Bortezomib



Indications and Reactions:

Role Indications Reactions
Primary
Multiple Myeloma 22.4%
Mantle Cell Lymphoma 17.1%
Diffuse Large B-cell Lymphoma 10.0%
Acute Myeloid Leukaemia 9.4%
B-cell Lymphoma 4.7%
Neuroblastoma 4.1%
Non-small Cell Lung Cancer 4.1%
Acute Lymphocytic Leukaemia 3.5%
Small Cell Lymphocytic Lymphoma 3.5%
B-cell Lymphoma Recurrent 2.4%
Chronic Lymphocytic Leukaemia 2.4%
Diffuse Large B-cell Lymphoma Recurrent 2.4%
Renal Cell Carcinoma 2.4%
Renal Cell Carcinoma Stage Unspecified 2.4%
Acute Lymphocytic Leukaemia Recurrent 1.8%
Graft Versus Host Disease 1.8%
Non-hodgkin's Lymphoma 1.8%
Product Used For Unknown Indication 1.8%
Non-hodgkin's Lymphoma Recurrent 1.2%
Pharyngeal Cancer Recurrent 1.2%
Vomiting 21.0%
Thrombocytopenia 12.9%
Pyrexia 9.7%
Herpes Zoster 4.8%
Nausea 4.8%
Streptococcus Test Positive 4.8%
Diarrhoea 3.2%
Neuropathy Peripheral 3.2%
Pain In Extremity 3.2%
Peripheral Sensorimotor Neuropathy 3.2%
Pleural Effusion 3.2%
Pseudomonal Sepsis 3.2%
Respiratory Failure 3.2%
Staphylococcal Infection 3.2%
Syncope 3.2%
Tachycardia 3.2%
Unresponsive To Stimuli 3.2%
White Blood Cell Count Increased 3.2%
Abdominal Discomfort 1.6%
Anaemia 1.6%
Secondary
Multiple Myeloma 38.9%
Plasma Cell Myeloma 13.7%
Product Used For Unknown Indication 11.3%
Prophylaxis 5.2%
Drug Use For Unknown Indication 4.5%
Mantle Cell Lymphoma 4.3%
Acute Lymphocytic Leukaemia 4.1%
Infection Prophylaxis 2.4%
Non-hodgkin's Lymphoma 2.2%
Pain 2.0%
Diffuse Large B-cell Lymphoma 1.9%
B-cell Lymphoma 1.8%
Thrombosis Prophylaxis 1.6%
Hypertension 1.3%
Acute Myeloid Leukaemia 0.9%
Nausea 0.8%
Waldenstrom's Macroglobulinaemia 0.8%
Amyloidosis 0.8%
Leukaemia Plasmacytic 0.8%
Antiviral Prophylaxis 0.7%
Thrombocytopenia 16.9%
Neuropathy Peripheral 9.4%
Vomiting 8.1%
Pyrexia 7.8%
Gastrointestinal Inflammation 6.6%
Pneumonia 6.0%
Sepsis 5.9%
Febrile Neutropenia 3.8%
Platelet Count Decreased 3.5%
Syncope 3.5%
Neutropenia 3.4%
Neurotoxicity 3.2%
Pulmonary Embolism 3.1%
White Blood Cell Count Decreased 3.1%
Nausea 2.8%
Septic Shock 2.8%
Bronchiolitis 2.7%
Renal Failure 2.7%
Lung Disorder 2.5%
Death 2.4%
Concomitant
Multiple Myeloma 30.4%
Product Used For Unknown Indication 18.7%
Plasma Cell Myeloma 16.6%
Drug Use For Unknown Indication 15.6%
Prophylaxis 2.3%
Mantle Cell Lymphoma 2.0%
Plasmacytoma 1.8%
Prophylaxis Against Transplant Rejection 1.7%
Thrombosis Prophylaxis 1.6%
Pain 1.5%
Myeloma Recurrence 1.0%
Chemotherapy 1.0%
Disease Progression 0.9%
Metastases To Bone 0.9%
Neoplasm Malignant 0.8%
Pyrexia 0.8%
Plasma Cell Myeloma Recurrent 0.8%
Hypertension 0.7%
Amyloidosis 0.6%
Immunosuppression 0.5%
Unevaluable Event 13.4%
Toxicity To Various Agents 10.0%
Thrombocytopenia 9.7%
Vomiting 9.4%
Plasma Cell Myeloma 6.7%
Multiple Myeloma 6.0%
Osteonecrosis 5.7%
Renal Failure Acute 4.0%
Pneumonia 3.7%
Pulmonary Embolism 3.7%
Neuropathy Peripheral 3.3%
Renal Failure 3.3%
Adverse Drug Reaction 3.0%
Death 2.7%
Purulent Discharge 2.7%
Pyrexia 2.7%
Tooth Extraction 2.7%
Tumour Lysis Syndrome 2.7%
Osteonecrosis Of Jaw 2.3%
Pancytopenia 2.3%
Interacting
Product Used For Unknown Indication 37.3%
Multiple Myeloma 29.4%
Infection Prophylaxis 9.8%
Plasma Cell Myeloma 7.8%
Fungal Infection 5.9%
Pyrexia 3.9%
Antifungal Prophylaxis 2.0%
Prophylaxis 2.0%
Prostatitis 2.0%
Tubulointerstitial Nephritis 45.5%
Thrombocytopenia 27.3%
Ileus Paralytic 13.6%
Neuropathy Peripheral 4.5%
Syncope 4.5%
Urinary Retention 4.5%