Afinitor combined with Lasix

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Other Serious 7/9/2009 Male 160 lb 8/17/2009 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 9/9/2009 Male 10/22/2009 Physician United States
Primary
Concomitant
Thrombosis Death 8/23/2009 Male 152 lb 11/20/2009 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/16/2009 Female 142 lb 11/27/2009 Physician United States
Primary
Secondary
Concomitant
Vital Functions Abnormal Other Serious 10/22/2009 56 Female 12/14/2009 Physician United States
Primary
Secondary
Concomitant
Thrombosis Death 8/18/2009 Male 12/16/2009 Physician Canada
Primary
Concomitant
Urosepsis Life Threatening 10/4/2009 Female 12/23/2009 Physician Australia
Primary
Concomitant
Respiratory Arrest Other Serious 1/15/2010 Male 1/28/2010 United States
Primary
Concomitant
Sinus Tachycardia Other Serious 1/5/2010 Female 142 lb 2/7/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/18/2009 Male 2/19/2010 Physician Belgium
Primary
Secondary
Concomitant
Death Death 1/15/2010 Male 3/15/2010 Physician Belgium
Primary
Concomitant
Weight Decreased Hospitalization 4/1/2010 80 Female 4/23/2010 Physician United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 3/26/2010 52 Male 187 lb 4/26/2010 Physician Italy
Primary
Concomitant
Respiratory Distress Other Serious 4/2/2010 81 Male 4/28/2010 United States
Primary
Concomitant
Thrombocytopenia Other Serious 12/1/2009 72 Female 5/5/2010 United States
Primary
Concomitant
Vomiting Hospitalization 4/22/2010 68 Male 207 lb 5/14/2010 Physician United States
Primary
Secondary
Concomitant
Vital Functions Abnormal Other Serious 10/22/2009 56 Female 5/14/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/22/2010 68 Male 207 lb 5/24/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 4/1/2010 80 Female 5/28/2010 Physician United States
Primary
Secondary
Concomitant
Thrombosis Death 8/18/2009 77 Male 6/1/2010 Physician Canada
Primary
Concomitant
Sinus Tachycardia Other Serious 12/22/2009 46 Female 142 lb 6/11/2010 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 3/7/2010 73 Female 6/14/2010 United States
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 12/30/2008 62 Female 141 lb 6/25/2010 Physician France
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 4/7/2010 63 Male 178 lb 6/25/2010 United States
Primary
Concomitant
Neutropenia Hospitalization Male 6/26/2010 Physician United States
Primary
Secondary
Concomitant
Urosepsis Life Threatening 10/4/2009 79 Female 7/2/2010 Physician Australia
Primary
Concomitant
Urosepsis Life Threatening 10/4/2009 79 Female 7/16/2010 Physician Australia
Primary
Concomitant
Urosepsis Life Threatening 10/4/2009 79 Female 7/17/2010 Physician Australia
Primary
Concomitant
Platelet Count Decreased Other Serious 5/26/2010 71 Male 7/28/2010 Physician Japan
Primary
Concomitant
Pneumonitis Hospitalization Female 160 lb 8/3/2010 United States
Primary
Concomitant
Respiratory Disorder Hospitalization 6/29/2010 68 Female 115 lb 8/13/2010 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 5/1/2010 69 Male 9/3/2010 Physician Japan
Primary
Concomitant
Pneumonia Bacterial Other Serious 4/14/2010 48 Male 9/7/2010 Physician Japan
Primary
Concomitant
Thrombocytopenia Hospitalization 8/18/2010 Male 189 lb 9/7/2010 Physician United States
Primary
Secondary
Concomitant
Respiratory Disorder Other Serious 4/14/2010 48 Male 9/13/2010 Physician Japan
Primary
Concomitant
Urosepsis Other Serious 10/4/2009 79 Female 9/17/2010 Physician Australia
Primary
Concomitant
Urosepsis Other Serious 10/4/2009 79 Female 9/20/2010 Physician Australia
Primary
Concomitant
Platelet Disorder Other Serious 6/12/2010 73 Male 9/21/2010 Physician Japan
