Acetaminophen combined with Methotrexate Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pulmonary Embolism Hospitalization Male 143 lb 3/7/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pancytopenia Life Threatening 4/20/2006 73 Female 99 lb 7/4/2006 United Kingdom
Primary
Secondary
Concomitant
Vestibulitis Other Serious 10/17/2005 Female 8/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Overdose Hospitalization 11/14/2004 Female 207 lb 8/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pyrexia Hospitalization Male 10/11/2006 Physician Finland
Primary
Concomitant
Urosepsis Hospitalization 8/26/2006 Female 10/23/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/1/2006 Female 7/18/2007 Other Health Professional United Kingdom
Primary
Concomitant
Breast Cancer Other Serious 1/1/2007 Female 141 lb 8/8/2007 Other Health Professional United Kingdom
Primary
Concomitant
Metastases To The Mediastinum Hospitalization 2/21/2008 64 Male 7/23/2008 Other Health Professional Sweden
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 3 Male 7/25/2008 Consumer Canada
Primary
Concomitant
Pneumonia Hospitalization 3/10/2008 Female 181 lb 8/20/2008 United Kingdom
Primary
Concomitant
Sepsis Hospitalization 8/1/2006 Female 190 lb 8/21/2008 Physician Canada
Primary
Secondary
Concomitant
Hyperthyroidism Hospitalization 5/21/2006 89 Female 99 lb 8/22/2008 Other Health Professional United Kingdom
Primary
Concomitant
Electrolyte Imbalance Hospitalization 5/2/2008 56 Male 231 lb 8/22/2008 United States
Primary
Secondary
Concomitant
Hepatic Function Abnormal Hospitalization 7/30/2007 Male 141 lb 8/28/2008 Physician Japan
Primary
Secondary
Concomitant
Unintended Pregnancy Other Serious 5/12/2008 Female 152 lb 10/3/2008 United Kingdom
Primary
Concomitant
Tachycardia Life Threatening 4/1/2008 Male 220 lb 10/3/2008 France
Primary
Concomitant
Ventricular Tachycardia Other Serious 9/29/2007 Male 194 lb 10/6/2008 United Kingdom
Primary
Concomitant
Bladder Transitional Cell Carcinoma Other Serious 6/19/2008 Male 240 lb 10/6/2008 United Kingdom
Primary
Concomitant
Visual Acuity Reduced Other Serious 2/1/2007 Female 10/7/2008 Canada
Primary
Concomitant
Atherectomy Hospitalization Male 250 lb 10/7/2008 Canada
Primary
Concomitant
Haemoptysis Hospitalization 10/1/2008 55 Female 10/8/2008 Consumer Thailand
Primary
Concomitant
Death Other Serious Female 168 lb 10/17/2008 Other Health Professional United Kingdom
Primary
Concomitant
Malaise Other Serious 1/1/2007 Female 210 lb 5/11/2009 Consumer United States
Primary
Secondary
Concomitant
Nausea Other Serious 1/1/2009 Female 9/29/2009 Other Health Professional Australia
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 11/21/2009 72 Female 4/20/2010 United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 11/21/2009 72 Female 6/7/2010 United States
Primary
Concomitant
Myocardial Infarction Life Threatening 6/9/2010 64 Female 132 lb 6/29/2010 Physician United States
Primary
Secondary
Concomitant
Basal Cell Carcinoma Life Threatening 3/16/2010 70 Female 8/13/2010 Other Health Professional France
Primary
Secondary
Concomitant
Spinal Osteoarthritis Hospitalization 3/16/2010 71 Female 8/26/2010 Physician Germany
Primary
Concomitant
Liver Disorder Hospitalization 7/5/2010 53 Female 121 lb 9/10/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 11/21/2009 72 Female 9/3/2010 United States
Primary
Concomitant
Productive Cough Hospitalization 8/1/2010 74 Female 168 lb 9/13/2010 Physician Germany
Primary
Concomitant
Neoplasm Hospitalization 7/25/2008 61 Female 11/2/2010 Physician United Kingdom
Primary
Concomitant
Tuberculosis Other Serious 1/1/1997 46 Female 11/4/2010 Physician Colombia
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/1/2010 60 Female 11/22/2010 Physician United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 11/21/2009 72 Female 12/23/2010 United States
Primary
Concomitant
Lung Neoplasm Malignant Other Serious Female 3/25/2011 Physician United States
Primary
Concomitant
Decreased Appetite Hospitalization 7/1/2010 60 Female 160 lb 3/26/2011 Lawyer United States
Primary
Secondary
Concomitant
