Allopurinol combined with Gleevec

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hypertension Life Threatening 10/3/2005 60 Male 388 lb 1/19/2006 Physician Russian Federation
Primary
Concomitant
Thrombocytopenia Other Serious 12/5/2005 81 Male 165 lb 2/15/2006 Physician Germany
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 9/2/2005 57 Male 143 lb 2/15/2006 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 12/5/2005 81 Male 165 lb 3/1/2006 Physician Germany
Primary
Secondary
Concomitant
Septic Shock Hospitalization 10/30/2005 51 Male 3/2/2006 Pharmacist New Zealand
Primary
Concomitant
Lip Dry Hospitalization 10/1/2005 Male 4/13/2006 United States
Primary
Concomitant
Vomiting Other Serious 3/1/2004 22 Female 1/27/2006 Other Health Professional United States
Primary
Concomitant
X-ray Abnormal Life Threatening 2/1/2006 71 Male 216 lb 5/24/2006 Physician Germany
Primary
Concomitant
Tenderness Other Serious 12/14/2005 47 Female 5/31/2006 United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/1/2006 84 Female 6/17/2006 Other Health Professional United States
Primary
Concomitant
Pyrexia Other Serious 4/24/2006 46 Male 6/21/2006 Physician France
Primary
Concomitant
Paraesthesia Other Serious Female 4/26/2006 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 5/1/2006 84 Female 6/29/2006 Other Health Professional United States
Primary
Concomitant
Surgery Life Threatening 4/26/2006 80 Female 172 lb 6/30/2006 Physician France
Primary
Concomitant
Lip Dry Hospitalization 10/1/2005 Male 6/30/2006 Physician United States
Primary
Concomitant
Sigmoidectomy Hospitalization 1/1/2003 73 Female 7/10/2006 United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 4/9/2002 70 Male 143 lb 7/28/2006 Physician Japan
Primary
Concomitant
Drug Ineffective Male 163 lb 8/4/2006 Physician United States
Primary
Concomitant
Pregnancy Death 30 Female 6/17/2006 Physician United States
Primary
Concomitant
Pleural Effusion Hospitalization 78 Male 6/17/2006 Physician United States
Primary
Concomitant
Urticaria Hospitalization 10/19/2005 62 Female 6/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Other Serious 4/1/2006 75 Male 227 lb 9/1/2006 United States
Primary
Concomitant
Weight Increased Other Serious 9/18/2006 69 Female 181 lb 10/3/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/15/2006 47 Male 10/5/2006 Physician Japan
Primary
Concomitant
Hypophosphataemia Hospitalization 7/5/2006 69 Male 10/5/2006 United Kingdom
Primary
Concomitant
Thrombosis Life Threatening 10/1/2006 46 Male 10/31/2006 Physician United States
Primary
Concomitant
Stridor Other Serious 5/15/2006 47 Male 11/1/2006 Physician Japan
Primary
Concomitant
Stridor Other Serious 5/15/2006 47 Male 11/2/2006 Physician Japan
Primary
Concomitant
Treatment Noncompliance Life Threatening 10/1/2006 46 Male 11/1/2006 Physician United States
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 4/1/2006 75 Male 227 lb 11/13/2006 United States
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 9/1/2006 66 Female 11/18/2006 Physician Japan
Primary
Secondary
Gastrointestinal Haemorrhage Hospitalization 9/1/2005 45 Male 11/21/2006 Physician Australia
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 3/1/2006 72 Male 12/12/2006 Physician Argentina
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 6/29/2004 69 Male 12/18/2006 Physician Japan
Primary
Concomitant
Myalgia Other Serious 1/17/2007 36 Male 225 lb 3/3/2007 Physician Switzerland
Primary
Concomitant
Mental Status Changes Other Serious 1/1/2006 79 Male 169 lb 3/8/2007 United States
Primary
Concomitant
Mental Status Changes Other Serious 1/1/2006 79 Male 169 lb 3/8/2007 United States