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 5/31/2010 62 Male 126 lb 9/24/2010 Physician Japan
Primary
Concomitant
Thrombophlebitis Hospitalization 8/1/2010 70 Female 10/5/2010 Physician Japan
Primary
Concomitant
Death Death 5/6/2010 82 Male 10/7/2010 Physician Canada
Primary
Concomitant
Death Death 5/6/2010 82 Male 10/7/2010 Physician Canada
Primary
Concomitant
Respiratory Disorder Hospitalization 6/29/2010 68 Female 115 lb 10/11/2010 Physician Japan
Primary
Concomitant
Thrombocytopenia Hospitalization 8/18/2010 Male 189 lb 10/19/2010 Physician United States
Primary
Secondary
Concomitant
Glycosylated Haemoglobin Increased Other Serious Male 123 lb 10/20/2010 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 10/6/2010 Male 140 lb 10/20/2010 Physician United States
Primary
Concomitant
Malaise Hospitalization 8/10/2010 76 Male 123 lb 10/29/2010 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 8/16/2010 61 Male 11/2/2010 Physician Japan
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 5/31/2010 62 Male 126 lb 11/12/2010 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 3/20/2010 60 Male 11/15/2010 Physician Japan
Primary
Concomitant
Tumour Haemorrhage Life Threatening 7/2/2010 71 Female 104 lb 11/17/2010 Physician Japan
Primary
Secondary
Concomitant
Respiratory Disorder Hospitalization 6/29/2010 68 Female 115 lb 11/19/2010 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 11/9/2010 65 Male 217 lb 11/22/2010 Physician United States
Primary
Concomitant
Stomatitis Hospitalization 5/2/2010 69 Male 11/29/2010 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 9/30/2010 71 Male 11/30/2010 Physician Canada
Primary
Concomitant
Haemoglobin Decreased Other Serious Male 11/30/2010 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 6/28/2010 59 Male 11/30/2010 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 11/9/2010 65 Male 217 lb 12/3/2010 Physician United States
Primary
Concomitant
Death Death 9/8/2010 62 Male 12/9/2010 Physician Japan
Primary
Concomitant
Herpes Zoster Hospitalization 7/7/2010 55 Male 168 lb 12/16/2010 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 8/9/2010 63 Female 12/16/2010 Physician Japan
Primary
Concomitant
Malignant Neoplasm Progression Death 9/8/2010 62 Male 12/17/2010 Physician Japan
Primary
Concomitant
Acne Other Serious 9/2/2010 66 Male 146 lb 12/20/2010 Physician Japan
Primary
Concomitant
Haematocrit Increased Other Serious 9/9/2010 63 Male 123 lb 12/21/2010 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 10/6/2010 Male 140 lb 12/22/2010 Physician United States
Primary
Concomitant
Blood Potassium Decreased Hospitalization 6/12/2010 57 Female 12/23/2010 United States
Primary
Concomitant
Platelet Count Decreased Other Serious 8/2/2010 61 Male 12/23/2010 Physician Japan
Primary
Concomitant
Death Death Female 12/24/2010 Germany
Primary
Concomitant
Right Ventricle Outflow Tract Obstruction Other Serious 4/14/2010 48 Male 12/30/2010 Physician Japan
Primary
Concomitant
C-reactive Protein Increased Other Serious 6/12/2010 73 Male 12/30/2010 Physician Japan
Primary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 8/4/2010 31 Male 1/5/2011 Physician Japan
Primary
Concomitant
Cancer Pain Death 4/14/2010 48 Male 1/6/2011 Physician Japan
Primary
Concomitant
Blood Potassium Decreased Other Serious 7/12/2010 73 Male 134 lb 1/7/2011 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization 10/6/2010 Male 140 lb 1/12/2011 Physician United States
Primary
Concomitant
C-reactive Protein Increased Hospitalization 8/10/2010 76 Male 123 lb 1/24/2011 Physician Japan
Primary
Concomitant
Cancer Pain Hospitalization 4/14/2010 48 Male 1/24/2011 Physician Japan
Primary
Concomitant