Nasal Congestion Hospitalization 11/21/2009 72 Female 3/18/2011 Other Health Professional United States
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 7/16/2010 34 Female 132 lb 5/18/2011 Physician Belgium
Primary
Secondary
Concomitant
Langerhans' Cell Histiocytosis Hospitalization 1/1/2011 60 Male 198 lb 6/1/2011 Physician Denmark
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 3/17/2011 60 Female 6/2/2011 Physician France
Primary
Secondary
Concomitant
Langerhans' Cell Histiocytosis Hospitalization 1/1/2011 60 Male 198 lb 6/16/2011 Physician Denmark
Primary
Secondary
Concomitant
Langerhans' Cell Histiocytosis Hospitalization 1/1/2011 60 Male 198 lb 6/16/2011 Physician Denmark
Primary
Secondary
Concomitant
Lymphocytosis Other Serious 4/6/2010 29 Female 6/17/2011 Physician France
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 4/29/2011 56 Male 6/24/2011 Other Health Professional United States
Primary
Concomitant
Pancytopenia Hospitalization 4/29/2010 56 Male 6/29/2011 Other Health Professional United States
Primary
Concomitant
Pancytopenia Hospitalization 4/29/2010 56 Male 6/30/2011 Other Health Professional United States
Primary
Concomitant
Musculoskeletal Chest Pain Hospitalization 4/28/2010 58 Male 6/30/2011 Other Health Professional France
Primary
Secondary
Infection Hospitalization 5/23/2011 50 Female 143 lb 7/22/2011 Physician New Zealand
Primary
Secondary
Concomitant
Langerhans' Cell Histiocytosis Hospitalization 1/1/2011 60 Male 198 lb 7/26/2011 Physician Denmark
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 5/23/2011 50 Female 143 lb 8/11/2011 Physician New Zealand
Primary
Secondary
Concomitant
Fatigue Other Serious 1/1/2009 56 Male 9/6/2011 Consumer Finland
Primary
Concomitant
Hypokalaemia Hospitalization 1/1/2009 56 Male 9/9/2011 Consumer Finland
Primary
Concomitant
Hypokalaemia Other Serious 1/1/2009 56 Male 9/14/2011 Consumer Finland
Primary
Concomitant
Cardiac Arrest Hospitalization 7/9/2002 81 Male 154 lb 9/19/2011 Physician Switzerland
Primary
Concomitant
Interacting
Aortic Elongation Hospitalization 5/1/2011 72 Female 9/20/2011 Physician Spain
Primary
Concomitant
Keratitis Interstitial Other Serious 1/1/2011 54 Female 198 lb 9/27/2011 Physician France
Primary
Concomitant
Arthralgia Other Serious 1/1/2009 44 Male 10/17/2011 Physician Norway
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2009 44 Male 10/20/2011 Physician Norway
Primary
Secondary
Concomitant
Posterior Reversible Encephalopathy Syndrome Hospitalization 10/8/2011 9 Male 57 lb 10/21/2011 Physician Czech Republic
Primary
Secondary
Concomitant
Juvenile Arthritis Other Serious 5/12/2011 10 Male 74 lb 10/24/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Activities Of Daily Living Impaired Other Serious 1/1/2009 44 Male 11/18/2011 Physician Norway
Primary
Secondary
Concomitant
Headache Hospitalization 1/1/2011 46 Female 11/23/2011 Consumer Brazil
Primary
Concomitant
Gait Disturbance Other Serious 1/1/2010 59 Female 172 lb 11/23/2011 Physician United States
Primary
Concomitant
Trismus Hospitalization 1/1/2009 44 Male 11/27/2011 Physician Norway
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 12/4/1996 2 Male 29 lb 11/28/2011 Other Health Professional Germany
Primary
Secondary
Ascites Other Serious 12/4/1996 2 Male 29 lb 12/12/2011 Physician Germany
Primary
Secondary
Rectal Haemorrhage Other Serious 1/1/2009 44 Male 12/20/2011 Physician Norway
Primary
Secondary
Concomitant
Constipation Hospitalization Female 12/23/2011 Other Health Professional France
Primary
Concomitant
Dyspnoea Hospitalization 12/16/2011 66 Female 12/26/2011 Consumer Canada
Primary
Concomitant
Hepatic Cirrhosis Other Serious 9/14/2011 80 Female 12/29/2011 Other Health Professional France
Primary
Secondary
Arthralgia Hospitalization 1/1/2009 44 Male 1/2/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Lymphadenopathy Other Serious 5/1/2011 55 Female 1/3/2012 Physician France
Primary
Secondary
Concomitant
Hodgkin's Disease Stage Iii Other Serious 5/1/2011 55 Female 1/6/2012 Other Health Professional France
Primary
Secondary
Concomitant
