Afinitor combined with Paclitaxel

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Febrile Neutropenia Other Serious 6/26/2009 Physician United Kingdom
Primary
Secondary
Respiratory Tract Infection Hospitalization 9/28/2009 Female 121 lb 12/23/2009 Physician Germany
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 7/23/2008 Female 130 lb 12/31/2009 Physician France
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 4/11/2009 Female 181 lb 1/20/2010 Physician France
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 4/11/2009 Female 181 lb 2/5/2010 Physician France
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2008 Female 98 lb 2/23/2010 Physician Australia
Primary
Concomitant
Influenza Like Illness Other Serious 12/14/2009 Female 222 lb 3/2/2010 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 1/26/2010 Female 118 lb 3/2/2010 Physician United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 4/14/2009 Female 137 lb 3/5/2010 Physician Australia
Primary
Concomitant
Helicobacter Infection Hospitalization 7/18/2008 Female 139 lb 3/11/2010 Physician France
Primary
Secondary
Concomitant
Sepsis Hospitalization 1/26/2010 Female 118 lb 3/12/2010 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 1/26/2010 Female 118 lb 3/22/2010 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 12/4/2007 Male 334 lb 3/22/2010 Physician United States
Primary
Secondary
Pyrexia Hospitalization 11/7/2009 53 Female 172 lb 3/31/2010 Physician France
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/1/2009 67 Female 188 lb 4/6/2010 Physician United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 3/30/2010 28 Female 161 lb 4/8/2010 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/30/2010 28 Female 161 lb 4/19/2010 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/14/2010 28 Female 157 lb 5/25/2010 Physician Germany
Primary
Secondary
Concomitant
Platelet Disorder Hospitalization 5/1/2010 Female 136 lb 6/4/2010 United States
Primary
Secondary
Pyrexia Hospitalization 4/25/2010 52 Male 212 lb 6/8/2010 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 5/29/2010 71 Female 106 lb 6/14/2010 Physician Mexico
Primary
Concomitant
Thrombocytopenia Life Threatening 5/29/2010 71 Female 106 lb 6/15/2010 Physician Mexico
Primary
Concomitant
Neutrophil Count Decreased Other Serious 4/20/2010 Female 195 lb 6/17/2010 Physician United States
Primary
Secondary
Thrombocytopenia Hospitalization 5/20/2010 66 Male 159 lb 6/18/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/7/2009 53 Female 172 lb 6/21/2010 Physician France
Primary
Concomitant
Vena Cava Filter Insertion Hospitalization 5/18/2010 52 Male 212 lb 6/30/2010 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 5/20/2010 66 Male 159 lb 7/2/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Vomiting Other Serious 3/25/2010 54 Male 192 lb 7/13/2010 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 7/9/2010 77 Female 145 lb 7/22/2010 Physician United States
Primary
Secondary
Concomitant
Tumour Associated Fever Hospitalization 4/25/2010 52 Male 212 lb 7/22/2010 Physician United States
Primary
Secondary
Concomitant
Vena Cava Filter Insertion Hospitalization 5/18/2010 52 Male 212 lb 7/22/2010 Physician United States
Primary
Secondary
Concomitant
Syncope Hospitalization 7/15/2010 73 Male 177 lb 7/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 7/9/2010 77 Female 145 lb 7/29/2010 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 7/23/2010 72 Male 166 lb 8/2/2010 Physician Korea, Republic Of
Primary
Secondary
Syncope Hospitalization 7/15/2010 73 Male 177 lb 8/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 7/8/2010 60 Female 185 lb 8/11/2010 Physician Germany
Primary
Secondary
Neutrophil Count Decreased Other Serious 5/3/2010 Female 189 lb 8/20/2010 Physician United States
Primary
Secondary
Syncope Hospitalization 7/15/2010 73 Male 177 lb 8/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Hospitalization 7/15/2010 73 Male 177 lb 8/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/9/2010 77 Female 145 lb 9/1/2010 Physician United States