Blood Glucose Increased Other Serious 12/23/2010 82 Female 1/24/2011 Consumer Germany
Primary
Concomitant
Oedema Peripheral Hospitalization 8/1/2010 70 Female 1/24/2011 Physician Japan
Primary
Concomitant
Dizziness Other Serious 12/27/2010 82 Female 133 lb 2/2/2011 Consumer Germany
Primary
Concomitant
Pneumonia Aspiration Other Serious Male 2/2/2011 Physician Japan
Primary
Concomitant
Acne Other Serious 9/2/2010 66 Male 146 lb 2/2/2011 Physician Japan
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 1/13/2011 88 Male 2/7/2011 Physician United States
Primary
Concomitant
Haemoglobin Decreased Death 12/10/2010 71 Male 119 lb 2/15/2011 Physician Japan
Primary
Concomitant
Hyperglycaemia Hospitalization 6/28/2010 59 Male 2/17/2011 Physician Japan
Primary
Concomitant
Herpes Zoster Hospitalization 7/7/2010 55 Male 168 lb 2/22/2011 Physician Japan
Primary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 10/21/2010 61 Female 2/28/2011 Physician Japan
Primary
Concomitant
Death Death Male 2/28/2011 Physician United States
Primary
Concomitant
Blood Urea Increased Other Serious 8/2/2010 61 Male 3/1/2011 Physician Japan
Primary
Concomitant
C-reactive Protein Increased Other Serious 6/12/2010 73 Male 3/8/2011 Physician Japan
Primary
Concomitant
Respiratory Distress Hospitalization Male 104 lb 3/10/2011 Physician United States
Primary
Concomitant
Blood Potassium Decreased Hospitalization 6/12/2010 57 Female 3/15/2011 Consumer United States
Primary
Concomitant
Blood Potassium Decreased Hospitalization 7/12/2010 73 Male 134 lb 3/25/2011 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2011 57 Male 4/6/2011 United States
Primary
Concomitant
Interstitial Lung Disease Other Serious 9/2/2010 66 Male 146 lb 4/7/2011 Physician Japan
Primary
Concomitant
Renal Failure Other Serious 9/23/2010 78 Male 4/12/2011 Physician Japan
Primary
Concomitant
Blood Alkaline Phosphatase Increased Hospitalization 6/28/2010 59 Male 4/13/2011 Physician Japan
Primary
Concomitant
Alanine Aminotransferase Increased Hospitalization 10/21/2010 61 Female 4/19/2011 Physician Japan
Primary
Concomitant
Haemoglobin Decreased Other Serious 12/21/2010 75 Male 4/20/2011 Physician Japan
Primary
Secondary
Concomitant
Neoplasm Malignant Disability 7/29/2010 77 Female 110 lb 4/25/2011 Physician Japan
Primary
Concomitant
Haemoglobin Decreased Other Serious 1/19/2011 62 Male 4/27/2011 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 4/15/2011 68 Male 5/2/2011 Physician Japan
Primary
Concomitant
Lymphangiosis Carcinomatosa Hospitalization 9/23/2010 78 Male 5/2/2011 Japan
Primary
Concomitant
Throat Tightness Other Serious Male 5/3/2011 Mexico
Primary
Concomitant
Fluid Retention Hospitalization 1/13/2011 88 Male 4/14/2011 Physician United States
Primary
Concomitant
Neoplasm Malignant Other Serious 2/10/2011 69 Male 5/4/2011 Physician Japan
Primary
Concomitant
Metastases To Bone Hospitalization 6/4/2010 55 Male 154 lb 5/9/2011 Physician Japan
Primary
Concomitant
Generalised Oedema Hospitalization 4/14/2011 82 Male 202 lb 5/10/2011 Consumer United States
Primary
Secondary
Concomitant
Blood Lactate Dehydrogenase Increased Life Threatening 8/16/2010 31 Male 5/19/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 9/2/2010 66 Male 146 lb 5/24/2011 Physician Japan
Primary
Concomitant
Blood Pressure Decreased Hospitalization 11/5/2010 56 Male 5/24/2011 Physician Japan
Primary
Concomitant
Hyperglycaemia Other Serious 9/23/2010 78 Male 5/26/2011 Other Health Professional Japan
Primary
Concomitant
Neoplasm Malignant Hospitalization 8/9/2010 63 Female 5/31/2011 Physician Japan
Primary
Secondary
Concomitant
Infection Other Serious 7/12/2010 73 Male 134 lb 5/26/2011 Physician Japan
Primary