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 9/1/2006 66 Female 119 lb 4/3/2007 Japan
Primary
Secondary
Tumour Lysis Syndrome Other Serious 1/1/2006 82 Female 238 lb 4/25/2007 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 9/18/2006 69 Female 181 lb 4/27/2007 Other Health Professional United States
Primary
Concomitant
No Therapeutic Response Other Serious 2/1/2007 22 Male 176 lb 5/5/2007 Pharmacist United Kingdom
Primary
Concomitant
Cellulitis Other Serious 3/18/2007 70 Male 5/5/2007 Physician United States
Primary
Concomitant
Thyroid Operation Other Serious 1/1/2005 Male 179 lb 5/7/2007 Physician Germany
Primary
Secondary
Concomitant
Sudden Death Death 3/30/2007 78 Male 190 lb 5/8/2007 France
Primary
Concomitant
Somnolence Other Serious 1/1/2003 79 Male 77 lb 5/13/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 4/9/2002 70 Male 143 lb 5/30/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/1/2007 75 Male 6/19/2007 Physician Japan
Primary
Concomitant
Paraesthesia Other Serious Female 4/24/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 3/1/2006 61 Female 143 lb 4/24/2007 Physician United States
Primary
Concomitant
Oedema Hospitalization 1/1/2005 86 Female 4/24/2007 Physician United States
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 2/27/2006 28 Female 155 lb 4/24/2007 Other Health Professional United States
Primary
Concomitant
Pharyngolaryngeal Pain Other Serious 11/3/2006 62 Male 4/24/2007 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization Female 4/24/2007 Physician United States
Primary
Concomitant
Pneumonitis Other Serious 12/9/2006 60 Male 4/24/2007 Physician United States
Primary
Concomitant
Somnolence Other Serious 1/1/2003 79 Male 77 lb 7/6/2007 Physician Japan
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 9/1/2006 66 Female 119 lb 7/14/2007 Japan
Primary
Secondary
Vomiting Other Serious 1/1/2007 79 Female 7/14/2007 Switzerland
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 8/11/2006 66 Female 119 lb 7/21/2007 Japan
Primary
Secondary
White Blood Cell Count Increased Other Serious 2/1/2007 75 Male 7/24/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/1/2003 54 Male 150 lb 8/4/2007 Other Health Professional Japan
Primary
Concomitant
Ventricular Dysfunction Other Serious 69 Female 8/10/2007 Physician United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 3/1/2007 23 Male 67 lb 9/1/2007 Physician United States
Primary
Concomitant
Rash Pruritic Hospitalization 7/26/2007 53 Female 140 lb 8/31/2007 Physician United States
Primary
Concomitant
Respiratory Arrest Other Serious 6/1/2007 81 Female 9/11/2007 Physician United Kingdom
Primary
Concomitant
Metastasis Other Serious 6/6/2007 61 Male 9/19/2007 Physician France
Primary
Concomitant
Respiratory Arrest Life Threatening 9/4/2007 77 Male 53 lb 10/2/2007 Other Health Professional Japan
Primary
Concomitant
Hypotension Other Serious 8/20/2007 76 Male 370 lb 10/30/2007 Physician United States
Primary
Concomitant
Skin Ulcer Other Serious 3/28/2007 29 Male 163 lb 12/14/2007 Physician Japan
Primary
Concomitant
Urine Output Decreased Other Serious 11/13/2004 84 Male 165 lb 1/19/2008 United Kingdom
Primary
Concomitant
Chromosome Analysis Abnormal Hospitalization 12/4/2007 51 Male 2/1/2008 Physician United States
Primary
Concomitant
Reticulocyte Count Increased Other Serious 11/2/2007 66 Female 130 lb 3/15/2008 Physician Japan
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 1/1/2008 Male 4/10/2008 Other Health Professional France
Primary
Secondary
Concomitant
Tenderness Hospitalization 8/1/2007 45 Male 207 lb 4/11/2008 Norway
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 2/2/2006 66 Male 4/13/2008 Other Health Professional
Primary
