Irinotecan Hydrochloride combined with Panitumumab

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Colitis Hospitalization 8/31/2008 Male 170 lb 10/8/2008 Physician United States
Primary
Concomitant
Interstitial Lung Disease Other Serious 1/10/2007 Male 10/8/2008 Physician Australia
Primary
Concomitant
Hypersensitivity Other Serious 6/16/2008 Female 183 lb 10/20/2008 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Thrombosis Hospitalization 10/3/2008 Male 10/20/2008 Physician Sweden
Primary
Secondary
Concomitant
Laryngospasm Life Threatening 10/8/2008 Female 10/20/2008 Physician Austria
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/28/2008 Male 10/20/2008 Physician United Kingdom
Primary
Secondary
Restrictive Pulmonary Disease Other Serious 1/10/2007 Male 10/22/2008 Physician Australia
Primary
Concomitant
Weight Decreased Hospitalization 7/1/2008 Female 10/27/2008 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Thrombosis Hospitalization 10/3/2008 Male 10/29/2008 Physician Sweden
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/28/2008 Male 201 lb 11/3/2008 Physician United Kingdom
Primary
Secondary
Neutropenia Other Serious 6/1/2007 Male 11/6/2008 Physician United States
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 4/11/2007 Male 144 lb 11/7/2008 Physician United States
Primary
Secondary
Concomitant
Pulmonary Thrombosis Hospitalization 10/3/2008 Male 11/10/2008 Physician Sweden
Primary
Secondary
Concomitant
Hypersensitivity Other Serious 6/16/2008 Female 183 lb 11/18/2008 Physician Germany
Primary
Secondary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 9/26/2008 Female 11/18/2008 Physician United States
Primary
Concomitant
Neutropenia Hospitalization 3/12/2007 Male 153 lb 11/18/2008 Physician United States
Primary
Secondary
Concomitant
Perinephric Collection Hospitalization 9/25/2007 Male 11/19/2008 Physician Australia
Primary
Concomitant
Neutropenia Hospitalization 3/12/2007 Male 153 lb 11/26/2008 Physician United States
Primary
Secondary
Concomitant
Pulmonary Thrombosis Hospitalization 10/4/2008 Male 11/26/2008 Physician Sweden
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/18/2008 Male 11/26/2008 Physician Austria
Primary
Concomitant
Pulmonary Embolism Other Serious 7/9/2008 Female 12/5/2008 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 7/1/2008 Female 12/5/2008 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 9/14/2008 Female 12/5/2008 Physician Germany
Primary
Concomitant
Laryngospasm Life Threatening 10/8/2008 Female 12/5/2008 Physician Austria
Primary
Secondary
Concomitant
Generalised Oedema Hospitalization 10/25/2007 Male 12/9/2008 Physician Italy
Primary
Secondary
Deep Vein Thrombosis Other Serious 5/15/2008 Male 243 lb 12/11/2008 Physician Germany
Primary
Concomitant
Pulmonary Thrombosis Hospitalization 10/4/2008 Male 12/15/2008 Physician Sweden
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/6/2008 Male 12/15/2008 Physician Germany
Primary
Secondary
Diarrhoea Hospitalization 1/15/2008 Female 12/17/2008 Physician United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 12/3/2008 Male 126 lb 12/17/2008 Physician United Kingdom
Primary
Secondary
Malignant Neoplasm Progression Hospitalization 10/25/2007 Male 12/22/2008 Physician Italy
Primary
Concomitant
Myalgia Hospitalization 3/26/2010 72 Female 4/7/2010 Physician Italy
Primary
Concomitant
Renal Failure Acute Hospitalization 3/19/2010 71 Male 198 lb 4/7/2010 Physician United Kingdom
Primary
Secondary
Neutropenia Hospitalization 4/15/2010 56 Male 168 lb 4/21/2010 Physician United Kingdom
Primary
Secondary
Pulmonary Embolism Hospitalization 10/26/2006 47 Female 4/27/2010 Physician United Kingdom
Primary
Concomitant
Neutropenia Hospitalization 4/1/2010 59 Male 231 lb 5/3/2010 Physician United States
Primary
Secondary
Nausea Hospitalization 4/26/2010 77 Male 143 lb 5/6/2010 Physician United Kingdom
Primary
Secondary
Stomatitis Life Threatening 7/6/2010 10/21/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Pneumonia Death 8/4/2010 10/22/2010 Physician Japan
Primary
Concomitant
Colorectal Cancer Death 9/24/2010 10/26/2010 Other Health Professional Japan
Primary
Concomitant
Rash Hospitalization 8/13/2010 10/27/2010 Other Health Professional Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 8/24/2010 10/27/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Necrotising Fasciitis Disability 9/21/2010 60 Male 126 lb 10/27/2010 Physician Japan
Primary
Concomitant
Sepsis Other Serious 10/16/2010 60 Male 10/28/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/12/2010 63 Male 126 lb 10/29/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/12/2010 10/29/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 7/23/2010 10/29/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Hypomagnesaemia Other Serious 7/13/2010 10/29/2010 Other Health Professional Japan
