Metformin Hydrochloride combined with Pantoprazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hyponatraemia Hospitalization 10/1/2005 80 Female 148 lb 1/9/2006 Other Health Professional France
Primary
Secondary
Concomitant
Syncope Other Serious 7/26/2005 Male 2/3/2006 Puerto Rico
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/9/2006 United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/9/2006 United States
Primary
Concomitant
Pleural Effusion Other Serious 7/26/2005 Male 215 lb 2/16/2006 Puerto Rico
Primary
Concomitant
Weight Decreased Hospitalization 3/1/2005 79 Male 216 lb 2/23/2006 Physician Italy
Primary
Concomitant
Haemoptysis Other Serious 2/26/2006 72 Male 224 lb 3/28/2006 Consumer United Kingdom
Primary
Concomitant
Thrombosis Other Serious 66 Male 3/20/2006 Pharmacist Germany
Primary
Concomitant
Thrombocytopenia Other Serious 7/26/2005 Male 215 lb 4/7/2006 Puerto Rico
Primary
Concomitant
Death Death 3/29/2006 67 Female 6/14/2006 Other Health Professional Denmark
Primary
Concomitant
Death Death 3/29/2006 67 Female 6/28/2006 Other Health Professional Denmark
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 11/16/2007 75 Male 2/15/2008 Physician Australia
Primary
Secondary
Concomitant
Rash Generalised 11/28/2007 Male 208 lb 8/27/2008 Consumer United States
Primary
Secondary
Concomitant
Flushing Male 2/24/2009 United States
Primary
Secondary
Concomitant
Urine Colour Abnormal Other Serious 7/1/2008 Male 250 lb 7/2/2009 Consumer United States
Primary
Concomitant
Stent Placement Hospitalization 1/1/2008 Male 172 lb 8/5/2009 Consumer United States
Primary
Concomitant
Stent Placement Other Serious 1/1/2008 Male 172 lb 8/14/2009 Consumer United States
Primary
Concomitant
Stent Placement Other Serious 1/1/2008 Male 172 lb 10/1/2009 Consumer United States
Primary
Concomitant
Cerebral Ischaemia Disability 10/28/2009 69 Male 192 lb 11/9/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 4/26/2006 Female 117 lb 11/30/2009 Physician Ireland
Primary
Concomitant
Cerebral Ischaemia Disability 10/28/2009 69 Male 192 lb 12/3/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Cerebral Ischaemia Hospitalization 10/28/2009 69 12/22/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 9/1/2006 Female 139 lb 1/6/2010 Physician United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2009 Female 161 lb 1/12/2010 Physician Austria
Primary
Concomitant
Muscular Weakness Other Serious 10/6/2009 Female 1/21/2010 Physician Germany
Primary
Concomitant
Cerebral Ischaemia Hospitalization 10/28/2009 69 Male 192 lb 1/25/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Visual Acuity Reduced Required Intervention 80 Female 1/28/2010 Netherlands
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 8/1/2009 Female 2/18/2010 Physician Canada
Primary
Concomitant
Thrombocytopenia Life Threatening 8/1/2009 Female 2/18/2010 Physician Canada
Primary
Secondary
Concomitant
Retching Other Serious 12/22/2009 Male 2/18/2010 Physician Brazil
Primary
Secondary
Concomitant
Portal Hypertensive Gastropathy Hospitalization 2/17/2010 Male 123 lb 3/1/2010 Physician Taiwan, Province Of China
Primary
Concomitant
Ventricular Fibrillation Other Serious 12/4/2007 71 Female 121 lb 3/3/2010 Lawyer United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 10/1/2007 61 Male 214 lb 3/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 11/1/2007 58 Male 137 lb 3/4/2010 Lawyer United States
Primary
Concomitant
Swelling Face Life Threatening 11/19/2009 Male 266 lb 3/18/2010 Physician United States
Primary
Secondary
Concomitant
Cerebral Ischaemia Hospitalization 10/28/2009 69 Male 192 lb 3/30/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/7/2007 49 Male 4/28/2010 United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/5/2010 54 Male 199 lb 5/14/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 4/8/2008 68 Male 5/14/2010 Lawyer United States