Primary
Secondary
Concomitant
Syncope Hospitalization 7/15/2010 73 Male 177 lb 9/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 6/7/2010 79 Male 214 lb 9/3/2010 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 8/18/2010 Male 189 lb 9/7/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 3/25/2010 54 Male 192 lb 9/8/2010 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 6/7/2010 79 Male 214 lb 9/10/2010 Physician United States
Primary
Secondary
Concomitant
Platelet Disorder Hospitalization 3/22/2010 Female 136 lb 9/13/2010 United States
Primary
Secondary
Vomiting Other Serious 3/25/2010 54 Male 192 lb 9/13/2010 Physician United States
Primary
Secondary
Concomitant
Tracheostomy Hospitalization 7/8/2010 60 Female 185 lb 9/13/2010 Physician Germany
Primary
Secondary
Pyrexia Hospitalization 9/12/2010 36 143 lb 9/21/2010 Physician United States
Primary
Secondary
Thrombocytopenia Hospitalization 9/12/2010 36 143 lb 9/27/2010 Physician United States
Primary
Secondary
Vertigo Hospitalization 10/26/2010 45 Female 212 lb 11/5/2010 Physician Germany
Primary
Concomitant
Thrombocytopenia Life Threatening 5/19/2010 71 Female 106 lb 11/5/2010 Physician Mexico
Primary
Concomitant
Vena Cava Thrombosis Other Serious 9/21/2010 36 Female 183 lb 11/10/2010 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 10/26/2010 Male 220 lb 11/15/2010 Physician United States
Primary
Secondary
Vertigo Other Serious 10/1/2010 45 Female 212 lb 11/30/2010 Physician Germany
Primary
Concomitant
Febrile Neutropenia Hospitalization 12/22/2010 71 Male 222 lb 12/30/2010 Physician United States
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 10/26/2010 Male 220 lb 1/10/2011 Physician United States
Primary
Secondary
Pulmonary Embolism Hospitalization 9/21/2010 36 Female 183 lb 1/11/2011 Physician United States
Primary
Secondary
Concomitant
Asthenia Hospitalization 12/22/2010 71 Male 222 lb 1/13/2011 Physician United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Hospitalization 10/26/2010 Male 220 lb 1/13/2011 Physician United States
Primary
Secondary
Pyrexia Hospitalization 9/12/2010 36 143 lb 1/19/2011 Physician United States
Primary
Secondary
Concomitant
Helicobacter Infection Hospitalization 7/18/2008 67 Female 139 lb 1/25/2011 Physician France
Primary
Secondary
Concomitant
Anaemia Death 10/26/2010 Male 220 lb 2/2/2011 Physician United States
Primary
Secondary
Hypoxia Death 10/26/2010 Male 220 lb 2/7/2011 Physician United States
Primary
Secondary
Febrile Neutropenia Hospitalization 12/11/2010 61 Female 209 lb 2/25/2011 Physician Ireland
Primary
Secondary
Concomitant
Septic Shock Life Threatening 3/3/2011 37 Female 146 lb 3/16/2011 Physician United States
Primary
Secondary
Fall Hospitalization 3/6/2011 Female 132 lb 3/23/2011 Physician United States
Primary
Secondary
Cardiac Failure Death 10/26/2010 Male 220 lb 3/25/2011 Physician United States
Primary
Secondary
Pneumonia Death 2/15/2011 60 Female 134 lb 4/4/2011 Physician United States
Primary
Secondary
Concomitant
Asthenia Hospitalization 2/15/2011 60 Female 134 lb 4/6/2011 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 2/15/2011 60 Female 134 lb 4/7/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Hospitalization 4/12/2011 Female 190 lb 4/21/2011 Physician United States
Primary
Secondary
Anaemia Other Serious 67 Female 4/27/2011 Other Health Professional France
Primary
Secondary
Cerebral Ischaemia Life Threatening 5/19/2010 71 Female 106 lb 5/11/2011 Physician Mexico
Primary
Concomitant
Dyspnoea Hospitalization 7/23/2008 69 Female 130 lb 5/12/2011 Physician France
Primary
Secondary
Concomitant
Fatigue Hospitalization 5/6/2011 74 Female 99 lb 5/26/2011 Physician Ireland
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 5/6/2011 74 Female 99 lb 5/27/2011 Physician Ireland
Primary
Secondary
Concomitant
Sinus Disorder Other Serious 6/1/2011 58 119 lb 6/16/2011 Physician Taiwan, Province Of China
Primary
Secondary
General Physical Health Deterioration Hospitalization 4/25/2011 54 Male 251 lb 7/8/2011 Physician Germany
Primary
Secondary
