Gleevec



Indications and Reactions:

Role Indications Reactions
Primary
Chronic Myeloid Leukaemia 59.4%
Gastrointestinal Stromal Tumour 17.6%
Acute Lymphocytic Leukaemia 6.1%
Hypertension 3.9%
Gastric Cancer 1.8%
Pain 1.1%
Malignant Soft Tissue Neoplasm 1.0%
Neoplasm Malignant 1.0%
Diabetes Mellitus 0.9%
Prophylaxis 0.9%
Pulmonary Arterial Hypertension 0.8%
Leukaemia 0.8%
Acute Myeloid Leukaemia 0.7%
Nausea 0.7%
Oedema 0.7%
Constipation 0.6%
Gastritis 0.5%
Depression 0.5%
Atrial Fibrillation 0.5%
Glioblastoma Multiforme 0.5%
Death 51.2%
Vomiting 7.0%
White Blood Cell Count Decreased 4.3%
Neoplasm Malignant 3.8%
Rash 3.2%
Surgery 3.1%
Nausea 3.0%
White Blood Cell Count Increased 2.8%
Weight Increased 2.8%
Pneumonia 2.3%
Weight Decreased 2.1%
Pyrexia 2.1%
Thrombocytopenia 2.1%
Pleural Effusion 1.7%
Diarrhoea 1.6%
Drug Ineffective 1.5%
Oedema Peripheral 1.4%
Malignant Neoplasm Progression 1.4%
Sepsis 1.4%
Chronic Myeloid Leukaemia 1.3%
Secondary
Chronic Myeloid Leukaemia 46.9%
Gastrointestinal Stromal Tumour 16.7%
Hypertension 7.1%
Acute Lymphocytic Leukaemia 5.8%
Prophylaxis 3.0%
Gastritis 2.3%
Dyspepsia 1.9%
Pain 1.6%
Gastric Ulcer 1.6%
Atrial Fibrillation 1.5%
Osteoporosis 1.5%
Insomnia 1.5%
Constipation 1.4%
Oedema 1.3%
Hypothyroidism 1.2%
Gastric Cancer 1.1%
Diabetes Mellitus 1.0%
Nausea 0.9%
Neoplasm Malignant 0.9%
Prophylaxis Against Gastrointestinal Ulcer 0.9%
White Blood Cell Count Decreased 18.1%
Vomiting 14.3%
Death 12.7%
White Blood Cell Count Increased 7.8%
Weight Decreased 5.8%
Rash 5.5%
Pyrexia 5.3%
Weight Increased 4.2%
Thrombocytopenia 3.7%
Nausea 3.3%
Surgery 2.7%
Diarrhoea 2.6%
Neoplasm Malignant 2.1%
Pancytopenia 1.9%
Platelet Count Decreased 1.8%
Pleural Effusion 1.8%
Red Blood Cell Count Decreased 1.8%
Swelling 1.8%
Somnolence 1.7%
Stomatitis 1.5%
Concomitant
Chronic Myeloid Leukaemia 34.4%
Drug Use For Unknown Indication 16.7%
Product Used For Unknown Indication 9.4%
Prophylaxis 6.1%
Gastrointestinal Stromal Tumour 5.4%
Pain 2.5%
Hypertension 2.4%
Multiple Myeloma 2.4%
Pneumonia 2.2%
Pulmonary Hypertension 2.1%
Stent Placement 2.0%
Leukaemia 1.8%
Pulmonary Arterial Hypertension 1.8%
Acute Lymphocytic Leukaemia 1.6%
Neoplasm Malignant 1.6%
Type 2 Diabetes Mellitus 1.5%
Atrial Fibrillation 1.4%
Mastocytosis 1.4%
Nausea 1.4%
Osteoporosis 1.4%
White Blood Cell Count Decreased 13.4%
Vomiting 11.7%
Weight Decreased 10.8%
Thoracic Cavity Drainage 10.4%
Death 6.1%
Pyrexia 5.2%
Syncope 5.2%
Thrombocytopenia 4.8%
White Blood Cell Count Increased 4.3%
Platelet Count Decreased 3.0%
Rash 3.0%
Drug Ineffective 2.6%
Malaise 2.6%
Pain 2.6%
Pain In Extremity 2.6%
Reversible Posterior Leukoencephalopathy Syndrome 2.6%
Vision Blurred 2.6%
Angina Pectoris 2.2%
Fall 2.2%
Pregnancy 2.2%
Interacting
Schizophrenia 35.4%
Acute Lymphocytic Leukaemia 18.9%
Neuralgia 13.0%
Chronic Myeloid Leukaemia 8.4%
Anxiety Disorder 4.0%
Gastrointestinal Stromal Tumour 4.0%
Pulmonary Arterial Hypertension 1.9%
Hypertension 1.6%
Anxiety 1.2%
Back Pain 1.2%
Eosinophilic Leukaemia 1.2%
Gastrointestinal Pain 1.2%
Liver Transplant 1.2%
Malignant Soft Tissue Neoplasm 0.9%
Muscle Spasms 0.9%
Nausea 0.9%
Neoplasm Malignant 0.9%
Pain In Extremity 0.9%
Prophylaxis 0.9%
Tuberculosis 0.9%
Drug Interaction 12.4%
Neuropathy Peripheral 11.4%
Neoplasm Malignant 7.6%
Cough 6.7%
Drug Level Increased 6.7%
Hypoaesthesia 6.7%
Neoplasm Progression 6.7%
Tremor 5.7%
Visual Impairment 5.7%
Vomiting 4.8%
Weight Decreased 4.8%
Immunosuppressant Drug Level Decreased 3.8%
Interstitial Lung Disease 2.9%
Pancytopenia 2.9%
Peritoneal Lesion 1.9%
Retinal Haemorrhage 1.9%
Temporal Lobe Epilepsy 1.9%
Thrombocytopenia 1.9%
Tumour Lysis Syndrome 1.9%
Urticaria 1.9%