Bortezomib combined with Thalidomide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Toothache Other Serious 3/1/2005 62 Male 2/24/2006 United States
Primary
Concomitant
Pneumonia Life Threatening 12/30/2005 62 Female 160 lb 6/22/2006 Physician United States
Primary
Concomitant
Pain Other Serious 11/1/2005 48 Male 4/13/2007 Spain
Primary
Secondary
Pain Other Serious 11/1/2005 48 Male 4/21/2007 Spain
Primary
Secondary
Renal Failure Acute Life Threatening 10/5/2007 64 Male 2/29/2008 France
Primary
Secondary
Concomitant
Hyperglycaemia Hospitalization 1/14/2008 Male 5/28/2008 Physician United States
Primary
Secondary
Tumour Lysis Syndrome Other Serious 1/1/2007 62 Female 8/13/2008 Other Health Professional China
Primary
Secondary
Tachypnoea Death 9/2/2008 Male 258 lb 9/9/2008 Pharmacist United States
Primary
Secondary
Tumour Lysis Syndrome Other Serious 1/1/2006 62 Female 9/26/2008
Primary
Secondary
Concomitant
Hyperglycaemia Hospitalization 1/14/2008 Male 338 lb 10/13/2008 Physician United States
Primary
Secondary
Tumour Lysis Syndrome Hospitalization 62 Female 12/2/2008 Other Health Professional China
Primary
Concomitant
Osteonecrosis Other Serious 57 Female 2/23/2009 Other Health Professional Greece
Primary
Concomitant
Osteonecrosis Other Serious 63 Female 2/23/2009 Other Health Professional Greece
Primary
Concomitant
Osteonecrosis Other Serious 63 Female 2/23/2009 Other Health Professional Greece
Primary
Concomitant
Purulent Discharge Other Serious 75 Female 2/23/2009 Other Health Professional Greece
Primary
Concomitant
Osteonecrosis Other Serious 48 Female 2/23/2009 Other Health Professional Greece
Primary
Concomitant
Purulent Discharge Other Serious 64 Male 2/23/2009 Other Health Professional Greece
Primary
Concomitant
Purulent Discharge Other Serious 68 Male 2/23/2009 Other Health Professional Greece
Primary
Concomitant
Osteonecrosis Other Serious 79 Male 2/23/2009 Other Health Professional Greece
Primary
Concomitant
Purulent Discharge Other Serious 66 Female 2/23/2009 Other Health Professional Greece
Primary
Concomitant
Osteonecrosis Other Serious 54 Female 2/24/2009 Other Health Professional Greece
Primary
Concomitant
Osteonecrosis Other Serious 30 Male 2/24/2009 Other Health Professional Greece
Primary
Concomitant
Purulent Discharge Other Serious 52 Male 2/24/2009 Other Health Professional Greece
Primary
Concomitant
Purulent Discharge Other Serious 70 Female 2/24/2009 Other Health Professional Greece
Primary
Concomitant
Purulent Discharge Other Serious 64 Male 2/24/2009 Other Health Professional Greece
Primary
Concomitant
Purulent Discharge Other Serious 76 Female 2/24/2009 Other Health Professional Greece
Primary
Concomitant
Osteonecrosis Other Serious 75 Male 2/24/2009 Other Health Professional Greece
Primary
Concomitant
Nervous System Disorder Death 54 Male 3/9/2009 Consumer United States
Primary
Secondary
Concomitant
Stem Cell Transplant Death 54 Male 3/9/2009 United States
Primary
Concomitant
Febrile Neutropenia Other Serious 4/14/2009 Consumer United Kingdom
Primary
Secondary
Febrile Neutropenia Other Serious 4/27/2009 Consumer United Kingdom
Primary
Secondary
Thrombocytopenia Other Serious 4/28/2009 Spain
Primary
Secondary
Drug Rash With Eosinophilia And Systemic Symptoms Other Serious 1/1/2008 60 Female 5/13/2009 Other Health Professional Japan
Primary
Secondary
Toxic Skin Eruption Hospitalization 4/24/2009 Female 5/19/2009 Switzerland
Primary
Secondary
Neutropenia Other Serious 6/10/2009 Italy
Primary
Secondary
Renal Impairment Other Serious 1/1/2009 Female 7/22/2009 Italy
Primary
Concomitant
Renal Impairment Other Serious 1/1/2009 Female 8/17/2009 Italy
Primary
Concomitant
Renal Impairment Other Serious 1/1/2009 Female 9/1/2009 Italy
Primary
Concomitant
Infection Death 9/22/2009 Physician Italy
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization Male 11/2/2009 Poland
Primary
Concomitant
Respiratory Failure Other Serious Male 11/6/2009 Poland
Primary
Concomitant
Wound Infection Staphylococcal Hospitalization 1/26/2009 51 Female 11/24/2009 Other Health Professional France
Primary
Secondary
Concomitant
Pancytopenia Other Serious 39 Female 12/3/2009 Physician United States
Primary
Secondary
Septic Shock Other Serious 12/10/2009 Israel
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2005 39 Male 2/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 65 Female 2/12/2010 Other Health Professional Belgium
Primary
Secondary
Concomitant
Multiple Myeloma Death 68 Male 2/12/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Cardiac Disorder Other Serious 2/22/2010 Korea, Republic Of
