Bortezomib combined with Revlimid

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Failure Life Threatening 2/1/2008 Female 150 lb 6/9/2008 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/1/2008 Male 157 lb 10/8/2008 United States
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 2/1/2008 Male 190 lb 10/13/2008 United States
Primary
Secondary
Pancytopenia Life Threatening 10/16/2008 87 Male 10/22/2008 United States
Primary
Secondary
Concomitant
Herpes Virus Infection Other Serious 9/29/2008 Male 11/11/2008 Physician United States
Primary
Secondary
Concomitant
Febrile Neutropenia Life Threatening 10/16/2008 87 Male 1/9/2009 United States
Primary
Secondary
Concomitant
Febrile Neutropenia Life Threatening 10/16/2008 87 Male 1/9/2009 United States
Primary
Secondary
Concomitant
Sepsis Other Serious 11/12/2008 Male 131 lb 1/12/2009 United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 10/16/2008 87 Male 1/15/2009 United States
Primary
Secondary
Concomitant
Multiple Myeloma Death 1/8/2009 65 Male 187 lb 1/21/2009 United States
Primary
Secondary
Pulmonary Embolism Hospitalization 11/29/2008 63 Male 2/19/2009 Physician Switzerland
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 1/1/2008 Male 2/24/2009 Physician United States
Primary
Concomitant
Dyspnoea Death 2/23/2009 Male 115 lb 3/2/2009 United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 2/23/2009 Male 115 lb 3/16/2009 United States
Primary
Secondary
Concomitant
Right Ventricular Dysfunction Other Serious 7/1/2008 77 Male 3/19/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Pseudomonal Sepsis Other Serious 1/24/2009 Male 4/7/2009 Physician United States
Primary
Concomitant
Lower Gastrointestinal Haemorrhage Hospitalization 4/4/2009 Male 185 lb 4/21/2009 United States
Primary
Secondary
Concomitant
Pseudomonal Sepsis Other Serious 1/21/2009 Male 5/4/2009 Physician United States
Primary
Concomitant
Sepsis Hospitalization 1/7/2009 Male 187 lb 5/14/2009 Germany
Primary
Concomitant
Respiratory Failure Hospitalization 4/28/2009 Female 168 lb 5/18/2009 United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 1/1/2008 Male 5/27/2009 Physician United States
Primary
Concomitant
Therapeutic Response Unexpected Other Serious 2/28/2009 Male 6/3/2009 Other Health Professional Spain
Primary
Concomitant
Neutropenia Other Serious 6/10/2009 Italy
Primary
Secondary
Thrombocytopenia Hospitalization 5/7/2009 Male 219 lb 6/10/2009 United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 4/1/2009 Female 6/16/2009 Physician United States
Primary
Secondary
Concomitant
Multiple Myeloma Death 1/1/2009 Female 6/29/2009 Spain
Primary
Concomitant
Tracheal Obstruction Hospitalization 6/18/2009 Male 7/17/2009 Italy
Primary
Concomitant
Hyperventilation Hospitalization 7/13/2009 Male 159 lb 7/23/2009 Netherlands
Primary
Secondary
Concomitant
Feeling Abnormal Death 3/1/2009 Male 7/27/2009 Consumer Netherlands
Primary
Concomitant
Sepsis Hospitalization 1/7/2009 Male 187 lb 7/31/2009 Germany
Primary
Secondary
Concomitant
Pneumonia Other Serious 3/1/2009 Male 8/7/2009 Other Health Professional Netherlands
Primary
Concomitant
Pancytopenia Hospitalization 6/18/2009 Male 8/10/2009 Italy
Primary
Concomitant
Thrombocytopenia Death 8/10/2009 Male 8/10/2009 Pharmacist United States
Primary
Concomitant
Hallucination Other Serious 8/6/2009 Male 137 lb 8/19/2009 United States
Primary
Secondary
Concomitant
Soft Tissue Infection Life Threatening 7/6/2009 Male 183 lb 8/25/2009 United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 6/22/2009 Male 210 lb 8/26/2009 United States
Primary
Secondary
Concomitant
Soft Tissue Infection Life Threatening 7/17/2009 Male 183 lb 8/28/2009 United States
Primary
Secondary
Concomitant
Hyperventilation Hospitalization 7/13/2009 Male 159 lb 9/8/2009 Netherlands
Primary
Secondary
Concomitant
Ileus Hospitalization 8/19/2009 Male 182 lb 9/16/2009 United States
Primary
Secondary
Concomitant
Sepsis Death 10/13/2009 Germany
Primary
Secondary
Vomiting Other Serious 7/1/1999 Male 10/20/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Hallucination Other Serious 8/6/2009 86 Male 137 lb 11/6/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 1/7/2009 Male 187 lb 11/18/2009 Germany
Primary
Secondary
Concomitant
Syncope Other Serious 5/15/2009 Female 11/18/2009 Physician United States
Primary
Concomitant
Syncope Other Serious 6/16/2008 Female 12/8/2009 Physician United States
Primary
Concomitant
Multiple Myeloma Death 10/21/2009 Male 12/31/2009 Physician United States
Primary
Concomitant
Photopsia Other Serious 9/27/2009 Female 1/12/2010 Physician United States
Primary
Concomitant
Osteonecrosis Other Serious 10/1/2009 Male 160 lb 1/29/2010 Physician United States
Primary
Secondary
Concomitant
Multiple Myeloma Death 10/21/2009 Male 2/12/2010 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 65 Female 2/12/2010 Other Health Professional Belgium
