Methotrexate Sodium combined with Omeprazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Hospitalization 1/12/2006 Female 132 lb 1/27/2006 Japan
Primary
Concomitant
Pyrexia Hospitalization 7/1/2004 64 Female 2/8/2006 Germany
Primary
Concomitant
Pulmonary Embolism Hospitalization 10/14/2005 Female 276 lb 3/31/2006 Consumer United Kingdom
Primary
Concomitant
Tachycardia Hospitalization 1/12/2006 Female 132 lb 4/12/2006 Japan
Primary
Concomitant
Pulmonary Embolism Hospitalization 10/14/2005 Female 276 lb 5/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Endodontic Procedure Other Serious 5/4/2006 Female 112 lb 5/11/2006 Consumer Canada
Primary
Concomitant
Cardiac Failure Hospitalization 1/12/2006 Female 132 lb 6/22/2006 Japan
Primary
Concomitant
Alveolitis Fibrosing Other Serious 4/20/2005 Male 150 lb 7/28/2006 Other Health Professional United Kingdom
Primary
Concomitant
Endodontic Procedure Other Serious 5/4/2006 Female 112 lb 7/28/2006 Consumer Canada
Primary
Concomitant
Thrombosis Other Serious 7/1/2004 64 Female 8/18/2006 Physician Germany
Primary
Concomitant
Rheumatoid Arthritis Other Serious 8/21/2006 45 Male 9/27/2006 Physician Spain
Primary
Concomitant
Urinary Tract Infection Other Serious 1/31/2006 Female 130 lb 10/19/2006 Other Health Professional United Kingdom
Primary
Concomitant
Septic Shock Life Threatening 12/30/2005 Male 10/20/2006 Physician United States
Primary
Secondary
Concomitant
Synovitis Hospitalization 8/28/2006 Female 150 lb 10/27/2006 Physician Czech Republic
Primary
Concomitant
Eczema Hospitalization 9/1/2006 Female 121 lb 10/27/2006 Italy
Primary
Concomitant
Congestive Cardiomyopathy Disability 1/17/2006 Male 137 lb 11/9/2006 Physician Germany
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 4/20/2005 Male 150 lb 11/29/2006 Other Health Professional United Kingdom
Primary
Concomitant
Guillain-barre Syndrome Hospitalization 8/4/2006 Male 12/15/2006 Physician United States
Primary
Concomitant
Spinal Fusion Surgery Hospitalization 12/1/2006 Female 12/15/2006 Other Health Professional Canada
Primary
Concomitant
Cardiac Failure Hospitalization 1/12/2006 Female 132 lb 1/18/2007 Japan
Primary
Concomitant
Prostate Cancer Hospitalization 10/16/2006 Male 183 lb 2/15/2007 Physician Germany
Primary
Secondary
Concomitant
Neutropenic Sepsis Other Serious 12/20/2006 18 Male 2/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenic Sepsis Other Serious 12/20/2006 18 Male 3/20/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenic Sepsis Other Serious 12/20/2006 18 Male 4/2/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pyrexia Other Serious 4/8/2007 59 Female 4/16/2007 Other Health Professional Mexico
Primary
Secondary
Concomitant
Urine Analysis Abnormal Hospitalization 3/1/2007 Female 5/1/2007 Physician Belgium
Primary
Concomitant
Urine Analysis Abnormal Hospitalization 3/1/2007 Female 5/15/2007 Physician Belgium
Primary
Concomitant
Basal Cell Carcinoma Other Serious 3/1/2007 Male 163 lb 6/1/2007 Physician Canada
Primary
Secondary
Concomitant
Basal Cell Carcinoma Other Serious 3/1/2007 Male 163 lb 6/1/2007 Physician Canada
Primary
Secondary
Concomitant
Hypertrophic Cardiomyopathy Hospitalization 4/17/2007 8 Male 57 lb 6/1/2007 Other Health Professional France
Primary
Secondary
Knee Arthroplasty Other Serious 2/1/2007 44 Female 6/1/2007 Consumer Brazil
Primary
Concomitant
Syncope Hospitalization 4/12/2006 Female 143 lb 6/1/2007 Physician United Kingdom
Primary
Concomitant
Intermittent Claudication Hospitalization 3/1/2007 Male 43 lb 6/6/2007 France
Primary
Concomitant
Intestinal Haemorrhage Hospitalization 5/3/2007 70 Female 115 lb 5/31/2007 Consumer Brazil
Primary
Concomitant
Respiratory Failure Life Threatening 5/28/2007 58 Male 6/7/2007 Physician Spain
Primary
Concomitant
Non-hodgkin's Lymphoma Stage I Other Serious 1/1/2007 Male 165 lb 6/11/2007 Physician Netherlands
Primary
Secondary
Concomitant