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 67 Female 2/25/2010 Other Health Professional Italy
Primary
Secondary
Pneumonia Death 3/8/2010 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 3/11/2010 Other Health Professional Greece
Primary
Secondary
Stem Cell Transplant Hospitalization 65 Male 3/18/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2003 Female 3/23/2010 Other Health Professional United States
Primary
Concomitant
Hypercalcaemia Other Serious 4/7/2010 Other Health Professional United States
Primary
Secondary
Encephalitis Other Serious 4/7/2010 Other Health Professional United States
Primary
Secondary
Erectile Dysfunction Other Serious Male 4/7/2010 Other Health Professional United States
Primary
Secondary
Pulmonary Embolism Other Serious 4/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Shock Other Serious 65 Male 4/7/2010
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 4/9/2010 Italy
Primary
Secondary
Hypophosphataemia Other Serious 3/11/2010 61 Male 4/15/2010 Physician United States
Primary
Secondary
Interstitial Lung Disease Other Serious 67 Male 4/27/2010 Korea, Republic Of
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 64 Female 7/7/2010 Physician Ireland
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/9/2010 Other Health Professional Spain
Primary
Secondary
Thrombocytopenia Other Serious 7/21/2010 China
Primary
Secondary
Pathogen Resistance Hospitalization 69 Male 8/10/2010 Physician United States
Primary
Concomitant
Myocardial Ischaemia Hospitalization 3/21/2008 79 Female 8/10/2010 Physician Japan
Primary
Secondary
Red Blood Cell Count Decreased Other Serious 8/23/2010 Japan
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 9/2/2010 Physician United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 9/2/2010 Physician United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 9/2/2010 Physician United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 9/2/2010 Physician United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 9/2/2010 Physician United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 9/2/2010 Physician United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 9/2/2010 Physician United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 9/2/2010 Physician United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 9/2/2010 Physician United States
Primary
Secondary
Concomitant
Herpes Zoster Other Serious 9/2/2010 Physician United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 9/2/2010 Physician United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 9/2/2010 Physician United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 9/2/2010 Physician United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 9/2/2010 Physician United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 9/2/2010 Physician United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 9/2/2010 Physician United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 9/2/2010 Physician United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 9/2/2010 Physician United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 9/2/2010 Physician United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 9/2/2010 Physician United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 9/2/2010 Physician United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 9/2/2010 Physician United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 9/2/2010 Physician United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 9/2/2010 Physician United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 9/2/2010 Physician United States
Primary
Secondary
Concomitant
Herpes Zoster Other Serious 9/2/2010 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/6/2010 45 Female 8/30/2010 Australia
Primary
Secondary
Thrombocytopenia Other Serious 9/7/2010 Other Health Professional Spain
Primary
Secondary
Myocardial Ischaemia Other Serious 79 Female 9/8/2010
Primary
Secondary
Neuralgia Other Serious 61 Female 9/8/2010
Primary
Secondary
Graft Versus Host Disease Other Serious 9/17/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Vasculitis Other Serious 9/21/2010 Physician Italy
Primary
Concomitant
Vasculitis Other Serious 9/22/2010 Italy
Primary
Concomitant
Vasculitis Other Serious 9/22/2010 Physician Italy
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2003 60 Female 9/29/2010 Other Health Professional United States
Primary
