Bortezomib combined with Doxorubicin Hcl

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pyrexia Hospitalization 10/30/2006 63 Male 229 lb 11/3/2006 Other Health Professional United States
Primary
Secondary
Paraesthesia Hospitalization 54 Male 11/7/2006 Other Health Professional United Kingdom
Primary
Secondary
Pain In Jaw Hospitalization 6/30/2007 57 Male 230 lb 7/11/2007 Other Health Professional United States
Primary
Secondary
Rhabdomyolysis Life Threatening 10/23/2007 Female 159 lb 10/31/2007 Pharmacist United States
Primary
Secondary
Stevens-johnson Syndrome Hospitalization 10/20/2007 Female 128 lb 11/7/2007 Physician Italy
Primary
Secondary
Stevens-johnson Syndrome Hospitalization 10/20/2007 Female 128 lb 11/20/2007 Physician Italy
Primary
Secondary
Sinusitis Hospitalization 11/29/2007 61 Male 204 lb 12/5/2007 Other Health Professional United States
Primary
Secondary
Pulmonary Embolism Other Serious 12/26/2007 54 Male 192 lb 12/27/2007 Other Health Professional United States
Primary
Secondary
Embolism Other Serious 2/1/2008 48 Male 282 lb 2/7/2008 Other Health Professional United States
Primary
Secondary
Respiratory Failure Life Threatening 1/29/2008 78 Male 172 lb 3/13/2008 Physician Italy
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 1/29/2008 78 Male 172 lb 4/4/2008 Physician Italy
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 1/29/2008 78 Male 172 lb 4/4/2008 Physician Italy
Primary
Secondary
Concomitant
Haemorrhage Other Serious 4/7/2008 Other Health Professional Italy
Primary
Secondary
Pyrexia Other Serious 5/19/2008 74 Male 167 lb 5/19/2008 Other Health Professional United States
Primary
Secondary
Hyperglycaemia Hospitalization 1/14/2008 Male 5/28/2008 Physician United States
Primary
Secondary
Renal Injury Other Serious 5/28/2008 74 Male 156 lb 5/30/2008 Other Health Professional United States
Primary
Secondary
Renal Failure Life Threatening 2/1/2008 Female 150 lb 6/9/2008 Physician Germany
Primary
Secondary
Concomitant
Cardiac Failure Acute Death 6/10/2008 Physician Italy
Primary
Secondary
Dizziness Hospitalization 6/23/2008 68 Male 225 lb 6/23/2008 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 6/26/2008 59 Male 198 lb 7/1/2008 Other Health Professional United States
Primary
Secondary
Cardiac Failure Acute Death 8/22/2006 79 Female 7/25/2008 Physician Italy
Primary
Secondary
Concomitant
Thrombocytopenia Male 8/4/2008 United Kingdom
Primary
Secondary
White Blood Cell Count Decreased Other Serious 7/14/2008 Male 192 lb 8/8/2008 Other Health Professional United States
Primary
Secondary
Nausea Hospitalization 1/31/2006 Male 154 lb 10/23/2008 United States
Primary
Secondary
Concomitant
Sepsis Other Serious 11/12/2008 Male 131 lb 1/12/2009 United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 2/8/2009 56 Male 254 lb 3/13/2009 Physician United States
Primary
Concomitant
Renal Failure Other Serious 5/1/2009 Physician United States
Primary
Secondary
Concomitant
Neutropenia Other Serious 6/10/2009 Italy
Primary
Secondary
Thrombocytopenia Other Serious 6/12/2009 Physician United Kingdom
Primary
Secondary
Staphylococcal Infection Other Serious 1/1/2008 43 Male 6/29/2009 Physician United Kingdom
Primary
Secondary
Pyrexia Hospitalization 59 Male 7/2/2009 Physician Israel
Primary
Secondary
Pyrexia Hospitalization 59 Male 8/3/2009 Physician Israel
Primary
Secondary
Stenotrophomonas Infection Life Threatening 7/28/2009 Female 21 lb 9/1/2009 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 12/1/2009 Consumer United Kingdom
Primary
Secondary
Pancytopenia Other Serious 39 Female 12/3/2009 Physician United States
Primary
Secondary
Full Blood Count Decreased Hospitalization 12/2/2009 80 Female 162 lb 12/4/2009 Other Health Professional United States
Primary
Secondary
Vomiting Hospitalization 11/22/2009 Male 168 lb 12/11/2009 Physician United States
Primary
Secondary
Concomitant
Neurotoxicity Other Serious 12/15/2009 Physician France
Primary
Secondary
Neurotoxicity Other Serious 12/15/2009 Physician France
Primary
Secondary
Neurotoxicity Other Serious 12/15/2009 Physician France
Primary
Secondary
Neurotoxicity Other Serious 12/15/2009 Physician France
Primary
Secondary
Neurotoxicity Other Serious 12/15/2009 Physician France
Primary
Secondary
Neurotoxicity Other Serious 12/15/2009 Physician France
Primary
Secondary
Neurotoxicity Other Serious 12/15/2009 Physician France
Primary
Secondary
Neurotoxicity Other Serious 12/15/2009 Physician France
Primary
Secondary
Neurotoxicity Other Serious 12/15/2009 Physician France
Primary
Secondary
Neurotoxicity Other Serious 12/15/2009 Physician France
Primary
Secondary
Staphylococcal Infection Life Threatening 10/19/2009 Female 59 lb 12/9/2009 Physician United States