Hepatic Cirrhosis Hospitalization 9/14/2011 80 Female 1/10/2012 Other Health Professional France
Primary
Secondary
Anaemia Hospitalization 1/1/2011 78 Male 1/13/2012 Other Health Professional France
Primary
Concomitant
Atrioventricular Block Second Degree Hospitalization 12/1/2011 4 Male 1/12/2012 Physician France
Primary
Secondary
Productive Cough Hospitalization 12/16/2011 66 Female 1/29/2012 Consumer Canada
Primary
Concomitant
Weight Decreased Other Serious 3/12/2011 14 Female 83 lb 2/6/2012 France
Primary
Secondary
Concomitant
Flank Pain 7/25/2011 74 Female 160 lb 12/20/2011 Consumer United States
Primary
Concomitant
Psoriatic Arthropathy Other Serious 45 Male 3/12/2012 Consumer Netherlands
Primary
Concomitant
Hypotension Life Threatening 10/25/2011 70 Male 3/13/2012 Physician Spain
Primary
Secondary
Concomitant
Oliguria Other Serious 10/25/2011 70 Male 3/14/2012 Physician Spain
Primary
Secondary
Concomitant
Peripheral Arterial Occlusive Disease Other Serious 1/1/2012 71 Female 110 lb 3/26/2012 Physician Finland
Primary
Secondary
Concomitant
Sinusitis Hospitalization 11/3/2011 59 Male 3/28/2012 Other Health Professional France
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/12/2012 71 Female 4/3/2012 Other Health Professional France
Primary
Concomitant
Nausea Other Serious 1/2/2012 41 Male 4/3/2012 Other Health Professional France
Primary
Concomitant
Hepatitis Cholestatic Hospitalization 11/3/2011 59 Male 4/4/2012 Physician France
Primary
Secondary
Concomitant
Langerhans' Cell Histiocytosis Hospitalization 1/1/2011 60 Male 198 lb 4/6/2012 Physician Denmark
Primary
Secondary
Concomitant
Amaurosis Disability 3/1/2012 39 Female 4/6/2012 Other Health Professional France
Primary
Concomitant
Pain Hospitalization 2/1/2012 59 Female 4/11/2012 Physician France
Primary
Secondary
Concomitant
Agranulocytosis Hospitalization 3/14/2012 58 Female 4/16/2012 Physician France
Primary
Secondary
Concomitant
Malignant Respiratory Tract Neoplasm Life Threatening 11/1/2011 55 Male 4/16/2012 Physician Sweden
Primary
Secondary
Concomitant
Headache Other Serious 3/14/2012 58 Female 4/17/2012 Other Health Professional France
Primary
Secondary
Concomitant
Asthenia Other Serious 3/14/2012 58 Female 4/24/2012 Other Health Professional France
Primary
Secondary
Concomitant
Iron Deficiency Anaemia Hospitalization 12/1/2011 66 Female 4/25/2012 Physician Switzerland
Primary
Secondary
Concomitant
Asthenia Hospitalization 8/1/2011 81 Female 4/30/2012 Physician Switzerland
Primary
Secondary
Concomitant
Atrioventricular Block Second Degree Hospitalization 12/1/2011 4 Male 4/26/2012 Physician France
Primary
Secondary
Leukaemia Other Serious 11/24/2011 75 Male 5/2/2012 Physician Sweden
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 7/31/2011 73 Female 5/3/2012 Physician Spain
Primary
Concomitant
Interacting
Renal Failure Acute Hospitalization 7/31/2011 73 Female 5/4/2012 Other Health Professional Spain
Primary
Secondary
Concomitant
Atrioventricular Block Second Degree Hospitalization 12/4/2011 4 Male 5/2/2012 Physician France
Primary
Secondary
Oedema Peripheral Life Threatening 2/17/2012 58 Female 5/11/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Confusional State Hospitalization 7/31/2011 73 Female 5/15/2012 Physician Spain
Primary
Concomitant
Interacting
Hepatic Enzyme Increased Other Serious 5/1/2008 67 Female 5/17/2012 Other Health Professional Denmark
Primary
Secondary
Concomitant
Atypical Mycobacterial Lymphadenitis Hospitalization 9/7/2011 4 Female 35 lb 5/18/2012 Physician Norway
Primary
Concomitant
Chills Hospitalization 3/14/2012 58 Female 5/21/2012 Physician France
Primary
Secondary
Concomitant
Depression Other Serious 2/1/2012 59 Female 6/11/2012 Physician United States
Primary
Secondary
Concomitant
Agranulocytosis Other Serious 2/17/2012 58 Female 6/12/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Abscess Other Serious 1/1/2010 69 Female 6/14/2012 Other Health Professional France
Primary
Secondary
Concomitant
Skin Fissures Other Serious 7/21/2011 61 Female 214 lb 6/26/2012 Other Health Professional United Kingdom
Primary
Concomitant