Primary
Concomitant
Sepsis Other Serious 10/16/2010 10/29/2010 Other Health Professional Japan
Primary
Concomitant
Sepsis Other Serious 10/16/2010 60 Male 10/29/2010 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 8/24/2010 11/2/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Hepatic Encephalopathy Death 6/25/2010 11/2/2010 Other Health Professional Japan
Primary
Concomitant
Dermatitis Acneiform Death 7/13/2010 11/5/2010 Other Health Professional Japan
Primary
Concomitant
Stomatitis Death 6/25/2010 11/8/2010 Other Health Professional Japan
Primary
Concomitant
Neutropenia Hospitalization 10/25/2010 11/8/2010 Japan
Primary
Secondary
Dermatitis Acneiform Other Serious 7/13/2010 11/9/2010 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 9/10/2010 11/10/2010 Other Health Professional Japan
Primary
Concomitant
Stomatitis Disability 10/19/2010 11/11/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Ventricular Arrhythmia Other Serious 10/20/2010 11/12/2010 Other Health Professional Japan
Primary
Concomitant
Rash Hospitalization 8/13/2010 11/19/2010 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 7/22/2010 11/19/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 11/2/2010 11/24/2010 Physician Japan
Primary
Secondary
Weight Decreased Disability 9/21/2010 11/24/2010 Physician Japan
Primary
Concomitant
Weight Decreased Disability 9/21/2010 60 Male 126 lb 11/25/2010 Physician Japan
Primary
Concomitant
Dermatitis Acneiform Hospitalization 9/9/2010 11/26/2010 Physician Japan
Primary
Secondary
Concomitant
Gastric Ulcer Haemorrhage Hospitalization 9/25/2010 11/30/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 7/22/2010 12/3/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 7/23/2010 12/6/2010 Physician Japan
Primary
Secondary
Concomitant
Paronychia Other Serious 7/28/2010 66 Female 88 lb 12/6/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 9/15/2010 12/7/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/12/2010 12/8/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 9/3/2010 12/9/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Hypomagnesaemia Life Threatening 12/1/2010 12/9/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/5/2010 12/10/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/16/2010 12/10/2010 Other Health Professional Japan
Primary
Concomitant
Dermatitis Acneiform Other Serious 7/13/2010 12/10/2010 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 7/22/2010 12/10/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 9/30/2010 12/15/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Peritonitis Other Serious 8/25/2010 12/17/2010 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Other Serious 2/1/2009 12/20/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/14/2010 12/21/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Nausea Other Serious 9/7/2010 12/22/2010 Other Health Professional Japan
Primary
Concomitant
Rash Hospitalization 10/18/2010 12/22/2010 Other Health Professional Japan
Primary
Concomitant
Paronychia Other Serious 7/28/2010 12/23/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Paronychia Hospitalization 9/28/2010 12/24/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 9/15/2010 12/28/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Stomatitis Life Threatening 7/6/2010 12/28/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 7/22/2010 12/29/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 10/17/2010 12/30/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Hypomagnesaemia Life Threatening 11/12/2010 12/30/2010 Other Health Professional Japan
Primary
Concomitant
Pyrexia Other Serious 9/9/2010 12/30/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Paronychia Other Serious 7/28/2010 12/30/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Pruritus Hospitalization 10/8/2010 1/5/2011 Physician Japan
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 10/1/2010 1/7/2011 Other Health Professional Japan
Primary
Concomitant
Dermatitis Acneiform Other Serious 9/18/2010 1/7/2011 Physician Japan
Primary
Concomitant
Pneumonia Aspiration Life Threatening 9/15/2010 1/10/2011 Physician Japan
Primary
Secondary
Concomitant
Hypomagnesaemia Hospitalization 7/2/2010 1/10/2011 Physician Japan
Primary
Concomitant
Paronychia Disability 10/19/2010 1/10/2011 Physician Japan
Primary
Secondary
Concomitant
Hypocalcaemia Other Serious 9/13/2010 1/10/2011 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/10/2010 1/11/2011 Physician Japan
Primary
Secondary
Concomitant
Dermatitis Acneiform Other Serious 7/29/2010 1/11/2011 Physician Japan
Primary
Secondary
Concomitant
Paronychia Other Serious 10/15/2010 1/11/2011 Japan
Primary
Secondary
Concomitant
Dermatitis Acneiform Hospitalization 8/30/2010 1/12/2011 Physician Japan