Primary
Concomitant
Dehydration Hospitalization 12/3/2009 80 Female 162 lb 12/31/2009 Other Health Professional United States
Primary
Secondary
Left Ventricular Dysfunction Other Serious 11/22/2009 Male 168 lb 1/11/2010 Physician United States
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 67 Female 1/28/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 10/1/2009 Male 160 lb 1/29/2010 Physician United States
Primary
Secondary
Concomitant
Stomatitis Necrotising Life Threatening 12/23/2009 Male 2/8/2010 Physician Italy
Primary
Secondary
Tooth Extraction Other Serious 10/1/2009 Male 160 lb 2/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Death 2/18/2010 Physician Italy
Primary
Secondary
Concomitant
Blood Creatinine Increased Other Serious 2/18/2010 Physician Italy
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 10/20/2007 Female 128 lb 2/18/2010 Physician Italy
Primary
Secondary
Septic Shock Death 2/18/2010 Physician Italy
Primary
Secondary
Concomitant
Septic Shock Death 2/19/2010 Physician Italy
Primary
Secondary
Concomitant
Diverticulitis Death 2/19/2010 Physician Italy
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 67 Female 2/25/2010 Other Health Professional Italy
Primary
Secondary
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 67 Female 3/1/2010 Italy
Primary
Secondary
Concomitant
Thrombocytopenia Death 3/11/2010 Italy
Primary
Secondary
Thrombocytopenia Death Unknown 3/11/2010 Physician Italy
Primary
Secondary
Thrombocytopenia Death 3/11/2010 Italy
Primary
Secondary
Visual Impairment Other Serious 57 Female 3/26/2010 Other Health Professional Poland
Primary
Secondary
Concomitant
Blood Creatinine Increased Other Serious 73 Female 3/26/2010 Physician Italy
Primary
Secondary
Concomitant
Diverticulitis Death 12/15/2006 67 Male 3/26/2010 Physician Italy
Primary
Secondary
Concomitant
Septic Shock Life Threatening 3/16/2007 57 Male 3/26/2010 Physician Italy
Primary
Secondary
Concomitant
Septic Shock Death 6/26/2007 76 Male 3/26/2010 Physician Italy
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 4/18/2010 65 Female 166 lb 4/27/2010 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Death 4/25/2010 62 Female 194 lb 5/14/2010 Pharmacist United States
Primary
Secondary
Concomitant
Arthralgia Other Serious 5/25/2010 Physician United States
Primary
Secondary
Syncope Other Serious 5/26/2010 Physician United States
Primary
Secondary
Confusional State Other Serious 5/26/2010 Physician United States
Primary
Secondary
Insomnia Other Serious 5/26/2010 Physician United States
Primary
Secondary
Arthralgia Other Serious 5/26/2010 Physician United States
Primary
Secondary
Cellulitis Hospitalization 4/28/2008 Male 5/26/2010 Physician United States
Primary
Secondary
Renal Failure Other Serious 51 Male 6/18/2010 Other Health Professional Austria
Primary
Secondary
Concomitant
Infection Death 6/21/2010 Physician United States
Primary
Secondary
Pneumonia Death 11/4/2007 46 Male 6/23/2010 Physician Italy
Primary
Secondary
Concomitant
Diverticulitis Death 12/15/2006 63 Male 6/23/2010 Physician Italy
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 4/18/2010 65 Female 166 lb 6/28/2010 Physician United States
Primary
Secondary
Concomitant
Stem Cell Transplant Other Serious 51 Male 6/24/2010 Other Health Professional Austria
Primary
Secondary
Concomitant
Diverticulitis Death 12/15/2006 63 Male 7/16/2010 Physician Italy
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/17/2010 Austria
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 7/20/2010 Other Health Professional United States
Primary
Secondary
Renal Failure Acute Other Serious 1/1/2009 55 Male 186 lb 8/6/2010 Physician United States
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Other Serious 8/23/2010 Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/19/2009 62 Male 207 lb 8/31/2010 Other Health Professional France
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 9/1/2010 Physician United Kingdom
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 7/6/2010 45 Female 8/30/2010 Australia
Primary
Secondary
Neuralgia Other Serious 61 Female 9/8/2010
Primary
Secondary
Peripheral Sensory Neuropathy Other Serious 9/16/2010 Consumer United Kingdom
Primary
Secondary
Toxic Encephalopathy Hospitalization 66 Male 9/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious 1/1/2010 58 Male 9/27/2010 Other Health Professional Netherlands
Primary
Secondary
Silent Myocardial Infarction Other Serious 1/1/2010 62 Male 9/27/2010 Other Health Professional Netherlands
Primary
Secondary
Transient Ischaemic Attack Other Serious 1/1/2010 63 Male 9/27/2010 Other Health Professional Netherlands
