Methotrexate Sodium combined with Prednisone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Decreased Other Serious 6/1/2005 Female 130 lb 1/6/2006 United States
Primary
Concomitant
Ulcer Other Serious 1/1/2001 49 Female 141 lb 1/24/2006 Lawyer United States
Primary
Concomitant
Sudden Death Death 7/27/2004 Female 2/1/2006 United States
Primary
Concomitant
Sudden Death Death 7/27/2004 Female 2/1/2006 United States
Primary
Concomitant
Muscle Spasms Hospitalization 12/9/2005 Female 176 lb 2/2/2006 Canada
Primary
Secondary
Concomitant
Renal Mass Other Serious 1/13/2005 Male 183 lb 2/21/2006 Physician United States
Primary
Secondary
Concomitant
Cough Other Serious 1/1/2005 Female 220 lb 3/2/2006 Other Health Professional United States
Primary
Concomitant
Rheumatoid Arthritis Life Threatening 9/1/2002 54 Female 190 lb 3/17/2006 Physician Germany
Primary
Secondary
Concomitant
Renal Mass Other Serious 1/13/2005 Male 183 lb 3/30/2006 Physician United States
Primary
Secondary
Concomitant
Pleural Effusion Required Intervention 5/1/2005 75 Male 172 lb 1/16/2006 Other Health Professional United States
Primary
Concomitant
Renal Mass Other Serious 1/13/2005 Male 183 lb 5/30/2006 Physician United States
Primary
Secondary
Concomitant
Sinusitis Other Serious 1/1/2006 Female 146 lb 6/12/2006 Physician United States
Primary
Concomitant
Rib Fracture Other Serious Female 135 lb 6/14/2006 Other Health Professional Canada
Primary
Concomitant
Appendicitis Perforated Hospitalization 5/9/2006 Male 215 lb 7/24/2006 Physician United States
Primary
Concomitant
Renal Mass Other Serious 1/13/2005 Male 183 lb 8/2/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 12/1/2004 Female 175 lb 8/17/2006 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 4/6/2006 54 Female 135 lb 9/22/2006 Other Health Professional Canada
Primary
Concomitant
Rheumatoid Arthritis Other Serious 8/21/2006 45 Male 9/27/2006 Physician Spain
Primary
Concomitant
Rib Fracture Other Serious Female 135 lb 9/27/2006 Physician Canada
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 1/1/2006 Male 190 lb 1/27/2007 Consumer Canada
Primary
Concomitant
Humerus Fracture Other Serious 11/11/2005 Female 163 lb 2/8/2007 Physician Germany
Primary
Concomitant
Tendon Disorder Other Serious 12/1/2005 Female 195 lb 2/15/2007 Consumer Canada
Primary
Concomitant
Skin Ulcer Hospitalization 11/28/2006 70 Female 2/20/2007 Other Health Professional Poland
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Other Serious 1/2/2007 68 Male 3/5/2007 Other Health Professional Portugal
Primary
Secondary
Concomitant
Hepatic Steatosis Other Serious 1/1/2006 Male 190 lb 3/13/2007 Consumer Canada
Primary
Secondary
Concomitant
Vitreous Floaters Required Intervention 1/1/2005 66 Female 254 lb 6/13/2007 Physician United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 11/1/2005 56 Female 313 lb 6/13/2007 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 9/10/2006 49 Female 6/13/2007 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 2/1/2004 45 Female 190 lb 6/13/2007 Physician United States
Primary
Concomitant
Squamous Cell Carcinoma Of Skin Required Intervention 10/27/2006 62 Male 290 lb 6/13/2007 Physician United States
Primary
Secondary
Pharyngolaryngeal Pain Required Intervention 11/1/2006 59 Female 134 lb 6/13/2007 Physician United States
Primary
Concomitant
Mitral Valve Replacement Other Serious Female 7/18/2007 Consumer United States
Primary
Concomitant
Histoplasmosis Other Serious 1/1/2004 75 Female 7/25/2007 Physician United States
Primary
Concomitant
Psoriasis Hospitalization 3/1/2006 Female 207 lb 7/30/2007 Brazil
Primary
Concomitant
Histoplasmosis Other Serious 1/1/2004 75 Female 120 lb 9/17/2007 Physician United States
Primary
