Afinitor combined with Sandostatin Lar

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hypoglycaemia Other Serious 8/27/2009 Female 9/24/2009 Pharmacist United States
Primary
Concomitant
Intestinal Perforation Death 10/15/2009 12/11/2009 Physician United States
Primary
Secondary
Haematuria Hospitalization 11/11/2009 Male 12/17/2009 Physician Netherlands
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 3/20/2009 Female 86 lb 12/23/2009 Physician France
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 9/8/2009 Female 258 lb 12/29/2009 Physician United States
Primary
Secondary
Concomitant
Tongue Oedema Other Serious 71 Female 110 lb 12/31/2009 Physician United States
Primary
Concomitant
Haematuria Hospitalization 11/11/2009 Male 1/7/2010 Physician Netherlands
Primary
Secondary
Concomitant
Gastritis Erosive Hospitalization 4/15/2009 Female 121 lb 1/14/2010 Physician Germany
Primary
Secondary
Concomitant
Pruritus Disability 10/3/2009 Male 1/25/2010 Physician United Kingdom
Primary
Concomitant
Nausea Life Threatening 1/26/2010 Female 146 lb 2/7/2010 Physician United States
Primary
Secondary
Nausea Life Threatening 1/26/2010 Female 146 lb 2/17/2010 Physician United States
Primary
Secondary
Nausea Life Threatening 1/26/2010 Female 146 lb 2/24/2010 Physician United States
Primary
Secondary
Pruritus Disability 10/27/2009 Male 3/2/2010 Physician United Kingdom
Primary
Concomitant
Dyspnoea Hospitalization 3/4/2010 Female 115 lb 3/16/2010 Physician United States
Primary
Secondary
Metastatic Carcinoid Tumour Hospitalization 4/13/2010 52 Male 139 lb 4/21/2010 Physician Sweden
Primary
Secondary
Concomitant
Cerebral Haemorrhage Death Male 4/26/2010 Physician India
Primary
Secondary
Pneumonitis Other Serious 1/7/2008 81 Female 136 lb 4/30/2010 Physician United States
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 4/28/2010 74 Male 5/13/2010 Physician Netherlands
Primary
Secondary
Concomitant
Urticaria Hospitalization 4/15/2010 61 Male 145 lb 5/20/2010 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 9/15/2008 36 Female 146 lb 5/28/2010 United States
Primary
Secondary
Urticaria Hospitalization 4/15/2010 61 Male 145 lb 5/28/2010 Physician United States
Primary
Secondary
Concomitant
Pneumonitis Other Serious 1/7/2008 81 Female 136 lb 6/1/2010 Physician United States
Primary
Secondary
Concomitant
Non-cardiac Chest Pain Hospitalization 1/28/2008 68 Female 152 lb 6/15/2010 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 8/19/2008 54 Female 6/25/2010 Physician Netherlands
Primary
Concomitant
Blood Bilirubin Increased Hospitalization 4/13/2010 52 Male 139 lb 6/28/2010 Physician Sweden
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 4/28/2010 74 Male 7/23/2010 Physician Netherlands
Primary
Secondary
Concomitant
Vomiting Other Serious 69 Male 7/27/2010 Physician India
Primary
Secondary
Urticaria Hospitalization 4/15/2010 61 Male 145 lb 8/4/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 69 Male 8/13/2010 Physician India
Primary
Secondary
Coronary Artery Insufficiency Life Threatening 5/21/2010 68 Female 138 lb 9/8/2010 Physician Germany
Primary
Secondary
Concomitant
Concomitant Disease Progression Life Threatening 5/21/2010 68 Female 138 lb 9/16/2010 Physician Germany
Primary
Secondary
Concomitant
Subileus Hospitalization 8/29/2010 74 Male 110 lb 9/24/2010 Physician Italy
Primary
Secondary
Pyrexia Hospitalization 10/13/2010 71 Female 183 lb 10/22/2010 Physician Netherlands