Concomitant
Platelet Count Decreased Hospitalization 7/6/2010 45 Female 9/27/2010 Australia
Primary
Secondary
Multiple Myeloma Other Serious 11/3/2010 Other Health Professional United States
Primary
Concomitant
Multiple Myeloma Hospitalization 7/6/2010 45 Female 10/26/2010 Australia
Primary
Secondary
Multiple Myeloma Other Serious Male 11/5/2010 Other Health Professional United States
Primary
Concomitant
Oesophagitis Hospitalization 7/6/2010 45 Female 10/29/2010 Australia
Primary
Secondary
Lung Infection Other Serious 3/1/2007 53 Male 11/11/2010 Consumer Germany
Primary
Concomitant
Vomiting Other Serious 71 10/25/2010 Physician Italy
Primary
Secondary
Neoplasm Other Serious 12/2/2010 Physician Italy
Primary
Secondary
Myocardial Infarction Other Serious 12/2/2010 Physician Italy
Primary
Secondary
Deep Vein Thrombosis Other Serious 10/25/2010 United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Other Serious 10/25/2010 United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 59 Male 12/20/2010 Physician Greece
Primary
Secondary
Hyperuricaemia Other Serious 12/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Confusional State Other Serious 12/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 12/22/2010 Physician United States
Primary
Secondary
Concomitant
Bradycardia Other Serious 12/22/2010 Physician United States
Primary
Secondary
Bacteraemia Other Serious 12/22/2010 Other Health Professional United States
Primary
Secondary
Toxic Epidermal Necrolysis Hospitalization 1/26/2009 51 Female 169 lb 12/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Disease Progression Other Serious 1/7/2011 Italy
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/12/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Other Serious 40 Female 1/18/2011 Other Health Professional Italy
Primary
Secondary
Neuropathy Peripheral Other Serious 59 Male 2/2/2011 Physician Greece
Primary
Secondary
Influenza Like Illness Other Serious 8/18/2003 61 Female 2/7/2011 Other Health Professional United States
Primary
Concomitant
Humerus Fracture Other Serious 45 Female 3/3/2011 Physician United States
Primary
Concomitant
Bradycardia Other Serious 3/11/2011 Physician United States
Primary
Secondary
Interstitial Lung Disease Other Serious 3/11/2011 Physician United States
Primary
Secondary
Concomitant
Hyperuricaemia Other Serious 3/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Confusional State Other Serious 3/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Bacteraemia Other Serious 3/11/2011 Other Health Professional United States
Primary
Secondary
Gastrointestinal Inflammation Other Serious 3/23/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Cytomegaloviral Other Serious 3/23/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Gastrointestinal Inflammation Other Serious 3/23/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Gastrointestinal Inflammation Other Serious 3/23/2011 Physician United States
Primary
Secondary
Concomitant
Gastrointestinal Inflammation Other Serious 3/23/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Gastrointestinal Inflammation Other Serious 3/23/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Gastrointestinal Inflammation Other Serious 3/23/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Gastrointestinal Inflammation Other Serious 3/23/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Gastrointestinal Inflammation Other Serious 3/23/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Gastrointestinal Inflammation Other Serious 3/23/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Gastrointestinal Inflammation Other Serious 3/23/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Gastrointestinal Inflammation Other Serious 3/23/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Gastrointestinal Inflammation Other Serious 3/23/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Gastrointestinal Inflammation Other Serious 3/23/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Gastrointestinal Inflammation Other Serious 3/23/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Gastrointestinal Inflammation Other Serious 3/23/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Gastrointestinal Inflammation Other Serious 3/23/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Gastrointestinal Inflammation Other Serious 3/23/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Gastrointestinal Inflammation Other Serious 3/23/2011 Physician United States
Primary
Secondary
Concomitant

Drug Data