Pantoprazole combined with Xarelto

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Deep Vein Thrombosis Other Serious 8/15/2010 62 Male 196 lb 2/9/2011 Other Health Professional France
Primary
Secondary
Concomitant
Angina Pectoris Life Threatening 10/7/2010 72 Male 198 lb 6/8/2011 Other Health Professional Germany
Primary
Concomitant
Interacting
Electrocardiogram St Segment Depression Life Threatening 10/7/2010 72 Male 6/20/2011 Other Health Professional Germany
Primary
Concomitant
Interacting
Cholecystitis Hospitalization 8/6/2009 57 Male 132 lb 8/15/2011 Physician Germany
Primary
Concomitant
Haemarthrosis Hospitalization 12/8/2009 83 Male 9/13/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Post Procedural Haemorrhage Hospitalization 12/8/2009 83 Male 161 lb 9/14/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Liver Abscess Hospitalization 78 Male 165 lb 9/14/2011 Other Health Professional Canada
Primary
Concomitant
Pulmonary Embolism Hospitalization 9/10/2011 67 Male 260 lb 9/20/2011 Pharmacist Canada
Primary
Concomitant
Bronchopneumonia Other Serious 2/18/2011 69 Male 194 lb 9/30/2011 Physician Switzerland
Primary
Concomitant
Interacting
Thrombocytosis Life Threatening 10/26/2010 70 Female 148 lb 10/27/2011 Physician Switzerland
Primary
Concomitant
Hyponatraemia Hospitalization 84 Female 11/30/2011 Other Health Professional United Kingdom
Primary
Concomitant
Drug Interaction Hospitalization 10/18/2011 62 Male 12/5/2011 Physician France
Primary
Concomitant
Interacting
Dyspnoea Other Serious 12/4/2011 68 Male 290 lb 12/16/2011 Consumer United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 10/31/2011 74 Female 139 lb 1/30/2012 Physician Slovenia
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 10/8/2011 79 Male 2/2/2012 Other Health Professional France
Primary
Concomitant
Impaired Healing Other Serious 11/21/2011 74 Male 243 lb 2/2/2012 Physician Germany
Primary
Concomitant
Drug Prescribing Error Other Serious 12/4/2011 68 Male 290 lb 2/2/2012 Consumer United States
Primary
Concomitant
Fall Hospitalization 10/4/2011 79 Male 2/7/2012 Other Health Professional France
Primary
Concomitant
Pulmonary Embolism Disability 1/19/2012 74 Female 2/17/2012 Physician Germany
Primary
Concomitant
Venous Thrombosis Limb Other Serious 2/14/2012 59 Female 165 lb 2/24/2012 Physician Germany
Primary
Concomitant
Thrombocytosis Other Serious Female 168 lb 2/24/2012 Physician Germany
Primary
Concomitant
Platelet Count Decreased Other Serious 64 Female 2/24/2012 Other Health Professional Canada
Primary
Concomitant
Pulmonary Embolism Other Serious 67 Male 2/24/2012 Other Health Professional Canada
Primary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 2/13/2012 54 Female 165 lb 2/28/2012 Physician Germany
Primary
Concomitant
Thrombosis Hospitalization 8/30/2011 64 Male 214 lb 3/2/2012 Consumer Germany
Primary
Concomitant
Cerebrovascular Accident Life Threatening 2/17/2012 82 Male 214 lb 3/5/2012 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Embolism Disability 1/19/2012 74 Female 3/7/2012 Physician Germany
Primary
Concomitant
Haematoma Other Serious 8/30/2011 64 Male 214 lb 3/9/2012 Consumer Germany
Primary
Concomitant