Rash Other Serious 1/1/2004 Female 97 lb 6/21/2007 Consumer United States
Primary
Concomitant
Rash Other Serious 1/1/2004 Female 99 lb 6/29/2007 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 3/1/2004 Female 157 lb 7/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 4/20/2005 Male 150 lb 7/25/2007 Other Health Professional United Kingdom
Primary
Concomitant
Large Intestine Perforation Hospitalization 2/7/2006 Male 209 lb 8/8/2007 Netherlands
Primary
Concomitant
Tachycardia Paroxysmal Hospitalization 8/21/2007 Female 126 lb 9/18/2007 Physician Portugal
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 12/25/2004 Female 132 lb 11/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Prostate Cancer Stage Ii Hospitalization 11/13/2006 Male 183 lb 2/8/2008 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 3/28/2008 59 Female 5/1/2008 Other Health Professional France
Primary
Secondary
Weight Decreased Hospitalization 3/28/2008 59 Female 5/5/2008 Other Health Professional France
Primary
Secondary
Weight Decreased Other Serious 3/28/2008 59 Female 5/8/2008 France
Primary
Secondary
Weight Decreased Hospitalization 3/28/2008 Female 5/12/2008 Other Health Professional France
Primary
Secondary
Retinal Detachment Hospitalization 10/21/2003 Male 258 lb 7/15/2008 United Kingdom
Primary
Concomitant
Pericarditis Hospitalization 5/7/2008 Male 7/23/2008 Other Health Professional Sweden
Primary
Concomitant
Vomiting Hospitalization 11/1/2007 79 Female 7/18/2008 Consumer Colombia
Primary
Concomitant
Leukocytosis Hospitalization 4/23/2007 Female 115 lb 7/24/2008 Physician United Kingdom
Primary
Concomitant
Sepsis Death Female 198 lb 8/12/2008 United Kingdom
Primary
Concomitant
Pulmonary Mass Other Serious 7/8/2008 Male 8/18/2008 China
Primary
Concomitant
Respiratory Tract Infection Viral Hospitalization 7/28/2008 78 Female 8/20/2008 Physician Spain
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious Male 8/20/2008 Pharmacist Ireland
Primary
Concomitant
Weight Decreased Other Serious 7/11/2008 Male 150 lb 8/28/2008 Other Health Professional United Kingdom
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 7/30/2007 Male 141 lb 8/28/2008 Physician Japan
Primary
Secondary
Concomitant
Tonsil Cancer Other Serious 61 Male 9/8/2008 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 7/11/2008 Male 150 lb 10/6/2008 Other Health Professional United Kingdom
Primary
Concomitant
Visual Acuity Reduced Other Serious 2/1/2007 Female 10/7/2008 Canada
Primary
Concomitant
Haemoptysis Hospitalization 10/1/2008 55 Female 10/8/2008 Consumer Thailand
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious 8/1/2008 58 Female 10/8/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Tendon Rupture Other Serious 1/1/2008 Female 138 lb 10/9/2008 United States
Primary
Secondary
Concomitant
Anosmia Disability Male 159 lb 12/10/2008 Physician Germany
Primary
Concomitant
Hepatic Function Abnormal Death 12/29/2008 Other Health Professional Australia
Primary
Secondary
Meningitis Meningococcal Other Serious 10/1/2008 Male 176 lb 3/13/2009 United States
Primary
Concomitant
Potentiating Drug Interaction Hospitalization 9/8/2008 74 Female 3/12/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Vomiting Life Threatening 3/18/2009 Other Health Professional United Kingdom
Primary
Concomitant
Hepatic Function Abnormal Death 4/3/2009 Other Health Professional Australia
Primary
Secondary
Optic Neuritis Other Serious 8/1/2008 Female 5/13/2009 Physician Argentina
Primary
Concomitant
Optic Neuritis Other Serious 8/1/2008 Female 5/18/2009 Physician Argentina
Primary
Concomitant
Staphylococcal Infection Other Serious 5/15/2009 Female 205 lb 8/26/2009 United Kingdom
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 3/1/2009 80 Female 8/24/2009 Physician Germany
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 3/1/2009 80 Female 130 lb 8/27/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 3/1/2009 80 Female 8/25/2009 Germany
