Calcium Carbonate combined with Zoledronic Acid

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pain In Jaw Hospitalization 3/1/2005 71 Male 12/15/2006 Denmark
Primary
Concomitant
Surgery Other Serious 1/1/1997 86 Female 287 lb 3/21/2007 Physician United States
Primary
Concomitant
Pain Other Serious 11/1/2005 48 4/6/2007 Spain
Primary
Concomitant
Pancreatitis Acute Hospitalization 10/6/2006 90 Female 123 lb 7/7/2007 Physician Poland
Primary
Concomitant
Pancreatitis Acute Hospitalization 10/6/2006 90 Female 123 lb 7/20/2007 Physician Poland
Primary
Concomitant
Urinary Tract Infection Hospitalization 6/22/2005 81 Male 200 lb 11/8/2007 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 8/19/2005 86 Female 143 lb 11/9/2007 Physician Argentina
Primary
Concomitant
Dizziness Hospitalization 9/12/2003 93 Female 104 lb 11/8/2007 Physician Denmark
Primary
Concomitant
Skin Ulcer Hospitalization 12/26/2005 56 180 lb 12/14/2007 Physician Argentina
Primary
Concomitant
Necrosis Hospitalization 3/16/2005 61 Female 151 lb 12/14/2007 Physician Austria
Primary
Concomitant
Prosthesis Implantation Hospitalization 12/30/2006 84 Female 12/15/2007 Physician Belgium
Primary
Concomitant
Toe Operation Hospitalization 8/27/2004 78 Female 172 lb 12/15/2007 Physician Belgium
Primary
Concomitant
Pain In Extremity Hospitalization 8/1/2004 68 Male 12/15/2007 Physician Belgium
Primary
Concomitant
Ischaemic Stroke Other Serious 7/19/2006 80 Male 143 lb 12/17/2007 Physician Czech Republic
Primary
Concomitant
Myocardial Infarction Hospitalization 5/29/2006 74 Female 214 lb 12/17/2007 Physician Czech Republic
Primary
Concomitant
Ventricular Arrhythmia Death 1/29/2006 78 Female 154 lb 12/17/2007 Physician Czech Republic
Primary
Concomitant
Therapeutic Procedure Other Serious 5/18/2004 61 Female 161 lb 12/18/2007 Physician Denmark
Primary
Concomitant
Osteosynthesis Hospitalization 4/20/2003 88 Female 129 lb 12/18/2007 Physician Denmark
Primary
Concomitant
Osteonecrosis Hospitalization 5/1/2005 84 Female 91 lb 12/18/2007 Physician Denmark
Primary
Concomitant
Osteonecrosis Hospitalization 11/11/2005 55 Female 152 lb 12/17/2007 Physician Czech Republic
Primary
Concomitant
Neuralgia Hospitalization 8/1/2006 80 Male 197 lb 12/18/2007 Physician Denmark
Primary
Concomitant
Respiratory Failure Hospitalization 6/14/2006 65 Female 104 lb 12/18/2007 Physician Denmark
Primary
Concomitant
Pneumonia Other Serious 9/18/2006 72 Male 12/18/2007 Physician Denmark
Primary
Concomitant
Skin Neoplasm Excision Other Serious 11/20/2006 81 Male 157 lb 12/18/2007 Physician Denmark
Primary
Concomitant
Wound Infection Hospitalization 12/1/2006 51 Male 216 lb 12/19/2007 Physician Finland
Primary
Concomitant
Osteoporosis Hospitalization 2/2/2005 68 Female 117 lb 12/20/2007 Physician Russian Federation
Primary
Concomitant
Mental Status Changes Hospitalization 7/30/2006 67 Female 126 lb 12/20/2007 Physician Canada
Primary
Concomitant
Pneumonia Hospitalization 4/25/2006 77 Female 144 lb 12/20/2007 Physician Canada
Primary
Concomitant
Surgery Hospitalization 12/6/2004 66 Female 139 lb 12/20/2007 Physician Sweden
Primary
Concomitant
Osteonecrosis Hospitalization 8/1/2004 82 Female 96 lb 12/20/2007 Physician United Kingdom
Primary
Concomitant
Pain Hospitalization 12/8/2004 62 Male 12/20/2007 Physician Sweden
Primary
Concomitant
Osteonecrosis Hospitalization 4/11/2004 68 Female 104 lb 12/20/2007 Physician Switzerland
Primary
Concomitant
Osteonecrosis Hospitalization 12/31/2004 69 Female 128 lb 12/20/2007 Physician Sweden
Primary
Concomitant
General Physical Health Deterioration Hospitalization 3/1/2006 85 Female 110 lb 12/20/2007 Physician Norway
Primary
Concomitant
Surgery Other Serious 10/20/2005 60 Female 146 lb 12/20/2007 Physician Norway
Primary
Concomitant
Skin Neoplasm Excision Other Serious 9/11/2006 76 Male 163 lb 12/21/2007 Physician Sweden
Primary
Concomitant
General Physical Health Deterioration Death 3/1/2006 84 Male 134 lb 12/21/2007 Physician Turkey
