Cytarabine combined with Methotrexate Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Complex Partial Seizures Other Serious 20 Male 5/12/2006 Physician United States
Primary
Concomitant
Hypoaesthesia Other Serious Female 5/12/2006 Physician United States
Primary
Concomitant
Weight Decreased Life Threatening 63 Female 174 lb 10/25/2006 Other Health Professional Germany
Primary
Secondary
Vasculitis Cerebral Hospitalization 4/23/2007 53 Female 5/22/2007 Physician France
Primary
Concomitant
Vomiting Hospitalization 5/14/2007 59 Female 146 lb 6/2/2007 Physician France
Primary
Secondary
Spinal Cord Disorder Other Serious 28 Female 6/6/2007 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Spinal Cord Disorder Other Serious 60 Female 6/6/2007 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Depression Other Serious 6/7/2007
Primary
Secondary
Stomatitis Other Serious 6/7/2007
Primary
Secondary
Embolism Other Serious 6/7/2007
Primary
Secondary
Hepatotoxicity Other Serious 6/7/2007
Primary
Secondary
Urogenital Disorder Other Serious 6/7/2007
Primary
Secondary
Hepatotoxicity Other Serious 6/7/2007
Primary
Secondary
Drug Effect Decreased Other Serious 6/7/2007
Primary
Secondary
Drug Effect Decreased Other Serious 6/7/2007
Primary
Secondary
Leukopenia Death 6/7/2007
Primary
Secondary
Adverse Event Death 6/7/2007
Primary
Secondary
Leukoencephalopathy Death 6/7/2007
Primary
Secondary
Drug Effect Decreased Other Serious 6/7/2007
Primary
Secondary
Drug Effect Decreased Other Serious 6/7/2007
Primary
Secondary
Skin Toxicity Other Serious 6/7/2007
Primary
Secondary
Myeloid Leukaemia Other Serious 1 Male 7/31/2007 Other Health Professional United Kingdom
Primary
Secondary
Myeloid Leukaemia Other Serious 3 Female 8/1/2007 Other Health Professional United Kingdom
Primary
Secondary
Maculopathy Required Intervention 65 Unknown 7/31/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Disturbance Required Intervention 66 Unknown 7/31/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Required Intervention 66 Unknown 7/31/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Maculopathy Required Intervention 73 Unknown 7/31/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Maculopathy Required Intervention 34 Unknown 7/31/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 12/5/2007 25 Male 7/10/2008 Physician Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 3 Male 7/25/2008 Consumer Canada
Primary
Concomitant
Spinal Compression Fracture Hospitalization 11/1/1998 43 Male 8/12/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Stem Cell Transplant Death 39 Female 8/9/2008 United States
Primary
Secondary
Subarachnoid Haemorrhage Life Threatening 0 Female 8/11/2008 United Kingdom
Primary
Secondary
Sepsis Hospitalization 10/9/2007 Male 129 lb 8/14/2008 United States
Primary
Secondary
Concomitant
Fungal Sepsis Death 8/19/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Osteoporosis Other Serious 11/1/1998 43 Male 8/20/2008 United Kingdom
Primary
Secondary
Concomitant
Spinal Compression Fracture Hospitalization 11/1/1998 43 Male 8/22/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Serotonin Syndrome Life Threatening 8/26/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 44 Female 10/7/2008 Japan
Primary
Secondary
Myelopathy Other Serious 15 Male 1/29/2009 Other Health Professional United States
Primary
Secondary
Unresponsive To Stimuli Other Serious 14 Male 1/29/2009 Other Health Professional United States
Primary
Secondary
Osteonecrosis Hospitalization 4/1/2005 2/24/2009 Physician Denmark
Primary
Secondary
Osteonecrosis Hospitalization 4/1/2005 3/20/2009 Physician Denmark
Primary