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 6/28/2010 1/12/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 9/7/2010 1/13/2011 Physician Japan
Primary
Secondary
Concomitant
Colorectal Cancer Death 9/30/2010 1/13/2011 Other Health Professional Japan
Primary
Concomitant
Duodenal Obstruction Death 8/5/2010 1/14/2011 Physician Japan
Primary
Concomitant
Decreased Appetite Other Serious 10/13/2010 1/20/2011 Physician Japan
Primary
Secondary
Concomitant
Colorectal Cancer Other Serious 10/1/2010 1/21/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Rash Other Serious 10/21/2010 71 Female 104 lb 1/24/2011 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 10/15/2010 72 Male 159 lb 1/24/2011 Other Health Professional Japan
Primary
Secondary
Dermatitis Acneiform Hospitalization 8/14/2010 45 Female 119 lb 1/26/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 9/7/2010 76 Male 152 lb 1/27/2011 Other Health Professional Japan
Primary
Concomitant
Neutrophil Count Decreased Death 7/22/2010 75 Female 99 lb 1/28/2011 Physician Japan
Primary
Secondary
Concomitant
Gastric Ulcer Haemorrhage Hospitalization 9/25/2010 64 Male 90 lb 1/28/2011 Physician Japan
Primary
Secondary
Concomitant
Paronychia Hospitalization 9/28/2010 70 Male 141 lb 1/28/2011 Physician Japan
Primary
Secondary
Concomitant
Neoplasm Malignant Life Threatening 10/1/2010 18 Male 106 lb 1/28/2011 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Other Serious 7/27/2010 45 Male 212 lb 1/28/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Acne Hospitalization 11/25/2010 73 Female 143 lb 1/31/2011 Physician Japan
Primary
Concomitant
Ventricular Fibrillation Death 10/20/2010 67 Male 139 lb 1/31/2011 Physician Japan
Primary
Concomitant
Diarrhoea Other Serious 10/15/2010 73 Male 115 lb 2/1/2011 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 11/11/2010 58 Male 121 lb 2/2/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 11/22/2010 70 Female 82 lb 2/2/2011 Physician Japan
Primary
Secondary
Concomitant
Malaise Hospitalization 8/30/2010 75 Female 117 lb 2/3/2011 Physician Japan
Primary
Concomitant
Paronychia Hospitalization 10/1/2010 18 Male 106 lb 2/4/2011 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 10/15/2010 72 Male 159 lb 2/4/2011 Physician Japan
Primary
Secondary
Jaundice Hospitalization 9/30/2010 56 Male 137 lb 2/4/2011 Physician Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 12/7/2010 67 Male 110 lb 2/7/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Paronychia Hospitalization 10/1/2010 18 Male 106 lb 2/8/2011 Other Health Professional Japan
Primary
Concomitant
Dermatitis Acneiform Hospitalization 9/3/2010 64 Male 106 lb 2/8/2011 Other Health Professional Japan
Primary
Concomitant
Dermatitis Acneiform Life Threatening 7/6/2010 64 Male 165 lb 2/8/2011 Physician Japan
Primary
Concomitant
Acne Other Serious 7/5/2010 53 Male 139 lb 2/8/2011 Physician Japan
Primary
Concomitant
Diarrhoea Other Serious 10/17/2010 77 Female 130 lb 2/8/2011 Physician Japan
Primary
Secondary
Concomitant
Metastases To Central Nervous System Hospitalization 8/30/2010 49 Male 143 lb 2/8/2011 Physician Japan
Primary
Secondary
Concomitant
Colorectal Cancer Hospitalization 7/2/2010 69 Male 154 lb 2/8/2011 Physician Japan
Primary
Concomitant
Dermatitis Acneiform Death 11/24/2010 52 Female 117 lb 2/9/2011 Other Health Professional Japan
Primary
Concomitant
Malaise Other Serious 7/28/2010 66 Female 88 lb 2/10/2011 Other Health Professional Japan
Primary
Concomitant
Dry Skin Hospitalization 11/4/2010 41 Female 99 lb 2/10/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Death 9/27/2010 80 Male 139 lb 2/10/2011 Other Health Professional Japan
Primary
Concomitant
Cheilitis Hospitalization 6/28/2010 56 Female 104 lb 2/10/2011 Physician Japan
Primary
Secondary
Concomitant
Decreased Appetite Death 7/29/2010 70 Female 77 lb 2/11/2011 Other Health Professional Japan
Primary
Concomitant
Stomatitis Hospitalization 7/22/2010 75 Female 99 lb 2/11/2011 Other Health Professional Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 10/18/2010 58 Male 165 lb 2/15/2011 Japan
Primary
Secondary
Concomitant
Pancytopenia Death 10/8/2010 76 Male 121 lb 2/16/2011 Physician Japan
Primary
Concomitant
Electrolyte Imbalance Hospitalization 2/1/2011 63 Male 2/17/2011 Physician Japan
Primary
Concomitant
Rash Other Serious 8/18/2010 57 Male 2/17/2011 Physician Japan
Primary
Concomitant
Cystitis Haemorrhagic Hospitalization 1/1/2011 78 Female 2/18/2011 Other Health Professional Japan
Primary
Concomitant
Dermatitis Acneiform Other Serious 9/18/2010 67 Female 99 lb 2/18/2011 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Decreased Death 2/3/2011 76 Female 2/18/2011 Other Health Professional Japan
Primary
Concomitant
Stomatitis Other Serious 10/13/2010 70 Female 106 lb 2/21/2011 Physician Japan
Primary
Concomitant

Drug Data