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Other Serious 6/10/2010 52 Male 176 lb 11/16/2010 Physician France
Primary
Secondary
Concomitant
Blood Bilirubin Increased Hospitalization 4/13/2010 52 Male 139 lb 11/22/2010 Physician Sweden
Primary
Secondary
Concomitant
Paracentesis Other Serious Female 12/8/2010 Canada
Primary
Secondary
Tongue Ulceration Other Serious Male 12/9/2010 Canada
Primary
Secondary
Paracentesis Other Serious Female 12/13/2010 Canada
Primary
Secondary
Drug Ineffective Hospitalization 5/15/2008 64 Female 154 lb 1/3/2011 Physician Italy
Primary
Secondary
Blood Lactate Dehydrogenase Increased Other Serious 5/22/2008 75 Male 1/3/2011 Physician Spain
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 1/29/2008 59 Male 179 lb 1/3/2011 Physician Germany
Primary
Secondary
Dyspnoea Hospitalization 10/1/2008 23 Female 161 lb 1/3/2011 Physician France
Primary
Secondary
Nausea Hospitalization 11/19/2007 59 Female 126 lb 1/3/2011 Physician Germany
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 3/1/2008 71 126 lb 1/3/2011 Physician Israel
Primary
Secondary
Hyperthermia Hospitalization 2/29/2008 75 Male 1/3/2011 Physician France
Primary
Secondary
Troponin Increased Hospitalization 2/21/2008 67 Male 381 lb 1/3/2011 Physician United States
Primary
Secondary
Hypocalcaemia Hospitalization 4/11/2008 60 Male 1/3/2011 Physician Netherlands
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 7/2/2008 66 Male 209 lb 1/3/2011 United States
Primary
Secondary
Pericardial Excision Hospitalization 11/1/2008 68 Male 182 lb 1/3/2011 Physician United States
Primary
Concomitant
Faeces Discoloured Hospitalization 10/8/2008 60 Male 186 lb 1/3/2011 Physician United States
Primary
Concomitant
Hypertension Disability 12/30/2007 54 Female 132 lb 1/3/2011 Physician Turkey
Primary
Secondary
Concomitant
Nausea Hospitalization 6/7/2008 50 Female 1/3/2011 Physician United States
Primary
Secondary
Diarrhoea Hospitalization 5/9/2008 67 Female 156 lb 1/3/2011 Consumer United States
Primary
Secondary
Concomitant
Hyperglycaemia Hospitalization 10/16/2008 55 Female 130 lb 1/3/2011 Physician Turkey
Primary
Concomitant
Asthenia Hospitalization 4/22/2008 68 Male 1/3/2011 Physician United States
Primary
Secondary
Concomitant
Cough Disability 10/16/2008 55 Female 130 lb 1/3/2011 Physician Turkey
Primary
Concomitant
Multi-organ Failure Hospitalization 7/24/2008 74 Female 134 lb 1/3/2011 Physician United States
Primary
Secondary
Dyspnoea Hospitalization 3/4/2010 64 Female 115 lb 1/3/2011 Physician United States
Primary
Secondary
Lung Infiltration Hospitalization 6/12/2008 71 Male 185 lb 1/3/2011 Physician United States
Primary
Secondary
Concomitant
Non-cardiac Chest Pain Hospitalization 1/28/2008 68 Female 152 lb 1/3/2011 Physician United States
Primary
Secondary
Concomitant
Chest Pain Hospitalization 9/15/2008 36 Female 146 lb 1/3/2011 United States
Primary
Secondary
Malaise Other Serious Female 1/10/2011 Other Health Professional Canada
Primary
Secondary
Anaemia Hospitalization 12/22/2010 56 Male 176 lb 1/12/2011 Physician Spain
Primary
Secondary
Vomiting Death 69 Male 1/19/2011 Physician India
Primary
Secondary
Anaemia Death 12/22/2010 56 Male 176 lb 1/26/2011 Physician Spain
Primary
Secondary
Concomitant
Oral Pain Other Serious 1/20/2011 79 Male 2/4/2011 Other Health Professional Canada
Primary
Secondary
Pleural Effusion Other Serious 1/1/2011 Female 2/7/2011 Physician Germany
Primary
Concomitant
Hypophagia Hospitalization 12/7/2010 54 Female 2/14/2011 Consumer United States
Primary
Secondary
Concomitant
