Gleevec combined with Levothyroxine Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Other Serious 5/3/2004 73 Male 184 lb 2/13/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 5/3/2004 73 Male 184 lb 4/20/2006 Physician United States
Primary
Secondary
Concomitant
Thyroid Operation Other Serious 5/1/2006 71 Male 8/11/2006 Physician Germany
Primary
Concomitant
Thyroid Operation Other Serious 5/1/2006 71 Male 8/11/2006 Physician Germany
Primary
Concomitant
Non-hodgkin's Lymphoma Unspecified Histology Aggressive Life Threatening 6/1/2006 58 Female 143 lb 9/22/2006 France
Primary
Concomitant
Temperature Intolerance Hospitalization 73 Female 10/2/2006 Netherlands
Primary
Secondary
Concomitant
Tongue Coated Life Threatening 9/27/2006 76 Female 154 lb 10/10/2006 Physician Canada
Primary
Concomitant
Fall Hospitalization 1/1/2006 Female 10/19/2006 United States
Primary
Secondary
Sepsis Hospitalization 1/1/2006 86 Female 10/27/2006 Physician United States
Primary
Secondary
Urosepsis Hospitalization 1/1/2006 86 Female 11/11/2006 Physician United States
Primary
Secondary
Stomatitis Other Serious 5/1/2006 68 Female 161 lb 11/14/2006 Physician Germany
Primary
Concomitant
Vomiting Life Threatening 11/1/2006 58 Female 150 lb 1/6/2007 France
Primary
Secondary
Concomitant
Swelling Hospitalization 1/16/2007 78 Male 194 lb 1/23/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Stillbirth Other Serious 29 Female 2/13/2007 Physician Russian Federation
Primary
Secondary
Stillbirth Other Serious 1/1/2006 29 Female 2/14/2007 Physician Russian Federation
Primary
Secondary
Foetal Growth Retardation Other Serious 29 Female 2/20/2007 Physician Russian Federation
Primary
Secondary
Foetal Growth Retardation Other Serious 29 Female 2/20/2007 Physician Russian Federation
Primary
Secondary
Vomiting Hospitalization 1/15/2007 83 Female 139 lb 4/2/2007 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2006 75 Female 5/23/2007 Physician
Primary
Concomitant
Temperature Intolerance Other Serious 73 Female 6/7/2007 Other Health Professional United States
Primary
Secondary
Thyroxine Increased Other Serious 73 Male 8/21/2007 Other Health Professional Greece
Primary
Secondary
Tumour Lysis Syndrome Hospitalization 7/1/2007 71 Male 186 lb 8/28/2007 Physician United States
Primary
Concomitant
Cytolytic Hepatitis Hospitalization 7/31/2007 46 Female 10/8/2007 Other Health Professional France
Primary
Secondary
Hypotension Other Serious 8/20/2007 76 Male 370 lb 10/30/2007 Physician United States
Primary
Concomitant
Neutropenia Disability 2/15/2007 Male 148 lb 12/12/2007 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Death 58 Male 12/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Muscle Atrophy Death 80 Male 110 lb 1/25/2008 Physician United Kingdom
Primary
Concomitant
Muscle Atrophy Other Serious 80 Male 110 lb 2/1/2008 Physician United Kingdom
Primary
Concomitant
Hypothyroidism Other Serious 12/18/2006 61 Female 2/13/2008 Physician Norway
Primary
Concomitant
Vision Blurred Other Serious 9/8/2006 Male 3/18/2008 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 9/8/2006 Male 3/27/2008 Consumer United States
Primary
Concomitant
Bone Marrow Failure Other Serious 10/1/2007 Male 4/22/2008 Physician Australia
Primary
Secondary
Concomitant
Therapeutic Response Delayed Other Serious 1/1/1999 Female 145 lb 7/3/2008 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 4/1/2008 Female 8/12/2008 Physician United States
Primary
Concomitant
Interacting
Blast Crisis In Myelogenous Leukaemia Death Female 9/23/2008 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Delayed Other Serious 1/1/1999 Female 155 lb 9/24/2008 Physician United States
Primary
Concomitant
Hypothyroidism Other Serious Female 5/7/2009 Pharmacist United States
Primary
Concomitant
Hypothyroidism Other Serious 4/27/2009 Female 5/12/2009 Pharmacist United States