Concomitant
Tachycardia Paroxysmal Hospitalization 8/21/2007 Female 126 lb 9/18/2007 Physician Portugal
Primary
Concomitant
Urinary Tract Infection Other Serious 3/6/2007 Female 269 lb 10/8/2007 Physician United States
Primary
Concomitant
Periarthritis Other Serious 10/16/2007 57 Female 12/11/2007 Physician United States
Primary
Concomitant
Arthritis Bacterial Hospitalization 9/15/2004 Female 134 lb 12/19/2007 Germany
Primary
Concomitant
Lymphoproliferative Disorder Hospitalization 1/1/2008 21 Male 4/18/2008 Physician France
Primary
Secondary
Concomitant
Arthritis Bacterial Hospitalization 9/15/2004 Female 134 lb 7/25/2008 Germany
Primary
Concomitant
Pulmonary Mass Other Serious 7/8/2008 Male 8/18/2008 China
Primary
Concomitant
Pain In Jaw Hospitalization 1/1/2008 Female 8/18/2008 Consumer United States
Primary
Concomitant
Serotonin Syndrome Life Threatening 8/26/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 3/1/2007 Female 177 lb 8/26/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 14 Male 9/19/2008 United Kingdom
Primary
Secondary
Concomitant
Malignant Melanoma Other Serious 8/13/2008 Male 176 lb 10/3/2008 Australia
Primary
Concomitant
Visual Acuity Reduced Other Serious 9/22/2006 Female 10/3/2008 Physician United States
Primary
Concomitant
Tachycardia Life Threatening 4/1/2008 Male 220 lb 10/3/2008 France
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2008 Male 146 lb 10/6/2008 United States
Primary
Secondary
Concomitant
Osteoporosis Other Serious Female 10/7/2008 Consumer United States
Primary
Concomitant
Atherectomy Hospitalization Male 250 lb 10/7/2008 Canada
Primary
Concomitant
Thrombocytopenia Other Serious Male 10/8/2008 Physician United States
Primary
Secondary
Concomitant
Pulmonary Fibrosis Other Serious 1/1/2004 Female 10/8/2008 Consumer United States
Primary
Concomitant
Scoliosis Hospitalization 1/21/2008 Female 10/15/2008 Physician United States
Primary
Concomitant
Osteonecrosis Hospitalization 4/1/2005 2/24/2009 Physician Denmark
Primary
Secondary
Diverticulitis Hospitalization 1/2/2009 Male 3/5/2009 Physician United Kingdom
Primary
Secondary
Weight Decreased Other Serious 3/1/2008 Female 170 lb 3/6/2009 Canada
Primary
Secondary
Concomitant
Leukoencephalopathy Other Serious 3/16/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Toothache 8/9/2008 57 Female 3/18/2009 Physician Canada
Primary
Secondary
Concomitant
Pyrexia Hospitalization 12/1/2008 Male 119 lb 3/20/2009 Pharmacist United States
Primary
Concomitant
Osteonecrosis Hospitalization 4/1/2005 3/20/2009 Physician Denmark
Primary
Secondary
Mucosal Inflammation Other Serious 3/20/2009 Physician Japan
Primary
Concomitant
Hepatotoxicity Other Serious 3/20/2009 Physician Japan
Primary
Concomitant
Malignant Melanoma Life Threatening 10/1/2008 3/25/2009 Other Health Professional France
Primary
Secondary
Concomitant
Leukoencephalopathy Other Serious 4/6/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Hemiparesis Hospitalization 54 Female 4/6/2009 Physician United States
Primary
Concomitant
Road Traffic Accident Other Serious 3/22/2009 Male 198 lb 4/7/2009 Physician South Africa
Primary
Concomitant
Infusion Related Reaction Other Serious 1/1/2007 Female 4/10/2009 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2008 Female 150 lb 5/8/2009 Consumer United States
Primary
Concomitant
Malaise Other Serious 1/1/2007 Female 210 lb 5/11/2009 Consumer United States
Primary
Secondary
Concomitant
Malignant Melanoma Other Serious 8/13/2008 Male 176 lb 5/14/2009 Australia
Primary
Concomitant
Syncope Other Serious Female 174 lb 5/27/2009 Physician United States
Primary
Concomitant
Staphylococcal Infection Other Serious 1/1/2003 Male 6/9/2009 Consumer United States
Primary
Concomitant
