Afinitor combined with Omeprazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Respiratory Rate Increased Hospitalization Male 168 lb 11/28/2009 Physician United Kingdom
Primary
Concomitant
Pericardial Effusion Life Threatening 7/27/2009 Female 121 lb 11/27/2009 Physician Spain
Primary
Concomitant
Vomiting Hospitalization 10/1/2009 Female 116 lb 11/29/2009 Physician Canada
Primary
Concomitant
Pyrexia Hospitalization 10/4/2009 Male 198 lb 12/2/2009 Physician Finland
Primary
Concomitant
Vaginal Discharge Other Serious 11/2/2009 Female 12/3/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/1/2009 Female 116 lb 12/9/2009 Physician Canada
Primary
Concomitant
Vital Functions Abnormal Other Serious 10/22/2009 56 Female 12/14/2009 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 8/22/2009 Female 12/14/2009 Physician Belgium
Primary
Concomitant
Pericardial Effusion Life Threatening 7/27/2009 Female 121 lb 12/21/2009 Physician Spain
Primary
Concomitant
Pericardial Effusion Life Threatening 7/27/2009 Female 121 lb 12/23/2009 Physician Spain
Primary
Concomitant
Weight Decreased Other Serious 9/11/2009 Female 115 lb 1/11/2010 Physician United States
Primary
Secondary
Concomitant
Urticaria Other Serious 12/1/2009 Male 178 lb 1/18/2010 United States
Primary
Concomitant
Pruritus Disability 10/3/2009 Male 1/25/2010 Physician United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 9/11/2009 Female 115 lb 2/10/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 12/11/2009 Male 160 lb 2/16/2010 Other Health Professional United States
Primary
Concomitant
Pyrexia Hospitalization 10/4/2009 Male 198 lb 2/19/2010 Physician Finland
Primary
Concomitant
Pericardial Effusion Life Threatening 7/27/2009 Female 121 lb 2/22/2010 Physician Spain
Primary
Concomitant
Pruritus Disability 10/27/2009 Male 3/2/2010 Physician United Kingdom
Primary
Concomitant
Septic Shock Hospitalization 1/11/2010 Male 3/9/2010 Physician Belgium
Primary
Concomitant
Septic Shock Hospitalization 12/11/2009 Male 3/16/2010 Physician Belgium
Primary
Concomitant
Renal Impairment Other Serious Male 3/18/2010 Physician Belgium
Primary
Secondary
Concomitant
Blood Urea Increased 8/16/2009 46 Female 4/3/2010 Physician United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 4/1/2010 80 Female 4/23/2010 Physician United States
Primary
Secondary
Concomitant
Mental Status Changes Other Serious 2/1/2010 69 Male 5/4/2010 Physician Switzerland
Primary
Concomitant
Vomiting Other Serious 1/23/2010 47 Female 5/12/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/11/2009 60 Female 115 lb 5/13/2010 Physician United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 10/4/2009 68 Male 198 lb 5/13/2010 Physician Finland
Primary
Concomitant
Vital Functions Abnormal Other Serious 10/22/2009 56 Female 5/14/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 4/1/2010 80 Female 5/28/2010 Physician United States
Primary
Secondary
Concomitant
Vaginal Discharge Other Serious 11/2/2009 63 Female 6/15/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Vaginal Discharge Other Serious 11/2/2009 63 Female 6/16/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Interacting
Osteopenia Hospitalization 2/2/2010 42 Male 223 lb 6/22/2010 Physician Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/26/2010 60 Male 162 lb 7/7/2010 Physician United States
Primary
Concomitant
Vomiting Hospitalization 5/26/2010 60 Male 162 lb 7/15/2010 Physician United States
Primary
Concomitant
Osteopenia Hospitalization 2/2/2010 42 Male 223 lb 7/16/2010 Physician Germany
Primary
Secondary
Concomitant
Thrombosis Other Serious 7/9/2010 Male 7/23/2010 United States
Primary
Concomitant
Vaginal Discharge Other Serious 11/2/2009 63 Female 7/30/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Interacting
Vocal Cord Paralysis Other Serious 3/3/2010 52 Male 8/19/2010 United States
Primary
Concomitant
