Bortezomib combined with Dexamethasone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pain Other Serious 11/1/2005 48 4/6/2007 Spain
Primary
Concomitant
Pain Other Serious 11/1/2005 48 Male 4/13/2007 Spain
Primary
Secondary
Pulmonary Embolism Other Serious 12/26/2007 54 Male 192 lb 12/27/2007 Other Health Professional United States
Primary
Secondary
Embolism Other Serious 2/1/2008 48 Male 282 lb 2/7/2008 Other Health Professional United States
Primary
Secondary
Respiratory Failure Life Threatening 1/29/2008 78 Male 172 lb 4/4/2008 Physician Italy
Primary
Secondary
Concomitant
Haemorrhage Other Serious 4/7/2008 Other Health Professional Italy
Primary
Secondary
Pyrexia Other Serious 5/19/2008 74 Male 167 lb 5/19/2008 Other Health Professional United States
Primary
Secondary
White Blood Cell Count Increased Hospitalization 6/26/2008 59 Male 198 lb 7/1/2008 Other Health Professional United States
Primary
Secondary
Cardiac Failure Acute Death 8/22/2006 79 Female 7/25/2008 Physician Italy
Primary
Secondary
Concomitant
Osteonecrosis Life Threatening 6/20/2008 Female 8/11/2008 Other Health Professional Italy
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 1/1/2006 62 Female 9/26/2008
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 2/8/2008 Male 154 lb 10/13/2008 Physician United States
Primary
Secondary
Hyperglycaemia Hospitalization 1/14/2008 Male 338 lb 10/13/2008 Physician United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 7/31/2008 8 Female 71 lb 10/30/2008 Physician United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 1/1/2008 63 Female 11/7/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Hospitalization 62 Female 12/2/2008 Other Health Professional China
Primary
Concomitant
Neuropathy Peripheral Other Serious 68 Female 12/15/2008 Other Health Professional United Kingdom
Primary
Secondary
Sleep Disorder Other Serious Female 12/15/2008 Other Health Professional United Kingdom
Primary
Secondary
Neuropathy Peripheral 68 Female 12/18/2008 United Kingdom
Primary
Secondary
Sleep Disorder Female 12/18/2008 United Kingdom
Primary
Secondary
Sepsis Other Serious 11/12/2008 Male 131 lb 1/12/2009 United States
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 11/1/2007 54 Male 1/20/2009 Physician Japan
Primary
Secondary
Multiple Myeloma Death 1/8/2009 65 Male 187 lb 1/21/2009 United States
Primary
Secondary
Neutrophil Count Decreased Other Serious 75 Male 1/30/2009 Pharmacist United Kingdom
Primary
Secondary
Thrombotic Microangiopathy Other Serious 11/17/2007 54 Male 2/2/2009 Physician Japan
Primary
Secondary
Concomitant
Liver Abscess Other Serious 1/16/2009 Male 75 lb 2/6/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Liver Abscess Other Serious 1/16/2009 Male 75 lb 2/17/2009 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/29/2008 63 Male 2/19/2009 Physician Switzerland
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 57 Female 2/23/2009 Other Health Professional Greece
Primary
Concomitant
Osteonecrosis Other Serious 63 Female 2/23/2009 Other Health Professional Greece
Primary
Concomitant
Osteonecrosis Other Serious 63 Female 2/23/2009 Other Health Professional Greece
Primary
Concomitant
Purulent Discharge Other Serious 75 Female 2/23/2009 Other Health Professional Greece
Primary
Concomitant
Purulent Discharge Other Serious 64 Male 2/23/2009 Other Health Professional Greece
Primary
Concomitant
Purulent Discharge Other Serious 68 Male 2/23/2009 Other Health Professional Greece
Primary
Concomitant
Osteonecrosis Other Serious 79 Male 2/23/2009 Other Health Professional Greece
Primary
Concomitant
Purulent Discharge Other Serious 66 Female 2/23/2009 Other Health Professional Greece
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 1/1/2008 Male 2/24/2009 Physician United States
Primary
Concomitant
Neutrophil Count Decreased 75 Male 2/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Dyspnoea Death 2/23/2009 Male 115 lb 3/2/2009 United States
Primary
Secondary
Concomitant
Tremor Hospitalization Female 2/26/2009 United Kingdom
Primary
Secondary
Nervous System Disorder Death 54 Male 3/9/2009 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 2/8/2009 56 Male 254 lb 3/13/2009 Physician United States
Primary
Concomitant
Dyspnoea Hospitalization 2/23/2009 Male 115 lb 3/16/2009 United States
Primary
Secondary
Concomitant
Pseudomonal Sepsis Other Serious 1/24/2009 Male 4/7/2009 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious Male 4/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Blood Human Chorionic Gonadotropin Increased Other Serious 4/16/2009 Female 4/27/2009 Canada
Primary
Concomitant
Drug Toxicity Other Serious 4/28/2009 United States
Primary