Primary
Secondary
Transient Ischaemic Attack Other Serious 63 Male 9/24/2010 Netherlands
Primary
Secondary
Thrombocytopenia Other Serious 10/14/2010 Physician United States
Primary
Secondary
Wound Infection Other Serious 10/26/2010 Physician United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 10/27/2010 Other Health Professional United States
Primary
Secondary
Multiple Myeloma Hospitalization 7/6/2010 45 Female 10/26/2010 Australia
Primary
Secondary
Syncope Hospitalization 9/28/2010 75 Male 11/3/2010 Pharmacist United States
Primary
Secondary
Oesophagitis Hospitalization 7/6/2010 45 Female 10/29/2010 Australia
Primary
Secondary
Death Death 11/18/2010 Other Health Professional United States
Primary
Secondary
Infection Death 11/18/2010 Other Health Professional United States
Primary
Secondary
Myocardial Infarction Death 11/30/2010 Other Health Professional Korea, Republic Of
Primary
Secondary
Infection Death 11/30/2010 Physician Greece
Primary
Secondary
Concomitant
Left Ventricular Dysfunction Other Serious 11/22/2009 61 Male 168 lb 12/8/2010 Physician United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 59 Male 12/20/2010 Physician Greece
Primary
Secondary
Muscular Weakness Other Serious 12/21/2010 Physician United States
Primary
Secondary
Concomitant
Mood Altered Other Serious 12/21/2010 Physician United States
Primary
Secondary
Concomitant
Mood Altered Other Serious 12/21/2010 Physician United States
Primary
Secondary
Concomitant
Lymphopenia Other Serious 12/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hypoalbuminaemia Other Serious 12/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hyperuricaemia Other Serious 12/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Confusional State Other Serious 12/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Ileus Paralytic Death 12/21/2010 Physician Greece
Primary
Secondary
Interstitial Lung Disease Other Serious 12/22/2010 Physician United States
Primary
Secondary
Concomitant
Bradycardia Other Serious 12/22/2010 Physician United States
Primary
Secondary
Bacteraemia Other Serious 12/22/2010 Other Health Professional United States
Primary
Secondary
Death Death 1/1/2010 42 Male 1/12/2011 Physician Switzerland
Primary
Concomitant
Neuropathy Peripheral Other Serious 59 Male 2/2/2011 Physician Greece
Primary
Secondary
Klebsiella Sepsis Death 3/1/2011 Physician United States
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 3/3/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 3/9/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 3/11/2011 Physician United States
Primary
Secondary
Concomitant
Muscular Weakness Other Serious 3/11/2011 Physician United States
Primary
Secondary
Concomitant
Mood Altered Other Serious 3/11/2011 Physician United States
Primary
Secondary
Concomitant
Mood Altered Other Serious 3/11/2011 Physician United States
Primary
Secondary
Concomitant
Cardiomyopathy Other Serious 3/21/2011 Physician United Kingdom
Primary
Secondary
Infection Death 4/19/2011 Physician United States
Primary
Secondary
Interstitial Lung Disease Other Serious 5/9/2011 Physician United States
Primary
Secondary
Concomitant
Sepsis Death Female 5/10/2011 Physician Hungary
Primary
Secondary
Gastrointestinal Haemorrhage Hospitalization 2/8/2008 53 Male 154 lb 5/11/2011 Physician United States
Primary
Secondary
Myelodysplastic Syndrome Other Serious 3/28/2007 55 Female 5/11/2011 Other Health Professional United States
Primary
Secondary
Acute Graft Versus Host Disease In Intestine Other Serious 66 Male 5/12/2011 Physician United States
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease In Intestine Other Serious 64 Female 5/13/2011 Physician United States
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease In Intestine Other Serious 66 Male 5/13/2011 Physician United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 5/23/2011 Physician United States
Primary
Secondary
Concomitant
Bradycardia Other Serious 5/23/2011 Physician United States
Primary
Secondary
Disease Progression Other Serious 5/26/2011 United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 7/30/2010 45 Female 5/20/2011 Australia
Primary
Secondary
Pulmonary Embolism Death 6/3/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 7/6/2010 45 Female 5/24/2011 Australia
Primary
Secondary
Chest Pain Hospitalization 7/30/2010 45 Female 5/24/2011 Australia
Primary
Secondary
Neutropenia Hospitalization 4/10/2010 57 Female 112 lb 4/13/2011 United States
Primary
Secondary
Herpes Zoster Other Serious 6/29/2011 Other Health Professional China
Primary
Concomitant
Interstitial Lung Disease Other Serious 7/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data