Heart Rate Increased Other Serious Female 2/15/2011 Canada
Primary
Secondary
Palliative Care Other Serious 2/12/2011 76 Female 2/18/2011 Canada
Primary
Secondary
Metastases To Lymph Nodes Other Serious 6/1/2006 63 Female 2/28/2011 Physician Finland
Primary
Concomitant
Platelet Count Decreased Other Serious Male 3/22/2011 Consumer Canada
Primary
Secondary
Erythema Other Serious Female 4/8/2011 Consumer Canada
Primary
Secondary
Bile Duct Obstruction Hospitalization 3/29/2011 48 Male 4/12/2011 Consumer Canada
Primary
Secondary
Fatigue Other Serious Female 4/13/2011 Canada
Primary
Secondary
Diarrhoea Hospitalization Female 4/19/2011 Consumer Canada
Primary
Secondary
Chills Other Serious 3/18/2011 62 Female 4/19/2011 Canada
Primary
Secondary
Feeling Abnormal Other Serious Female 4/20/2011 Consumer Canada
Primary
Secondary
Liver Function Test Abnormal Other Serious 1/27/2011 55 Male 154 lb 4/25/2011 United States
Primary
Concomitant
Malaise Hospitalization Female 4/28/2011 Other Health Professional Canada
Primary
Secondary
Fatigue Other Serious 1/20/2011 79 Male 4/18/2011 Physician Canada
Primary
Secondary
Lung Infection Other Serious 3/18/2011 62 Female 5/4/2011 Consumer Canada
Primary
Secondary
Vomiting Other Serious 3/27/2011 62 Male 185 lb 5/9/2011 Physician United States
Primary
Secondary
Concomitant
Blood Pressure Increased Other Serious Male 5/19/2011 Consumer Canada
Primary
Secondary
Lung Infection Other Serious 3/18/2011 62 Female 5/20/2011 Canada
Primary
Secondary
Fatigue Other Serious Female 5/20/2011 Canada
Primary
Secondary
Platelet Count Decreased Other Serious Male 5/31/2011 Consumer Canada
Primary
Secondary
Nasopharyngitis Other Serious Female 5/31/2011 Canada
Primary
Secondary
Nail Disorder Other Serious 2/1/2011 70 Female 6/3/2011 Canada
Primary
Secondary
Sudden Death Death 4/22/2011 67 Male 187 lb 6/3/2011 Physician United States
Primary
Concomitant
Asthenia Hospitalization Female 5/25/2011 Other Health Professional Canada
Primary
Secondary
Head Discomfort Other Serious Male 6/10/2011 Canada
Primary
Secondary
Chills Other Serious Female 6/10/2011 Consumer Canada
Primary
Secondary
Death Death 5/4/2011 52 Male 6/13/2011 Consumer Canada
Primary
Secondary
Stomatitis Other Serious Male 6/14/2011 Canada
Primary
Secondary
Sudden Death Death 4/22/2011 67 Male 187 lb 6/14/2011 Physician United States
Primary
Concomitant
Decreased Appetite Other Serious Male 6/15/2011 Canada
Primary
Secondary
Neoplasm Malignant Death 5/4/2011 52 Male 6/16/2011 Consumer Canada
Primary
Secondary
Abdominal Pain Upper Hospitalization 5/26/2011 56 Male 6/16/2011 Consumer Canada
Primary
Secondary
Chills Other Serious Female 6/20/2011 Other Health Professional Canada
Primary
Secondary
Pancytopenia Death 4/13/2011 80 Female 6/20/2011 Physician Germany
Primary
Concomitant
Diarrhoea Other Serious Female 6/22/2011 Canada
Primary
Secondary
Stress Other Serious Female 6/24/2011 Canada
Primary
Secondary
Tongue Ulceration Other Serious 1/20/2011 79 Male 6/28/2011 Pharmacist Canada
Primary
Secondary
Dyspnoea Hospitalization Female 6/28/2011 Canada
Primary
Secondary
Paracentesis Hospitalization Female 6/28/2011 Other Health Professional Canada
Primary
Secondary
Weight Decreased Other Serious Male 143 lb 6/23/2011 Germany
Primary
Concomitant
Heart Rate Increased Other Serious Female 6/30/2011 Canada
Primary
Secondary
Abdominal Pain Other Serious Female 7/1/2011 Other Health Professional Canada
Primary
Secondary
Feeling Abnormal Life Threatening Male 7/1/2011 Consumer Canada
Primary
Secondary
