Gleevec combined with Hydroxyurea

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pain In Extremity Hospitalization 3/1/2005 54 Female 111 lb 1/11/2006 Physician Malaysia
Primary
Concomitant
Verbal Abuse Hospitalization 12/28/2005 Male 223 lb 1/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 11/19/2005 58 Male 1/27/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/16/2006 Male 4/19/2006 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/21/2006 50 Male 2/22/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Hospitalization 5/2/2006 63 Male 5/16/2006 Other Health Professional United States
Primary
Secondary
Upper Respiratory Tract Infection Hospitalization 5/18/2006 63 Male 5/23/2006 Other Health Professional United States
Primary
Secondary
Drug Exposure During Pregnancy Hospitalization 10/14/2005 20 Female 115 lb 6/17/2006 Physician Chile
Primary
Concomitant
White Blood Cell Count Increased Other Serious 11/1/2005 58 Male 4/26/2006 Physician United States
Primary
Concomitant
Platelet Count Decreased Hospitalization 81 Female 4/26/2006 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/5/2006 61 Male 6/26/2006 Consumer United States
Primary
Secondary
Concomitant
Nausea Hospitalization 7/6/2006 Female 222 lb 7/7/2006 United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 7/21/2006 63 Male 7/24/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Dysfunction Hospitalization 1/1/2005 66 Female 8/7/2006 United States
Primary
Concomitant
Ventricular Dysfunction Hospitalization 1/1/2005 66 Female 8/15/2006 United States
Primary
Concomitant
Victim Of Crime Hospitalization 1/1/2005 66 Female 8/19/2006 United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 7/28/2006 Male 9/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pharyngolaryngeal Abscess Hospitalization 8/11/2006 Male 168 lb 9/7/2006 United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 9/13/2006 Male 9/15/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Speech Disorder Hospitalization 9/13/2006 Male 9/20/2006 Other Health Professional United States
Primary
Secondary
Ventricular Dysfunction Hospitalization 1/1/2005 66 Female 8/19/2006 United States
Primary
Concomitant
Subarachnoid Haemorrhage Hospitalization 6/1/2006 46 Male 10/2/2006 Other Health Professional United States
Primary
Concomitant
Venous Thrombosis Hospitalization 9/18/2006 Male 207 lb 10/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Neurological Symptom Death 10/15/2006 Male 179 lb 10/18/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Thyroid Disorder Hospitalization 10/7/2006 Male 174 lb 10/19/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Nervous System Disorder Hospitalization 10/19/2006 Female 10/20/2006 Other Health Professional United States
Primary
Secondary
Ventricular Dysfunction Hospitalization 1/1/2005 66 Female 10/30/2006 United States
Primary
Concomitant
Nervous System Disorder Hospitalization 10/19/2006 Female 10/30/2006 Other Health Professional United States
Primary
Secondary
Spinal Fracture Hospitalization 12/1/2006 Female 12/1/2006 United States
Primary
Secondary
Spinal Fracture Hospitalization 12/1/2006 Female 12/5/2006 Other Health Professional United States
Primary
Secondary
Spinal Fracture Hospitalization 12/1/2006 Female 12/5/2006 United States
Primary
Secondary
Concomitant
Neuropathy Hospitalization 12/18/2006 Female 12/19/2006 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/27/2006 Female 12/29/2006 United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/18/2007 Female 130 lb 1/19/2007 United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 1/18/2007 Female 130 lb 2/2/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Nuclear Magnetic Resonance Imaging Brain Abnormal Hospitalization 1/16/2007 65 Female 2/9/2007 United States
Primary