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 10/1/2009 Male 160 lb 2/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 10/1/2009 Male 160 lb 2/17/2010 Physician United States
Primary
Secondary
Concomitant
Multiple Myeloma Other Serious 64 Male 2/25/2010 Spain
Primary
Concomitant
Vomiting Other Serious 7/1/1999 Male 3/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Hospitalization 2/2/2010 69 Male 179 lb 3/2/2010 United States
Primary
Secondary
Concomitant
Multiple Myeloma Other Serious 64 Male 3/4/2010 Spain
Primary
Concomitant
Vomiting Other Serious 7/1/1999 Male 3/10/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 3/11/2010 Other Health Professional Greece
Primary
Secondary
Multiple Myeloma Death 10/21/2009 Male 3/11/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 7/1/1999 Male 3/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2003 Female 3/23/2010 Other Health Professional United States
Primary
Concomitant
Sepsis Other Serious 1/1/2009 50 Male 4/6/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2000 56 Male 4/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 3/29/2010 62 Male 208 lb 4/21/2010 United States
Primary
Secondary
Concomitant
Haematotoxicity Death 1/1/2009 66 Female 4/23/2010 Spain
Primary
Concomitant
Sepsis Other Serious 1/1/2009 50 Male 4/29/2010 Physician United States
Primary
Secondary
Concomitant
Haematotoxicity Death 1/1/2009 66 Male 4/30/2010 Spain
Primary
Concomitant
Haematotoxicity Death 1/1/2009 66 Male 5/3/2010 Spain
Primary
Concomitant
Neuropathy Peripheral Disability 12/1/2009 55 Male 192 lb 5/4/2010 Other Health Professional United Kingdom
Primary
Secondary
Loss Of Consciousness Other Serious 4/27/2010 49 Male 6/1/2010 Physician United States
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 3/29/2010 62 Male 208 lb 6/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2000 56 Male 6/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pyoderma Gangrenosum Other Serious 5/25/2010 80 Male 216 lb 6/30/2010 Physician Netherlands
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 5/31/2010 73 Female 126 lb 7/12/2010 Physician Spain
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2000 56 Male 7/14/2010 United States
Primary
Secondary
Concomitant
Sepsis Other Serious 7/8/2010 73 Male 182 lb 7/19/2010 Other Health Professional United States
Primary
Concomitant
Transaminases Increased Other Serious 7/20/2010 Other Health Professional United States
Primary
Secondary
Osteonecrosis Of Jaw Other Serious 6/28/2010 67 Male 201 lb 7/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vasculitis Hospitalization 1/1/2010 65 Male 8/3/2010 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 7/13/2010 62 Male 207 lb 8/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Disease Progression Death Female 8/6/2010 Physician Canada
Primary
Concomitant
Renal Failure Acute Other Serious 1/1/2009 55 Male 186 lb 8/6/2010 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Other Serious 6/28/2010 67 Male 201 lb 8/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urosepsis Hospitalization 7/15/2010 56 Female 209 lb 8/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 8/18/2010 United States
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 4/26/2010 49 Male 8/23/2010 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 67 Male 8/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/19/2009 62 Male 207 lb 8/31/2010 Other Health Professional France
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Death Male 9/15/2010 Physician Italy
Primary
Concomitant
Neutropenic Sepsis Life Threatening 3/21/2010 71 Male 9/17/2010 Physician United States
Primary
Concomitant
Graft Versus Host Disease Other Serious 9/17/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Vasculitis Hospitalization 1/1/2010 65 Male 9/22/2010 Physician United States
Primary
Secondary
Concomitant
Vasculitis Other Serious 9/24/2010 United States
Primary
Secondary
Concomitant
Wrist Fracture Other Serious 1/1/2010 66 Female 100 lb 9/29/2010 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2003 60 Female 9/29/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 1/1/2000 56 Male 10/4/2010 United States
Primary
Secondary
Concomitant
Pancytopenia Other Serious 8/26/2010 58 Male 10/21/2010 Other Health Professional United States
Primary
Secondary
Wrist Fracture Other Serious 1/1/2010 66 Female 100 lb 10/25/2010 Physician United States
Primary
Concomitant
Acute Graft Versus Host Disease In Liver Death 4/24/2009 57 Male 11/18/2010 Physician Italy
Primary
Concomitant
Wrist Fracture Other Serious 1/1/2010 66 Female 100 lb 11/23/2010 Physician United States
Primary
Concomitant
Osteonecrosis Of Jaw Other Serious 6/28/2010 67 Male 201 lb 12/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Disease Progression Death 12/17/2010 59 Female 245 lb 1/12/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 1/1/2010 42 Male 1/12/2011 Physician Switzerland
Primary