Sepsis Hospitalization 5/24/2010 61 Male 199 lb 8/20/2010 Physician United States
Primary
Concomitant
Coronary Artery Insufficiency Life Threatening 5/21/2010 68 Female 138 lb 9/8/2010 Physician Germany
Primary
Secondary
Concomitant
Osteopenia Hospitalization 2/2/2010 42 Male 223 lb 9/14/2010 Physician Germany
Primary
Secondary
Concomitant
Concomitant Disease Progression Life Threatening 5/21/2010 68 Female 138 lb 9/16/2010 Physician Germany
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Hospitalization 9/8/2010 72 Male 182 lb 9/17/2010 Physician United States
Primary
Concomitant
Rash Macular Hospitalization 9/8/2010 72 Male 182 lb 10/7/2010 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 9/8/2010 72 Male 182 lb 10/12/2010 Physician United States
Primary
Concomitant
Pain Hospitalization 10/1/2010 52 Female 137 lb 10/19/2010 Physician United States
Primary
Concomitant
Septic Shock Other Serious 10/11/2010 43 Female 10/22/2010 Physician United Kingdom
Primary
Concomitant
Rash Macular Hospitalization 8/9/2010 72 Male 182 lb 10/27/2010 Physician United States
Primary
Concomitant
Septic Shock Other Serious 10/11/2010 43 Female 10/29/2010 Physician United Kingdom
Primary
Concomitant
Oral Pain Death 62 Female 179 lb 11/3/2010 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 10/1/2010 69 Male 154 lb 11/5/2010 Physician United States
Primary
Concomitant
Vomiting Hospitalization 10/1/2009 43 Female 116 lb 11/25/2010 Physician Canada
Primary
Concomitant
Respiratory Failure Hospitalization 9/8/2010 72 Male 182 lb 12/17/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 10/1/2009 43 Female 116 lb 12/20/2010 Physician Canada
Primary
Concomitant
Transfusion Reaction Hospitalization 12/3/2010 73 Female 148 lb 12/24/2010 Physician United States
Primary
Secondary
Concomitant
Venous Thrombosis Other Serious 12/17/2010 43 Male 12/30/2010 Physician Colombia
Primary
Concomitant
Tremor Hospitalization 12/28/2010 58 Male 173 lb 1/7/2011 Physician United States
Primary
Secondary
Concomitant
Anaemia Other Serious 5/17/2010 73 Male 1/12/2011 Physician Germany
Primary
Concomitant
Chest Tube Insertion Hospitalization 12/1/2010 61 Female 64 lb 1/17/2011 Physician United States
Primary
Concomitant
Gastrointestinal Ischaemia Other Serious 10/1/2009 43 Female 116 lb 2/15/2011 Physician Canada
Primary
Concomitant
Diarrhoea Hospitalization 12/10/2010 Male 170 lb 2/16/2011 Physician United States
Primary
Secondary
Concomitant
Skin Toxicity Other Serious 1/28/2011 51 Male 2/23/2011 Other Health Professional Italy
Primary
Concomitant
Dyspnoea Hospitalization 12/1/2010 61 Female 64 lb 2/25/2011 Physician United States
Primary
Concomitant
Death Death Male 3/8/2011 Consumer United States
Primary
Concomitant
Hypotension Death 9/8/2010 72 Male 182 lb 3/29/2011 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 12/10/2010 Male 170 lb 3/31/2011 Physician United States
Primary
Secondary
Concomitant
Malaise Hospitalization 12/10/2010 Male 170 lb 4/4/2011 Physician United States
Primary
Secondary
Concomitant
Skin Toxicity Other Serious 1/28/2011 51 Male 4/7/2011 Physician Italy
Primary
Concomitant
Hepatotoxicity Hospitalization 5/29/2010 60 Male 158 lb 4/13/2011 Physician Brazil
Primary
Secondary
Concomitant
Confusional State Hospitalization 4/6/2011 4/13/2011 Physician United Kingdom
Primary
Concomitant
Death Death Male 4/22/2011 Consumer United States
Primary
Concomitant
Anaemia Hospitalization 4/6/2011 49 Male 4/22/2011 Physician United Kingdom
Primary
Concomitant
Immunosuppression Other Serious 2/14/2011 56 Male 4/27/2011 Physician Spain
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious Male 5/4/2011 Physician Japan
Primary
Concomitant
Pancreatitis Hospitalization 4/21/2011 78 Female 142 lb 5/6/2011 Physician United States
Primary
Secondary
Concomitant
Death Death 5/9/2011 Physician United Kingdom
Primary
Concomitant
