Methotrexate Sodium



Indications and Reactions:

Role Indications Reactions
Primary
Rheumatoid Arthritis 23.0%
Acute Lymphocytic Leukaemia 17.5%
Central Nervous System Lymphoma 14.2%
Bone Sarcoma 6.5%
Diffuse Large B-cell Lymphoma 5.8%
Adult T-cell Lymphoma/leukaemia 4.7%
Product Used For Unknown Indication 4.3%
T-cell Lymphoma 3.1%
Acute Myeloid Leukaemia 2.6%
Chemotherapy 2.1%
Hodgkin's Disease 2.1%
Immunodeficiency 2.1%
Burkitt's Lymphoma 1.8%
Lymphocytic Leukaemia 1.8%
Prophylaxis 1.6%
Hypertension 1.4%
Juvenile Arthritis 1.4%
B Precursor Type Acute Leukaemia 1.3%
Chronic Myeloid Leukaemia 1.3%
Anxiety 1.2%
Drug Hypersensitivity 33.9%
Drug Ineffective 9.5%
Osteonecrosis 5.3%
Rash 4.8%
Toxicity To Various Agents 4.2%
Vomiting 4.2%
Rheumatoid Arthritis 3.7%
Alopecia 3.2%
Pneumonia 3.2%
Pyrexia 3.2%
Bone Marrow Failure 2.6%
Drug Effect Decreased 2.6%
Drug Interaction 2.6%
Hepatic Enzyme Increased 2.6%
Nausea 2.6%
Sepsis 2.6%
Thrombocytopenia 2.6%
Drug Intolerance 2.1%
Leukoencephalopathy 2.1%
Malaise 2.1%
Secondary
Rheumatoid Arthritis 44.0%
Product Used For Unknown Indication 7.1%
Drug Use For Unknown Indication 7.0%
Acute Lymphocytic Leukaemia 6.5%
Adult T-cell Lymphoma/leukaemia 4.3%
Psoriatic Arthropathy 3.8%
Hypertension 3.2%
T-cell Lymphoma Stage Iv 3.2%
Burkitt's Lymphoma 3.1%
Central Nervous System Lymphoma 2.4%
Prophylaxis 2.4%
Juvenile Arthritis 2.0%
Pain 1.8%
Osteoporosis 1.8%
Diffuse Large B-cell Lymphoma 1.4%
T-cell Lymphoma 1.3%
Non-hodgkin's Lymphoma 1.2%
Psoriasis 1.2%
Depression 1.2%
Still's Disease Adult Onset 1.1%
Neutropenia 10.5%
Vomiting 6.4%
Weight Decreased 6.4%
Sepsis 6.0%
Rheumatoid Arthritis 5.8%
Thrombocytopenia 5.8%
Interstitial Lung Disease 4.9%
Pneumonia 4.9%
Pyrexia 4.7%
Drug Hypersensitivity 4.5%
Drug Ineffective 4.5%
Pulmonary Fibrosis 4.5%
Basal Cell Carcinoma 4.3%
Nausea 4.3%
Septic Shock 4.3%
Hepatic Enzyme Increased 4.1%
Spinal Fracture 3.8%
Stomatitis 3.8%
Urinary Tract Infection 3.4%
Viith Nerve Paralysis 3.2%
Concomitant
Rheumatoid Arthritis 41.0%
Drug Use For Unknown Indication 24.9%
Product Used For Unknown Indication 10.7%
Hypertension 3.3%
Psoriatic Arthropathy 3.2%
Osteoporosis 2.3%
Pain 2.1%
Prophylaxis 1.7%
Prophylaxis Against Gastrointestinal Ulcer 1.5%
Vitamin Supplementation 1.3%
Juvenile Arthritis 1.1%
Ankylosing Spondylitis 1.1%
Psoriasis 0.9%
Crohn's Disease 0.8%
Depression 0.8%
Diabetes Mellitus 0.7%
Polyarthritis 0.7%
Coronary Artery Disease 0.7%
Constipation 0.6%
Prophylaxis Against Graft Versus Host Disease 0.6%
Weight Decreased 10.0%
Pyrexia 9.3%
Sepsis 8.6%
Rheumatoid Arthritis 7.9%
Pneumonia 7.0%
Vomiting 7.0%
Urinary Tract Infection 5.6%
Tuberculosis 4.9%
Thrombocytopenia 4.0%
Weight Increased 4.0%
Myocardial Infarction 3.7%
Pulmonary Embolism 3.7%
Respiratory Failure 3.7%
Sinusitis 3.5%
Death 3.3%
Syncope 3.0%
Osteonecrosis 2.8%
Pain 2.8%
Dyspnoea 2.6%
Malignant Melanoma 2.6%
Interacting
Rheumatoid Arthritis 31.4%
Product Used For Unknown Indication 30.2%
Infection 6.5%
Pain 3.6%
Psoriatic Arthropathy 3.0%
Chemotherapy 2.4%
Hypothyroidism 2.4%
Leukaemia 2.4%
Precursor T-lymphoblastic Lymphoma/leukaemia 2.4%
Acute Lymphocytic Leukaemia 1.8%
Candidiasis 1.8%
Essential Hypertension 1.8%
Psoriasis 1.8%
Respiratory Tract Infection 1.8%
Contraception 1.2%
Diabetes Mellitus 1.2%
Febrile Neutropenia 1.2%
Nail Psoriasis 1.2%
Osteosarcoma 1.2%
Smoking Cessation Therapy 1.2%
Drug Interaction 15.9%
Drug Level Increased 11.4%
Toxicity To Various Agents 11.4%
White Blood Cell Count Decreased 9.1%
Inappropriate Schedule Of Drug Administration 6.8%
Psoriasis 6.8%
Supraventricular Tachycardia 6.8%
Epistaxis 4.5%
Pancytopenia 4.5%
Headache 2.3%
Liver Function Test Abnormal 2.3%
Pleural Effusion 2.3%
Pruritus 2.3%
Pulmonary Fibrosis 2.3%
Pyrexia 2.3%
Renal Failure Acute 2.3%
Renal Necrosis 2.3%
Rheumatoid Nodule 2.3%
Scleroderma 2.3%