Concomitant
Concomitant Disease Progression Disability 5/24/2011 39 Female 126 lb 7/14/2011 Physician Brazil
Primary
Secondary
Concomitant
Multi-organ Failure Hospitalization 7/23/2011 77 Male 203 lb 7/28/2011 Physician Germany
Primary
Secondary
Concomitant
Hypotension Hospitalization 7/26/2011 70 Male 180 lb 8/12/2011 Other Health Professional United States
Primary
Secondary
Ocular Surface Disease Other Serious 9/2/2011 60 Female 120 lb 9/12/2011 Physician Hong Kong
Primary
Secondary
Febrile Neutropenia Hospitalization 8/30/2011 69 Male 209 lb 9/13/2011 Other Health Professional Germany
Primary
Secondary
Febrile Neutropenia Hospitalization 8/30/2011 69 Male 209 lb 9/20/2011 Other Health Professional Germany
Primary
Secondary
Ocular Surface Disease Other Serious 9/2/2011 60 Female 120 lb 9/29/2011 Other Health Professional Hong Kong
Primary
Secondary
Oedema Hospitalization 12/13/2009 69 Female 119 lb 10/6/2011 Physician Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 12/11/2010 61 Female 209 lb 10/14/2011 Physician Ireland
Primary
Secondary
Concomitant
Pallor Hospitalization 9/14/2010 62 Female 173 lb 10/20/2011 Physician South Africa
Primary
Secondary
Concomitant
Cardiac Failure Congestive Death 9/14/2010 62 Female 173 lb 10/20/2011 Physician South Africa
Primary
Secondary
Concomitant
Pleural Effusion Death 9/14/2010 62 Female 173 lb 10/25/2011 Physician South Africa
Primary
Secondary
Concomitant
Hypokalaemia Disability 10/28/2011 50 Female 137 lb 11/11/2011 Other Health Professional Brazil
Primary
Secondary
Catheter Site Infection Hospitalization 1/5/2011 61 Female 209 lb 11/28/2011 Physician Ireland
Primary
Secondary
Concomitant
Hypokalaemia Disability 10/28/2011 50 Female 137 lb 11/28/2011 Other Health Professional Brazil
Primary
Secondary
Cholecystitis Hospitalization 3/31/2011 64 Female 137 lb 11/28/2011 Physician Brazil
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 9/14/2010 62 Female 173 lb 11/29/2011 Physician South Africa
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 10/28/2011 50 Female 137 lb 11/29/2011 Physician Brazil
Primary
Secondary
Decreased Appetite Hospitalization 5/2/2011 74 Female 99 lb 11/30/2011 Physician Ireland
Primary
Secondary
Concomitant
Fatigue Hospitalization 4/24/2011 73 Female 139 lb 11/30/2011 Other Health Professional Germany
Primary
Secondary
Alanine Aminotransferase Increased Other Serious 2/23/2011 58 Female 132 lb 11/30/2011 Physician South Africa
Primary
Secondary
Concomitant
Anaemia Other Serious 12/13/2009 69 Female 119 lb 11/30/2011 Physician Japan
Primary
Secondary
Concomitant
Paraesthesia Hospitalization 7/28/2010 77 Female 12/1/2011 Physician United States
Primary
Secondary
Abdominal Pain Hospitalization 12/22/2010 71 Male 207 lb 12/2/2011 Physician United States
Primary
Secondary
Concomitant
Decreased Appetite Hospitalization 5/2/2011 74 Female 99 lb 12/2/2011 Physician Ireland
Primary
Secondary
Concomitant
Epistaxis Other Serious 12/13/2009 69 Female 119 lb 12/2/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 5/27/2011 59 Female 108 lb 12/5/2011 Physician China
Primary
Secondary
Diarrhoea Disability 10/28/2011 50 Female 137 lb 12/9/2011 Other Health Professional Brazil
Primary
Secondary
Dehydration Hospitalization 9/14/2010 62 Female 173 lb 12/9/2011 Physician South Africa
Primary
Secondary
Concomitant
Pyrexia Death 2/15/2011 60 Female 134 lb 1/6/2012 Physician United States
Primary
Secondary
Concomitant
Pneumonia Klebsiella Hospitalization 11/1/2011 63 Female 190 lb 1/24/2012 Physician Belgium
Primary
Secondary
Concomitant
Liver Disorder Other Serious 12/13/2009 69 Female 119 lb 2/10/2012 Physician Japan
Primary
Secondary
Concomitant
Dizziness Hospitalization 7/28/2010 77 Female 2/22/2012 Physician United States
Primary
Secondary
Gastritis Other Serious 2/23/2011 58 Female 132 lb 2/27/2012 Physician South Africa
Primary
Secondary
Concomitant
Device Related Infection Hospitalization 11/21/2010 41 Female 123 lb 2/28/2012 Physician Brazil
Primary
Secondary
Concomitant
Paraesthesia Other Serious 7/28/2010 77 Female 3/2/2012 Physician United States
