Folic Acid combined with Methotrexate Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Decreased Other Serious 6/1/2005 Female 130 lb 1/6/2006 United States
Primary
Concomitant
Spinal Compression Fracture Hospitalization 9/26/2005 Female 1/17/2006 Belgium
Primary
Concomitant
Respiratory Failure Hospitalization 6/30/2005 Female 1/23/2006 Germany
Primary
Concomitant
Peripheral Vascular Disorder Hospitalization 6/15/2005 Male 2/2/2006 United Kingdom
Primary
Concomitant
Muscle Spasms Hospitalization 12/9/2005 Female 176 lb 2/2/2006 Canada
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 6/30/2005 Female 2/3/2006 Germany
Primary
Concomitant
Weight Decreased Hospitalization 4/19/2005 Male 139 lb 2/7/2006 Germany
Primary
Concomitant
Pyrexia Hospitalization 7/1/2004 64 Female 2/8/2006 Germany
Primary
Concomitant
Sepsis Hospitalization 12/9/2004 Male 157 lb 2/9/2006 United Kingdom
Primary
Concomitant
Listeriosis Hospitalization 4/29/2005 Female 110 lb 2/9/2006 United Kingdom
Primary
Concomitant
Impaired Healing Hospitalization 10/17/2005 Female 2/9/2006 United Kingdom
Primary
Concomitant
Hodgkin's Disease Stage Iii Other Serious 11/1/2004 Male 183 lb 2/9/2006 Germany
Primary
Concomitant
Multi-organ Failure Other Serious Female 152 lb 2/9/2006 United Kingdom
Primary
Concomitant
Pain In Extremity Other Serious 9/15/2004 Male 174 lb 2/9/2006 United Kingdom
Primary
Concomitant
Pneumonia Hospitalization Female 2/10/2006 United Kingdom
Primary
Concomitant
Peripheral Vascular Disorder Hospitalization 6/15/2005 Male 2/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
Cough Other Serious 1/1/2005 Female 220 lb 3/2/2006 Other Health Professional United States
Primary
Concomitant
Pulmonary Embolism Hospitalization Male 143 lb 3/7/2006 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Failure Hospitalization 6/30/2005 Female 3/9/2006 Physician Germany
Primary
Concomitant
Abscess Other Serious 3/8/2006 Male 165 lb 3/15/2006 Consumer Canada
Primary
Concomitant
Scleritis Disability 3/31/2005 Female 3/31/2006 Japan
Primary
Concomitant
Pulmonary Embolism Hospitalization 10/14/2005 Female 276 lb 3/31/2006 Consumer United Kingdom
Primary
Concomitant
Respiratory Failure Hospitalization 6/30/2005 Female 4/4/2006 Physician Germany
Primary
Concomitant
Surgery Other Serious 6/15/2005 Male 4/6/2006 Consumer United Kingdom
Primary
Concomitant
Sepsis Hospitalization Female 4/6/2006 Consumer United Kingdom
Primary
Concomitant
Abscess Other Serious 3/8/2006 Male 165 lb 4/17/2006 Consumer Canada
Primary
Concomitant
Basal Cell Carcinoma Other Serious 11/1/2005 Male 170 lb 4/24/2006 Physician United States
Primary
Concomitant
Basal Cell Carcinoma Other Serious 11/1/2005 Male 178 lb 4/24/2006 Physician United States
Primary
Concomitant
Myasthenia Gravis Hospitalization 1/12/2006 Female 4/24/2006 Other Health Professional Italy
Primary
Concomitant
Pulmonary Embolism Hospitalization 10/17/2005 Male 143 lb 5/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 10/14/2005 Female 276 lb 5/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Endodontic Procedure Other Serious 5/4/2006 Female 112 lb 5/11/2006 Consumer Canada
Primary
Concomitant
Sinusitis Other Serious 1/1/2006 Female 146 lb 6/12/2006 Physician United States
Primary
Concomitant
Scleritis Disability 10/21/2004 Female 6/16/2006 Japan
Primary
Concomitant
Surgery Other Serious 6/15/2005 Male 6/16/2006 Consumer United Kingdom
Primary
Concomitant
Uterine Polyp Other Serious 11/17/2005 Female 137 lb 6/19/2006 Physician Italy
Primary
Concomitant
Uterine Polyp Other Serious 11/17/2005 Female 137 lb 6/19/2006 Physician Italy
Primary
Concomitant
Synovial Cyst Hospitalization 2/7/2005 Female 6/21/2006 Japan
Primary
Concomitant
Tuberculin Test Positive Hospitalization 65 Female 6/28/2006 Physician Greece
Primary
Concomitant
Pericarditis Other Serious 2/28/2006 Female 121 lb 6/30/2006 Other Health Professional United Kingdom
