secondary
Therapeutic Agent Toxicity Other Serious 59 Female 11/2/2009 United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 11/12/2008 Female 11/10/2009 Consumer United States
Primary
Secondary
Concomitant
Peritonitis Bacterial Other Serious 10/9/2009 58 Female 11/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 75 Female 11/9/2009 United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 11/12/2008 Female 11/24/2009 Consumer United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 56 Female 11/18/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 75 Female 11/17/2009 United States
Primary
Concomitant
Vomiting Hospitalization 79 Female 11/17/2009 United States
Primary
Concomitant
Thalassaemia Other Serious 76 Female 11/17/2009 United States
Primary
Concomitant
Weight Increased Other Serious 11/1/2008 36 Male 11/19/2009 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 75 Female 11/24/2009 Lawyer United States
Primary
Concomitant
Tachycardia Other Serious 1/31/2008 76 Male 159 lb 12/1/2009 Physician Austria
Primary
Concomitant
Skin Disorder Life Threatening 1/1/2008 Female 292 lb 12/1/2009 Consumer United States
Primary
Concomitant
Sepsis Life Threatening 11/21/2009 Male 161 lb 12/16/2009 Physician India
Primary
Secondary
Concomitant
Fatigue Other Serious 1/30/2009 Female 129 lb 12/21/2009 Physician United States
Primary
Secondary
Concomitant
Fatigue Other Serious 1/30/2009 Female 129 lb 12/22/2009 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 11/1/2009 Female 12/22/2009 Consumer United States
Primary
Concomitant
Sepsis Life Threatening 11/21/2009 Male 161 lb 12/23/2009 Physician India
Primary
Secondary
Concomitant
Sepsis Life Threatening 11/21/2009 Male 161 lb 12/24/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 11/21/2009 Male 161 lb 12/28/2009 Physician India
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 9/1/2006 Female 139 lb 12/28/2009 Physician United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 11/21/2009 Male 161 lb 12/29/2009 Physician India
Primary
Secondary
Concomitant
Sepsis Life Threatening 11/21/2009 Male 161 lb 12/30/2009 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 11/21/2009 Male 161 lb 12/31/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 3/16/2006 56 Female 88 lb 12/31/2009 Physician Korea, Republic Of
Primary
Concomitant
Urinary Tract Infection Hospitalization 9/1/2006 Female 139 lb 1/6/2010 Physician United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 11/21/2009 Male 161 lb 1/6/2010 Physician India
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 75 Female 1/13/2010 Lawyer United States
Primary
Concomitant
Rash Other Serious 2/1/2008 84 Female 1/27/2010 Lawyer United States
Primary
Concomitant
Pulmonary Oedema Life Threatening 3/4/2005 66 Male 158 lb 2/12/2010 Physician Belgium
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 3/4/2005 66 Male 159 lb 2/15/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Stress Cardiomyopathy Life Threatening 3/4/2005 66 Male 158 lb 2/18/2010 Physician Belgium
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/30/2009 Male 2/19/2010 Consumer United States
Primary
Secondary
Concomitant
Surgery Hospitalization 67 Female 2/5/2010 United States
Primary
Concomitant
Vomiting Other Serious 1/1/2007 53 Female 146 lb 2/24/2010 Other Health Professional United States
Primary
Concomitant
Nausea Hospitalization 67 Female 2/5/2010 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/6/2010 76 Female 2/26/2010 Other Health Professional United States
Primary
Secondary
Rash Generalised Other Serious 2/1/2008 83 Female 137 lb 2/26/2010 Other Health Professional United States
Primary
Concomitant
Wegener's Granulomatosis Other Serious 1/1/2007 59 Male 216 lb 3/3/2010 United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 Male 3/4/2010 Lawyer United States
Primary
Concomitant
Pain Hospitalization 12/16/2009 76 Female 3/17/2010 Other Health Professional Denmark
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 12/16/2009 76 Female 3/26/2010 United States
Primary
Secondary
Weight Decreased Other Serious 11/21/2009 74 Male 161 lb 4/1/2010 Physician India
Primary
Secondary
Concomitant
Pancreatitis Relapsing Hospitalization 2/6/2010 22 Female 124 lb 3/30/2010 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 12/12/2009 59 Female 77 lb 3/30/2010 Pharmacist United States
Primary
Concomitant
Sepsis Life Threatening 11/21/2009 74 Male 161 lb 4/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 11/21/2009 74 Male 161 lb 4/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 11/21/2009 74 Male 161 lb 4/12/2010 Physician India
Primary
Secondary
Concomitant
Sepsis Life Threatening 11/21/2009 74 Male 161 lb 4/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Other Serious 1/1/2008 47 Female 4/16/2010 Consumer Brazil
Primary
Concomitant
Vomiting Other Serious 1/1/2007 53 Female 146 lb 4/16/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 75 Female 4/13/2010 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/6/2010 76 Female 4/29/2010 Other Health Professional United States