Secondary
Malaise Other Serious 12/13/2008 3/31/2009 Other Health Professional France
Primary
Secondary
Concomitant
Acute Promyelocytic Leukaemia Other Serious 53 Male 4/23/2009 Other Health Professional France
Primary
Secondary
Acute Promyelocytic Leukaemia Other Serious 51 Male 4/23/2009 Other Health Professional France
Primary
Secondary
Acute Promyelocytic Leukaemia Other Serious 48 Female 4/23/2009 Other Health Professional France
Primary
Secondary
Acute Promyelocytic Leukaemia Other Serious 20 Male 4/23/2009 Other Health Professional France
Primary
Secondary
Acute Promyelocytic Leukaemia Other Serious 36 Male 4/23/2009 Other Health Professional France
Primary
Secondary
Axonal Neuropathy Other Serious 1/1/2009 85 5/13/2009 Other Health Professional France
Primary
Secondary
Axonal Neuropathy Other Serious 1/1/2009 Female 5/14/2009 Other Health Professional France
Primary
Secondary
Syncope Hospitalization 1/23/2009 14 Female 5/28/2009 Netherlands
Primary
Secondary
Concomitant
Drug Toxicity Hospitalization 6/8/2009 Male 71 lb 6/12/2009 United States
Primary
Secondary
Screaming Hospitalization 6/22/2009 Male 50 lb 6/24/2009 Physician United States
Primary
Secondary
Sinus Tachycardia Hospitalization 8/10/2009 Male 79 lb 8/19/2009 United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 8/14/2009 Male 155 lb 8/17/2009 United States
Primary
Secondary
Transplant Other Serious 13 Male 8/21/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 8/24/2009 51 Male 153 lb 8/25/2009 Other Health Professional United States
Primary
Secondary
Sepsis Other Serious 1/30/2009 40 Male 110 lb 8/27/2009 Japan
Primary
Concomitant
Somnolence Other Serious 1/1/2009 13 Male 8/27/2009 Consumer France
Primary
Concomitant
Syncope Hospitalization 1/23/2009 Female 10/1/2009 Physician Netherlands
Primary
Secondary
Concomitant
Syncope Hospitalization 1/26/2009 14 Female 10/6/2009 Physician Netherlands
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Other Serious 9 Male 11/30/2009 Physician Japan
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Other Serious 9 Male 12/7/2009 Physician Japan
Primary
Concomitant
Lymphopenia Other Serious 4/29/2009 4 Male 12/17/2009 Physician United States
Primary
Secondary
Neuropathy Peripheral Other Serious 14 Male 12/29/2009 Other Health Professional United States
Primary
Secondary
Lymphopenia Other Serious 4/29/2009 4 Male 12/30/2009 Physician United States
Primary
Secondary
Lymphopenia Other Serious 4/29/2009 4 Male 12/30/2009 Physician United States
Primary
Secondary
Sensorimotor Disorder Hospitalization 1/1/2009 62 Female 8/3/2010 Other Health Professional France
Primary
Secondary
Concomitant
Wernicke-korsakoff Syndrome Other Serious 62 Female 8/13/2010 Other Health Professional United Kingdom
Primary
Secondary
Wernicke-korsakoff Syndrome Other Serious 62 Female 8/23/2010 Other Health Professional United Kingdom
Primary
Secondary
Wernicke-korsakoff Syndrome Other Serious 62 Female 8/30/2010 Other Health Professional United Kingdom
Primary
Secondary
Wernicke-korsakoff Syndrome Other Serious 62 Female 10/6/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Headache Hospitalization 10/15/2010 19 Male 155 lb 10/18/2010 United States
Primary
Secondary
Cognitive Disorder Other Serious 60 Female 12/22/2010 Physician Japan
Primary
Secondary
T-cell Lymphoma Refractory Other Serious Male 12/31/2010 Other Health Professional Japan
Primary
Secondary
Polyomavirus-associated Nephropathy Other Serious 55 Male 1/5/2011 Other Health Professional Japan
Primary
Secondary
Hepatocellular Injury Hospitalization 7/28/2010 52 Male 2/14/2011 Other Health Professional France
Primary
Secondary
Concomitant