Primary
Concomitant
Cervix Disorder Hospitalization 2/16/2006 7/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Convulsion Hospitalization 5/7/2006 Female 215 lb 7/12/2006 Physician United States
Primary
Concomitant
Left Ventricular Failure Hospitalization 2/24/2006 Male 203 lb 7/18/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Other Serious 8/20/2005 Female 117 lb 7/24/2006 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Failure Death 9/10/2005 Female 137 lb 7/24/2006 Physician United Kingdom
Primary
Concomitant
Endodontic Procedure Other Serious 5/4/2006 Female 112 lb 7/28/2006 Consumer Canada
Primary
Concomitant
Cerebrovascular Disorder Death 9/17/2003 Male 368 lb 8/2/2006 United Kingdom
Primary
Concomitant
Spleen Disorder Other Serious 3/1/2006 62 Female 8/2/2006 Physician Spain
Primary
Concomitant
Vestibulitis Other Serious 10/17/2005 Female 8/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Hospitalization 12/29/2005 Female 8/2/2006 Consumer United Kingdom
Primary
Concomitant
Labyrinthitis Hospitalization 7/13/2006 Female 160 lb 8/4/2006 Consumer Canada
Primary
Secondary
Concomitant
Overdose Hospitalization 11/14/2004 Female 207 lb 8/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Other Serious 12/1/2004 Female 175 lb 8/17/2006 Physician United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 7/1/2004 64 Female 8/18/2006 Physician Germany
Primary
Concomitant
Urinary Tract Infection Other Serious 11/15/2003 Female 143 lb 8/24/2006 Other Health Professional United Kingdom
Primary
Concomitant
Diarrhoea Hospitalization 2/18/2006 Female 117 lb 8/25/2006 Germany
Primary
Concomitant
Muscle Necrosis Hospitalization 6/16/2006 Female 132 lb 9/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 7/21/2006 Male 216 lb 9/8/2006 Physician Germany
Primary
Concomitant
Caecitis Hospitalization 2/18/2006 Female 117 lb 9/20/2006 Germany
Primary
Concomitant
Wegener's Granulomatosis Hospitalization 11/3/2005 Female 9/21/2006 Physician Germany
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 8/21/2006 45 Male 9/27/2006 Physician Spain
Primary
Concomitant
Cystitis Pseudomonal Other Serious 74 Female 152 lb 10/10/2006 Other Health Professional United Kingdom
Primary
Concomitant
Dyspnoea Hospitalization 7/4/2006 81 Female 146 lb 10/19/2006 Physician Greece
Primary
Concomitant
Tendon Rupture Other Serious 1/1/2004 Female 10/19/2006 Consumer United States
Primary
Concomitant
Reflux Oesophagitis Hospitalization 7/1/2006 Male 10/19/2006 Other Health Professional Germany
Primary
Concomitant
Urinary Tract Infection Other Serious 1/31/2006 Female 130 lb 10/19/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Tuberculosis Hospitalization 7/13/2006 35 123 lb 10/20/2006 Physician Lithuania
Primary
Concomitant
Septic Shock Life Threatening 12/30/2005 Male 10/20/2006 Physician United States
Primary
Secondary
Concomitant
Wheezing Hospitalization 1/1/2006 58 Male 200 lb 10/12/2006 Physician United States
Primary
Concomitant
Urosepsis Hospitalization 8/26/2006 Female 10/23/2006 Physician United States
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Hospitalization 7/13/2006 35 Male 123 lb 10/25/2006 Physician Lithuania
Primary
Concomitant
Vocal Cord Thickening Other Serious 1/1/2005 Male 230 lb 10/26/2006 Physician United States
Primary
Concomitant
Hypertension Hospitalization 4/12/2006 Female 10/26/2006 Other Health Professional Belgium
Primary
Concomitant
Reflux Oesophagitis Hospitalization 7/1/2006 Male 10/27/2006 Other Health Professional Germany
Primary
Concomitant
Eczema Hospitalization 9/1/2006 Female 121 lb 10/27/2006 Italy
Primary
Concomitant
Subdural Haematoma Hospitalization 3/1/2006 Female 140 lb 10/27/2006 Consumer United States
Primary
Concomitant
Systemic Lupus Erythematosus Rash Other Serious 6/5/2006 Female 132 lb 10/27/2006 Other Health Professional United Kingdom
Primary
Concomitant
