Bortezomib combined with Zometa

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Toothache Other Serious 3/1/2005 62 Male 2/24/2006 United States
Primary
Concomitant
Osteonecrosis Other Serious 11/9/2005 65 Female 95 lb 4/7/2006 Physician Germany
Primary
Concomitant
Scapula Fracture Hospitalization 4/10/2006 73 Male 193 lb 7/7/2006 Physician Germany
Primary
Concomitant
Hypercalcaemia Other Serious 3/1/2007 53 Male 4/14/2007 Pharmacist United States
Primary
Concomitant
Tooth Extraction Other Serious 10/1/2005 76 Female 4/24/2007 Other Health Professional Italy
Primary
Concomitant
Tooth Extraction Other Serious 10/1/2005 76 Female 4/24/2007 Other Health Professional Italy
Primary
Concomitant
Osteonecrosis Other Serious 10/1/2006 Male 5/14/2007 Physician Germany
Primary
Concomitant
Osteonecrosis Other Serious 10/1/2006 Male 5/14/2007 Physician Germany
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2007 Female 8/15/2007 Physician Germany
Primary
Concomitant
Tooth Extraction Other Serious 45 Female 179 lb 12/10/2007 Physician Turkey
Primary
Concomitant
Pneumonia Other Serious 1/1/2004 Male 8/11/2008 Germany
Primary
Concomitant
Osteonecrosis Life Threatening 6/20/2008 Female 8/11/2008 Other Health Professional Italy
Primary
Concomitant
Tooth Extraction Other Serious 10/1/2004 Female 8/12/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Osteonecrosis Life Threatening 6/20/2008 Female 8/12/2008 Italy
Primary
Concomitant
Sepsis Hospitalization 1/7/2009 Male 187 lb 5/14/2009 Germany
Primary
Concomitant
Ulcer Other Serious 2/1/1997 Male 7/28/2009 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 1/7/2009 Male 187 lb 7/31/2009 Germany
Primary
Secondary
Concomitant
Soft Tissue Infection Life Threatening 7/6/2009 Male 183 lb 8/25/2009 United States
Primary
Secondary
Concomitant
Soft Tissue Infection Life Threatening 7/17/2009 Male 183 lb 8/28/2009 United States
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 7/2/2008 Male 115 lb 10/13/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 7/1/1999 Male 10/20/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 1/7/2009 Male 187 lb 11/18/2009 Germany
Primary
Secondary
Concomitant
Syncope Other Serious 5/15/2009 Female 11/18/2009 Physician United States
Primary
Concomitant
Syncope Other Serious 6/16/2008 Female 12/8/2009 Physician United States
Primary
Concomitant
Urine Output Decreased Hospitalization 7/2/2008 Male 115 lb 1/18/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 7/2/2008 Male 115 lb 1/25/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 10/1/2009 Male 160 lb 1/29/2010 Physician United States
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 7/2/2008 Male 115 lb 2/8/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 10/1/2009 Male 160 lb 2/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 10/1/2009 Male 160 lb 2/17/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 7/1/1999 Male 3/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 10/1/2009 70 Male 3/1/2010 Physician Spain
Primary
Concomitant
Vomiting Other Serious 7/1/1999 Male 3/10/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 7/1/1999 Male 3/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2003 Female 3/23/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 1/1/2000 56 Male 4/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 3/29/2010 62 Male 208 lb 4/21/2010 United States
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 3/29/2010 62 Male 208 lb 6/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2000 56 Male 6/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 4/18/2010 65 Female 166 lb 6/28/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2000 56 Male 7/14/2010 United States