Primary
Concomitant
Meningioma Benign Hospitalization 10/1/2006 Male 168 lb 12/21/2007 Physician Norway
Primary
Concomitant
Pancreatitis Acute Hospitalization 10/6/2006 90 Female 123 lb 12/21/2007 Physician Poland
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/29/2003 75 Female 132 lb 12/21/2007 Physician United States
Primary
Concomitant
Osteomyelitis Hospitalization 9/1/2003 84 Male 198 lb 12/21/2007 Physician United States
Primary
Concomitant
Osteomyelitis Hospitalization 9/1/2003 84 Male 198 lb 12/21/2007 Physician United States
Primary
Concomitant
Osteomyelitis Hospitalization 8/22/2005 84 Male 240 lb 12/22/2007 Physician United States
Primary
Concomitant
Thrombocytopenia Life Threatening 10/2/2002 81 Male 140 lb 1/3/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/28/2004 63 Male 381 lb 1/3/2008 Physician United States
Primary
Concomitant
Pubic Rami Fracture Hospitalization 9/16/2004 83 Female 130 lb 1/3/2008 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 1/1/2005 79 Male 1/3/2008 Physician United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 2/2/2004 83 Female 130 lb 1/9/2008 Physician United States
Primary
Concomitant
Vitamin D Deficiency Other Serious 60 Male 9/19/2008 Other Health Professional Australia
Primary
Concomitant
Hypocalcaemia Other Serious 1/11/2008 Male 2/13/2009 Physician Japan
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 12/14/2007 Male 3/30/2009 Physician Japan
Primary
Concomitant
Muscle Spasms Other Serious 57 Female 4/6/2009 Other Health Professional Turkey
Primary
Concomitant
Osteonecrosis Other Serious 12/14/2007 Male 88 lb 6/30/2009 Other Health Professional Japan
Primary
Concomitant
Osteonecrosis Other Serious 12/14/2007 Male 88 lb 10/29/2009 Other Health Professional Japan
Primary
Concomitant
Gastric Ulcer Hospitalization 11/8/2009 90 Male 128 lb 12/30/2009 Physician Slovakia (Slovak Republic)
Primary
Secondary
Concomitant
Gastric Ulcer Hospitalization 11/8/2009 90 Male 128 lb 1/18/2010 Physician Slovakia (Slovak Republic)
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 6/14/2006 Female 3/8/2010 Physician Belgium
Primary
Secondary
Concomitant
Pulmonary Hypertension Life Threatening 12/18/2009 Female 3/19/2010 Physician United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 1/25/2009 Male 3/26/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Venous Insufficiency Hospitalization 3/17/2010 47 Female 3/31/2010 Other Health Professional Jordan
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 69 Female 4/23/2010 Physician United States
Primary
Concomitant
Wound Complication Hospitalization 1/6/2010 55 Female 5/6/2010 Physician Hong Kong
Primary
Secondary
Concomitant
Prosthesis User Other Serious 10/1/2007 71 Female 5/10/2010 Other Health Professional Argentina
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/18/2008 53 Female 187 lb 5/13/2010 Other Health Professional Greece
Primary
Concomitant
Pleural Effusion 2/16/2009 60 Female 181 lb 6/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Other Serious 10/30/2008 53 Male 6/24/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Multi-organ Failure Other Serious 5/19/2010 68 Female 189 lb 7/1/2010 Physician United States
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 69 Female 7/1/2010 Physician United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 1/25/2009 77 Male 7/8/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 7/1/2008 69 Female 7/19/2010 Consumer United States
Primary
Concomitant
Swelling Other Serious 8/26/2010 50 Female 106 lb 10/1/2010 Physician Australia
Primary
Concomitant
Rectal Haemorrhage Hospitalization 1/25/2009 77 Male 11/1/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Acute Abdomen Life Threatening 12/18/2010 72 Male 139 lb 12/31/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Death 7/1/2008 69 Female 1/24/2011 Physician United States
Primary
Concomitant