Primary
Concomitant
Refractory Anaemia Other Serious 10/31/2008 Female 6/26/2009 Physician Australia
Primary
Concomitant
Surgery Other Serious 6/22/2009 Female 183 lb 7/16/2009 Physician United States
Primary
Concomitant
Red Blood Cell Count Decreased Other Serious 6/22/2009 Female 183 lb 10/20/2009 Physician United States
Primary
Concomitant
Presyncope Hospitalization 7/20/2009 Male 10/30/2009 United States
Primary
Concomitant
Eye Haemorrhage Other Serious Male 11/11/2009 United States
Primary
Concomitant
Sinus Bradycardia Life Threatening 1/30/2009 86 Female 12/8/2009 Other Health Professional France
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 37 Female 12/14/2009 United States
Primary
Concomitant
Autoimmune Hepatitis Hospitalization 7/31/2007 46 Female 1/22/2010 Pharmacist France
Primary
Secondary
Metastases To Lung Other Serious Female 3/4/2010 Physician Australia
Primary
Concomitant
Metastases To Lung Other Serious 2/1/2006 Female 3/17/2010 Physician Australia
Primary
Concomitant
Pneumonia Death 1/14/2010 Male 3/19/2010 United States
Primary
Concomitant
Oxygen Saturation Decreased Hospitalization Male 5/18/2010 Consumer United States
Primary
Concomitant
Vomiting Life Threatening 5/20/2009 53 Female 5/21/2010 Other Health Professional France
Primary
Concomitant
Periorbital Oedema Other Serious 12/1/2002 65 Male 6/9/2010 New Zealand
Primary
Secondary
Concomitant
Immunosuppressant Drug Level Decreased Other Serious 5/1/2010 Female 6/10/2010 Physician Germany
Primary
Concomitant
Interacting
Uterine Disorder Hospitalization 69 Female 6/22/2010 Physician France
Primary
Concomitant
Immunosuppressant Drug Level Decreased Other Serious 5/1/2010 Female 6/30/2010 Physician Germany
Primary
Concomitant
Interacting
Uterine Disorder Hospitalization 6/10/2010 69 Female 128 lb 7/6/2010 Physician France
Primary
Concomitant
Ruptured Cerebral Aneurysm Life Threatening 11/28/2009 Female 187 lb 8/9/2010 Physician Germany
Primary
Concomitant
Syncope Other Serious 1/14/2010 82 Female 8/20/2010 United States
Primary
Concomitant
Interacting
Surgery Other Serious 6/1/2010 55 Female 10/27/2010 Physician Russian Federation
Primary
Concomitant
Syncope Hospitalization Female 11/26/2010 United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2003 72 Male 12/1/2010 Consumer United States
Primary
Concomitant
Surgery Other Serious 6/1/2010 55 Female 1/3/2011 Physician Russian Federation
Primary
Concomitant
Arthralgia Other Serious 1/1/2003 72 Male 1/31/2011 Physician United States
Primary
Concomitant
Chest Pain Hospitalization 1/4/2009 79 Male 2/18/2011 Physician Germany
Primary
Secondary
Concomitant
Diarrhoea Other Serious Female 3/30/2011 United States
Primary
Concomitant
Oedema Peripheral Death 95 Male 3/30/2011 Consumer United States
Primary
Concomitant
Diarrhoea Other Serious Male 5/10/2011 Physician United States
Primary
Concomitant
Blood Creatinine Increased Other Serious 8/27/2008 57 Male 5/10/2011 Physician South Africa
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 4/14/2010 79 Male 141 lb 5/16/2011 Physician France
Primary
Secondary
Concomitant
Blood Creatinine Increased Other Serious Female 123 lb 5/17/2011 Consumer United States
Primary
Concomitant
Nasopharyngitis Other Serious 3/1/2011 43 Female 5/31/2011 Taiwan, Province Of China
Primary
Concomitant
Abdominal Pain Upper Other Serious 5/1/2011 50 Female 6/7/2011 Consumer Germany
Primary
Concomitant
Thyrotoxic Crisis Hospitalization 5/1/2011 42 Female 6/1/2011 Consumer Germany
Primary
Secondary
Concomitant
Cerebral Atrophy Other Serious 5/31/2008 74 Female 6/14/2011 United States
Primary
Concomitant
Eyelid Oedema Life Threatening 10/24/2003 69 Female 99 lb 6/23/2011 Physician Japan
Primary
Secondary
Concomitant
Myalgia Other Serious 4/1/2011 77 Female 112 lb 6/30/2011 Consumer Germany
Primary
Concomitant
