Irinotecan Hydrochloride



Indications and Reactions:

Role Indications Reactions
Primary
Colorectal Cancer Metastatic 16.9%
Colon Cancer 15.4%
Colorectal Cancer 8.9%
Colon Cancer Metastatic 6.6%
Glioblastoma Multiforme 6.4%
Rectal Cancer 6.2%
Metastatic Colorectal Cancer 5.8%
Pancreatic Carcinoma 5.5%
Gastrointestinal Carcinoma 4.5%
Product Used For Unknown Indication 4.3%
Chemotherapy 3.6%
Neuroblastoma 2.3%
Pancreatic Carcinoma Metastatic 2.3%
Breast Cancer Metastatic 2.1%
Adenocarcinoma 1.9%
Adenocarcinoma Of Colon 1.7%
Rectal Cancer Stage Iv 1.7%
Lung Adenocarcinoma Stage Iii 1.5%
Gastric Cancer 1.3%
Prophylaxis Of Nausea And Vomiting 1.1%
Vomiting 12.8%
Neuropathy Peripheral 9.6%
Diarrhoea 6.4%
Febrile Neutropenia 5.3%
Pulmonary Embolism 5.3%
Thrombocytopenia 5.3%
Toxicity To Various Agents 5.3%
Abdominal Pain 4.3%
Acute Myeloid Leukaemia 4.3%
Muscular Weakness 4.3%
Neutropenia 4.3%
Paraesthesia 4.3%
Respiratory Failure 4.3%
Speech Disorder 4.3%
Tachycardia 4.3%
Chronic Myeloid Leukaemia 3.2%
Erythema 3.2%
Hypokalaemia 3.2%
Pulmonary Fibrosis 3.2%
Pyrexia 3.2%
Secondary
Colorectal Cancer 27.9%
Colorectal Cancer Metastatic 14.8%
Colon Cancer 7.9%
Colon Cancer Metastatic 7.2%
Drug Use For Unknown Indication 6.5%
Product Used For Unknown Indication 4.8%
Prophylaxis 4.3%
Rectal Cancer Metastatic 3.7%
Rectal Cancer 3.1%
Pancreatic Carcinoma 3.0%
Large Intestine Carcinoma 2.4%
Glioblastoma Multiforme 2.4%
Glioblastoma 2.2%
Rectal Cancer Recurrent 1.8%
Gastric Cancer 1.7%
Hypertension 1.6%
Prophylaxis Of Nausea And Vomiting 1.4%
Metastatic Colorectal Cancer 1.1%
Neoplasm 1.1%
Colon Cancer Recurrent 1.0%
Vomiting 12.3%
Interstitial Lung Disease 9.5%
Stomatitis 9.0%
Neutropenia 7.4%
White Blood Cell Count Decreased 6.9%
Diarrhoea 5.6%
Pyrexia 5.6%
Thrombocytopenia 4.6%
Pulmonary Embolism 4.4%
Febrile Neutropenia 4.1%
Paronychia 3.8%
Sepsis 3.6%
General Physical Health Deterioration 3.1%
Intestinal Obstruction 3.1%
Malaise 3.1%
Urinary Tract Infection 3.1%
Weight Decreased 3.1%
Blood Creatinine Increased 2.8%
Disease Progression 2.6%
Dermatitis Acneiform 2.3%
Concomitant
Colorectal Cancer 26.1%
Colon Cancer Metastatic 12.2%
Colon Cancer 9.7%
Rectal Cancer Metastatic 8.8%
Drug Use For Unknown Indication 8.1%
Prophylaxis 7.8%
Rectal Cancer 5.3%
Colorectal Cancer Metastatic 4.4%
Colon Cancer Recurrent 2.6%
Rectal Cancer Recurrent 2.4%
Prophylaxis Of Nausea And Vomiting 1.9%
Large Intestine Carcinoma 1.6%
Chemotherapy 1.4%
Pancreatic Neuroendocrine Tumour 1.4%
Hypertension 1.3%
Product Used For Unknown Indication 1.3%
Glioblastoma Multiforme 1.2%
Premedication 1.2%
Testicular Neoplasm 0.8%
Diabetes Mellitus 0.6%
Dermatitis Acneiform 10.6%
Interstitial Lung Disease 9.7%
Vomiting 8.4%
Stomatitis 7.0%
Hypomagnesaemia 6.2%
Pulmonary Embolism 5.3%
Pyrexia 4.8%
Rash 4.8%
Diarrhoea 4.4%
Disease Progression 4.4%
Death 4.0%
Peritonitis 4.0%
Renal Failure Acute 4.0%
White Blood Cell Count Decreased 4.0%
Colorectal Cancer 3.5%
Neuropathy Peripheral 3.5%
Paronychia 3.1%
Weight Decreased 3.1%
Necrotising Fasciitis 2.6%
Pneumonia 2.6%
Interacting
Epilepsy 40.0%
Antifungal Prophylaxis 20.0%
Chemotherapy 20.0%
Uterine Cancer 20.0%
Hepatic Function Abnormal 50.0%
Uterine Cancer 50.0%