Primary
Concomitant
Weight Increased Hospitalization 1/7/2007 49 Male 5/11/2010 United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 76 Male 5/18/2010 United States
Primary
Concomitant
Urine Albumin/creatinine Ratio Other Serious 3/11/2010 50 Male 5/27/2010 Physician Canada
Primary
Concomitant
Ventricular Tachycardia Other Serious 11/1/2007 58 Male 137 lb 5/28/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 2/16/2010 71 Male 6/21/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 2/16/2010 71 Male 7/5/2010 Physician United States
Primary
Concomitant
Stent Placement Other Serious 1/1/2008 75 Male 172 lb 9/16/2010 Consumer United States
Primary
Concomitant
Procedural Complication Hospitalization 11/6/2009 71 Female 180 lb 9/15/2010 Consumer United States
Primary
Secondary
Concomitant
Vasculitis Other Serious 10/29/2007 63 Male 262 lb 12/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Venous Occlusion Hospitalization 11/1/2010 69 Female 159 lb 12/3/2010 Consumer Brazil
Primary
Secondary
Concomitant
Injection Site Abscess Other Serious 9/7/2010 48 Male 284 lb 12/10/2010 Other Health Professional United States
Primary
Concomitant
Stent Placement Other Serious 1/1/2008 75 Male 172 lb 10/1/2009 Consumer United States
Primary
Concomitant
Cerebral Ischaemia Hospitalization 10/28/2009 69 12/22/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Vasculitis Other Serious 10/29/2007 63 Male 262 lb 12/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 6/12/2010 56 Male 141 lb 1/7/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Haemorrhage Other Serious 1/1/2008 68 Female 240 lb 1/21/2011 United States
Primary
Concomitant
Death Death 2/5/2011 77 Female 227 lb 2/11/2011 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2010 70 Male 2/17/2011 Consumer Brazil
Primary
Concomitant
Cytolytic Hepatitis Other Serious 1/6/2011 76 Male 2/28/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Weight Increased Hospitalization Female 154 lb 2/28/2011 Consumer Brazil
Primary
Concomitant
Oral Herpes Other Serious 62 Female 3/24/2011 Physician United States
Primary
Concomitant
Emotional Disorder Hospitalization 1/1/2009 69 Male 282 lb 7/21/2011 Consumer Brazil
Primary
Secondary
Concomitant
Impaired Healing Hospitalization 8/4/2011 58 Male 295 lb 8/22/2011 Physician Germany
Primary
Secondary
Concomitant
Agitation Hospitalization 8/11/2011 88 Male 192 lb 8/29/2011 Consumer Brazil
Primary
Secondary
Concomitant
Anxiety Hospitalization 8/16/2011 Male 201 lb 8/30/2011 Other Health Professional Germany
Primary
Concomitant
Long Qt Syndrome Hospitalization 4/1/2011 82 Female 8/30/2011 Physician Germany
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 5/9/2008 69 Female 9/2/2011 Lawyer United States
Primary
Concomitant
Psoriasis Hospitalization 6/30/2011 70 Male 165 lb 9/15/2011 Physician Germany
Primary
Secondary
Concomitant
Sinusitis Other Serious 1/1/2010 56 Female 192 lb 9/21/2011 Physician Brazil
Primary
Concomitant
Electrolyte Imbalance Hospitalization 6/9/2011 Female 187 lb 10/10/2011 Physician Denmark
Primary
Concomitant
Multiple Sclerosis Relapse Hospitalization 5/2/2011 53 Female 203 lb 10/11/2011 Other Health Professional United States
Primary
Concomitant
Gastric Cancer Other Serious Female 10/11/2011 Physician Portugal
Primary
Concomitant
Wound Infection Hospitalization 8/4/2011 58 Male 280 lb 10/12/2011 Physician Germany
Primary
Secondary
Concomitant
Osteomyelitis Acute Hospitalization 10/13/2011 Physician Switzerland
Primary
Secondary
Concomitant
Myocardial Ischaemia Hospitalization 72 Female 176 lb 10/13/2011 Physician Brazil
Primary
Secondary
Concomitant
Anaemia Other Serious 11/1/2007 58 Male 137 lb 10/17/2011 Lawyer United States
Primary
Secondary
Concomitant