Liver Disorder Other Serious 4/13/2009 76 Male 152 lb 7/5/2011 Physician Japan
Primary
Secondary
Concomitant
Gastrointestinal Disorder Other Serious Male 7/19/2011 Physician United States
Primary
Concomitant
Muscle Spasms 1/1/2005 61 Male 179 lb 7/26/2011 Consumer Germany
Primary
Secondary
Concomitant
Gastrointestinal Ulcer Other Serious 4/29/2011 57 Male 253 lb 7/26/2011 Physician United States
Primary
Secondary
Concomitant
Psoriatic Arthropathy Other Serious 4/1/2011 57 Female 250 lb 8/8/2011 Consumer United States
Primary
Concomitant
Muscle Fatigue Other Serious 5/13/2011 61 Female 141 lb 8/8/2011 Physician France
Primary
Concomitant
Myalgia Other Serious 4/1/2011 77 Female 112 lb 8/16/2011 Physician Germany
Primary
Concomitant
Liver Disorder Other Serious 4/13/2009 76 Male 152 lb 8/24/2011 Physician Japan
Primary
Secondary
Concomitant
Intervertebral Disc Protrusion Other Serious 1/1/2010 55 Female 152 lb 8/29/2011 Consumer Germany
Primary
Concomitant
Arterial Disorder Hospitalization 1/1/2011 79 Female 146 lb 8/30/2011 Physician France
Primary
Concomitant
Blood Creatine Phosphokinase Increased Hospitalization 7/11/2011 69 Female 9/14/2011 Physician Germany
Primary
Concomitant
Death Life Threatening 8/25/2011 74 Male 183 lb 9/20/2011 Physician Australia
Primary
Concomitant
Concomitant Disease Progression Life Threatening 6/27/2011 58 Female 159 lb 9/23/2011 Physician Germany
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 2/4/2011 77 Female 104 lb 9/28/2011 Consumer United States
Primary
Concomitant
Vasculitis Hospitalization 74 Male 10/12/2011 Other Health Professional Sweden
Primary
Concomitant
Headache Other Serious 6/1/2011 74 Female 10/21/2011 Physician Belgium
Primary
Concomitant
Death Other Serious Male 10/28/2011 Consumer United States
Primary
Concomitant
Septic Shock Death 8/25/2011 74 Male 183 lb 12/5/2011 Other Health Professional Australia
Primary
Concomitant
Concomitant Disease Progression Life Threatening 6/27/2011 58 Female 159 lb 12/6/2011 Physician Germany
Primary
Secondary
Concomitant
Ureteric Cancer Other Serious Female 12/6/2011 Physician Italy
Primary
Concomitant
Pulmonary Embolism Other Serious Female 104 lb 12/23/2011 Physician United States
Primary
Concomitant
Hypertensive Crisis Hospitalization 8/1/2011 74 Female 110 lb 12/26/2011 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Hospitalization Female 104 lb 1/2/2012 United States
Primary
Concomitant
Pericardial Effusion Other Serious 11/10/2011 57 Female 106 lb 1/2/2012 Physician France
Primary
Secondary
Concomitant
Pulmonary Vein Stenosis Other Serious Female 1/4/2012 United States
Primary
Concomitant
Bladder Transitional Cell Carcinoma Disability 5/15/2011 67 Female 1/5/2012 Other Health Professional Italy
Primary
Concomitant
Fluid Retention Other Serious Female 104 lb 1/6/2012 United States
Primary
Concomitant
Pruritus Other Serious 1/5/2006 60 Female 139 lb 1/11/2012 Physician France
Primary
Concomitant
Neoplasm Malignant Hospitalization 8/1/2011 74 Female 110 lb 1/11/2012 Physician Germany
Primary
Secondary
Concomitant
Death Death 1/11/2012 85 Female 1/13/2012 United States
Primary
Concomitant
Ureteric Cancer Disability 5/15/2011 67 Female 1/13/2012 Other Health Professional Italy
Primary
Concomitant
Drug Intolerance Other Serious 6/1/2011 74 Female 1/30/2012 Physician Belgium
Primary
Concomitant
Nausea Other Serious 2/1/2011 70 Female 1/31/2012 Consumer Australia
Primary
Concomitant
Vomiting Hospitalization 1/16/2012 85 Female 142 lb 2/2/2012 United States
Primary
Concomitant
Cardiac Failure Congestive Other Serious 12/1/2011 60 Female 104 lb 2/2/2012 Consumer United States
Primary
Concomitant
Bladder Cancer Other Serious 5/15/2011 67 Female 2/3/2012 Other Health Professional Italy
Primary
Concomitant
Oedema Hospitalization 11/23/2011 60 Female 104 lb 2/20/2012 Other Health Professional United States