Secondary
Concomitant
Neoplasm Malignant Hospitalization 7/13/2010 58 Male 6/9/2011 Physician Japan
Primary
Concomitant
Haemoglobin Decreased Other Serious 3/25/2010 60 Male 6/14/2011 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 10/19/2010 44 Male 183 lb 6/14/2011 Physician Japan
Primary
Concomitant
Anaemia Life Threatening 7/16/2010 79 Male 130 lb 6/14/2011 Physician Japan
Primary
Concomitant
Acne Other Serious 9/2/2010 66 Male 146 lb 6/20/2011 Physician Japan
Primary
Concomitant
Hyperglycaemia Other Serious 8/16/2010 31 Male 6/24/2011 Physician Japan
Primary
Secondary
Concomitant
Metastases To Bone Death 1/19/2011 62 Male 6/27/2011 Physician Japan
Primary
Concomitant
Hyperglycaemia Other Serious 6/4/2010 55 Male 154 lb 7/19/2011 Physician Japan
Primary
Concomitant
Neoplasm Malignant Hospitalization 2/10/2011 69 Male 7/19/2011 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/8/2011 74 Female 7/27/2011 Consumer United States
Primary
Concomitant
C-reactive Protein Increased Hospitalization 6/3/2011 68 Male 8/8/2011 Physician Japan
Primary
Concomitant
Epilepsy Hospitalization 7/1/2011 59 Female 8/11/2011 Physician Japan
Primary
Concomitant
Depression Other Serious 7/13/2011 56 Male 181 lb 8/18/2011 United States
Primary
Concomitant
Neoplasm Malignant Hospitalization 4/14/2011 58 Female 8/23/2011 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 8/13/2010 65 Female 8/30/2011 Physician Japan
Primary
Secondary
Concomitant
Blood Uric Acid Increased Other Serious 7/29/2010 77 Female 110 lb 8/30/2011 Physician Japan
Primary
Concomitant
Haemoglobin Decreased Hospitalization 6/23/2010 59 Male 9/26/2011 Physician Japan
Primary
Concomitant
Bone Marrow Failure Hospitalization 6/20/2011 71 Male 10/20/2011 Physician Japan
Primary
Concomitant
Neoplasm Progression Other Serious 4/14/2011 58 Female 10/20/2011 Physician Japan
Primary
Concomitant
Renal Failure Other Serious 9/18/2010 77 Male 10/21/2011 Other Health Professional Japan
Primary
Concomitant
Hyperglycaemia Other Serious 5/27/2011 68 Male 10/24/2011 Physician Japan
Primary
Concomitant
Cough Other Serious 9/2/2010 66 Male 146 lb 10/31/2011 Physician Japan
Primary
Concomitant
Metastases To Abdominal Wall Disability 9/17/2010 75 Male 11/2/2011 Physician Japan
Primary
Secondary
Concomitant
Akinesia Hospitalization 8/1/2011 65 Female 11/4/2011 Other Health Professional France
Primary
Concomitant
Renal Failure Other Serious 4/14/2011 58 Female 11/15/2011 Physician Japan
Primary
Concomitant
Neoplasm Progression Hospitalization 8/16/2010 31 Male 11/17/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Bacterial Hospitalization 6/20/2011 71 Male 11/22/2011 Physician Japan
Primary
Concomitant
Malignant Pleural Effusion Hospitalization 8/26/2011 56 Male 130 lb 11/23/2011 Physician Japan
Primary
Concomitant
Convulsion Other Serious Male 12/1/2011 United States
Primary
Concomitant
Neoplasm Progression Hospitalization 5/2/2010 69 Male 12/1/2011 Physician Japan
Primary
Concomitant
Chest X-ray Abnormal Hospitalization 7/13/2010 58 Male 12/5/2011 Physician Japan
Primary
Concomitant
Abdominal Pain Hospitalization 4/2/2010 59 Female 12/6/2011 Physician Japan
Primary
Concomitant
Dizziness Other Serious 7/23/2010 60 Male 123 lb 12/6/2011 Other Health Professional Hong Kong
Primary
Concomitant
Anaemia Hospitalization 7/2/2010 71 Female 104 lb 12/6/2011 Physician Japan
Primary
Secondary
Concomitant
Malignant Pleural Effusion Other Serious 8/26/2011 56 Male 130 lb 12/12/2011 Physician Japan
Primary
Concomitant
Haemoglobin Decreased Death 1/19/2011 62 Male 12/13/2011 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 8/20/2010 76 Male 12/20/2011 Physician Japan
Primary
Secondary
Concomitant

Drug Data