Vomiting Other Serious 3/27/2011 62 Male 185 lb 5/9/2011 Physician United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Death 2/27/2011 64 Female 132 lb 5/9/2011 Physician Italy
Primary
Concomitant
Hypersensitivity Hospitalization 4/21/2011 78 Female 142 lb 5/17/2011 Physician United States
Primary
Secondary
Concomitant
Blood Lactate Dehydrogenase Increased Other Serious 4/27/2011 63 Male 5/24/2011 Physician Japan
Primary
Concomitant
Neoplasm Malignant Hospitalization 8/9/2010 63 Female 5/31/2011 Physician Japan
Primary
Secondary
Concomitant
Infection Other Serious 7/12/2010 73 Male 134 lb 5/26/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 5/29/2010 60 Male 158 lb 6/16/2011 Physician Brazil
Primary
Secondary
Concomitant
Blood Lactate Dehydrogenase Increased Other Serious 4/27/2011 63 Male 7/5/2011 Physician Japan
Primary
Concomitant
Metastases To Lung Other Serious 6/26/2011 57 Male 7/13/2011 Other Health Professional Colombia
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/8/2011 74 Female 7/27/2011 Consumer United States
Primary
Concomitant
Anaemia Death 6/26/2011 57 Male 7/29/2011 Other Health Professional Colombia
Primary
Concomitant
Hyperglycaemia Other Serious 8/9/2010 61 Male 139 lb 8/16/2011 Physician Japan
Primary
Concomitant
Asthenia Hospitalization 7/4/2011 64 Female 214 lb 8/23/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Decreased Appetite Death 6/26/2011 57 Male 8/24/2011 Other Health Professional Colombia
Primary
Concomitant
Pulmonary Mass Hospitalization 5/7/2011 78 Male 126 lb 8/30/2011 Physician Germany
Primary
Concomitant
Blood Urea Increased Hospitalization 7/4/2011 64 Female 214 lb 9/6/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Fibrin D Dimer Increased Hospitalization 4/1/2011 60 Male 165 lb 9/13/2011 Physician Germany
Primary
Concomitant
C-reactive Protein Increased Hospitalization 3/14/2011 60 Male 9/16/2011 Physician Japan
Primary
Concomitant
Blood Lactate Dehydrogenase Increased Other Serious 4/15/2011 63 Male 9/20/2011 Physician Japan
Primary
Concomitant
Hypercreatininaemia Hospitalization Male 10/4/2011 Other Health Professional France
Primary
Concomitant
Colitis Ischaemic Hospitalization 9/30/2011 61 Female 151 lb 10/11/2011 Physician United States
Primary
Concomitant
C-reactive Protein Increased Other Serious 8/9/2010 61 Male 139 lb 10/20/2011 Physician Japan
Primary
Concomitant
Blood Lactate Dehydrogenase Increased Hospitalization 4/27/2011 63 Male 10/25/2011 Physician Japan
Primary
Concomitant
Diabetic Ketoacidosis Hospitalization 11/3/2011 75 Female 11/11/2011 Physician Spain
Primary
Secondary
Concomitant
Arthritis Bacterial Hospitalization 11/14/2011 48 Male 11/24/2011 Physician United States
Primary
Secondary
Concomitant
Circulatory Collapse Other Serious 11/12/2011 59 Male 159 lb 11/24/2011 Physician Germany
Primary
Concomitant
General Physical Health Deterioration Hospitalization 11/3/2011 75 Female 11/25/2011 Physician Spain
Primary
Secondary
Concomitant
Cholecystitis Hospitalization 3/31/2011 64 Female 137 lb 11/28/2011 Physician Brazil
Primary
Secondary
Concomitant
Arthritis Bacterial Hospitalization 11/14/2011 48 Male 11/30/2011 Physician United States
Primary
Secondary
Concomitant
Neoplasm Progression Hospitalization 5/2/2010 69 Male 12/1/2011 Physician Japan
Primary
Concomitant
Generalised Oedema Hospitalization 10/3/2011 57 Male 12/5/2011 Physician Spain
Primary
Concomitant
Vomiting Hospitalization 11/22/2010 71 Male 115 lb 12/6/2011 Physician France
Primary
Concomitant
Metastatic Renal Cell Carcinoma Hospitalization 4/14/2011 65 Male 174 lb 12/8/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Dysgeusia Male 10/7/2011 Consumer United States
Primary
Concomitant
Faeces Discoloured 61 Female 10/7/2011 Consumer United States
Primary
Secondary
Concomitant
Neoplasm Malignant Death Female 214 lb 10/7/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/20/2010 76 Male 12/20/2011 Physician Japan