Secondary
Concomitant
Thoracic Cavity Drainage Hospitalization 11/20/2006 19 Female 2/21/2007 Physician South Africa
Primary
Concomitant
Tenderness Hospitalization 3/13/2007 4/3/2007 United States
Primary
Secondary
Concomitant
Haemorrhoids Hospitalization 3/25/2007 Male 229 lb 4/9/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Arrest Hospitalization 4/2/2007 Male 111 lb 4/9/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Stomach Discomfort Other Serious 3/1/2007 43 Female 4/16/2007 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 7/17/2006 69 Female 132 lb 5/1/2007 Physician Germany
Primary
Secondary
Concomitant
Thoracic Cavity Drainage Hospitalization 11/20/2006 19 Female 5/5/2007 Physician South Africa
Primary
Concomitant
No Therapeutic Response Other Serious 2/1/2007 22 Male 176 lb 5/5/2007 Pharmacist United Kingdom
Primary
Concomitant
Pleural Effusion Hospitalization 1/4/2006 79 Female 4/24/2007 Physician United States
Primary
Concomitant
Renal Failure Acute Life Threatening 70 Female 4/24/2007 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2006 75 Female 4/24/2007 Physician United States
Primary
Concomitant
Ventricular Dysfunction Hospitalization 1/1/2005 66 Female 6/27/2007 United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 7/6/2007 18 Male 7/17/2007 Pharmacist Brazil
Primary
Concomitant
Productive Cough Other Serious 7/4/2007 49 Male 159 lb 7/20/2007 Physician Turkey
Primary
Concomitant
Productive Cough Other Serious 7/4/2007 49 Male 159 lb 7/27/2007 Physician Turkey
Primary
Concomitant
Premature Labour Other Serious 6/15/2007 18 Female 183 lb 8/31/2007 Physician Canada
Primary
Concomitant
Premature Baby Other Serious 0 Female 5 lb 8/31/2007 Physician Canada
Primary
Concomitant
Ventricular Dysfunction Hospitalization 1/1/2005 66 Female 9/5/2007 United States
Primary
Concomitant
Premature Baby Other Serious 0 Female 5 lb 9/11/2007 Canada
Primary
Concomitant
White Blood Cell Count Increased Other Serious 6/15/2007 18 Female 183 lb 9/11/2007 Canada
Primary
Concomitant
Ventricular Dysfunction Hospitalization 1/1/2005 66 Female 10/1/2007 Physician United States
Primary
Concomitant
Pulmonary Embolism Life Threatening 10/2/2007 Male 170 lb 10/3/2007 United States
Primary
Secondary
Concomitant
Thrombosis Life Threatening 10/2/2007 65 Male 170 lb 10/4/2007 United States
Primary
Secondary
Concomitant
Loss Of Consciousness Death 11/2/2007 45 Male 229 lb 11/6/2007 United States
Primary
Secondary
Concomitant
Thrombosis Death 11/2/2007 45 Male 229 lb 11/12/2007 United States
Primary
Secondary
Concomitant
Weight Increased Death 8/2/2007 49 Female 165 lb 11/13/2007 United States
Primary
Secondary
Concomitant
Tachycardia Other Serious Male 11/21/2007 Consumer United Kingdom
Primary
Concomitant
Lobar Pneumonia Hospitalization 12/1/2007 72 Male 201 lb 12/6/2007 United States
Primary
Secondary
Concomitant
Malaise Death 1/24/2008 Female 1/31/2008 Physician Germany
Primary
Secondary
Disease Progression Hospitalization 51 Male 2/6/2008 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Other Serious 9/8/2006 64 Male 108 lb 2/8/2008 Physician Canada
Primary
Secondary
White Blood Cell Count Increased Hospitalization 3/12/2008 64 Female 146 lb 3/13/2008 Consumer United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/29/2008 60 Male 165 lb 4/2/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Stomach Discomfort Other Serious 3/12/2004 65 Male 4/12/2008 Other Health Professional United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 2/2/2006 66 Male 4/13/2008 Other Health Professional
Primary
Concomitant
Refusal Of Treatment By Relative Life Threatening 4/13/2008 Male 185 lb 4/14/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 3/22/2008 Male 218 lb 3/24/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Other Serious 5/2/2002 88 Male 4/23/2008 Other Health Professional United Kingdom