Primary
Concomitant
Polymyalgia Rheumatica Hospitalization 12/4/2008 Female 83 lb 8/31/2009 Japan
Primary
Concomitant
Optic Neuritis Other Serious 8/1/2008 Female 8/31/2009 Physician Argentina
Primary
Concomitant
Sudden Cardiac Death Death 12/3/2008 Male 9/14/2009 Germany
Primary
Concomitant
Weight Decreased Other Serious 4/1/2009 63 9/25/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Appendicitis Other Serious 7/8/2009 Female 137 lb 9/30/2009 Germany
Primary
Concomitant
Osteochondrosis Other Serious 7/9/2009 Female 10/23/2009 Germany
Primary
Concomitant
Septic Arthritis Staphylococcal Hospitalization 6/1/2009 Male 229 lb 10/28/2009 Germany
Primary
Concomitant
Whipple's Disease Other Serious 4/1/2009 63 Female 136 lb 11/20/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pyrexia 5/2/2009 Female 11/25/2009 Physician United States
Primary
Concomitant
Hepatic Steatosis Hospitalization 5/21/2009 Female 143 lb 2/10/2010 Physician United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 11/21/2009 72 Female 4/20/2010 United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 11/21/2009 72 Female 6/7/2010 United States
Primary
Concomitant
Squamous Cell Carcinoma Hospitalization 1/25/2010 65 Female 148 lb 6/25/2010 Physician Germany
Primary
Secondary
Concomitant
Cardiomyopathy Hospitalization 1/25/2010 67 Female 115 lb 8/4/2010 Physician Brazil
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 6/1/2010 13 Male 120 lb 8/12/2010 Physician Netherlands
Primary
Concomitant
Pulmonary Oedema Hospitalization 7/16/2010 61 Male 124 lb 8/23/2010 Physician Spain
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 6/1/2010 13 Male 120 lb 9/4/2010 Physician Netherlands
Primary
Concomitant
General Physical Health Deterioration Hospitalization 12/15/2009 77 Male 165 lb 9/6/2010 Physician France
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 11/21/2009 72 Female 9/3/2010 United States
Primary
Concomitant
Venoocclusive Disease Other Serious 6/1/2010 13 Male 120 lb 9/16/2010 Physician Netherlands
Primary
Concomitant
Pneumonia Life Threatening 9/1/2010 78 Male 194 lb 10/27/2010 Physician Australia
Primary
Secondary
Concomitant
Tuberculosis Other Serious 1/1/1997 46 Female 11/4/2010 Physician Colombia
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 69 Female 11/10/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neuroendocrine Carcinoma Death 9/1/2010 65 Female 11/23/2010 Physician Italy
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 12/15/2009 77 Male 165 lb 11/29/2010 Physician France
Primary
Secondary
Concomitant
Pain In Extremity Other Serious Female 95 lb 11/30/2010 Consumer United Kingdom
Primary
Concomitant
General Physical Health Deterioration Hospitalization 12/15/2009 77 Male 165 lb 12/9/2010 Physician France
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2010 69 Female 12/9/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pain In Extremity 3/15/2010 12/19/2010 Physician United States
Primary
Concomitant
Somnolence Other Serious 1/1/2010 12/22/2010 Consumer Brazil
Primary
Secondary
Concomitant
Musculoskeletal Stiffness 12/23/2010 Physician United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 11/21/2009 72 Female 12/23/2010 United States
Primary
Concomitant
Psychotic Disorder Hospitalization 9/10/2010 65 Female 106 lb 1/14/2011 Physician United States
Primary
Secondary
Concomitant
Vocal Cord Disorder Hospitalization 1/1/2009 56 Female 130 lb 1/27/2011 Consumer Netherlands
Primary
Concomitant
Psychotic Disorder Hospitalization 9/10/2010 65 Female 106 lb 1/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 12/15/2009 77 Male 165 lb 3/23/2011 Physician France
Primary
Concomitant
Cellulitis Hospitalization 4/16/2009 55 Female 187 lb 3/28/2011 Physician Germany
Primary
Secondary
Concomitant
Cellulitis Hospitalization 4/16/2009 55 Female 187 lb 3/28/2011 Physician Germany
Primary