Renal Impairment Life Threatening 2/5/2012 65 Male 234 lb 3/9/2012 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Cerebrovascular Accident Life Threatening 2/17/2012 82 Male 214 lb 3/12/2012 Physician Germany
Primary
Secondary
Concomitant
Haematoma Hospitalization 8/30/2011 64 Male 214 lb 3/15/2012 Consumer Germany
Primary
Concomitant
Aphasia Other Serious 2/20/2012 74 Female 165 lb 3/15/2012 Physician Germany
Primary
Concomitant
Cerebral Haemorrhage Hospitalization 2/17/2012 82 Male 214 lb 3/20/2012 Physician Germany
Primary
Concomitant
Interacting
Pyelonephritis Hospitalization 2/20/2012 80 Female 152 lb 3/22/2012 Physician Germany
Primary
Concomitant
Mouth Haemorrhage Other Serious 2/17/2012 82 Male 214 lb 3/26/2012 Physician Germany
Primary
Secondary
Concomitant
Hepatic Encephalopathy Hospitalization 12/19/2011 48 Female 185 lb 3/30/2012 Physician Germany
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 11/9/2011 67 Male 4/4/2012 Other Health Professional Germany
Primary
Concomitant
Hepatic Lesion Other Serious 11/9/2011 67 Male 4/6/2012 Other Health Professional Germany
Primary
Concomitant
Pulmonary Embolism Other Serious 67 Male 260 lb 4/6/2012 Other Health Professional Canada
Primary
Concomitant
Platelet Count Decreased Hospitalization 9/28/2011 64 Female 126 lb 4/10/2012 Pharmacist Canada
Primary
Concomitant
Frequent Bowel Movements Hospitalization 3/9/2012 70 Female 4/12/2012 Other Health Professional Netherlands
Primary
Concomitant
Coagulopathy Hospitalization 12/19/2011 48 Female 185 lb 4/12/2012 Physician Germany
Primary
Concomitant
Tooth Discolouration Hospitalization 2/22/2012 91 Female 161 lb 4/17/2012 Physician Germany
Primary
Concomitant
Cerebral Haemorrhage Life Threatening 11/2/2011 77 Male 183 lb 4/23/2012 Other Health Professional Germany
Primary
Secondary
Concomitant
Cerebral Haemorrhage Life Threatening 11/2/2011 4/24/2012 Physician Germany
Primary
Secondary
Concomitant
Gastric Haemorrhage Hospitalization 4/14/2012 77 Female 4/27/2012 Other Health Professional Finland
Primary
Concomitant
Cerebral Haemorrhage Life Threatening 11/2/2011 77 Male 183 lb 5/3/2012 Other Health Professional Germany
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 2/14/2012 78 Female 132 lb 5/4/2012 Physician Germany
Primary
Concomitant
Oedema Peripheral Hospitalization 1/20/2012 78 Female 150 lb 5/7/2012 Physician Germany
Primary
Concomitant
Nausea Hospitalization Female 148 lb 5/8/2012 Physician Germany
Primary
Concomitant
Liver Function Test Abnormal Life Threatening 2/14/2012 89 Female 148 lb 5/10/2012 Physician Germany
Primary
Concomitant
Diarrhoea Death 12/1/2011 82 Male 176 lb 5/11/2012 Physician Switzerland
Primary
Secondary
Concomitant
Interacting
Renal Function Test Abnormal Death 12/27/2011 82 Male 176 lb 5/11/2012 Pharmacist Switzerland
Primary
Secondary
Concomitant
Interacting
Hyperbilirubinaemia Death 12/1/2011 82 Male 176 lb 5/14/2012 Pharmacist Switzerland
Primary
Secondary
Concomitant
Interacting
Arthritis Hospitalization 1/24/2012 81 Female 5/14/2012 Physician Switzerland
Primary
Concomitant
Thrombosis Other Serious 12/1/2011 82 Male 176 lb 5/15/2012 Physician Switzerland
Primary
Secondary
Concomitant
Interacting