Primary
Concomitant
Skin Erosion Other Serious 1/1/2006 Female 5/1/2008 Consumer Germany
Primary
Concomitant
Skin Erosion Other Serious 1/1/2006 Female 5/2/2008 Consumer Germany
Primary
Concomitant
Lung Disorder Hospitalization 58 Male 5/9/2008 Other Health Professional Canada
Primary
Concomitant
Rash Other Serious 5/2/2002 88 Male 5/27/2008 Other Health Professional United Kingdom
Primary
Concomitant
Lung Disorder Hospitalization 58 Male 6/6/2008 Other Health Professional Canada
Primary
Concomitant
Weight Decreased Hospitalization 6/5/2008 Female 176 lb 6/9/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Ankle Fracture Hospitalization 2/20/2007 74 Male 7/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Lung Disorder Hospitalization 3/1/2008 58 Male 7/14/2008 Other Health Professional Canada
Primary
Concomitant
Lung Disorder Hospitalization 3/1/2008 58 Male 7/15/2008 Other Health Professional Canada
Primary
Concomitant
Stillbirth Death 7/17/2008 Other Health Professional United Kingdom
Primary
Concomitant
Premature Labour Other Serious 25 Female 7/17/2008 Physician United Kingdom
Primary
Concomitant
Premature Labour Other Serious 25 Female 7/17/2008 Physician United Kingdom
Primary
Concomitant
Grand Mal Convulsion Hospitalization 7/4/2008 Male 7/15/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Suicidal Ideation Hospitalization 7/4/2008 Male 7/15/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 7/15/2008 50 Male 168 lb 7/28/2008 United States
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 5/21/2003 58 Male 8/13/2008 Physician United Kingdom
Primary
Concomitant
Ankle Fracture Hospitalization 74 Male 8/13/2008 Other Health Professional United Kingdom
Primary
Secondary
Visual Field Defect Hospitalization 7/27/2008 43 Male 207 lb 8/14/2008 United States
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 8/10/2008 35 Male 4 lb 8/15/2008 United States
Primary
Secondary
Concomitant
Ankle Fracture Hospitalization 2/20/2007 74 Male 8/20/2008 Other Health Professional United Kingdom
Primary
Secondary
Urinary Incontinence Hospitalization 7/29/2008 40 Male 172 lb 8/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Erosion Other Serious 1/1/2006 Female 9/23/2008 Consumer Germany
Primary
Concomitant
White Blood Cell Count Increased Other Serious 76 Male 9/25/2008 Other Health Professional Turkey
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2004 40 Male 10/7/2008 Other Health Professional Turkey
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 90 Female 12/12/2008 Other Health Professional Switzerland
Primary
Concomitant
Treatment Noncompliance Other Serious Female 3/24/2009 Physician South Africa
Primary
Concomitant
Thrombocytopenia Other Serious 9/1/2005 Male 5/8/2009 Physician South Africa
Primary
Concomitant
Skin Lesion Other Serious 8/25/2008 70 Male 8/18/2009 Physician Japan
Primary
Concomitant
Skin Lesion Other Serious 8/25/2008 70 Male 10/12/2009 Physician Japan
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 6/1/2009 Female 134 lb 10/19/2009 Physician South Africa
Primary
Concomitant
Treatment Noncompliance Other Serious Female 10/26/2009 Other Health Professional South Africa
Primary
Concomitant
Thrombocytopenia Other Serious 9/1/2005 Male 11/4/2009 Physician South Africa
Primary
Concomitant
Vomiting Other Serious 11/1/2009 33 Male 11/12/2009 Consumer Germany
Primary
Secondary
Transplant Other Serious 64 Male 185 lb 11/24/2009 United States
Primary
Concomitant
Sepsis Death 45 Female 11/30/2009 Physician Malaysia
Primary
Secondary
Wheezing Hospitalization 54 Male 1/22/2010 Other Health Professional China
Primary
Concomitant
Blast Crisis In Myelogenous Leukaemia Death Male 2/15/2010 Malaysia
Primary
Concomitant