Primary
Concomitant
Skin Depigmentation Hospitalization 9/14/2006 59 Female 198 lb 2/24/2012 Consumer United States
Primary
Concomitant
Arthritis Other Serious Male 220 lb 3/6/2012 Physician Netherlands
Primary
Concomitant
Oropharyngeal Pain 3/4/2011 83 Female 3/9/2012 Consumer United States
Primary
Concomitant
Gingival Bleeding Death 8/1/2011 62 Female 215 lb 3/13/2012 Physician United States
Primary
Concomitant
Pericardial Effusion Life Threatening 49 Female 204 lb 7/8/2009 Physician United States
Primary
Concomitant
Oedema Peripheral Other Serious 7/1/2008 81 Female 100 lb 7/8/2009 Other Health Professional United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 11/23/2011 60 Female 104 lb 4/5/2012 Other Health Professional United States
Primary
Concomitant
Arthralgia Hospitalization 1/16/2010 63 Male 182 lb 5/28/2010 Physician United States
Primary
Concomitant
Drug Interaction Hospitalization 2/18/2010 86 Female 5/28/2010 Consumer United States
Primary
Concomitant
Blood Pressure Decreased Hospitalization 11/17/2008 72 Female 180 lb 7/8/2009 Pharmacist United States
Primary
Concomitant
Dyspnoea Other Serious 12/2/2008 63 Female 7/8/2009 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 11/17/2008 72 Female 180 lb 7/8/2009 Pharmacist United States
Primary
Concomitant
Generalised Oedema Life Threatening 49 Female 204 lb 7/8/2009 Physician United States
Primary
Concomitant
Swelling Face Other Serious 7/1/2008 81 Female 100 lb 7/8/2009 Other Health Professional United States
Primary
Concomitant
Nausea Hospitalization 11/23/2011 60 Female 104 lb 4/9/2012 Consumer United States
Primary
Concomitant
Blood Viscosity Increased Hospitalization 1/14/2010 82 Female 5/28/2010 Consumer United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 12/14/2009 60 Female 122 lb 5/28/2010 Other Health Professional United States
Primary
Concomitant
Neutropenia Other Serious 8/1/2008 3 Male 5/28/2010 Consumer United States
Primary
Concomitant
Nausea Other Serious 2/22/2012 69 Male 182 lb 4/20/2012 Physician United States
Primary
Concomitant
Neutropenia Other Serious 71 Female 5/28/2010 Physician United States
Primary
Concomitant
Rash Pruritic Disability 11/23/2009 74 Female 5/28/2010 Other Health Professional United States
Primary
Concomitant
Night Sweats Other Serious 10/1/2009 74 Female 220 lb 5/28/2010 Physician United States
Primary
Concomitant
Granulocytes Abnormal Other Serious 9/10/2009 58 Female 122 lb 5/28/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious Male 5/16/2011 Consumer United States
Primary
Concomitant
Diarrhoea Other Serious 1/1/2010 51 Female 4/30/2012 Consumer Argentina
Primary
Concomitant
Neuropathy Peripheral Other Serious 9/15/2010 5/16/2011 Physician United States
Primary
Concomitant
Diarrhoea Other Serious Female 5/3/2012 Consumer United States
Primary
Concomitant
Anaemia Other Serious 11/23/2011 60 Female 104 lb 5/4/2012 Other Health Professional United States
Primary
Concomitant
Death Death 4/24/2012 Male 5/4/2012 Consumer United States
Primary
Concomitant
Death Death 4/17/2012 88 Female 5/8/2012 Consumer United States
Primary
Concomitant
Thrombocytopenia Death 5/6/2012 74 Male 234 lb 5/25/2012 Consumer United States
Primary
Concomitant
Death Death 7/10/2012 56 Male 7/12/2012 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization Female 189 lb 7/16/2012 Physician United States
Primary
Concomitant
Myalgia Hospitalization 5/20/2012 55 Female 267 lb 7/20/2012 Other Health Professional United States
Primary
Concomitant
Nausea Death 1/25/2010 76 Male 381 lb 7/23/2012 Physician Germany
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 5/20/2012 55 Female 7/23/2012 Other Health Professional United States
Primary
Concomitant
Oedema Hospitalization 5/20/2012 55 Female 8/8/2012 Other Health Professional United States
Primary
Concomitant

Drug Data