Diarrhoea Hospitalization 3/16/2012 79 Female 5/16/2012 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 2/14/2012 78 Female 132 lb 5/17/2012 Physician Germany
Primary
Concomitant
Blood Alkaline Phosphatase Normal Hospitalization 2/14/2012 89 Female 148 lb 5/18/2012 Physician Germany
Primary
Concomitant
Diarrhoea Hospitalization 12/1/2011 82 Male 176 lb 5/23/2012 Pharmacist Switzerland
Primary
Secondary
Concomitant
Diarrhoea Death 12/1/2011 82 Male 176 lb 5/24/2012 Pharmacist Switzerland
Primary
Secondary
Concomitant
Anaemia Hospitalization 4/8/2012 82 Male 134 lb 5/24/2012 Pharmacist Canada
Primary
Secondary
Concomitant
Blood Alkaline Phosphatase Increased Hospitalization 12/1/2011 82 Male 176 lb 5/24/2012 Pharmacist Switzerland
Primary
Secondary
Concomitant
Anaemia Macrocytic Hospitalization 2/14/2012 78 Female 143 lb 5/24/2012 Physician Germany
Primary
Concomitant
Renal Failure Chronic Hospitalization 12/1/2011 82 Male 176 lb 5/22/2012 Pharmacist Switzerland
Primary
Secondary
Concomitant
Loss Of Consciousness Life Threatening Male 5/25/2012 Physician Germany
Primary
Secondary
Urinary Tract Infection Hospitalization 3/1/2012 89 Female 148 lb 5/29/2012 Physician Germany
Primary
Concomitant
Aspartate Aminotransferase Increased Death 12/1/2011 82 Male 176 lb 5/30/2012 Pharmacist Switzerland
Primary
Secondary
Concomitant
Lower Gastrointestinal Haemorrhage Other Serious 4/1/2012 91 Female 163 lb 6/1/2012 Physician Germany
Primary
Concomitant
Pulmonary Embolism Other Serious 9/15/2011 77 Female 129 lb 6/1/2012 Pharmacist United States
Primary
Concomitant
Jaundice Hospitalization 12/1/2011 82 Male 176 lb 5/29/2012 Pharmacist Switzerland
Primary
Secondary
Concomitant
Venous Thrombosis Other Serious Female 6/5/2012 Physician Switzerland
Primary
Concomitant
Deep Vein Thrombosis Other Serious Male 6/6/2012 Physician Switzerland
Primary
Concomitant
Deep Vein Thrombosis Other Serious 5/1/2012 69 Male 6/6/2012 Physician Switzerland
Primary
Concomitant
Pulmonary Embolism Death 5/1/2012 52 Female 229 lb 6/6/2012 Physician Netherlands
Primary
Concomitant
Gastric Ulcer Other Serious 3/21/2012 77 Male 6/6/2012 Physician Germany
Primary
Concomitant
Loss Of Consciousness Other Serious Male 6/6/2012 Physician Germany
Primary
Secondary
Venous Thrombosis Limb Hospitalization 5/2/2012 68 Male 143 lb 6/6/2012 Physician Switzerland
Primary
Concomitant
Haemorrhage Hospitalization 5/15/2012 89 Male 176 lb 6/12/2012 Pharmacist Germany
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 5/24/2012 52 Female 229 lb 6/13/2012 Pharmacist Netherlands
Primary
Concomitant
Blood Pressure Decreased Other Serious 1/1/2012 77 Female 165 lb 6/13/2012 Physician Germany
Primary
Concomitant
Tachycardia Hospitalization 4/3/2012 49 Female 6/20/2012 Physician Germany
Primary
Concomitant
Jaundice Other Serious 4/6/2012 60 Female 194 lb 6/21/2012 Physician Switzerland
Primary
Secondary
Concomitant
Haemorrhage Hospitalization 5/15/2012 89 Male 176 lb 6/22/2012 Pharmacist Germany
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/2/2009 62 Female 152 lb 6/29/2012 Physician Germany
Primary
Concomitant
Vomiting Other Serious 4/6/2012 60 Female 194 lb 7/3/2012 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Jaundice Other Serious 4/6/2012 60 Female 194 lb 7/10/2012 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 4/1/2012 91 Female 163 lb 7/12/2012 Physician Germany
