Bortezomib combined with Doxorubicin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Thrombocytopenia Other Serious 60 Male 7/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Thrombocytopenia Other Serious 12/3/2009 Consumer United Kingdom
Primary
Secondary
Septic Shock Other Serious 12/10/2009 Israel
Primary
Concomitant
Osteonecrosis Other Serious 10/1/2009 Male 160 lb 2/17/2010 Physician United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 57 Female 3/8/2010 Other Health Professional Poland
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 3/11/2010 Other Health Professional Greece
Primary
Secondary
Stem Cell Transplant Hospitalization 65 Male 3/18/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 7/6/2010 45 Female 9/27/2010 Australia
Primary
Secondary
Infection Other Serious 11/4/2010 Physician United States
Primary
Secondary
Lung Infection Other Serious 3/1/2007 53 Male 11/11/2010 Consumer Germany
Primary
Concomitant
Arrhythmia Other Serious 12/21/2010 Physician United States
Primary
Secondary
Concomitant
Hypercalcaemia Hospitalization 67 Male 132 lb 1/3/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Lymphopenia Other Serious 1/17/2011 Physician United States
Primary
Secondary
Concomitant
Hypoalbuminaemia Other Serious 1/17/2011 Physician United States
Primary
Secondary
Concomitant
Multiple Myeloma Death 1/1/2010 42 Male 1/17/2011 Physician Switzerland
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 55 1/28/2011 Other Health Professional United States
Primary
Secondary
Chills Hospitalization 1/25/2011 60 Male 1/28/2011 Other Health Professional United States
Primary
Secondary
Neutropenia Other Serious Male 2/11/2011 Physician United Kingdom
Primary
Secondary
Haemochromatosis Other Serious 67 Male 132 lb 2/24/2011 Physician Japan
Primary
Secondary
Humerus Fracture Other Serious 45 Female 3/3/2011 Physician United States
Primary
Concomitant
Bradycardia Other Serious 3/11/2011 Physician United States
Primary
Secondary
Hyperuricaemia Other Serious 3/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Confusional State Other Serious 3/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Arrhythmia Other Serious 3/11/2011 Physician United States
Primary
Secondary
Concomitant
Lymphopenia Other Serious 3/11/2011 Physician United States
Primary
Secondary
Concomitant
Hypoalbuminaemia Other Serious 3/11/2011 Physician United States
Primary
Secondary
Concomitant
Bacteraemia Other Serious 3/11/2011 Other Health Professional United States
Primary
Secondary
Atrial Fibrillation Hospitalization 2/18/2011 70 Male 127 lb 3/15/2011 Other Health Professional United Kingdom
Primary
Secondary
Atrial Fibrillation Hospitalization 2/18/2011 70 Male 127 lb 3/22/2011 Other Health Professional United Kingdom
Primary
Secondary
Atrial Fibrillation Hospitalization 2/18/2011 70 Male 127 lb 3/24/2011 Other Health Professional United Kingdom
Primary
Secondary
Humerus Fracture Other Serious 45 Female 3/30/2011 Physician United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 2/18/2011 70 Male 127 lb 4/1/2011 Other Health Professional United Kingdom
Primary
Secondary
Pleural Effusion Other Serious 4/1/2011 Consumer United Kingdom
Primary
Secondary
Lung Infection Other Serious 3/1/2007 53 Male 4/5/2011 Consumer Germany
Primary
Concomitant
Peripheral Sensorimotor Neuropathy Hospitalization 12/26/2010 21 Male 127 lb 3/29/2011 Physician United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 2/18/2011 70 Male 127 lb 4/13/2011 Other Health Professional United Kingdom
Primary
Secondary
Squamous Cell Carcinoma Of Skin Other Serious 7/2011 Male 9/14/2012 Physician Dk
Primary
