Zoledronic Acid



Indications and Reactions:

Role Indications Reactions
Primary
Metastases To Bone 23.4%
Osteoporosis 19.7%
Multiple Myeloma 13.1%
Breast Cancer 12.8%
Osteoporosis Postmenopausal 6.4%
Prostate Cancer 5.1%
Osteoporotic Fracture 3.4%
Hypertension 3.1%
Breast Cancer Metastatic 2.3%
Analgesic Therapy 1.3%
Bone Sarcoma 1.3%
Pain 1.3%
Prophylaxis 1.2%
Osteolysis 1.1%
Osteitis Deformans 1.0%
Prostate Cancer Metastatic 0.9%
Lung Neoplasm Malignant 0.7%
Renal Cell Carcinoma 0.7%
Bone Lesion 0.6%
Osteopenia 0.6%
Osteonecrosis 21.8%
Tooth Extraction 16.5%
Osteonecrosis Of Jaw 14.7%
Death 8.2%
Pain 4.2%
Surgery 4.1%
Bone Disorder 3.6%
Pyrexia 3.6%
Vomiting 3.3%
Wound Closure 3.1%
Toothache 2.8%
Pain In Jaw 2.8%
Wound Dehiscence 2.5%
Tooth Loss 1.5%
Renal Impairment 1.3%
Swelling 1.3%
Fall 1.2%
Pain In Extremity 1.2%
Pneumonia 1.2%
Wound Debridement 1.1%
Secondary
Breast Cancer 16.3%
Multiple Myeloma 13.0%
Osteoporosis 11.9%
Metastases To Bone 9.7%
Product Used For Unknown Indication 9.0%
Drug Use For Unknown Indication 6.8%
Prostate Cancer 6.7%
Breast Cancer Metastatic 4.3%
Osteoporotic Fracture 3.8%
Hypertension 3.3%
Osteolysis 2.2%
Prophylaxis 2.0%
Pain 1.8%
Non-small Cell Lung Cancer Stage Iv 1.8%
Metastatic Renal Cell Carcinoma 1.7%
Prostate Cancer Metastatic 1.3%
Non-small Cell Lung Cancer 1.2%
Plasma Cell Myeloma 1.1%
Osteoporosis Postmenopausal 1.1%
Hypercalcaemia 1.0%
Osteonecrosis 25.8%
Osteonecrosis Of Jaw 20.0%
Tooth Extraction 7.0%
Vomiting 5.1%
Femur Fracture 4.9%
Pain 4.3%
Renal Failure Acute 4.3%
Pain In Jaw 3.7%
Surgery 3.1%
Urinary Tract Infection 2.9%
Weight Decreased 2.9%
Death 2.5%
Renal Impairment 2.5%
Pyrexia 2.0%
Osteomyelitis 1.8%
Toothache 1.6%
Upper Limb Fracture 1.6%
Neoplasm Malignant 1.4%
Respiratory Failure 1.4%
Pain In Extremity 1.2%
Concomitant
Product Used For Unknown Indication 14.3%
Drug Use For Unknown Indication 12.3%
Multiple Myeloma 11.5%
Prostate Cancer 9.8%
Prophylaxis 5.8%
Pain 5.5%
Hypertension 4.8%
Metastases To Bone 4.0%
Breast Cancer 3.7%
Prostate Cancer Metastatic 3.6%
Cancer Pain 3.3%
Breast Cancer Metastatic 3.3%
Nausea 2.9%
Plasma Cell Myeloma 2.9%
Constipation 2.7%
Osteoporosis 2.2%
Medical Diet 1.9%
Insomnia 1.8%
Premedication 1.8%
Prostate Cancer Stage Iv 1.8%
Thrombocytopenia 9.5%
Vomiting 8.2%
Sepsis 7.1%
Pyrexia 6.5%
Pneumonia 6.0%
Urinary Tract Infection 5.7%
Prostate Cancer 5.4%
Renal Failure Acute 5.2%
Drug Ineffective 4.9%
Pleural Effusion 4.6%
Weight Decreased 4.6%
Anaemia 4.4%
Death 4.4%
Renal Failure 4.4%
Osteonecrosis 3.5%
Respiratory Failure 3.3%
White Blood Cell Count Increased 3.3%
Multiple Myeloma 3.0%
Nausea 3.0%
Pulmonary Embolism 3.0%
Interacting
Breast Cancer 53.5%
Product Used For Unknown Indication 14.7%
Metastasis 8.1%
Drug Use For Unknown Indication 7.4%
Breast Cancer Metastatic 5.0%
Crohn's Disease 2.3%
Metastases To Bone 1.6%
Plasma Cell Myeloma 1.6%
Hypertension 1.2%
Osteoporosis 1.2%
Osteoporotic Fracture 1.2%
Metastatic Renal Cell Carcinoma 0.8%
Rheumatoid Arthritis 0.8%
Metastases To Pleura 0.4%
Pain 0.4%
Weight Decreased 38.2%
Osteonecrosis 26.5%
Mobility Decreased 8.8%
Cardio-respiratory Arrest 5.9%
Thrombocytopenia 5.9%
Gingival Recession 2.9%
Haemophilus Bacteraemia 2.9%
Leukopenia 2.9%
Osteonecrosis Of Jaw 2.9%
Septic Shock 2.9%