Primary
Secondary
Concomitant
Neoplasm Malignant Other Serious 8/9/2010 63 Female 12/21/2011 Physician Japan
Primary
Secondary
Concomitant
Hypocapnia Other Serious 9/1/2011 71 Male 154 lb 12/23/2011 Physician France
Primary
Concomitant
Dyspnoea Exertional Hospitalization 4/14/2011 65 Male 174 lb 12/26/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 8/20/2010 76 Male 12/26/2011 Physician Japan
Primary
Secondary
Concomitant
Neoplasm Malignant Other Serious Male 187 lb 1/2/2012 Consumer United States
Primary
Concomitant
Dry Skin Hospitalization Female 1/4/2012 Consumer Brazil
Primary
Concomitant
Diarrhoea Hospitalization 12/4/2011 60 Female 154 lb 1/11/2012 Consumer Brazil
Primary
Secondary
Concomitant
Circulatory Collapse Other Serious 11/12/2011 59 Male 159 lb 1/17/2012 Physician Germany
Primary
Concomitant
Chest Pain Hospitalization 12/2/2011 77 Male 1/24/2012 Other Health Professional Sweden
Primary
Concomitant
Weight Decreased Life Threatening Female 139 lb 1/24/2012 Physician United States
Primary
Secondary
Concomitant
Pneumonia Klebsiella Hospitalization 11/1/2011 63 Female 190 lb 1/24/2012 Physician Belgium
Primary
Secondary
Concomitant
Concomitant Disease Progression Other Serious 10/10/2011 85 Female 234 lb 1/27/2012 Physician United States
Primary
Concomitant
Hypertension Hospitalization 12/1/2011 Male 2/6/2012 Physician Czech Republic
Primary
Concomitant
Dyspnoea Hospitalization 12/22/2011 70 Female 130 lb 2/8/2012 Physician Germany
Primary
Concomitant
Diarrhoea Hospitalization 1/22/2012 57 Female 137 lb 2/22/2012 Physician Czech Republic
Primary
Secondary
Concomitant
Leukopenia Death 84 Female 2/22/2012 Physician Spain
Primary
Concomitant
Device Related Infection Hospitalization 11/21/2010 41 Female 123 lb 2/28/2012 Physician Brazil
Primary
Secondary
Concomitant
Urinary Tract Infection 56 Female 1/4/2012 Consumer United States
Primary
Concomitant
Fatigue Male 181 lb 1/4/2012 Physician United States
Primary
Concomitant
Neoplasm Malignant Death 64 Female 214 lb 1/4/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Fatigue 3/23/2011 73 Female 125 lb 7/5/2011 Consumer United States
Primary
Concomitant
Feeling Drunk 69 Female 7/5/2011 Consumer United States
Primary
Secondary
Concomitant
Dizziness 3/23/2011 73 Female 125 lb 7/5/2011 Consumer United States
Primary
Concomitant
Formication 69 Female 7/5/2011 Consumer United States
Primary
Secondary
Concomitant
Dysuria Female 7/9/2009 Consumer United States
Primary
Concomitant
Neoplasm Malignant Hospitalization 7/8/2010 50 Female 174 lb 10/5/2010 Other Health Professional United States
Primary
Concomitant
Pneumonia Escherichia Death 7/8/2010 50 Female 174 lb 10/5/2010 Other Health Professional United States
Primary
Concomitant
Joint Stiffness Other Serious 9/26/2010 63 Female 170 lb 4/7/2011 Other Health Professional United States
Primary
Concomitant
Haemorrhage Other Serious 2/18/2011 80 Female 136 lb 4/7/2011 Other Health Professional United States
Primary
Concomitant
Fatigue Other Serious 9/26/2010 63 Female 170 lb 4/7/2011 Other Health Professional United States
Primary
Concomitant
Cough Hospitalization 12/7/2010 51 Female 179 lb 3/27/2012 Physician Brazil
Primary
Secondary
Concomitant
Dysphagia Disability 11/11/2011 80 Male 130 lb 4/2/2012 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 5/29/2010 60 Male 158 lb 4/16/2012 Physician Brazil
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 11/21/2010 41 Female 123 lb 4/17/2012 Physician Brazil
Primary
Secondary
Concomitant
Uterine Leiomyoma Hospitalization 4/11/2012 46 Female 148 lb 4/18/2012 Physician France
Primary
Concomitant
Death Death 4/17/2012 55 Male 4/23/2012 Consumer United States
Primary
Concomitant
Metastases To Liver Hospitalization 8/20/2010 76 Male 4/23/2012 Physician Japan
Primary
Secondary
Concomitant

Drug Data