Concomitant
Rash Morbilliform Hospitalization 3/3/2008 55 Male 4/23/2008 France
Primary
Secondary
Platelet Count Decreased Other Serious 2/5/2004 46 Female 4/24/2008 Other Health Professional United Kingdom
Primary
Concomitant
Platelet Count Decreased Other Serious 2/5/2004 46 Female 4/24/2008 Other Health Professional United Kingdom
Primary
Concomitant
Transfusion Hospitalization 7/1/2007 73 Male 4/29/2008 Physician Spain
Primary
Secondary
Concomitant
Pelvic Fracture Other Serious 8/15/2002 68 Female 5/2/2008 Other Health Professional United Kingdom
Primary
Concomitant
Syncope Death 1/22/2008 57 Female 141 lb 5/21/2008 Physician United Kingdom
Primary
Concomitant
Therapeutic Response Decreased Other Serious 8/29/2007 5/29/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pelvic Fracture Other Serious 8/15/2002 68 Female 5/23/2008 Other Health Professional United Kingdom
Primary
Concomitant
Lichenification Other Serious 3/1/2008 Female 183 lb 6/9/2008 Physician Germany
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 Male 183 lb 6/16/2008 Physician Canada
Primary
Concomitant
Injury Death 6/12/2008 Male 6/18/2008 United States
Primary
Concomitant
Injury Death 6/12/2008 Male 6/23/2008 United States
Primary
Concomitant
Rash Hospitalization 5/6/2008 Male 73 lb 7/24/2008 Physician Japan
Primary
Concomitant
Chronic Myeloid Leukaemia Other Serious 4/1/2008 48 Male 7/28/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/28/2008 Male 8/8/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 3/28/2008 Female 8/7/2008 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/1/2008 Female 8/12/2008 Physician United States
Primary
Concomitant
Interacting
Neutrophil Count Decreased Other Serious 5/21/2003 58 Male 8/13/2008 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 6/24/2008 Female 71 lb 8/15/2008 Physician Japan
Primary
Concomitant
Therapy Responder Other Serious Female 8/26/2008 Physician Israel
Primary
Concomitant
Renal Failure Other Serious 3/1/2008 Female 9/26/2008 Physician France
Primary
Concomitant
Thrombocytopenia Other Serious 5/30/2008 Female 10/1/2008 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 3/1/2008 Female 10/13/2008 Physician France
Primary
Concomitant
Hepatitis Toxic Hospitalization 8/26/2008 48 Male 10/20/2008 Physician Belgium
Primary
Concomitant
Skin Ulcer Other Serious 29 Female 12/3/2008 Other Health Professional Greece
Primary
Concomitant
Renal Failure Other Serious Male 12/12/2008 Other Health Professional United States
Primary
Concomitant
Urine Bilirubin Increased Other Serious 7/10/2008 Male 176 lb 12/19/2008 United States
Primary
Concomitant
Pneumonia Aspiration Other Serious 9/1/2008 Male 139 lb 1/23/2009 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2007 Male 216 lb 2/22/2009 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2007 Male 216 lb 2/26/2009 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 2/15/2008 Female 325 lb 3/5/2009 Physician United States
Primary
Concomitant
Pain In Extremity Other Serious 1/15/2009 Female 3/20/2009 Other Health Professional Italy
Primary
Concomitant
Vomiting Disability 2/25/2009 72 Female 4/14/2009 Other Health Professional United Kingdom
Primary
Concomitant
Febrile Neutropenia Other Serious 72 Male 4/21/2009 Other Health Professional Greece
Primary
Secondary
Concomitant
Intentional Overdose 4/1/2009 57 Male 204 lb 6/10/2009 Consumer United States
Primary
Concomitant
Metastases To Liver Death 10/17/2008 Male 134 lb 7/31/2009 United States
Primary
Concomitant
Urticaria Other Serious 3/1/2009 75 Female 8/5/2009 Other Health Professional France
Primary
Interacting
Renal Impairment Other Serious 6/9/2008 Male 243 lb 8/10/2009 Physician Germany
