Afinitor



Indications and Reactions:

Role Indications Reactions
Primary
Metastatic Renal Cell Carcinoma 34.8%
Renal Cell Carcinoma 13.4%
Breast Cancer Metastatic 7.3%
Breast Cancer 5.9%
Prophylaxis 5.1%
Hypertension 4.8%
Pancreatic Neuroendocrine Tumour 4.0%
Tuberous Sclerosis 4.0%
Renal Cancer 3.8%
Neuroendocrine Tumour 2.9%
Pain 2.1%
Carcinoid Tumour 1.7%
Diabetes Mellitus 1.7%
Metastatic Malignant Melanoma 1.5%
Renal Cancer Metastatic 1.5%
Neoplasm 1.3%
Acute Myeloid Leukaemia 1.2%
Glioblastoma Multiforme 1.2%
Neoplasm Malignant 1.1%
Nausea 1.0%
Death 27.0%
Neoplasm Malignant 8.7%
Vomiting 8.5%
Stomatitis 7.9%
Pyrexia 5.0%
Neoplasm Progression 3.9%
Malignant Neoplasm Progression 3.9%
Pneumonitis 3.9%
Pneumonia 3.5%
Thrombocytopenia 3.3%
Rash 3.1%
Weight Decreased 3.0%
Lung Disorder 2.4%
Pleural Effusion 2.4%
Renal Failure 2.4%
Diarrhoea 2.3%
Drug Ineffective 2.3%
Dyspnoea 2.1%
Urinary Tract Infection 2.1%
Malaise 2.1%
Secondary
Metastatic Renal Cell Carcinoma 42.0%
Prophylaxis 9.1%
Breast Cancer Metastatic 8.5%
Pancreatic Neuroendocrine Tumour 5.4%
Renal Cell Carcinoma 4.9%
Breast Cancer 3.8%
Hypertension 3.6%
Neuroendocrine Tumour 3.3%
Tuberous Sclerosis 3.2%
Carcinoid Tumour 3.0%
Pain 2.3%
Diabetes Mellitus 1.7%
Astrocytoma, Low Grade 1.3%
Renal Cancer 1.2%
Constipation 1.2%
Renal Cancer Metastatic 1.2%
Product Used For Unknown Indication 1.1%
Convulsion 1.1%
Metastases To Bone 1.1%
Hepatic Neoplasm Malignant 1.0%
Stomatitis 11.7%
Pyrexia 10.7%
Vomiting 9.7%
Neoplasm Malignant 7.9%
Weight Decreased 6.0%
Haemoglobin Decreased 5.0%
Platelet Count Decreased 4.5%
C-reactive Protein Increased 4.3%
Death 4.2%
Thrombocytopenia 4.0%
Diarrhoea 3.9%
Pneumonitis 3.9%
Urinary Tract Infection 3.9%
Malaise 3.3%
Neoplasm Progression 3.2%
Malignant Neoplasm Progression 2.9%
White Blood Cell Count Decreased 2.9%
Rash 2.8%
Lymphocyte Count Decreased 2.7%
Hyperglycaemia 2.5%
Concomitant
Product Used For Unknown Indication 27.6%
Metastases To Bone 12.6%
Renal Cancer 10.5%
Breast Cancer 9.6%
Breast Cancer Metastatic 7.9%
Renal Cell Carcinoma 6.3%
Neuroendocrine Tumour 2.9%
Pain 2.9%
Carcinoid Tumour 2.1%
Neoplasm Malignant 2.1%
Cough 1.7%
Diabetes Mellitus 1.7%
Disease Progression 1.7%
Metastatic Renal Cell Carcinoma 1.7%
Nausea 1.7%
Neuroendocrine Carcinoma Metastatic 1.7%
Prophylaxis 1.7%
Back Pain 1.3%
Bone Cancer 1.3%
Carcinoid Syndrome 1.3%
Death 10.0%
Febrile Neutropenia 10.0%
Weight Decreased 8.3%
Osteonecrosis Of Jaw 6.7%
Pain In Extremity 6.7%
Diarrhoea 5.0%
Disease Progression 5.0%
Mouth Ulceration 5.0%
Swelling Face 5.0%
Syncope 5.0%
Dementia 3.3%
Drug Ineffective 3.3%
General Physical Health Deterioration 3.3%
Grand Mal Convulsion 3.3%
Jaundice Cholestatic 3.3%
Malaise 3.3%
Mesenteric Occlusion 3.3%
Nasal Congestion 3.3%
Oral Pain 3.3%
Pain 3.3%
Interacting
Epilepsy 30.4%
Acute Myeloid Leukaemia 21.5%
Astrocytoma, Low Grade 15.2%
Renal Cell Carcinoma 10.1%
Glioblastoma Multiforme 3.8%
Pain 3.8%
Breast Cancer 2.5%
Breast Cancer Metastatic 2.5%
Hypertension 2.5%
Renal Cancer 2.5%
Insomnia 1.3%
Metastases To Bone 1.3%
Product Used For Unknown Indication 1.3%
Sedative Therapy 1.3%
Drug Interaction 37.5%
Complex Partial Seizures 12.5%
Cough 6.3%
Hepatotoxicity 6.3%
Pneumonitis 6.3%
Vaginal Discharge 6.3%
Blood Oestrogen Increased 3.1%
Gamma-glutamyltransferase Increased 3.1%
Osteonecrosis Of Jaw 3.1%
Renal Failure 3.1%
Spinal Pain 3.1%
Status Epilepticus 3.1%
Vomiting 3.1%
Weight Decreased 3.1%