Primary
Concomitant
Blood Pressure Decreased Hospitalization 1/29/2012 77 Female 165 lb 7/19/2012 Physician Germany
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 1/3/2012 67 Female 262 lb 7/23/2012 Other Health Professional Germany
Primary
Concomitant
Haemarthrosis Other Serious 5/4/2012 75 Male 238 lb 7/24/2012 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 5/24/2012 52 Female 260 lb 7/25/2012 Physician Netherlands
Primary
Concomitant
Haematoma Infection Other Serious 5/4/2012 75 Male 238 lb 7/26/2012 Physician Germany
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 1/30/2012 67 Female 183 lb 7/26/2012 Physician Germany
Primary
Concomitant
Loss Of Consciousness Life Threatening 4/15/2012 54 Male 7/31/2012 Physician Germany
Primary
Secondary
Haemoglobin Decreased Other Serious 5/27/2012 65 Male 8/9/2012 Physician Canada
Primary
Concomitant
Intestinal Ischaemia Other Serious 5/30/2012 49 Female 245 lb 8/10/2012 Physician Germany
Primary
Secondary
Concomitant
Thrombosis In Device Hospitalization 7/26/2012 76 Male 8/13/2012 Physician France
Primary
Concomitant
Menorrhagia Other Serious 6/26/2012 43 Female 141 lb 8/14/2012 Consumer Germany
Primary
Concomitant
Haemoglobin Decreased Other Serious 5/27/2012 65 Male 8/15/2012 Physician Canada
Primary
Concomitant
Ischaemic Stroke Disability 6/1/2012 78 Male 148 lb 8/16/2012 Physician Germany
Primary
Concomitant
Nausea Other Serious 5/1/2012 Female 121 lb 8/16/2012 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Circulatory Collapse Death 4/7/2012 56 Male 315 lb 8/20/2012 Other Health Professional Ireland
Primary
Concomitant
Mesenteric Artery Thrombosis Other Serious 5/30/2012 49 Female 245 lb 8/20/2012 Physician Germany
Primary
Secondary
Concomitant
Ischaemic Stroke Hospitalization 6/3/2012 72 Female 150 lb 8/22/2012 Physician Germany
Primary
Concomitant
Liver Injury Other Serious 5/1/2012 Female 121 lb 8/22/2012 Physician Switzerland
Primary
Secondary
Concomitant
Nausea Other Serious 6/13/2012 39 Female 170 lb 8/23/2012 Physician Germany
Primary
Concomitant
Cardiac Failure Hospitalization 7/26/2012 76 Male 8/23/2012 Physician France
Primary
Concomitant
Epilepsy Death 6/22/2012 81 Female 8/24/2012 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Basal Ganglia Haemorrhage Death 7/20/2012 73 Male 121 lb 11/26/2012 Physician De
Primary
Secondary
Concomitant
Interacting
Paraesthesia Other Serious 8/9/2012 63 Female 130 lb 8/28/2012 Physician De
Primary
Concomitant
Deep Vein Thrombosis Other Serious 8/22/2012 61 Male 220 lb 11/5/2012 Physician De
Primary
Concomitant
Wound Haemorrhage Other Serious 7/6/2012 78 Male 231 lb 9/7/2012 Physician De
Primary
Concomitant
Vomiting Other Serious 8/17/2012 76 Male 1/17/2013 Physician De
Primary
Secondary
Concomitant
Vomiting Disability 8/17/2012 76 Male 11/7/2012 Physician De
Primary
Secondary
Concomitant
Implant Site Haematoma Life Threatening 4/8/2012 82 Male 134 lb 11/19/2012 Other Health Professional Ca
Primary
Concomitant
Chromaturia Other Serious 9/5/2012 65 Female 132 lb 9/20/2012 Consumer Us
Primary
Concomitant
Renal Failure Acute Life Threatening Male 154 lb 9/26/2012 Other Health Professional De