Pulmonary Function Test Decreased 5/1/2011 67 Male 220 lb 10/18/2011 United States
Primary
Concomitant
Memory Impairment Hospitalization 5/3/2011 59 Male 152 lb 10/31/2011 Physician Netherlands
Primary
Concomitant
Rheumatoid Arthritis Hospitalization Female 152 lb 11/1/2011 Consumer Brazil
Primary
Concomitant
Dyspnoea Hospitalization 72 Female 176 lb 12/15/2011 Physician Brazil
Primary
Secondary
Concomitant
Pneumonia Death 73 Male 236 lb 12/21/2011 Germany
Primary
Concomitant
Arthralgia Hospitalization 10/1/2011 70 Female 154 lb 1/20/2012 Consumer Brazil
Primary
Concomitant
Cerebral Ischaemia Disability 10/28/2009 69 Male 192 lb 2/1/2012 Physician Canada
Primary
Secondary
Concomitant
Failure To Thrive Hospitalization 11/26/2011 69 Female 144 lb 2/10/2012 Physician United States
Primary
Secondary
Concomitant
Genital Disorder Male Hospitalization 1/1/2011 50 Male 2/17/2012 Consumer Brazil
Primary
Concomitant
Secretion Discharge Hospitalization 4/1/2011 68 Male 185 lb 2/27/2012 Physician Germany
Primary
Concomitant
Arthritis Disability 1/1/2009 63 Female 3/1/2012 Lawyer United States
Primary
Concomitant
Osteomyelitis Acute Other Serious 68 Female 3/8/2012 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Somnolence Other Serious 10/21/2010 58 Female 3/16/2012 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 2/14/2012 44 Female 150 lb 3/19/2012 Germany
Primary
Concomitant
Hepatic Enzyme Increased Hospitalization 12/23/2011 79 Female 3/19/2012 Other Health Professional Germany
Primary
Secondary
Concomitant
Hallucination, Visual Life Threatening 11/21/2011 70 Male 3/20/2012 Other Health Professional Germany
Primary
Secondary
Concomitant
Insomnia Life Threatening 11/21/2011 70 Male 3/20/2012 Other Health Professional Germany
Primary
Secondary
Concomitant
Restlessness Hospitalization 71 Female 4/3/2012 Consumer Denmark
Primary
Concomitant
Suicide Attempt Other Serious 4/10/2012 22 Female 4/19/2012 Physician Germany
Primary
Secondary
Rectal Haemorrhage Other Serious 1/1/2007 58 Male 174 lb 5/8/2012 Consumer Brazil
Primary
Secondary
Concomitant
Acute Myocardial Infarction Life Threatening 4/26/2012 62 Male 5/25/2012 Physician Canada
Primary
Concomitant
Decreased Appetite Disability 2/16/2012 48 Female 163 lb 6/5/2012 Consumer Venezuela
Primary
Concomitant
Transaminases Increased Other Serious 2/16/2012 48 Female 163 lb 6/21/2012 Consumer Venezuela
Primary
Concomitant
Tardive Dyskinesia Hospitalization 1/1/2010 71 Female 6/29/2012 Other Health Professional France
Primary
Secondary
Concomitant
Tardive Dyskinesia Disability 1/1/2010 71 Female 7/5/2012 Other Health Professional France
Primary
Secondary
Concomitant
Feeling Hot Hospitalization 12/16/2011 66 Female 7/13/2012 Physician Switzerland
Primary
Concomitant
C-reactive Protein Increased Other Serious 5/1/2012 Female 7/16/2012 Physician Germany
Primary
Concomitant
Economic Problem Other Serious Female 7/3/2012 Lawyer United States
Primary
Concomitant
Respiratory Syncytial Virus Infection Death 3/22/2012 61 Male 245 lb 7/18/2012 Other Health Professional Germany
Primary
Secondary
Concomitant
Chest Pain Hospitalization 4/1/2010 7/18/2012 Physician United States
Primary
Secondary
Concomitant
Blood Pressure Decreased Hospitalization 1/29/2012 77 Female 165 lb 7/19/2012 Physician Germany
Primary
Concomitant
Hepatic Encephalopathy Hospitalization 6/29/2010 70 Male 176 lb 7/23/2012 Consumer Germany
Primary
Concomitant
Adenocarcinoma Other Serious 4/24/2006 73 Male 7/23/2012 Physician Ireland
Primary
Secondary
Concomitant
Ovarian Cancer Death 6/6/2011 63 Female 7/25/2012 Other Health Professional Australia
Primary
Concomitant
Dementia Other Serious 68 Female 7/26/2012 Consumer United States
Primary
Concomitant
Haemoglobin Decreased Hospitalization 2/23/2011 57 Female 141 lb 7/27/2012 Physician Netherlands
Primary
Concomitant