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 4/18/2010 65 Female 166 lb 7/22/2010 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Other Serious 6/28/2010 67 Male 201 lb 7/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 4/18/2010 65 Female 166 lb 7/29/2010 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Other Serious 6/28/2010 67 Male 201 lb 8/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 8/7/2010 57 Female 8/17/2010 Germany
Primary
Secondary
Concomitant
Wrist Fracture Other Serious 1/1/2010 66 Female 100 lb 9/29/2010 Physician United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 7/30/2010 57 Female 9/24/2010 Germany
Primary
Secondary
Concomitant
Hypokalaemia 7/30/2010 57 Female 123 lb 9/24/2010 Physician Germany
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2003 60 Female 9/29/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 1/1/2000 56 Male 10/4/2010 United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/27/2010 71 Male 181 lb 10/13/2010 Physician Germany
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 7/30/2010 57 Female 10/6/2010 Germany
Primary
Secondary
Concomitant
Wrist Fracture Other Serious 1/1/2010 66 Female 100 lb 10/25/2010 Physician United States
Primary
Concomitant
Multiple Myeloma Other Serious 11/3/2010 Other Health Professional United States
Primary
Concomitant
Multiple Myeloma Other Serious Male 11/5/2010 Other Health Professional United States
Primary
Concomitant
Wrist Fracture Other Serious 1/1/2010 66 Female 100 lb 11/23/2010 Physician United States
Primary
Concomitant
Cardiac Arrest Death 11/11/2010 70 Male 254 lb 12/8/2010 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Other Serious 6/28/2010 67 Male 201 lb 12/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 7/30/2010 57 Female 12/14/2010 Germany
Primary
Secondary
Concomitant
Influenza Like Illness Other Serious 8/18/2003 61 Female 2/7/2011 Other Health Professional United States
Primary
Concomitant
Joint Sprain Other Serious 1/1/2000 56 Male 2/18/2011 Lawyer United States
Primary
Secondary
Concomitant
Disease Progression Hospitalization 7/2/2008 37 Male 115 lb 3/8/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Alopecia Other Serious 7/2/2008 37 Male 115 lb 3/18/2011 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Granuloma Hospitalization 8/18/2003 61 Female 4/6/2011 Physician United States
Primary
Concomitant
Heat Stroke Hospitalization 7/30/2010 57 Female 3/29/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Humerus Fracture Hospitalization 5/10/2011 80 Female 168 lb 5/25/2011 Physician Germany
Primary
Concomitant
Altered State Of Consciousness Hospitalization 7/30/2010 57 Female 5/18/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Influenza Like Illness Disability 8/18/2003 61 Female 5/31/2011 Physician United States
Primary
Concomitant
Altered State Of Consciousness Hospitalization 7/30/2010 57 Female 6/6/2011 Physician Germany
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 70 Male 6/14/2011 Physician Spain
Primary
Concomitant
Humerus Fracture Hospitalization 5/10/2011 80 Female 168 lb 6/17/2011 Physician Germany
Primary
Concomitant
Anaemia Other Serious 4/1/2005 56 Male 6/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Pressure Increased Other Serious 10/1/2010 81 Male 6/29/2011 Physician Germany
Primary
Concomitant
Soft Tissue Disorder Other Serious 8/18/2003 61 Female 7/18/2011 Physician United States
Primary
Concomitant
Neuropathy Peripheral Other Serious 1/1/1999 59 Female 187 lb 8/3/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Rotator Cuff Syndrome Other Serious Male 8/4/2011 Lawyer United States
Primary
Secondary
Concomitant
Conjunctivitis Allergic Other Serious Male 8/19/2011 Lawyer United States
Primary
Secondary
Concomitant
Gait Disturbance Hospitalization 73 Female 9/6/2011 Physician Germany