Secondary
Concomitant
Pneumonia Death NotSpecified 8/20/2013 Physician Jp
Primary
Secondary
Hepatic Enzyme Increased Other Serious NotSpecified 8/26/2013 Physician Jp
Primary
Secondary
Toxicity To Various Agents Other Serious NotSpecified 8/26/2013 Physician Jp
Primary
Secondary
Renal Failure Acute Other Serious 6/3/2012 57 Female 158 lb 9/24/2012 Physician Us
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Death 11/7/2011 56 Male 198 lb 5/28/2013 Other Health Professional Dk
Primary
Secondary
Concomitant
Pleural Effusion Death 11/23/2012 Physician Us
Primary
Secondary
Sepsis Death 12/31/2012 Physician Us
Primary
Secondary
Off Label Use Other Serious 12/14/2012 Physician Us
Primary
Secondary
Off Label Use Other Serious 11/23/2012 Physician Us
Primary
Secondary
Neutropenic Sepsis Death 8/31/2012 59 Female 163 lb 9/18/2012 Other Health Professional Hu
Primary
Secondary
Concomitant
Infection Other Serious 10/30/2012 Country Not Specified
Primary
Secondary
Concomitant
Small Intestinal Perforation Other Serious 10/30/2012 Country Not Specified
Primary
Secondary
Concomitant
Septic Shock Death 10/30/2012 Country Not Specified
Primary
Secondary
Concomitant
Septic Shock Other Serious 10/30/2012 Country Not Specified
Primary
Secondary
Concomitant
Delirium Other Serious 10/30/2012 Country Not Specified
Primary
Secondary
Concomitant
Hepatic Failure Death 44 Male 12/6/2012 Country Not Specified
Primary
Secondary
Sepsis Death 65 Male 12/6/2012 Country Not Specified
Primary
Secondary
Herpes Zoster Other Serious 61 Female 12/6/2012 Country Not Specified
Primary
Secondary
Pneumocystis Jiroveci Pneumonia Other Serious 56 Female 12/6/2012 Country Not Specified
Primary
Secondary
Vomiting Hospitalization 11/22/2012 37 Female 148 lb 1/4/2013 Physician Us
Primary
Secondary
Concomitant
Zygomycosis Death 54 Male 12/19/2012 De
Primary
Secondary
Thrombocytopenia Death 1/3/2013 70 Male 264 lb 1/8/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious NotSpecified 1/14/2014 Other Health Professional It
Primary
Concomitant
Infection Other Serious NotSpecified 1/29/2013 Other Health Professional Us
Primary
Secondary
Mallory-weiss Syndrome Other Serious NotSpecified 1/29/2013 Other Health Professional Us
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious NotSpecified 1/29/2013 Other Health Professional Us
Primary
Secondary
Urinary Tract Infection Other Serious NotSpecified 1/29/2013 Other Health Professional Us
Primary
Secondary
Pulmonary Embolism Death NotSpecified 1/29/2013 Other Health Professional Us
Primary
Secondary
Cytogenetic Abnormality Other Serious 79 Male 7/12/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious NotSpecified 1/29/2013 Other Health Professional Us
Primary
Secondary
Plasma Cell Myeloma Other Serious 46 NotSpecified 2/7/2013 Other Health Professional Au
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 9/18/2009 53 Male 2/13/2013 Other Health Professional Gb
Primary
Concomitant
Cardio-respiratory Arrest Death 12/25/2012 65 Female 193 lb 2/26/2013 Consumer Us
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 58 Male 2/27/2013 Other Health Professional Us
Primary
Secondary
Alanine Aminotransferase Increased Other Serious NotSpecified 5/24/2013 Other Health Professional Country Not Specified
Primary
Secondary
Toxicity To Various Agents Other Serious NotSpecified 4/15/2013 Physician Us
Primary
Secondary
Toxicity To Various Agents Other Serious NotSpecified 4/15/2013 Physician Us
Primary
Secondary
Toxicity To Various Agents Other Serious NotSpecified 4/15/2013 Physician Us
Primary
Secondary
Toxicity To Various Agents Other Serious NotSpecified 4/15/2013 Physician Us