Secondary
Concomitant
Nasal Congestion Hospitalization 11/21/2009 72 Female 3/18/2011 Other Health Professional United States
Primary
Concomitant
Bacterial Sepsis Life Threatening 1/1/2010 52 Male 5/9/2011 Other Health Professional France
Primary
Secondary
Concomitant
Drug Hypersensitivity Hospitalization 9/6/2010 29 Male 5/9/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ataxia Disability 9/1/2010 52 Female 5/20/2011 Physician France
Primary
Secondary
Concomitant
Cerebellar Syndrome Other Serious 9/1/2010 52 Female 5/23/2011 Physician France
Primary
Secondary
Concomitant
Breast Cancer Hospitalization 6/1/2010 46 Female 154 lb 5/24/2011 Other Health Professional Belgium
Primary
Secondary
Concomitant
Paralysis Other Serious 59 Female 176 lb 6/1/2011 Consumer Brazil
Primary
Secondary
Concomitant
Sinusitis Disability 12/1/2008 51 Female 6/2/2011 Other Health Professional France
Primary
Secondary
Concomitant
Lymphocytosis Other Serious 4/6/2010 29 Female 6/17/2011 Physician France
Primary
Secondary
Concomitant
Depression Other Serious 4/1/2011 72 Female 6/17/2011 Consumer Switzerland
Primary
Secondary
Concomitant
Wrist Surgery Other Serious 6/8/2011 34 Female 6/21/2011 Consumer Netherlands
Primary
Concomitant
Abortion Other Serious 33 Female 6/23/2011 Consumer Netherlands
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 11/25/2009 50 Female 159 lb 7/6/2011 Physician Germany
Primary
Secondary
Concomitant
Dizziness Other Serious 5/1/2011 60 Female 7/21/2011 Consumer Netherlands
Primary
Concomitant
Renal Failure Acute Hospitalization 1/25/2011 69 Female 5/24/2011 Chile
Primary
Concomitant
Ataxia Other Serious 9/1/2010 52 Female 8/17/2011 Physician France
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 10/1/2010 20 Female 117 lb 8/18/2011 Other Health Professional France
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/31/2011 81 Male 154 lb 9/1/2011 Physician France
Primary
Secondary
Concomitant
Wound Infection Hospitalization 2/9/2009 64 Female 9/2/2011 Physician Germany
Primary
Concomitant
Encephalitis Viral Hospitalization 8/19/2011 68 Male 127 lb 9/7/2011 Physician Japan
Primary
Secondary
Concomitant
Urinary Retention Other Serious Female 9/13/2011 Other Health Professional Germany
Primary
Concomitant
Generalised Oedema Other Serious 3/5/2010 Female 170 lb 9/16/2011 Physician Germany
Primary
Concomitant
Meniscus Lesion Hospitalization Male 9/21/2011 Consumer Germany
Primary
Concomitant
Psychotic Disorder Hospitalization 9/10/2010 65 Female 106 lb 9/22/2011 Physician United States
Primary
Secondary
Concomitant
Headache Hospitalization 7/24/2010 76 Female 9/23/2011 Physician Netherlands
Primary
Concomitant
Aortic Elongation Hospitalization 5/1/2011 72 Female 9/20/2011 Physician Spain
Primary
Concomitant
Cellulitis Hospitalization 7/26/2011 54 Female 181 lb 9/26/2011 Physician Netherlands
Primary
Secondary
Concomitant
Encephalitis Viral Other Serious 8/19/2011 68 Male 127 lb 10/5/2011 Physician Japan
Primary
Secondary
Concomitant
Oesophageal Adenocarcinoma Hospitalization 7/1/2011 58 Male 207 lb 10/17/2011 Physician Switzerland
Primary
Secondary
Concomitant
Pancreatic Carcinoma Metastatic Life Threatening 9/15/2011 66 Female 196 lb 10/20/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Headache Hospitalization 7/24/2010 56 Female 10/24/2011 Physician Netherlands
Primary
Concomitant
Oesophagitis Hospitalization 1/1/2011 67 Female 229 lb 11/7/2011 Physician Germany
Primary
Secondary
Concomitant
Headache Hospitalization 7/24/2010 56 Female 11/8/2011 Physician Netherlands
Primary
Concomitant
Pathological Fracture Hospitalization 9/1/2011 77 Female 11/14/2011 Other Health Professional Sweden
Primary
Concomitant
Basal Cell Carcinoma Hospitalization 6/28/2010 61 Female 116 lb 11/11/2011 Physician Japan
Primary
Secondary
Myelodysplastic Syndrome Hospitalization 8/22/2011 65 Male 121 lb 11/11/2011 Physician Japan
Primary
Secondary

Drug Data