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 4/11/2008 Male 287 lb 8/10/2009 Other Health Professional United States
Primary
Concomitant
Nausea Hospitalization 55 Female 8/28/2009 Russian Federation
Primary
Concomitant
Vital Capacity Decreased Other Serious 12/1/2004 Male 9/1/2009 United States
Primary
Concomitant
Thyroid Cancer Metastatic Hospitalization 6/1/2009 Male 10/6/2009 Physician Sweden
Primary
Concomitant
White Blood Cell Count Increased Other Serious 7/27/2009 Male 10/7/2009 United States
Primary
Concomitant
Rash Hospitalization 8/18/2009 Female 10/8/2009 Other Health Professional Norway
Primary
Concomitant
Interacting
Death Death Female 11/6/2009 United States
Primary
Secondary
Concomitant
Respiratory Arrest Other Serious 6/1/2007 81 Female 11/9/2009 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 11/1/2009 33 Male 11/12/2009 Consumer Germany
Primary
Secondary
Muscular Weakness Other Serious 11/13/2009 Female 11/30/2009 United States
Primary
Concomitant
Haematochezia Other Serious 10/30/2009 44 Male 160 lb 12/3/2009 United States
Primary
Concomitant
Muscular Weakness Other Serious 11/13/2009 Female 12/7/2009 United States
Primary
Concomitant
Ischaemic Stroke Hospitalization 12/7/2009 Male 212 lb 1/8/2010 Physician United States
Primary
Secondary
Concomitant
Ischaemic Stroke Hospitalization 12/7/2009 Male 212 lb 1/11/2010 Physician United States
Primary
Secondary
Concomitant
Arthritis Reactive Other Serious 12/1/2009 Female 1/19/2010 Physician Philippines
Primary
Concomitant
Ischaemic Stroke Hospitalization 12/7/2009 Male 212 lb 1/26/2010 Physician United States
Primary
Secondary
Concomitant
Ischaemic Stroke Hospitalization 12/7/2009 72 Male 1/19/2010 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 12/1/2009 Female 2/2/2010 United States
Primary
Concomitant
Ischaemic Stroke Hospitalization 12/7/2009 72 Male 2/5/2010 United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 2/13/2010 Female 168 lb 2/24/2010 United States
Primary
Concomitant
Renal Impairment Other Serious 4/1/2009 Female 117 lb 2/26/2010 Other Health Professional Japan
Primary
Concomitant
Ischaemic Stroke Hospitalization 12/7/2009 Male 212 lb 3/2/2010 Physician United States
Primary
Secondary
Concomitant
Skin Disorder Other Serious 2/9/2010 Male 3/19/2010 United States
Primary
Concomitant
Death Death Male 3/22/2010 United States
Primary
Concomitant
Death Death Male 3/22/2010 United States
Primary
Concomitant
Death Death 8/2/2009 Male 179 lb 3/24/2010 United States
Primary
Concomitant
Renal Impairment Other Serious 1/1/2009 Female 117 lb 3/26/2010 Other Health Professional Japan
Primary
Concomitant
Myelofibrosis Other Serious 3/11/2010 Male 3/29/2010 Other Health Professional Italy
Primary
Concomitant
Urine Abnormality Other Serious 1/28/2010 Male 3/31/2010 Physician United States
Primary
Concomitant
Diarrhoea Hospitalization 3/29/2010 85 Male 162 lb 3/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 1/1/2009 73 Female 117 lb 4/8/2010 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 8/14/2004 70 Female 4/12/2010 Physician Japan
Primary
Secondary
Concomitant
Death Death 2/16/2010 63 Male 4/19/2010 United States
Primary
Concomitant
Pleural Effusion Other Serious 3/19/2010 42 Female 4/20/2010 Other Health Professional Switzerland
Primary
Concomitant
Pneumonia Death Male 4/23/2010 United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/14/2010 57 Female 4/26/2010 Physician France
Primary
Secondary
Concomitant
Ischaemic Stroke Hospitalization 12/7/2009 72 Male 212 lb 5/11/2010 Physician United States
Primary
Secondary
Concomitant
Surgery Other Serious Male 5/14/2010 Physician United States
Primary
Concomitant

Drug Data