Temporal Arteritis Other Serious 1/1/2009 Female 102 lb 5/30/2009 Consumer United States
Primary
Concomitant
Teeth Brittle 1/1/2005 Female 195 lb 6/11/2009 United States
Primary
Concomitant
Thirst 2/28/2009 Female 213 lb 6/11/2009 United States
Primary
Concomitant
Skin Fissures 4/1/2009 Female 6/12/2009 United States
Primary
Concomitant
Breast Cancer Life Threatening 1/26/2009 Female 7/2/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Paraesthesia Other Serious 5/15/2008 64 Female 7/13/2009 Physician Australia
Primary
Concomitant
Nerve Compression Other Serious 12/15/2008 78 Female 7/13/2009 Consumer Australia
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2007 Male 161 lb 8/11/2009 Physician United States
Primary
Concomitant
Respiratory Failure Death 8/13/2009 Other Health Professional New Zealand
Primary
Secondary
Coccidioidomycosis Other Serious 8/26/2009 Other Health Professional United States
Primary
Secondary
Pain In Extremity Other Serious 11/16/2008 Female 9/3/2009 Canada
Primary
Concomitant
Urinary Tract Infection Other Serious 5/14/2009 19 Female 139 lb 9/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Injection Site Pain 4/1/2007 Female 112 lb 9/12/2009 United States
Primary
Concomitant
Toothache 8/9/2008 57 Female 9/18/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Feeling Hot 8/24/2009 Female 9/19/2009 United States
Primary
Concomitant
Respiratory Failure Death 9/24/2009 Other Health Professional New Zealand
Primary
Secondary
Pulmonary Hypertension Required Intervention 11/19/2008 32 Female 108 lb 11/24/2008 Pharmacist United States
Primary
Concomitant
Rheumatoid Nodule Other Serious 11/26/2007 Female 166 lb 10/9/2009 Physician Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 6 Female 10/6/2009 United States
Primary
Concomitant
Completed Suicide Death 8/1/2009 Female 196 lb 10/14/2009 United States
Primary
Concomitant
Haemorrhage Other Serious Female 10/30/2009 Other Health Professional United States
Primary
Concomitant
Ileus Other Serious Female 11/6/2009 United States
Primary
Concomitant
Malignant Melanoma Other Serious 9/3/2009 Female 155 lb 11/10/2009 Other Health Professional United States
Primary
Concomitant
Completed Suicide Death 8/1/2009 Female 196 lb 11/16/2009 United States
Primary
Concomitant
Temporal Arteritis Other Serious 1/1/2009 Female 102 lb 12/1/2009 Consumer United States
Primary
Concomitant
Lymphopenia Other Serious 4/29/2009 4 Male 12/17/2009 Physician United States
Primary
Secondary
Toothache Other Serious 8/9/2008 57 Female 12/18/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Neutropenia Other Serious 17 Male 1/6/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ileus Hospitalization 3/3/2008 Female 2/1/2010 United States
Primary
Concomitant
Sinus Disorder Other Serious 8/1/2009 Female 116 lb 2/2/2010 Consumer United States
Primary
Concomitant
Hepatic Steatosis Hospitalization 5/21/2009 Female 143 lb 2/10/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 4/1/2010 72 Female 128 lb 5/27/2010 Pharmacist Australia
Primary
Secondary
Concomitant
Syncope Other Serious 4/1/2010 Female 6/2/2010 Consumer United States
Primary
Secondary
Syncope Other Serious 4/1/2010 Female 6/18/2010 Consumer United States
Primary
Secondary
Thoracic Cavity Drainage Other Serious 1/23/2010 4 Female 39 lb 6/23/2010 Physician Israel
Primary
Secondary
Vomiting Other Serious 6/5/2005 53 Male 174 lb 6/25/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 1/1/2008 46 Female 210 lb 6/28/2010 Consumer United States
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 6/9/2010 64 Female 132 lb 6/29/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 6/5/2005 53 Male 174 lb 7/1/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 9/1/2007 57 Female 157 lb 7/16/2010 Consumer United States