Primary
Secondary
Anaemia Hospitalization 2/24/2012 45 Female 186 lb 3/2/2012 Physician United States
Primary
Secondary
Concomitant
Pneumonia Pneumococcal Hospitalization 2/24/2012 45 Female 186 lb 3/13/2012 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 4/24/2011 73 Female 139 lb 3/14/2012 Other Health Professional Germany
Primary
Secondary
Urinary Tract Infection Hospitalization 3/5/2012 53 Female 273 lb 3/15/2012 Physician United States
Primary
Secondary
Infection Hospitalization 4/24/2011 73 Female 139 lb 3/20/2012 Other Health Professional Germany
Primary
Secondary
Hepatic Function Abnormal Other Serious 2/23/2011 58 Female 132 lb 3/23/2012 Physician South Africa
Primary
Secondary
Concomitant
Colitis Ischaemic Hospitalization 11/11/2011 63 Female 111 lb 3/26/2012 Physician Ireland
Primary
Secondary
Concomitant
Cough Hospitalization 12/7/2010 51 Female 179 lb 3/27/2012 Physician Brazil
Primary
Secondary
Concomitant
Nausea Other Serious 2/23/2011 58 Female 132 lb 3/27/2012 Physician South Africa
Primary
Secondary
Concomitant
Metastases To Central Nervous System Hospitalization 3/10/2012 43 Female 121 lb 3/27/2012 Physician United States
Primary
Secondary
Hyponatraemia Hospitalization 9/30/2010 60 Female 115 lb 3/29/2012 Physician South Africa
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/8/2012 48 Female 137 lb 4/2/2012 Physician Lebanon
Primary
Secondary
Concomitant
Hypovolaemia Disability 5/19/2010 71 Female 106 lb 4/9/2012 Physician Mexico
Primary
Concomitant
Colitis Ischaemic Hospitalization 11/11/2011 63 Female 111 lb 4/9/2012 Physician Ireland
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/8/2012 48 Female 137 lb 4/12/2012 Physician Lebanon
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 11/21/2010 41 Female 123 lb 4/17/2012 Physician Brazil
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 11/30/2011 52 Female 114 lb 4/19/2012 Physician Korea, Republic Of
Primary
Secondary
Streptococcal Urinary Tract Infection Hospitalization 2/24/2012 45 Female 186 lb 4/20/2012 Physician United States
Primary
Secondary
Concomitant
Colitis Ischaemic Hospitalization 11/11/2011 63 Female 111 lb 4/23/2012 Other Health Professional Ireland
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 5/19/2010 71 Female 106 lb 4/24/2012 Physician Mexico
Primary
Secondary
Colitis Ischaemic Hospitalization 11/11/2011 63 Female 111 lb 4/25/2012 Other Health Professional Ireland
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 9/30/2010 60 Female 115 lb 4/27/2012 Physician South Africa
Primary
Secondary
Concomitant
Metastases To Central Nervous System Other Serious 3/10/2012 43 Female 122 lb 4/30/2012 Physician United States
Primary
Secondary
Concomitant
Gastritis Hospitalization 1/10/2012 63 Female 225 lb 5/10/2012 Physician South Africa
Primary
Secondary
Concomitant
Hypokalaemia Life Threatening 9/30/2010 60 Female 115 lb 5/14/2012 Physician South Africa
Primary
Secondary
Concomitant
Renal Impairment Death 9/30/2010 60 Female 115 lb 6/19/2012 Physician South Africa
Primary
Secondary
Concomitant
Renal Impairment Life Threatening 9/7/2010 60 Female 115 lb 6/27/2012 Physician South Africa
Primary
Secondary
Concomitant
Cerebral Ischaemia Disability 5/29/2010 71 Female 106 lb 6/28/2012 Physician Mexico
Primary
Secondary
Pneumocystis Jiroveci Pneumonia Hospitalization 2/8/2010 69 Female 119 lb 7/2/2012 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 5/29/2011 52 Male 116 lb 7/3/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Hospitalization 12/13/2010 71 Male 158 lb 7/4/2012 Physician United States
Primary
Secondary
Concomitant
Oesophageal Obstruction Hospitalization 12/14/2010 66 Female 125 lb 7/12/2012 Physician United States
Primary
Secondary
Concomitant
Pyrexia Life Threatening 2/15/2011 60 Female 134 lb 7/12/2012 Physician United States
Primary
Secondary
Concomitant
Escherichia Infection Hospitalization 2/15/2011 60 Female 134 lb 7/16/2012 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 3/5/2012 53 Female 273 lb 7/20/2012 Physician United States
Primary
Secondary

Drug Data