Bacterial Sepsis Hospitalization 7/28/2010 52 Male 2/21/2011 Other Health Professional France
Primary
Secondary
Concomitant
Bacterial Sepsis Hospitalization 1/1/2010 52 Male 2/22/2011 Other Health Professional France
Primary
Secondary
Concomitant
Cognitive Disorder Other Serious 60 Female 3/1/2011 Physician Japan
Primary
Secondary
Hypophosphataemia Life Threatening 1/1/2010 52 Male 3/7/2011 Other Health Professional France
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 55 Male 4/14/2011 Other Health Professional United Kingdom
Primary
Secondary
Septic Shock Death 54 Male 4/18/2011 Other Health Professional United Kingdom
Primary
Secondary
Burkitt's Lymphoma Death 55 Male 4/27/2011 Other Health Professional United Kingdom
Primary
Secondary
Bone Marrow Failure Death 57 Female 4/27/2011 Physician Japan
Primary
Secondary
Toxicity To Various Agents Death 55 Male 5/5/2011 Other Health Professional United Kingdom
Primary
Secondary
Bacterial Sepsis Life Threatening 1/1/2010 52 Male 5/9/2011 Other Health Professional France
Primary
Secondary
Concomitant
Septic Shock Other Serious 54 Male 5/13/2011 Other Health Professional United Kingdom
Primary
Secondary
Febrile Neutropenia Other Serious 54 Male 5/19/2011 Other Health Professional United Kingdom
Primary
Secondary
Lymphopenia Hospitalization 4/29/2009 4 Male 5/20/2011 Physician United States
Primary
Secondary
Alanine Aminotransferase Increased Hospitalization 4/29/2009 4 Male 5/20/2011 Physician United States
Primary
Secondary
Toxicity To Various Agents Other Serious 55 Male 5/23/2011 Consumer United Kingdom
Primary
Secondary
Cerebral Venous Thrombosis Hospitalization 11/5/2010 42 Male 5/24/2011 Other Health Professional France
Primary
Secondary
Concomitant
Febrile Neutropenia Death 54 Male 5/25/2011 Other Health Professional United Kingdom
Primary
Secondary
Febrile Neutropenia Life Threatening 54 Male 5/26/2011 Other Health Professional United Kingdom
Primary
Secondary
Burkitt's Lymphoma Other Serious 55 Male 5/27/2011 Consumer United Kingdom
Primary
Secondary
Pneumonia Hospitalization 1/11/2011 65 Male 5/31/2011 Physician Japan
Primary
Secondary
Cerebral Venous Thrombosis Hospitalization 11/5/2010 42 Male 6/1/2011 Other Health Professional France
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/11/2011 65 Male 6/3/2011 Physician Japan
Primary
Secondary
Cerebral Haemorrhage Other Serious 12 Female 104 lb 6/6/2011 Physician Japan
Primary
Secondary
Anaemia Other Serious 4/27/2009 68 Female 6/17/2011 Physician Japan
Primary
Secondary
Pulmonary Veno-occlusive Disease Other Serious 5 Male 7/18/2011 Other Health Professional Japan
Primary
Secondary
Interstitial Lung Disease Hospitalization 1/11/2011 66 Male 8/2/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 1/11/2011 66 Male 8/9/2011 Physician Japan
Primary
Secondary
Concomitant
Neutropenia Other Serious 1 Female 9/1/2011 Physician Japan
Primary
Secondary
Septic Shock Other Serious 1 Female 9/7/2011 Physician Japan
Primary
Secondary
Encephalitis Viral Hospitalization 8/19/2011 68 Male 127 lb 9/7/2011 Physician Japan
Primary
Secondary
Concomitant
Septic Shock Death 1 Female 9/9/2011 Physician Japan
Primary
Secondary
Septic Shock Hospitalization 9/12/2011 55 Female 95 lb 9/23/2011 Physician Japan
Primary
Secondary
Concomitant
Enterocolitis Hospitalization 8/8/2011 70 Male 124 lb 9/26/2011 Physician Japan
Primary
Secondary
Concomitant
Device Related Sepsis Death 9/12/2011 55 Female 95 lb 9/27/2011 Physician Japan
Primary
Secondary
Concomitant
Septic Shock Hospitalization 9/12/2011 55 Female 95 lb 10/3/2011 Physician Japan
Primary
Secondary
Concomitant