Secondary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Other Serious 1/1/2008 60 Female 5/13/2009 Other Health Professional Japan
Primary
Secondary
Neuropathy Peripheral Hospitalization 1/15/2009 52 Male 5/29/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased 3/30/2009 53 Male 5/29/2009 United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 6/10/2009 Italy
Primary
Secondary
Thrombocytopenia Hospitalization 5/7/2009 Male 219 lb 6/10/2009 United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 6/12/2009 Physician United Kingdom
Primary
Secondary
White Blood Cell Count Decreased Other Serious 6/18/2009 Other Health Professional China
Primary
Secondary
Neuropathy Peripheral Hospitalization 1/15/2009 52 Male 6/12/2009 United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 1/1/2008 43 Male 6/29/2009 Physician United Kingdom
Primary
Secondary
Testicular Pain Other Serious 65 Male 7/17/2009 Other Health Professional United States
Primary
Secondary
Tracheal Obstruction Hospitalization 6/18/2009 Male 7/17/2009 Italy
Primary
Concomitant
Hyperventilation Hospitalization 7/13/2009 Male 159 lb 7/23/2009 Netherlands
Primary
Secondary
Concomitant
Ulcer Other Serious 2/1/1997 Male 7/28/2009 Physician United States
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 6/18/2009 Male 8/10/2009 Italy
Primary
Concomitant
Thrombocytopenia Death 8/10/2009 Male 8/10/2009 Pharmacist United States
Primary
Concomitant
Hallucination Other Serious 8/6/2009 Male 137 lb 8/19/2009 United States
Primary
Secondary
Concomitant
Soft Tissue Infection Life Threatening 7/6/2009 Male 183 lb 8/25/2009 United States
Primary
Secondary
Concomitant
Soft Tissue Infection Life Threatening 7/17/2009 Male 183 lb 8/28/2009 United States
Primary
Secondary
Concomitant
Leukopenia Hospitalization 8/12/2009 54 Female 110 lb 8/28/2009 Physician United States
Primary
Secondary
Concomitant
Hepatic Failure Hospitalization 49 Male 9/1/2009 Other Health Professional United States
Primary
Secondary
Febrile Neutropenia Other Serious 8/31/2009 54 Female 110 lb 9/8/2009 Physician United States
Primary
Secondary
Concomitant
Hyperventilation Hospitalization 7/13/2009 Male 159 lb 9/8/2009 Netherlands
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 8/31/2009 54 Female 110 lb 9/11/2009 Physician United States
Primary
Secondary
Concomitant
Ileus Hospitalization 8/19/2009 Male 182 lb 9/16/2009 United States
Primary
Secondary
Concomitant
Cardiac Failure Death 8/18/2009 9/18/2009 Physician Germany
Primary
Concomitant
Infection Death 9/22/2009 Physician Italy
Primary
Secondary
Concomitant
Cardiac Failure Death 8/18/2009 10/16/2009 Physician Germany
Primary
Concomitant
Rash Other Serious 41 Female 10/23/2009 Other Health Professional Italy
Primary
Concomitant
Respiratory Failure Hospitalization Male 11/2/2009 Poland
Primary
Concomitant
Respiratory Failure Other Serious Male 11/6/2009 Poland
Primary
Concomitant
Hallucination Other Serious 8/6/2009 86 Male 137 lb 11/6/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Other Serious 5/15/2009 Female 11/18/2009 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 11/1/2009 Male 218 lb 11/23/2009 Physician United States
Primary
Secondary
Concomitant
Intervertebral Disc Protrusion Other Serious 12/16/2009 Other Health Professional Germany
Primary
Secondary
Staphylococcal Infection Life Threatening 10/19/2009 Female 59 lb 12/9/2009 Physician United States
Primary
Concomitant
Multiple Myeloma Death 10/21/2009 Male 12/31/2009 Physician United States
Primary
Concomitant
Vomiting Other Serious 1/11/2010 Korea, Republic Of
Primary
Secondary
Concomitant
Photopsia Other Serious 9/27/2009 Female 1/12/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/20/2010 Other Health Professional China
Primary
Secondary
Orthostatic Hypotension Hospitalization 2/11/2008 59 Female 176 lb 1/25/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 67 Female 1/28/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Leukopenia Hospitalization 8/12/2009 54 Female 110 lb 2/5/2010 Physician United States
Primary
Secondary
Concomitant
Stomatitis Necrotising Life Threatening 12/23/2009 Male 2/8/2010 Physician Italy
Primary
Secondary
Multiple Myeloma Death 10/21/2009 Male 2/12/2010 Physician United States
Primary
Concomitant
Multiple Myeloma Death 68 Male 2/12/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Pneumonia Death 2/18/2010 Physician Italy
Primary
Secondary
Concomitant
Blood Creatinine Increased Other Serious 2/18/2010 Physician Italy
Primary
Secondary
Concomitant
Septic Shock Death 2/18/2010 Physician Italy
Primary
Secondary
Concomitant
Septic Shock Death 2/19/2010 Physician Italy
Primary
Secondary
Concomitant
Diverticulitis Death 2/19/2010 Physician Italy
Primary
Secondary
Concomitant
Cardiac Disorder Other Serious 2/22/2010 Korea, Republic Of