Primary
Secondary
Concomitant
Fall Other Serious 1/1/2010 68 Male 7/20/2010 Physician Canada
Primary
Concomitant
Weight Increased Hospitalization 1/1/2008 8/5/2010 Other Health Professional Algeria
Primary
Concomitant
White Blood Cell Count Increased Other Serious 9/1/2007 57 Female 157 lb 5/18/2010 United States
Primary
Concomitant
Venoocclusive Disease Other Serious 6/1/2010 13 Male 120 lb 8/12/2010 Physician Netherlands
Primary
Concomitant
Vomiting Other Serious 6/5/2005 53 Male 174 lb 8/18/2010 Physician United States
Primary
Concomitant
Venoocclusive Disease Other Serious 6/1/2010 13 Male 120 lb 9/4/2010 Physician Netherlands
Primary
Concomitant
Myocardial Infarction Hospitalization 6/23/2010 44 Male 176 lb 9/15/2010 Physician Germany
Primary
Concomitant
Venoocclusive Disease Other Serious 6/1/2010 13 Male 120 lb 9/16/2010 Physician Netherlands
Primary
Concomitant
Osteoporosis Other Serious 8 Female 9/29/2010 Physician United States
Primary
Secondary
Concomitant
Lip Neoplasm Malignant Stage Unspecified Other Serious 8/1/2010 55 Female 10/7/2010 Physician Albania
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 10/1/2009 63 Female 10/15/2010 Other Health Professional Canada
Primary
Concomitant
Skin Disorder Other Serious 7/12/2010 66 Female 10/26/2010 Physician United States
Primary
Concomitant
Synovial Cyst Other Serious 10/1/2009 53 Female 11/2/2010 Physician Canada
Primary
Secondary
Concomitant
Vertebral Wedging Other Serious 1/1/2000 61 Female 11/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 4/8/2010 14 Male 11/2/2010 Consumer Switzerland
Primary
Secondary
Concomitant
Prostate Cancer Other Serious 10/18/2010 64 Male 112 lb 11/2/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Hepatitis Acute Other Serious 61 Male 11/3/2010 Other Health Professional France
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2008 76 Female 150 lb 11/5/2010 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious Male 144 lb 11/9/2010 Other Health Professional Canada
Primary
Concomitant
Pain In Extremity Other Serious Female 95 lb 11/30/2010 Consumer United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 8/1/2010 70 Female 165 lb 12/2/2010 Consumer United States
Primary
Concomitant
Toothache Other Serious 8/9/2008 57 Female 12/19/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Cataract Other Serious 10/1/2010 78 Female 12/23/2010 Other Health Professional France
Primary
Secondary
Fracture Hospitalization 1/3/2011 Consumer Australia
Primary
Concomitant
Kaposi's Sarcoma Other Serious 1/5/2011 Physician Morocco
Primary
Secondary
Renal Disorder Other Serious 40 Male 1/6/2011 Physician Japan
Primary
Secondary
Kaposi's Sarcoma Other Serious 1/7/2011 Physician Morocco
Primary
Secondary
Completed Suicide Death 1/1/2009 29 Female 1/11/2011 Physician United States
Primary
Secondary
Psychotic Disorder Hospitalization 9/10/2010 65 Female 106 lb 1/14/2011 Physician United States
Primary
Secondary
Concomitant
Diverticular Perforation Hospitalization 9/1/2010 1/20/2011 Consumer Germany
Primary
Secondary
Concomitant
Dyspnoea Death 9/6/2009 76 Female 1/26/2011 Physician Canada
Primary
Concomitant
Vocal Cord Disorder Hospitalization 1/1/2009 56 Female 130 lb 1/27/2011 Consumer Netherlands
Primary
Concomitant
Dyspnoea Other Serious 63 Female 1/30/2011 Consumer Israel
Primary
Concomitant
Death Hospitalization 9/6/2009 76 Female 2/3/2011 Physician Canada
Primary
Concomitant
Cataract Other Serious 10/1/2010 78 Female 2/8/2011 Other Health Professional France
Primary
Secondary
Respiratory Disorder Other Serious 1/19/2011 66 Female 2/14/2011 Other Health Professional Canada
Primary
Concomitant

Drug Data