Primary
Concomitant
Drug Interaction Other Serious Female 10/5/2012 Other Health Professional Us
Primary
Concomitant
Interacting
Rash Other Serious 8/29/2012 57 Male 183 lb 10/12/2012 Physician At
Primary
Concomitant
Epistaxis Hospitalization 7/2012 Male 175 lb 10/15/2012 Consumer Us
Primary
Secondary
Concomitant
International Normalised Ratio Decreased Other Serious 10/2012 Female 130 lb 10/18/2012 Consumer Us
Primary
Concomitant
Epistaxis Hospitalization Male 175 lb 10/26/2012 Consumer Us
Primary
Secondary
Concomitant
Haemangioma Hospitalization 2012 Male 11/5/2012 Physician Be
Primary
Concomitant
Puncture Site Haemorrhage Other Serious 2012 Male 170 lb 11/14/2012 Consumer Br
Primary
Secondary
Concomitant
Venous Occlusion Other Serious Male 1/3/2013 Physician De
Primary
Concomitant
Sudden Cardiac Death Death Female 11/21/2012 Physician De
Primary
Concomitant
Syncope Hospitalization 2012 Female 11/26/2012 Other Health Professional Br
Primary
Secondary
Concomitant
Insomnia Other Serious 10/2012 Male 11/26/2012 Consumer Us
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 56 Male 12/13/2012 Physician Fi
Primary
Concomitant
Pulmonary Embolism Other Serious 2012 Female 12/6/2012 Other Health Professional Br
Primary
Secondary
Concomitant
Monarthritis Hospitalization 7/11/2012 66 Male 198 lb 2/5/2013 Physician De
Primary
Concomitant
Haemorrhage Intracranial Hospitalization 10/22/2012 84 Male 196 lb 12/28/2012 Physician De
Primary
Secondary
Concomitant
Melaena Hospitalization 10/2012 Female 271 lb 12/19/2012 Physician Us
Primary
Concomitant
Haemolytic Anaemia Hospitalization Male 161 lb 12/23/2012 Physician De
Primary
Concomitant
Cerebrovascular Accident Death 8/27/2012 91 Male 187 lb 2/20/2013 Physician De
Primary
Concomitant
Rash Maculo-papular Other Serious 9/8/2012 88 Male 12/31/2012 Other Health Professional Gb
Primary
Concomitant
Drug Interaction Hospitalization 10/22/2012 80 Male 190 lb 1/4/2013 Physician Ch
Primary
Concomitant
Interacting
Drug Interaction Hospitalization 10/22/2012 80 Male 190 lb 1/3/2013 Physician Ch
Primary
Concomitant
Interacting
Emphysema Other Serious 11/2012 Male 180 lb 3/29/2013 Consumer Us
Primary
Concomitant
Thrombocytopenia Other Serious 1/9/2013 74 Female 106 lb 2/22/2013 Physician Fr
Primary
Concomitant
Melaena Hospitalization 12/13/2012 72 Male 1/22/2013 Other Health Professional Ch
Primary
Concomitant
Interacting
Melaena Hospitalization 12/13/2012 72 Male 1/28/2013 Other Health Professional Ch
Primary
Secondary
Concomitant
Weight Increased Other Serious 7/31/2012 Female 130 lb 3/11/2013 Physician Ch
Primary
Concomitant
Hemiplegia Other Serious 80 Female 1/31/2013 Consumer Mx
Primary
Concomitant
Urine Viscosity Abnormal Other Serious 1/17/2013 78 Male 175 lb 2/1/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Pulmonary Embolism Death 12/3/2012 Female 146 lb 3/15/2013 Physician De
Primary
Concomitant
Urine Viscosity Abnormal Other Serious 1/17/2013 79 Male 175 lb 2/1/2013 Physician Us
Primary
Secondary
Concomitant
Vitamin B12 Deficiency Hospitalization 9/2012 Male 223 lb 2/1/2013 Consumer Us
Primary
Concomitant
Drug Interaction Hospitalization 10/22/2012 80 Male 190 lb 2/7/2013 Physician Ch
Primary
Secondary
Concomitant

Drug Data