Swelling Other Serious 7/3/2001 3 Female 4/12/2010 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Surgery Other Serious 4/5/2010 61 Female 118 lb 5/12/2010 Physician United States
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious Female 108 lb 6/22/2010 Physician Malaysia
Primary
Concomitant
White Blood Cell Count Increased Other Serious 25 Female 6/25/2010 Physician Brazil
Primary
Concomitant
White Blood Cell Count Increased Other Serious 6/15/2007 18 Female 183 lb 6/29/2010 Canada
Primary
Concomitant
Subcutaneous Nodule Other Serious 54 Male 7/2/2010 Other Health Professional Hungary
Primary
Concomitant
Malignant Neoplasm Progression Other Serious Male 8/5/2010 United States
Primary
Concomitant
Ventricular Hypokinesia Other Serious Male 8/12/2010 United States
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 11/25/2008 83 Female 8/16/2010 Physician Japan
Primary
Concomitant
Interacting
Drug Exposure During Pregnancy Other Serious Female 108 lb 9/7/2010 Physician Malaysia
Primary
Concomitant
Dysstasia Other Serious 10/9/2010 39 Male 10/20/2010 Physician India
Primary
Concomitant
Pyrexia Other Serious 1/1/2006 61 Male 12/13/2010 Other Health Professional United States
Primary
Concomitant
Diarrhoea Hospitalization 6/1/2010 32 Male 1/31/2011 Physician India
Primary
Concomitant
Motor Dysfunction Other Serious Female 139 lb 5/6/2011 Physician Germany
Primary
Secondary
Concomitant
Blood Creatinine Increased Other Serious 8/27/2008 57 Male 5/10/2011 Physician South Africa
Primary
Secondary
Concomitant
Death Death 8/14/2005 31 Female 6/6/2011 Philippines
Primary
Concomitant
Metastases To Lymph Nodes Hospitalization 10/22/2007 52 Male 187 lb 6/4/2011 Other Health Professional Germany
Primary
Concomitant
Weight Decreased Death 53 Male 6/28/2011 United States
Primary
Secondary
Concomitant
Speech Disorder Hospitalization 6/4/2011 70 Female 8/17/2011 Physician United States
Primary
Concomitant
Decreased Appetite Other Serious Male 9/5/2011 Consumer United States
Primary
Secondary
Concomitant
Nausea Life Threatening Male 9/21/2011 Consumer United States
Primary
Secondary
Concomitant
Speech Disorder Other Serious Female 9/22/2011 Other Health Professional Hungary
Primary
Secondary
Concomitant
Epistaxis Other Serious 7/29/2011 78 Male 98 lb 9/23/2011 Pharmacist Brazil
Primary
Concomitant
Weight Decreased Hospitalization 53 Male 11/21/2011 United States
Primary
Secondary
Concomitant
Hepatosplenomegaly Death 10/27/2011 70 Female 2/17/2012 Physician Mexico
Primary
Concomitant
Venous Insufficiency Other Serious Female 3/13/2012 Consumer Mexico
Primary
Secondary
Respiratory Failure Other Serious Female 3/19/2012 Consumer Mexico
Primary
Secondary
Neoplasm Progression Death Male 3/27/2012 Consumer United States
Primary
Concomitant
Pneumonia Other Serious 9/27/2011 29 Female 3/28/2012 Physician Mexico
Primary
Secondary
Surgery Other Serious 3/10/2009 64 Male 7/8/2009 Physician United States
Primary
Concomitant
Neuropathy Peripheral Other Serious 7/3/2008 71 Male 7/8/2009 Physician United States
Primary
Concomitant
Dermatitis Allergic Other Serious 1/1/2008 5 Female 60 lb 7/8/2009 Physician United States
Primary
Secondary
Concomitant
Bone Marrow Failure Other Serious Male 7/8/2009 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Hospitalization 11/1/2008 83 Female 106 lb 7/8/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Bone Marrow Failure Other Serious Male 7/8/2009 Other Health Professional United States
Primary
Concomitant
Nausea Hospitalization 11/1/2008 83 Female 106 lb 7/8/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 32 Male 5/16/2011 Other Health Professional United States
Primary
Concomitant
Paraesthesia Other Serious 7/3/2008 71 Male 7/8/2009 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 3/10/2009 64 Male 5/28/2010 Physician United States
Primary
Concomitant

Drug Data