Concomitant
Multiple Myeloma Death 1/1/2010 42 Male 1/17/2011 Physician Switzerland
Primary
Concomitant
Muscular Weakness Hospitalization 12/25/2010 80 Male 153 lb 1/26/2011 Other Health Professional United States
Primary
Secondary
Influenza Like Illness Other Serious 8/18/2003 61 Female 2/7/2011 Other Health Professional United States
Primary
Concomitant
Dyspnoea Hospitalization 8/25/2009 77 Female 165 lb 2/8/2011 Physician United States
Primary
Secondary
Concomitant
Confusional State Other Serious 8/25/2009 77 Female 165 lb 2/9/2011 Physician United States
Primary
Secondary
Concomitant
Pain Hospitalization 12/17/2010 59 Female 245 lb 2/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Joint Sprain Other Serious 1/1/2000 56 Male 2/18/2011 Lawyer United States
Primary
Secondary
Concomitant
Septic Shock Death 2/8/2011 81 Male 150 lb 2/28/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cytolytic Hepatitis Hospitalization 2/14/2011 60 Male 3/3/2011 Physician France
Primary
Secondary
Septic Shock Death 2/8/2011 81 Male 150 lb 3/7/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Disability 5/31/2010 73 Female 126 lb 3/9/2011 Physician Spain
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 8/25/2009 77 Female 165 lb 3/9/2011 Physician United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 56 Male 3/11/2011 France
Primary
Concomitant
Renal Failure Hospitalization 2/26/2011 78 Female 163 lb 3/21/2011 Physician United States
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Other Serious 1/1/2006 3/28/2011 Physician France
Primary
Concomitant
Thrombocytopenia Other Serious 10/4/2010 51 Female 3/30/2011 Japan
Primary
Secondary
Concomitant
Generalised Oedema Other Serious 68 Male 3/30/2011 Other Health Professional United States
Primary
Concomitant
Acute Myeloid Leukaemia Hospitalization 2/26/2011 78 Female 163 lb 4/5/2011 Physician United States
Primary
Secondary
Concomitant
Pulmonary Granuloma Hospitalization 8/18/2003 61 Female 4/6/2011 Physician United States
Primary
Concomitant
Graft Versus Host Disease Other Serious 4/12/2011 Other Health Professional United States
Primary
Secondary
Oral Candidiasis Hospitalization 4/14/2011 Australia
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 5/31/2010 73 Female 126 lb 4/19/2011 Physician Spain
Primary
Secondary
Concomitant
Tremor Other Serious 1/1/2011 57 Male 4/25/2011 Physician United States
Primary
Concomitant
Hypertensive Crisis Disability 5/31/2010 73 Female 126 lb 5/2/2011 Physician Spain
Primary
Secondary
Concomitant
Constipation Hospitalization 1/1/2010 73 Male 246 lb 11/20/2010 Physician United States
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 3/28/2007 55 Female 5/11/2011 Other Health Professional United States
Primary
Secondary
Acute Myeloid Leukaemia Other Serious 9/9/2008 55 5/12/2011 Other Health Professional United States
Primary
Secondary
Squamous Cell Carcinoma Death 4/5/2010 68 5/12/2011 Other Health Professional United States
Primary
Secondary
Malignant Melanoma Other Serious 7/8/2009 60 Male 5/12/2011 Other Health Professional United States
Primary
Secondary
Acute Graft Versus Host Disease In Intestine Other Serious 66 Male 5/12/2011 Physician United States
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease In Intestine Other Serious 64 Female 5/13/2011 Physician United States
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease In Intestine Other Serious 66 Male 5/13/2011 Physician United States
Primary
Secondary
Concomitant
No Therapeutic Response Death 2/1/2011 37 Female 99 lb 5/13/2011 Pharmacist United States
Primary
Concomitant
Overdose Hospitalization 2/14/2011 60 Male 4/18/2011 Physician France
Primary
Secondary
Concomitant
Thyroid Cancer Other Serious 5/4/2009 57 Male 5/17/2011 Other Health Professional United States
Primary
Secondary
Death Death 5/20/2011 Other Health Professional France
Primary
Concomitant
Influenza Like Illness Disability 8/18/2003 61 Female 5/31/2011 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 10/4/2010 51 Female 6/2/2011 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Embolism Death 6/3/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Disease Death 5/2/2011 64 Male 172 lb 6/6/2011 Physician United States
Primary
Concomitant
Neutrophil Count Decreased Required Intervention 6/3/2011 45 Female 145 lb 6/3/2011 Pharmacist United States
Primary
Secondary
Concomitant
Vascular Occlusion Hospitalization 5/27/2011 56 Male 6/10/2011 Physician France
Primary
Secondary
Multiple Myeloma Other Serious 11/12/2009 65 Male 6/20/2011 Physician Switzerland
Primary
Concomitant
Anaemia Other Serious 4/1/2005 56 Male 6/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Hospitalization 6/10/2011 53 Male 176 lb 6/29/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 3/23/2011 58 Male 6/30/2011 Physician France
Primary
Secondary
Brain Neoplasm Hospitalization Male 7/12/2011 Physician France
Primary
Secondary

Drug Data