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 67 Female 2/25/2010 Other Health Professional Italy
Primary
Secondary
Vomiting Other Serious 7/1/1999 Male 3/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Hospitalization 2/2/2010 69 Male 179 lb 3/2/2010 United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 9/1/2009 Female 3/4/2010 Greece
Primary
Secondary
Concomitant
Pneumonia Death 3/8/2010 Consumer United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 57 Female 3/8/2010 Other Health Professional Poland
Primary
Secondary
Concomitant
Vomiting Other Serious 7/1/1999 Male 3/10/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 3/11/2010 Other Health Professional Greece
Primary
Secondary
Multiple Myeloma Death 10/21/2009 Male 3/11/2010 Physician United States
Primary
Concomitant
Salmonellosis Life Threatening 65 Male 3/19/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Jaundice Other Serious 3/25/2009 Female 143 lb 3/22/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 7/1/1999 Male 3/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2003 Female 3/23/2010 Other Health Professional United States
Primary
Concomitant
Visual Impairment Other Serious 57 Female 3/26/2010 Other Health Professional Poland
Primary
Secondary
Concomitant
Blood Creatinine Increased Other Serious 73 Female 3/26/2010 Physician Italy
Primary
Secondary
Concomitant
Diverticulitis Death 12/15/2006 67 Male 3/26/2010 Physician Italy
Primary
Secondary
Concomitant
Septic Shock Life Threatening 3/16/2007 57 Male 3/26/2010 Physician Italy
Primary
Secondary
Concomitant
Septic Shock Death 6/26/2007 76 Male 3/26/2010 Physician Italy
Primary
Secondary
Concomitant
Disease Progression Other Serious 9/1/2009 Female 3/29/2010 Greece
Primary
Secondary
Concomitant
Hepatitis B Other Serious 1/22/2007 70 Female 3/30/2010 Physician Italy
Primary
Secondary
Tremor Hospitalization 3/14/2010 67 Male 203 lb 4/1/2010 Physician United States
Primary
Secondary
Concomitant
Sepsis Other Serious 1/1/2009 50 Male 4/6/2010 Physician United States
Primary
Secondary
Concomitant
Hypercalcaemia Other Serious 4/7/2010 Other Health Professional United States
Primary
Secondary
Encephalitis Other Serious 4/7/2010 Other Health Professional United States
Primary
Secondary
Erectile Dysfunction Other Serious Male 4/7/2010 Other Health Professional United States
Primary
Secondary
Pulmonary Embolism Other Serious 4/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Shock Other Serious 65 Male 4/7/2010
Primary
Secondary
Concomitant
Vomiting Other Serious 4/8/2010 Korea, Republic Of
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/8/2009 71 Male 181 lb 4/8/2010 Other Health Professional Germany
Primary
Secondary
Oedema Peripheral Other Serious 3/6/2010 49 Male 184 lb 4/8/2010 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 4/9/2010 Italy
Primary
Secondary
Hypophosphataemia Other Serious 3/11/2010 61 Male 4/15/2010 Physician United States
Primary
Secondary
Pyrexia Other Serious 4/16/2010 Physician Finland
Primary
Concomitant
Vomiting Other Serious 1/1/2000 56 Male 4/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 3/29/2010 62 Male 208 lb 4/21/2010 United States
Primary
Secondary
Concomitant
Haematotoxicity Death 1/1/2009 66 Female 4/23/2010 Spain
Primary
Concomitant
Interstitial Lung Disease Other Serious 67 Male 4/27/2010 Korea, Republic Of
Primary
Secondary
Concomitant
Sepsis Other Serious 1/1/2009 50 Male 4/29/2010 Physician United States
Primary
Secondary
Concomitant
Haematotoxicity Death 1/1/2009 66 Male 4/30/2010 Spain
Primary
Concomitant
Haematotoxicity Death 1/1/2009 66 Male 5/3/2010 Spain
Primary
Concomitant
Pyrexia Other Serious 1/1/2010 63 Female 5/7/2010 Physician Finland
Primary
Concomitant
Pneumonia Hospitalization 4/10/2010 62 Male 141 lb 5/7/2010 Physician United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Disability 12/1/2009 55 Male 192 lb 5/4/2010 Other Health Professional United Kingdom
Primary
Secondary
Lymphopenia Other Serious 5/7/2010 54 Male 147 lb 5/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Jaundice Other Serious 3/25/2009 41 Female 143 lb 5/12/2010 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 5/7/2010 54 Male 147 lb 5/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pancytopenia Death 5/14/2010 Physician France
Primary
Concomitant
Circulatory Collapse Death 5/14/2010 Physician France
Primary
Concomitant
Bronchopneumonia Death 5/14/2010 Physician France
Primary
Concomitant
Pulmonary Embolism Death 4/25/2010 62 Female 194 lb 5/14/2010 Pharmacist United States
Primary
Secondary
Concomitant
Arthralgia Other Serious 5/25/2010 Physician United States
Primary
Secondary
Syncope Other Serious 5/26/2010 Physician United States
Primary
Secondary

Drug Data