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 2/24/2011 67 Male 234 lb 10/6/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Migraine Hospitalization 1/1/1999 59 Female 187 lb 11/17/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Nuclear Magnetic Resonance Imaging Abnormal Disability 8/18/2003 61 Female 11/22/2011 Other Health Professional United States
Primary
Concomitant
Blood Pressure Increased Other Serious Male 11/24/2011 Physician United States
Primary
Secondary
Concomitant
Sinus Bradycardia Hospitalization Male 1/18/2012 Physician United States
Primary
Secondary
Concomitant
Paraesthesia Hospitalization 73 Female 141 lb 1/19/2012 Physician Germany
Primary
Concomitant
Osteonecrosis Of Jaw Disability 11/1/2011 46 Male 1/23/2012 Other Health Professional Italy
Primary
Concomitant
Thrombocytopenia Other Serious 5/1/2011 75 Male 141 lb 1/26/2012 Physician United States
Primary
Concomitant
Polyneuropathy Hospitalization 73 Female 141 lb 2/10/2012 Physician Germany
Primary
Concomitant
Intervertebral Disc Protrusion Other Serious 1/1/1999 59 Female 187 lb 2/15/2012 Physician United States
Primary
Secondary
Concomitant
Gait Disturbance Hospitalization 7/13/2011 73 Female 141 lb 2/28/2012 Physician Germany
Primary
Concomitant
Decreased Appetite Hospitalization 7/2/2008 37 Male 115 lb 3/7/2012 Physician Japan
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Other Serious 12/1/2010 59 Female 3/7/2012 Other Health Professional Japan
Primary
Concomitant
Arthritis Hospitalization Male 3/7/2012 Consumer United States
Primary
Concomitant
Intervertebral Disc Protrusion Hospitalization 1/1/1999 59 Female 187 lb 3/20/2012 Physician United States
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 1/1/1999 59 Female 187 lb 3/26/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Clostridium Difficile Colitis Other Serious 1/1/1999 59 Female 187 lb 3/30/2012 Consumer United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 3/6/2012 74 Male 174 lb 3/30/2012 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 2/1/2007 70 Male 141 lb 4/3/2012 Physician United States
Primary
Concomitant
Clostridium Difficile Colitis Hospitalization 1/1/1999 59 Female 187 lb 4/4/2012 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Death 1/1/2011 74 Male 141 lb 4/11/2012 Physician United States
Primary
Concomitant
Device Occlusion Other Serious 4/1/2005 56 Male 4/20/2012 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Disability 11/1/2011 46 Male 4/20/2012 Other Health Professional Italy
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 3/6/2012 74 Male 174 lb 4/20/2012 Physician United States
Primary
Secondary
Concomitant
Clostridium Difficile Colitis Hospitalization 1/1/1999 59 Female 187 lb 4/23/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Myalgia Other Serious Male 4/30/2012 Consumer United States
Primary
Secondary
Concomitant
Subileus Hospitalization 4/19/2012 58 Male 5/10/2012 Physician France
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Hospitalization 12/15/2011 49 Male 191 lb 5/23/2012 Physician Germany
Primary
Secondary
Concomitant
Lung Squamous Cell Carcinoma Stage 0 Other Serious 3/2/2009 71 Male 174 lb 5/30/2012 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/20/2012 65 Male 6/7/2012 Physician Japan
Primary
Concomitant
Hypersensitivity Hospitalization Male 6/13/2012 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 3/23/2011 58 Female 232 lb 9/20/2011 Other Health Professional United States
Primary
Concomitant
Tremor Hospitalization Male 6/20/2012 Lawyer United States
Primary
Secondary
Concomitant
Condition Aggravated Hospitalization 3/8/2012 65 Male 6/21/2012 Physician Japan
Primary
Secondary
Concomitant
Blood Creatinine Increased Other Serious 3/8/2012 65 Male 7/3/2012 Physician Japan
Primary