Primary
Secondary
Plasma Cell Myeloma Life Threatening 11/15/2012 74 Male 177 lb 5/29/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Thrombocytopenia Death NotSpecified 4/19/2013 Other Health Professional It
Primary
Secondary
Staphylococcal Infection Hospitalization 64 Female 5/6/2013 Other Health Professional Tr
Primary
Secondary
Concomitant
Off Label Use Other Serious 13 Male 5/6/2013 Physician Us
Primary
Secondary
Vomiting Death NotSpecified 5/6/2013 Other Health Professional Cn
Primary
Secondary
Concomitant
Death Death NotSpecified 5/17/2013 Other Health Professional Cn
Primary
Secondary
Concomitant
Syncope Hospitalization 4/8/2013 72 Female 174 lb 5/7/2013 Physician Us
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 53 Male 5/9/2013 Physician Np
Primary
Secondary
Off Label Use Other Serious 6/29/2010 50 Male 165 lb 5/28/2013 Physician Pt
Primary
Secondary
Concomitant
Tachycardia Required Intervention 5/22/2013 82 NotSpecified 5/24/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Tachycardia Required Intervention 5/22/2013 82 Female 199 lb 5/28/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Heart Rate Increased Hospitalization 5/23/2013 56 Male 348 lb 5/28/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Poems Syndrome Death NotSpecified 7/19/2013 Other Health Professional Cz
Primary
Secondary
Peripheral Sensory Neuropathy Other Serious 57 Female 6/10/2013 Physician Pl
Primary
Secondary
Urinary Tract Infection Hospitalization 5/31/2013 67 Female 7/24/2013 Physician Gb
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 5/31/2013 67 Female 7/26/2013 Physician Gb
Primary
Secondary
Concomitant
Nausea Hospitalization 6/18/2013 65 Female 136 lb 6/20/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 3/7/2013 77 Male 212 lb 8/5/2013 Physician Us
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 5/31/2013 67 Female 8/7/2013 Physician Gb
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 5/31/2013 67 Female 7/30/2013 Physician Gb
Primary
Secondary
Concomitant
Nephropathy Toxic Other Serious NotSpecified 7/24/2013 Physician Us
Primary
Secondary
Off Label Use Death NotSpecified 7/19/2013 Other Health Professional Us
Primary
Secondary
Procedural Haemorrhage Death NotSpecified 7/25/2013 Physician Us
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious NotSpecified 7/25/2013 Physician Us
Primary
Secondary
Concomitant
Neutropenic Infection Other Serious NotSpecified 7/26/2013 Physician Us
Primary
Secondary
Concomitant
Confusional State Life Threatening NotSpecified 7/26/2013 Physician Us
Primary
Secondary
Concomitant
Hypertriglyceridaemia Life Threatening NotSpecified 7/26/2013 Physician Us
Primary
Secondary
Concomitant
Hypomagnesaemia Other Serious NotSpecified 7/26/2013 Physician Us
Primary
Secondary
Concomitant
Hepatic Function Abnormal Life Threatening NotSpecified 7/26/2013 Physician Us
Primary
Secondary
Concomitant
Troponin I Other Serious NotSpecified 7/26/2013 Us
Primary
Secondary
Concomitant
Blood Bicarbonate Decreased Other Serious NotSpecified 7/29/2013 Physician Us
Primary
Secondary
Concomitant
Troponin I Increased Other Serious NotSpecified 7/29/2013 Physician Us
Primary
Secondary
Concomitant
Renal Failure Other Serious NotSpecified 7/29/2013 Physician Us
Primary
Secondary
Concomitant
Arthropathy Other Serious NotSpecified 7/29/2013 Physician Us
Primary
Secondary
Concomitant
Neutropenic Infection Death NotSpecified 7/29/2013 Physician Us
Primary
Secondary
Concomitant
Renal Failure Life Threatening NotSpecified 7/29/2013 Physician Us
Primary
Secondary
Concomitant
Blood Cholesterol Abnormal Other Serious NotSpecified 7/29/2013 Physician Us