Encephalitis Viral Other Serious 8/19/2011 68 Male 127 lb 10/5/2011 Physician Japan
Primary
Secondary
Concomitant
Peripheral Sensory Neuropathy Hospitalization 9/1/2010 53 Male 10/10/2011 Physician France
Primary
Secondary
Concomitant
Cholecystitis Hospitalization 9/26/2011 60 Female 10/14/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Posterior Reversible Encephalopathy Syndrome Hospitalization 10/8/2011 9 Male 57 lb 10/21/2011 Physician Czech Republic
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 1/11/2011 66 Male 10/24/2011 Physician Japan
Primary
Secondary
Concomitant
Colitis Ischaemic Hospitalization 10/14/2011 74 Male 10/26/2011 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 9/1/2010 53 Male 10/11/2011 Physician France
Primary
Secondary
Concomitant
Colitis Ischaemic Hospitalization 10/14/2011 74 Male 11/9/2011 Physician Japan
Primary
Secondary
Concomitant
Enterocolitis Infectious Hospitalization 6/17/2011 22 Female 11/10/2011 Physician United States
Primary
Secondary
Myelodysplastic Syndrome Hospitalization 8/22/2011 65 Male 121 lb 11/11/2011 Physician Japan
Primary
Secondary
Ovarian Failure Other Serious 20 Female 12/12/2011 Physician Japan
Primary
Secondary
Breath Sounds Abnormal Hospitalization 13 Female 12/14/2011 Other Health Professional Turkey
Primary
Secondary
Leukoencephalopathy Other Serious 10/26/2011 9 Female 12/14/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 39 Female 12/29/2011 Physician Japan
Primary
Secondary
Concomitant
Septic Shock Life Threatening 7/6/2011 62 Male 1/11/2012 Other Health Professional France
Primary
Secondary
Concomitant
Leukoencephalopathy Hospitalization 1/1/2011 9 Female 1/27/2012 Pharmacist Japan
Primary
Secondary
Concomitant
Thirst Other Serious 8/11/2011 68 Male 127 lb 3/9/2012 Physician Japan
Primary
Secondary
Concomitant
Candidiasis Other Serious 13 Female 4/6/2012 Physician Greece
Primary
Secondary
Candidiasis Other Serious 4 Female 4/6/2012 Physician Greece
Primary
Secondary
Blood Creatinine Increased Death 3/22/2012 59 Male 4/10/2012 Pharmacist Japan
Primary
Concomitant
Cholecystitis Hospitalization 4/22/2011 60 Female 4/10/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Candidiasis Other Serious 4 Female 4/12/2012 Physician Greece
Primary
Secondary
Candidiasis Other Serious 13 Female 4/12/2012 Physician Greece
Primary
Secondary
Candidiasis Other Serious 2 Male 4/12/2012 Physician Greece
Primary
Secondary
Disease Progression Other Serious 3/22/2012 59 Male 4/16/2012 Pharmacist Japan
Primary
Concomitant
Ileus Paralytic Hospitalization 4/22/2011 60 Female 4/19/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Cholecystitis Hospitalization 4/22/2011 60 Female 4/30/2012 Other Health Professional Japan
Primary
Secondary
Death Death 61 Male 5/2/2012 Physician Greece
Primary
Secondary
Sepsis Hospitalization 7/18/2011 8 Male 5/4/2012 Physician United States
Primary
Secondary
Leukoencephalopathy Other Serious 21 Female 5/10/2012 Other Health Professional United States
Primary
Secondary
Death Death 61 Male 5/18/2012 Physician Greece
Primary
Secondary
Febrile Neutropenia Hospitalization 5/11/2012 38 Female 6/25/2012 Physician United States
Primary
Secondary
Myeloid Leukaemia Other Serious 6/26/2012 Physician United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 1/11/2011 66 Male 7/19/2012 Physician Japan
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 7/10/2012 9 Male 61 lb 7/24/2012 United States
Primary
Secondary
Subdural Haematoma Hospitalization 5/22/2012 51 Female 8/2/2012 Physician United States
Primary
Secondary
Ischaemic Stroke Hospitalization 6/4/2012 63 Female 7/27/2012 Physician France
Primary
Secondary
Concomitant

Drug Data