Secondary
Concomitant
Neoplasm Malignant Hospitalization 1/1/1999 59 Female 187 lb 7/17/2012 Consumer United States
Primary
Secondary
Concomitant
Osteosclerosis Other Serious 1/1/1999 59 Female 187 lb 7/23/2012 Lawyer United States
Primary
Secondary
Concomitant
Pericardial Effusion Other Serious Male 7/23/2012 Consumer United States
Primary
Secondary
Concomitant
Blood Pressure Decreased Other Serious 7/2/2008 37 Male 119 lb 8/10/2012 Pharmacist Japan
Primary
Secondary
Concomitant
Blood Pressure Decreased Hospitalization 7/2/2008 37 Male 119 lb 8/13/2012 Physician Japan
Primary
Secondary
Concomitant
Hypovolaemia Hospitalization Male 8/15/2012 Consumer United States
Primary
Secondary
Concomitant
Tooth Abscess Other Serious 8/17/2012 Consumer United States
Primary
Concomitant
Pyrexia Other Serious 1/1/1999 59 Female 187 lb 8/17/2012 Physician United States
Primary
Secondary
Concomitant
Intestinal Dilatation Other Serious Male 8/24/2012 Consumer United States
Primary
Secondary
Concomitant
Anxiety Hospitalization 7/30/2012 62 Male 8/24/2012 Physician France
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 6/3/2012 57 Female 158 lb 9/24/2012 Physician Us
Primary
Secondary
Concomitant
Basal Cell Carcinoma Other Serious 8/20/2012 63 Female 11/6/2012 Physician Fr
Primary
Secondary
Concomitant
Breast Cancer Other Serious 10/11/2012 64 Female 11/1/2012 Physician Fr
Primary
Secondary
Concomitant
Death Death 10/29/2012 51 Male 165 lb 12/20/2012 Consumer Us
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 2/28/2011 60 Male 216 lb 11/6/2012 Consumer Us
Primary
Secondary
Concomitant
Plasma Cell Myeloma Death 8/24/2012 64 Female 11/8/2012 Pharmacist Us
Primary
Concomitant
Viral Infection Hospitalization 10/29/2012 67 Male 187 lb 1/25/2013 Physician De
Primary
Secondary
Concomitant
Traumatic Haemorrhage Hospitalization 10/29/2012 73 Female 160 lb 2/19/2013 Consumer Us
Primary
Secondary
Concomitant
Invasive Ductal Breast Carcinoma Other Serious 10/5/2012 59 Female 11/18/2013 Physician Fr
Primary
Secondary
Concomitant
Thrombocytopenia Death 1/21/2013 57 Male 8/19/2013 Physician Es
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Hospitalization 2/22/2013 76 Female 75 lb 5/26/2013 Consumer Us
Primary
Secondary
Concomitant
Sigmoiditis Hospitalization 10/14/2012 58 Female 4/26/2013 Physician Fr
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 1/20/2013 68 Female 97 lb 8/13/2013 Consumer Us
Primary
Secondary
Concomitant
Plasma Cell Myeloma Life Threatening 11/15/2012 74 Male 177 lb 5/29/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Dysphagia Death 5/1/2013 78 Female 139 lb 5/29/2013 Physician Us
Primary
Concomitant
Lung Disorder Hospitalization 6/4/2013 51 Male 8/29/2013 Physician Fr
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 4/3/2013 63 Female 166 lb 7/23/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Life Threatening 6/17/2013 69 Male 9/11/2013 Physician Fi
Primary
Secondary
Concomitant
Device Dislocation Other Serious Female 119 lb 9/4/2013 Physician Us
Primary
Concomitant
Renal Failure Other Serious 8/8/2011 72 Male 148 lb 8/13/2013 Consumer Us
Primary
Secondary
Concomitant
Sarcoma Of Skin Other Serious 1/2013 68 Male 139 lb 9/30/2013 Physician Gb
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 8/2013 64 Male 72 lb 2/28/2014 Physician Fr
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Hospitalization 8/29/2013 66 Female 173 lb 10/2/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Sarcoma Of Skin Other Serious 1/2013 68 Male 139 lb 10/8/2013 Physician Gb
Primary
Secondary
Concomitant
Toxicity To Various Agents Other Serious 4/2005 57 Male 10/30/2013 Consumer Us
Primary
Secondary
Concomitant
Wound Infection Other Serious Male 178 lb 12/4/2013 Consumer Us
Primary
Secondary
Concomitant

Drug Data