Nasal Dryness Other Serious 2/1/2011 70 Female 7/1/2011 Physician Canada
Primary
Secondary
Hypophagia Other Serious Male 7/8/2011 Consumer Canada
Primary
Secondary
Abdominal Pain Other Serious Female 7/13/2011 Physician Canada
Primary
Secondary
Metastatic Carcinoid Tumour Other Serious 6/28/2011 Physician United States
Primary
Secondary
Fatigue Life Threatening 6/15/2011 62 Female 7/15/2011 Canada
Primary
Secondary
Anger Other Serious Male 7/19/2011 Consumer Canada
Primary
Secondary
Anger Other Serious Male 7/21/2011 Canada
Primary
Secondary
Small Intestinal Obstruction Hospitalization 7/3/2011 78 Male 7/28/2011 Physician United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 6/30/2011 49 143 lb 7/28/2011 Physician United States
Primary
Secondary
Asthenia Other Serious 5/17/2011 71 Male 8/5/2011 Consumer Canada
Primary
Secondary
Concomitant
Asthenia Other Serious 7/22/2011 49 Female 8/8/2011 Consumer Canada
Primary
Secondary
Malaise Other Serious 7/22/2011 49 Female 8/10/2011 Consumer Canada
Primary
Secondary
Renal Failure Other Serious Male 8/16/2011 Canada
Primary
Secondary
Lethargy Other Serious Female 8/17/2011 Physician Canada
Primary
Secondary
Neoplasm Malignant Hospitalization 78 Female 8/19/2011 Physician Israel
Primary
Concomitant
Neoplasm Malignant Death 6/1/2011 78 Female 8/19/2011 Israel
Primary
Concomitant
Mouth Ulceration Other Serious 1/20/2011 79 Male 8/19/2011 Physician Canada
Primary
Secondary
Small Intestinal Obstruction Hospitalization 7/3/2011 78 Male 145 lb 8/20/2011 Physician United States
Primary
Secondary
Concomitant
Ascites Hospitalization 1/1/2011 Female 176 lb 8/25/2011 Physician Germany
Primary
Secondary
Concomitant
Neoplasm Progression Death 8/3/2011 60 Female 8/26/2011 Consumer Colombia
Primary
Secondary
Concomitant
Heart Rate Increased Other Serious Female 8/26/2011 Other Health Professional Canada
Primary
Secondary
Diarrhoea Other Serious Female 8/31/2011 Canada
Primary
Secondary
Concomitant
Fatigue Other Serious Female 9/1/2011 Canada
Primary
Secondary
Death Death Female 9/2/2011 Other Health Professional Canada
Primary
Secondary
Low Density Lipoprotein Decreased Other Serious Male 9/6/2011 Canada
Primary
Secondary
Abscess Other Serious Female 9/8/2011 Canada
Primary
Secondary
Hypertension Death 8/31/2011 71 Female 9/9/2011 Canada
Primary
Secondary
Diarrhoea Other Serious Female 9/13/2011 Other Health Professional Canada
Primary
Secondary
Metastases To Bone Hospitalization Male 9/19/2011 Physician Canada
Primary
Secondary
Thrombocytopenia Other Serious 8/8/2011 67 Female 9/23/2011 Physician France
Primary
Secondary
Blood Pressure Increased Hospitalization Female 9/26/2011 Canada
Primary
Secondary
Concomitant
Diarrhoea Other Serious Female 9/30/2011 Consumer Canada
Primary
Secondary
Concomitant Disease Progression Hospitalization 9/23/2011 59 Male 143 lb 10/6/2011 Physician Lebanon
Primary
Concomitant
Purpura Other Serious 7/10/2011 68 Female 10/10/2011 Physician France
Primary
Secondary
Asthenia Other Serious Female 10/11/2011 Consumer Canada
Primary
Secondary
Rash Maculo-papular Other Serious Male 10/11/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Stomatitis Hospitalization Female 10/14/2011 United States
Primary
Secondary
Neoplasm Malignant Death 8/3/2011 60 Female 10/17/2011 Consumer Colombia
Primary
Secondary
Concomitant
Weight Decreased Other Serious Male 10/18/2011 United States
Primary
Secondary
Abdominal Pain Upper Other Serious Female 10/19/2011 Canada
Primary
Secondary
Concomitant

Drug Data