Restless Legs Syndrome Hospitalization 1/1/2010 52 Female 6/28/2012 Other Health Professional France
Primary
Secondary
Concomitant
Genital Ulceration Hospitalization 5/29/2012 57 Female 6/28/2012 Physician France
Primary
Secondary
Abscess Hospitalization 1/1/2010 69 Female 6/28/2012 Other Health Professional France
Primary
Secondary
Concomitant
Epstein-barr Virus Associated Lymphoma Hospitalization 1/1/2010 69 Female 7/5/2012 Other Health Professional France
Primary
Secondary
Concomitant
Inflammation Hospitalization 4/4/2012 77 Female 7/8/2012 Other Health Professional France
Primary
Secondary
Concomitant
Treatment Failure Hospitalization 12/1/2011 60 Female 6/28/2012 Other Health Professional France
Primary
Secondary
Concomitant
Amaurosis Disability 3/1/2012 39 Female 7/12/2012 Other Health Professional France
Primary
Concomitant
Asthenia Other Serious 3/14/2012 58 Female 7/16/2012 Physician France
Primary
Secondary
Concomitant
Chronic Hepatitis Other Serious Female 7/18/2012 Other Health Professional Sweden
Primary
Concomitant
Agitation Other Serious 2/1/2012 59 Female 7/18/2012 Physician France
Primary
Secondary
Concomitant
Decreased Appetite Other Serious 4/4/2012 77 Female 7/19/2012 Other Health Professional France
Primary
Secondary
Concomitant
Prostate Cancer Life Threatening 1/23/2011 69 Male 7/19/2012 Other Health Professional France
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization Female 7/20/2012 Other Health Professional Sweden
Primary
Concomitant
Oedema Peripheral Hospitalization 3/14/2012 58 Female 7/24/2012 Other Health Professional France
Primary
Secondary
Concomitant
Hepatic Steatosis Hospitalization 3/1/2012 Female 7/26/2012 Other Health Professional Sweden
Primary
Concomitant
Bone Marrow Failure Other Serious 3/14/2012 58 Female 7/30/2012 Other Health Professional France
Primary
Secondary
Concomitant
Immunosuppression Other Serious 1/1/2010 68 Female 119 lb 8/1/2012 Other Health Professional France
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 6/2/2012 79 Female 122 lb 7/19/2012 Pharmacist
Primary
Secondary
Concomitant
Fatigue Other Serious 44 Female 8/2/2012 Consumer Netherlands
Primary
Concomitant
Atypical Mycobacterial Lymphadenitis Hospitalization 9/7/2011 4 Female 35 lb 8/6/2012 Physician Norway
Primary
Concomitant
Toxicity To Various Agents Hospitalization 3/14/2012 58 Female 7/22/2012 Physician France
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/2/2012 41 Male 8/10/2012 Other Health Professional France
Primary
Concomitant
Lacunar Infarction Other Serious 5/28/2012 74 Female 8/10/2012 Physician Spain
Primary
Concomitant
Dyspnoea Other Serious 1/1/2011 8 Female 51 lb 8/13/2012 Consumer United States
Primary
Concomitant
Dysarthria Other Serious 7/1/2010 71 Female 8/16/2012 Other Health Professional France
Primary
Concomitant
Interacting
Respiratory Tract Infection Hospitalization 9/7/2011 4 Female 35 lb 8/20/2012 Physician Norway
Primary
Concomitant
Antipsychotic Drug Level Increased Other Serious 7/1/2010 71 Female 8/23/2012 Other Health Professional France
Primary
Concomitant
Interacting
Systolic Dysfunction Hospitalization 7/18/2012 47 Male 8/23/2012 Other Health Professional France
Primary
Secondary
Concomitant
Systolic Dysfunction Other Serious 5/25/2012 47 Male 8/27/2012 Physician France
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 6/2/2012 79 Female 122 lb 8/28/2012 Pharmacist Country Not Specified
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 2012 56 Female 154 lb 9/20/2013 Physician Us
Primary
Concomitant
Presyncope Other Serious 7/14/2012 7 Female 52 lb 1/22/2013 Physician Gb
Primary
Secondary
Concomitant
Sarcoma Other Serious Male 222 lb 3/1/2013 Other Health Professional Us
Primary
Concomitant
Thrombocytopenia Other Serious 11/12/2012 9 Male 2/22/2013 Physician Us
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 11/12/2012 9 Male 2/22/2013 Physician Us
Primary
Secondary
Concomitant
Latent Tuberculosis Other Serious 10/4/2012 53 Female 3/4/2013 Consumer Co
Primary
Secondary
Concomitant
Disseminated Tuberculosis Other Serious 8/13/2013 55 Female 121 lb 9/11/2013 Physician Mx
Primary
Secondary
Concomitant

Drug Data