Primary
Secondary
Concomitant
Lung Infection Other Serious NotSpecified 7/29/2013 Physician Us
Primary
Secondary
Concomitant
Gastrointestinal Disorder Other Serious NotSpecified 7/29/2013 Physician Us
Primary
Secondary
Concomitant
Hearing Impaired Other Serious NotSpecified 7/29/2013 Physician Us
Primary
Secondary
Concomitant
Skin Disorder Other Serious NotSpecified 7/29/2013 Physician Us
Primary
Secondary
Concomitant
Rectal Haemorrhage Life Threatening NotSpecified 7/29/2013 Physician Us
Primary
Secondary
Concomitant
Cognitive Disorder Other Serious NotSpecified 7/29/2013 Physician Us
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Other Serious NotSpecified 7/29/2013 Physician Us
Primary
Secondary
Concomitant
Memory Impairment Other Serious NotSpecified 7/29/2013 Physician Us
Primary
Secondary
Concomitant
Mental Disorder Other Serious NotSpecified 7/29/2013 Physician Us
Primary
Secondary
Concomitant
Musculoskeletal Disorder Other Serious NotSpecified 7/29/2013 Physician Us
Primary
Secondary
Concomitant
Nervous System Disorder Other Serious NotSpecified 7/29/2013 Physician Us
Primary
Secondary
Concomitant
Opportunistic Infection Other Serious NotSpecified 9/4/2013 Physician Us
Primary
Secondary
Concomitant
Pain Other Serious NotSpecified 7/29/2013 Physician Us
Primary
Secondary
Concomitant
Pneumonitis Other Serious NotSpecified 7/29/2013 Physician Us
Primary
Secondary
Concomitant
Haemorrhage Death NotSpecified 7/29/2013 Physician Us
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious NotSpecified 7/29/2013 Physician Us
Primary
Secondary
Concomitant
Haemorrhage Life Threatening NotSpecified 7/29/2013 Physician Us
Primary
Secondary
Concomitant
Vomiting Hospitalization NotSpecified 9/6/2013 Physician Us
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious NotSpecified 8/7/2013 Physician Us
Primary
Secondary
Pulmonary Congestion Hospitalization 8/5/2013 71 Male 115 lb 8/6/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Vomiting Other Serious 50 Male 8/13/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious NotSpecified 9/11/2013 Other Health Professional Be
Primary
Secondary
Peripheral Sensory Neuropathy Other Serious NotSpecified 10/10/2013 Other Health Professional Gb
Primary
Secondary
Vitreous Floaters Other Serious 67 Female 9/13/2013 Other Health Professional Au
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/17/2013 80 Female 10/7/2013 Physician Gb
Primary
Secondary
Concomitant
Vomiting Life Threatening 9/17/2013 80 Female 12/18/2013 Physician Gb
Primary
Secondary
Concomitant
Vomiting Other Serious 9/17/2013 80 Female 12/17/2013 Physician Gb
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/17/2013 80 Female 10/22/2013 Physician Gb
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/17/2013 80 Female 10/14/2013 Physician Gb
Primary
Secondary
Concomitant
Vomiting Life Threatening 9/17/2013 80 Female 12/18/2013 Physician Gb
Primary
Secondary
Concomitant
Splenic Infarction Hospitalization 9/27/2013 56 Male 4/22/2014 Physician Us
Primary
Secondary
Off Label Use Other Serious 6/29/2010 Male 165 lb 10/31/2013 Pharmacist Pt
Primary
Secondary
Concomitant
Cytomegalovirus Infection Death NotSpecified 12/2/2013 Physician It
Primary
Secondary
Upper Respiratory Tract Infection Hospitalization 11/7/2013 61 Female 133 lb 12/5/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 10/7/2013 23 Male 214 lb 10/25/2013 Us
Primary
Concomitant
Plasmablastic Lymphoma Death 44 Female 12/6/2013 Other Health Professional Us
Primary
Secondary
Tumour Lysis Syndrome Life Threatening 45 Male 12/20/2013 Physician Ru
Primary
Secondary
Concomitant

Drug Data