Renal Oncocytoma Other Serious 8/1/2006 Male 273 lb 10/27/2006 Physician United States
Primary
Concomitant
Prostate Cancer Other Serious 1/1/2006 Male 10/30/2006 Physician United States
Primary
Concomitant
Lung Neoplasm Malignant Death Female 10/30/2006 Physician United States
Primary
Concomitant
Acute Pulmonary Histoplasmosis Other Serious 12/1/2005 Male 10/30/2006 Physician United States
Primary
Concomitant
Basal Cell Carcinoma Other Serious 3/1/2006 Female 10/30/2006 Physician United States
Primary
Concomitant
Mesenteric Fibrosis Hospitalization 2/1/2006 Male 10/30/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 4/1/2006 Female 10/30/2006 Physician United States
Primary
Concomitant
Pulmonary Oedema Life Threatening 4/6/2006 Female 131 lb 10/30/2006 Physician United States
Primary
Concomitant
Mesenteric Artery Stenosis Hospitalization 3/1/2006 Female 10/30/2006 Physician United States
Primary
Concomitant
Spinal Compression Fracture Other Serious 10/23/2006 Female 298 lb 12/7/2006 Consumer Canada
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 3/11/2006 Female 12/21/2006 Physician United States
Primary
Concomitant
Spinal Compression Fracture Other Serious 10/23/2006 Female 298 lb 12/29/2006 Consumer Canada
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 7/1/2006 Male 1/4/2007 Physician Germany
Primary
Secondary
Concomitant
Spinal Compression Fracture Other Serious 10/23/2006 Female 298 lb 1/5/2007 Consumer Canada
Primary
Concomitant
Pulmonary Mass Other Serious 12/1/2006 Female 1/15/2007 Consumer United States
Primary
Concomitant
Umbilical Hernia Hospitalization 8/15/2006 Female 187 lb 1/19/2007 Other Health Professional United Kingdom
Primary
Concomitant
Rheumatoid Lung Other Serious Female 152 lb 1/25/2007 Physician United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Other Serious Female 215 lb 1/25/2007 Consumer Canada
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 1/1/2006 Male 190 lb 1/27/2007 Consumer Canada
Primary
Concomitant
Wegener's Granulomatosis Other Serious 2/24/2005 Female 2/6/2007 Physician Germany
Primary
Secondary
Concomitant
Uterine Leiomyoma Other Serious 12/16/2006 Female 169 lb 2/6/2007 Consumer Canada
Primary
Concomitant
Syncope Vasovagal Other Serious 8/19/2006 Male 174 lb 2/15/2007 Other Health Professional United Kingdom
Primary
Concomitant
Skin Ulcer Hospitalization 11/28/2006 70 Female 2/20/2007 Other Health Professional Poland
Primary
Secondary
Concomitant
Uterine Leiomyoma Other Serious 12/1/2006 Female 169 lb 2/22/2007 Consumer Canada
Primary
Concomitant
Pulmonary Tuberculosis Other Serious 1/2/2007 68 Male 3/5/2007 Other Health Professional Portugal
Primary
Secondary
Concomitant
Swelling Hospitalization 11/14/2006 Female 180 lb 3/5/2007 Consumer Canada
Primary
Concomitant
Hepatic Steatosis Other Serious 1/1/2006 Male 190 lb 3/13/2007 Consumer Canada
Primary
Secondary
Concomitant
Sensation Of Heaviness Hospitalization 3/1/2007 51 Male 3/16/2007 Physician United States
Primary
Secondary
Concomitant
Pain Other Serious 1/16/2007 Male 3/23/2007 Physician Belgium
Primary
Secondary
Concomitant
Papilloma Viral Infection Other Serious 9/1/2006 Female 3/30/2007 Physician Belgium
Primary
Concomitant
Wrist Surgery Other Serious 2/27/2007 Female 105 lb 4/6/2007 Consumer United States
Primary
Concomitant
Cerebral Haemorrhage Hospitalization 1/4/2006 Male 4/9/2007 Physician Belgium
Primary
Concomitant
Intervertebral Disc Protrusion Hospitalization 7/3/2006 Female 4/11/2007 Physician Belgium
Primary
Concomitant
Uterine Polyp Other Serious 11/17/2005 Female 137 lb 4/12/2007 Physician Italy
Primary
Concomitant
Pyrexia Hospitalization 1/12/2007 81 Female 4/12/2007 Physician Austria
Primary
Concomitant
Pyrexia Other Serious 4/8/2007 59 Female 4/16/2007 Other Health Professional Mexico
Primary
Secondary
Concomitant
Cholecystitis Hospitalization 2/5/2007 54 Female 4/23/2007 Consumer Poland