Angioedema Other Serious 7/27/2012 Consumer Germany
Primary
Secondary
Injury Hospitalization 5/1/2008 50 Female 7/27/2012 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Life Threatening 3/30/2012 88 Female 7/30/2012 Other Health Professional United Kingdom
Primary
Concomitant
Intervertebral Disc Protrusion Other Serious 6/1/2012 78 Female 7/30/2012 Consumer Brazil
Primary
Concomitant
Death Life Threatening 3/1/2012 66 Male 176 lb 7/31/2012 Physician Germany
Primary
Concomitant
Angioedema Other Serious 7/31/2012 Consumer United States
Primary
Secondary
Angioedema Other Serious 7/31/2012 Other Health Professional United States
Primary
Secondary
Suicide Attempt Hospitalization 12/25/2011 8/1/2012 Consumer United States
Primary
Secondary
Concomitant
Impaired Healing Other Serious 5/16/2012 63 Male 258 lb 8/1/2012 Physician Germany
Primary
Concomitant
Fracture Delayed Union Other Serious 6/29/2012 72 Female 165 lb 8/1/2012 Consumer Canada
Primary
Concomitant
Off Label Use 6/15/2012 32 Male 255 lb 8/2/2012 Consumer United States
Primary
Concomitant
Angioedema Other Serious 8/2/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Diabetes Mellitus 10/1/2011 56 Male 205 lb 8/3/2012 Consumer United States
Primary
Concomitant
Flushing Male 190 lb 8/3/2012 Consumer United States
Primary
Concomitant
Blood Glucose Increased 4/17/2012 64 Female 150 lb 8/3/2012 Consumer United States
Primary
Concomitant
Abdominal Pain Upper Female 8/3/2012 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 2/23/2011 57 Female 141 lb 8/8/2012 Physician Netherlands
Primary
Concomitant
Hypoglycaemia Hospitalization 12/25/2011 8/7/2012 Consumer Germany
Primary
Secondary
Concomitant
Hip Fracture Hospitalization 5/20/2011 72 Female 8/9/2012 Other Health Professional United States
Primary
Concomitant
Haemoglobin Decreased Other Serious 5/27/2012 65 Male 8/9/2012 Physician Canada
Primary
Concomitant
Angioedema Hospitalization 8/8/2012 Other Health Professional United States
Primary
Secondary
Staphylococcal Osteomyelitis Death 4/1/2011 68 Male 185 lb 8/10/2012 Physician Germany
Primary
Concomitant
Blood Cholesterol Abnormal Hospitalization 7/1/2010 68 Female 8/13/2012 Consumer Mexico
Primary
Secondary
Concomitant
Rales Hospitalization 5/31/2011 79 Female 8/14/2012 Consumer Australia
Primary
Concomitant
Mental Status Changes Hospitalization 6/1/2012 63 Male 227 lb 8/15/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Other Serious 5/27/2012 65 Male 8/15/2012 Physician Canada
Primary
Concomitant
Vomiting Hospitalization 4/14/2011 8/16/2012 Other Health Professional Germany
Primary
Concomitant
Bacterial Infection Hospitalization 8/10/2012 85 Female 162 lb 8/17/2012 Other Health Professional Canada
Primary
Concomitant
Cholecystitis Hospitalization 11/24/2011 63 Female 193 lb 8/27/2012 Physician Switzerland
Primary
Secondary
Concomitant
Sudden Death Death 2/6/2012 68 Female 10/12/2012 Physician At
Primary
Concomitant
Angioedema Other Serious 11/5/2011 71 Female 8/20/2012 Other Health Professional Country Not Specified
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 2012 74 Male 196 lb 10/20/2012 Physician Us
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 8/22/2012 67 Male 10/16/2012 Consumer Us
Primary
Concomitant
Off Label Use 2005 60 Female 139 lb 12/4/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Hip Surgery Hospitalization 11/26/2012 60 Female 141 lb 10/18/2013 Consumer Ca
Primary
Secondary
Concomitant
Vision Blurred 10/2012 70 Female 1/29/2013 Other Health Professional Dk
Primary
Concomitant
Nausea Other Serious 79 Female 3/21/2013 Other Health Professional Au
Primary
Concomitant
Hypertension Other Serious 10/2013 80 Female 229 lb 11/1/2013 Consumer Us
Primary
Secondary
Vomiting Hospitalization 7/7/2011 45 Male 7/10/2013 Physician Country Not Specified
Primary
Secondary
Concomitant

Drug Data