Primary
Secondary
Sepsis Life Threatening 11/21/2009 74 Male 161 lb 5/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 11/21/2009 74 Male 161 lb 5/20/2010 Physician India
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 1/1/1996 44 Male 5/24/2010 Other Health Professional United States
Primary
Concomitant
Haemorrhage Intracranial Other Serious 2/1/2008 77 Female 5/25/2010 Lawyer United States
Primary
Concomitant
Angina Unstable Hospitalization 3/6/2010 70 Female 190 lb 5/28/2010 Physician United States
Primary
Concomitant
Limb Discomfort Hospitalization Female 6/2/2010 Physician United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 6/3/2010 Other Health Professional United States
Primary
Concomitant
Orthostatic Hypotension Hospitalization Female 6/3/2010 Physician United States
Primary
Secondary
Concomitant
Ventricular Hypokinesia Hospitalization 66 Female 6/4/2010 United States
Primary
Concomitant
Weight Increased Other Serious 11/1/2009 74 Male 368 lb 6/18/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 75 Female 6/11/2010 Lawyer United States
Primary
Concomitant
International Normalised Ratio Decreased Hospitalization 3/1/2007 83 Female 200 lb 6/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Headache Male 6/29/2010 Consumer United States
Primary
Interacting
Laboratory Test Abnormal Female 6/30/2010 Other Health Professional United States
Primary
Concomitant
Angina Unstable Hospitalization 3/6/2010 70 Female 190 lb 7/12/2010 Physician United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 12/1/2007 53 Female 7/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Required Intervention 7/1/2010 67 Male 253 lb 7/14/2010 Pharmacist United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 7/21/2010 Other Health Professional United States
Primary
Concomitant
Lethargy Other Serious 2/10/2008 77 Female 7/22/2010 Lawyer United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 7/25/2007 50 Male 7/27/2010 Physician India
Primary
Secondary
Concomitant
Tremor 7/14/2010 83 Female 7/28/2010 Consumer
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 6/16/2009 73 Male 154 lb 8/5/2010 Consumer Canada
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Other Serious 1/1/2008 71 Female 160 lb 8/5/2010 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 12/30/2009 82 Female 117 lb 7/1/2010 Pharmacist United States
Primary
Concomitant
Sepsis Life Threatening 11/21/2009 74 Male 161 lb 8/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 11/21/2009 74 Male 161 lb 8/26/2010 Physician India
Primary
Secondary
Concomitant
Weight Decreased Life Threatening 11/21/2009 74 Male 161 lb 8/27/2010 Physician India
Primary
Secondary
Concomitant
Sepsis Life Threatening 11/21/2009 74 Male 161 lb 9/2/2010 Physician India
Primary
Secondary
Concomitant
Swollen Tongue Other Serious 1/1/2010 71 Female 213 lb 9/2/2010 Consumer United States
Primary
Secondary
Concomitant
Lung Disorder 8/1/2010 68 Female 9/9/2010 Consumer
Primary
Concomitant
Swollen Tongue Other Serious 1/1/2010 71 Female 213 lb 9/16/2010 Consumer United States
Primary
Secondary
Concomitant
Drug Ineffective 73 Female 9/18/2010 Physician United States
Primary
Concomitant
Dermatitis Exfoliative Other Serious 5/21/2010 59 Male 163 lb 9/28/2010 Physician Netherlands
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2008 71 Female 160 lb 10/7/2010 Consumer United States
Primary
Concomitant
Pain 10/1/2009 Female 10/13/2010 Physician United States
Primary
Concomitant
Metastases To Bone Other Serious 2/10/2008 77 Female 10/15/2010 Lawyer United States
Primary
Concomitant
Dermatitis Exfoliative Other Serious 5/21/2010 59 Male 163 lb 10/20/2010 Physician Netherlands
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 10/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 11/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 64 Male 207 lb 11/5/2010 Physician Australia
Primary
Concomitant
Death Death 8/27/2010 88 Female 11/8/2010 Physician Portugal
Primary
Concomitant
Hunger Other Serious 44 Female 11/3/2010 Consumer United States
Primary
Concomitant
Pulmonary Oedema Other Serious 84 Male 11/19/2010 Lawyer United States
Primary
Concomitant
Weight Increased Other Serious 8/1/2010 52 Female 128 lb 11/23/2010 Consumer Brazil
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 2/21/2008 69 Female 150 lb 12/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Nipple Pain Female 11/26/2010 Consumer United States
Primary
Concomitant
Wegener's Granulomatosis Other Serious 1/1/2007 59 Male 216 lb 12/2/2010 Lawyer United States
Primary
Concomitant
Ventricular Extrasystoles Other Serious 1/1/2008 12/2/2010 Lawyer United States
Primary
Concomitant
Weight Increased 10/1/2010 63 Female 140 lb 12/3/2010 Consumer United States
Primary
Concomitant
Convulsion Other Serious Male 10/11/2010 United States
Primary
Concomitant
Psoriasis Other Serious 9/24/2010 12/15/2010 United States
Primary
Concomitant
Urticaria 1/1/2010 24 Female 113 lb 11/6/2010 Consumer United States
Primary
Concomitant

Drug Data