Primary
Concomitant
Sepsis Hospitalization 4/20/2007 40 Female 4/26/2007 Consumer Argentina
Primary
Secondary
Concomitant
Escherichia Urinary Tract Infection Hospitalization 4/20/2007 40 Female 4/30/2007 Consumer Argentina
Primary
Secondary
Concomitant
Urine Analysis Abnormal Hospitalization 3/1/2007 Female 5/1/2007 Physician Belgium
Primary
Concomitant
Pain Hospitalization 1/21/2007 Female 137 lb 5/4/2007 Consumer Canada
Primary
Concomitant
Escherichia Urinary Tract Infection Hospitalization 4/20/2007 40 Female 5/7/2007 Consumer Argentina
Primary
Secondary
Concomitant
Joint Destruction Other Serious Female 126 lb 5/11/2007 Consumer Canada
Primary
Concomitant
Pain Other Serious 1/16/2007 Male 5/11/2007 Physician Belgium
Primary
Secondary
Concomitant
Surgery Hospitalization 10/4/2006 Female 5/15/2007 Physician Belgium
Primary
Concomitant
Urine Analysis Abnormal Hospitalization 3/1/2007 Female 5/15/2007 Physician Belgium
Primary
Concomitant
Uterine Leiomyoma Other Serious 12/1/2006 Female 169 lb 5/16/2007 Consumer Canada
Primary
Concomitant
Osteoarthritis Other Serious 2/27/2007 Female 105 lb 5/17/2007 Physician Canada
Primary
Concomitant
Joint Dislocation Hospitalization 5/22/2006 Female 5/25/2007 Physician Belgium
Primary
Concomitant
Vitamin D Decreased Required Intervention 5/29/2006 71 Female 141 lb 2/7/2007 Physician United States
Primary
Concomitant
Pneumonia Death 79 Male 5/22/2007 United Kingdom
Primary
Concomitant
Necrosis Death 6/18/2006 33 Female 5/31/2007 Consumer Brazil
Primary
Concomitant
Pneumomediastinum Hospitalization 2/24/2007 Female 5/31/2007 Physician Belgium
Primary
Concomitant
Leiomyosarcoma Other Serious 11/10/2004 Female 157 lb 5/31/2007 Other Health Professional United Kingdom
Primary
Concomitant
Skin Reaction Other Serious 4/5/2007 Female 5/31/2007 Other Health Professional Ireland
Primary
Concomitant
Bronchial Carcinoma Other Serious 11/25/2006 Female 161 lb 6/1/2007 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Infarction Other Serious 78 Female 181 lb 6/1/2007 Other Health Professional United Kingdom
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 5/15/2006 69 Female 106 lb 6/1/2007 Other Health Professional United Kingdom
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 12/16/2006 Female 119 lb 6/1/2007 Other Health Professional United Kingdom
Primary
Concomitant
Cardiac Tamponade Other Serious 11/3/2006 Male 192 lb 6/1/2007 Other Health Professional United Kingdom
Primary
Concomitant
Joint Destruction Other Serious 68 Male 6/1/2007 Consumer Brazil
Primary
Concomitant
Neoplasm Malignant Other Serious 7/5/2004 Male 220 lb 6/1/2007 Other Health Professional United Kingdom
Primary
Concomitant
Hyperglycaemia Other Serious 5/3/2007 46 Female 6/1/2007 Consumer United States
Primary
Secondary
Concomitant
Varices Oesophageal Other Serious 12/15/2006 Female 212 lb 6/1/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 1/1/2005 Male 154 lb 6/1/2007 Other Health Professional Canada
Primary
Concomitant
Syncope Hospitalization 4/12/2006 Female 143 lb 6/1/2007 Physician United Kingdom
Primary
Concomitant
Skin Lesion Other Serious 4/1/2007 Female 6/1/2007 Physician United States
Primary
Concomitant
Non-small Cell Lung Cancer Other Serious 12/1/2006 Male 187 lb 6/1/2007 Physician Denmark
Primary
Secondary
Concomitant
Abortion Spontaneous Other Serious 11/8/2005 Female 108 lb 6/1/2007 Other Health Professional United Kingdom
Primary
Concomitant
Toe Operation Other Serious 9/1/2006 Male 163 lb 6/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Neoplasm Other Serious 10/13/2006 Male 240 lb 6/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Thrombophlebitis Hospitalization 4/9/2007 80 Female 6/4/2007 Other Health Professional Argentina
Primary
Secondary
Concomitant
Visceral Leishmaniasis Life Threatening 1/12/2006 Female 154 lb 6/5/2007 Netherlands
Primary
Concomitant

Drug Data