Acute Myocardial Infarction Hospitalization 12/18/2010 72 Male 139 lb 3/27/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/17/2011 Male 214 lb 5/16/2011 Physician United States
Primary
Concomitant
Rib Fracture Other Serious 12/20/2010 61 154 lb 5/19/2011 Physician Canada
Primary
Concomitant
Eyelid Margin Crusting Other Serious 11/1/2010 44 Female 5/19/2011 Physician Belgium
Primary
Concomitant
Abdominal Distension Hospitalization 3/17/2011 Male 214 lb 5/19/2011 Physician United States
Primary
Concomitant
Hypercholesterolaemia Other Serious 8/13/2008 Female 185 lb 5/20/2011 Physician France
Primary
Secondary
Chills Other Serious 4/4/2011 74 Female 5/20/2011 Physician Belgium
Primary
Concomitant
Myocardial Infarction Death 5/14/2011 83 Male 187 lb 5/24/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Skeletal Injury Other Serious 8/1/2010 59 Female 5/26/2011 Consumer Canada
Primary
Concomitant
Tardive Dyskinesia Other Serious 80 Female 5/31/2011 Other Health Professional Germany
Primary
Concomitant
Hip Fracture Other Serious 84 Male 5/31/2011 Other Health Professional Germany
Primary
Concomitant
Loss Of Consciousness Hospitalization 5/31/2011 Other Health Professional Germany
Primary
Concomitant
Bone Density Abnormal Hospitalization 12/6/2010 76 Female 159 lb 5/31/2011 Canada
Primary
Concomitant
Hip Fracture Other Serious 12/10/2010 83 Female 6/1/2011 Physician Canada
Primary
Concomitant
Rash Hospitalization 12/30/2010 75 Female 152 lb 6/1/2011 Physician United States
Primary
Concomitant
Rectal Perforation Life Threatening 12/18/2010 72 Male 132 lb 6/2/2011 Physician Germany
Primary
Secondary
Concomitant
Monocyte Count Increased Hospitalization 5/4/2011 85 Male 6/2/2011 Physician Hungary
Primary
Concomitant
Pain Death 5/30/2011 73 Male 6/3/2011 Physician China
Primary
Concomitant
Osteonecrosis Of Jaw Disability 6/1/2009 47 Female 6/7/2011 Physician Germany
Primary
Concomitant
Neoplasm Malignant Hospitalization 6/22/2010 Female 170 lb 6/7/2011 Physician Germany
Primary
Concomitant
Gout Other Serious 7/4/2004 64 Male 6/7/2011 Physician Canada
Primary
Concomitant
General Physical Health Deterioration Other Serious Female 165 lb 6/8/2011 Physician Canada
Primary
Concomitant
Arrhythmia Other Serious 3/27/2010 72 Female 6/8/2011 Physician Canada
Primary
Concomitant
Myocardial Infarction Death 5/14/2011 83 Male 187 lb 6/8/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 8/14/2008 64 Female 6/4/2011 Physician Sweden
Primary
Concomitant
Decreased Appetite Death 11/1/2003 67 Male 6/6/2011 Physician Belgium
Primary
Concomitant
Kidney Infection Hospitalization 55 Female 6/9/2011 Consumer South Africa
Primary
Concomitant
Hypocalcaemia Hospitalization 8/31/2006 67 Male 152 lb 6/8/2011 Physician Mexico
Primary
Concomitant
Sepsis Other Serious 6/20/2003 61 Male 6/11/2011 Physician Spain
Primary
Concomitant
Arthralgia Hospitalization 8/12/2005 64 Male 6/11/2011 Physician United Kingdom
Primary
Concomitant
Tumour Associated Fever Hospitalization 7/22/2006 84 Male 132 lb 6/11/2011 Physician Taiwan, Province Of China
Primary
Concomitant
Bladder Obstruction Hospitalization 5/6/2006 64 Male 192 lb 6/11/2011 Physician Germany
Primary
Secondary
Hypertensive Crisis Hospitalization 7/24/2008 Female 127 lb 6/11/2011 Physician Germany
Primary
Concomitant
Macular Degeneration Other Serious 8/1/2010 78 Female 6/15/2011 Consumer Canada
Primary
Concomitant
Myocardial Infarction Other Serious 5/15/2011 83 Female 6/16/2011 Canada
Primary
Concomitant
Death Death 1/1/2010 75 Female 6/17/2011 Consumer Malaysia
Primary
Concomitant
Spinal Compression Fracture Other Serious 1/15/2011 63 Female 6/20/2011 Consumer Canada
Primary
Concomitant
Bruxism Other Serious 1/1/2010 79 Female 6/20/2011 Physician Canada
Primary
Concomitant
Hydronephrosis Hospitalization Female 6/20/2011 Physician Norway
Primary
Concomitant
Osteonecrosis Of Jaw Hospitalization 8/5/2010 68 Male 168 lb 6/20/2011 United States
Primary
Concomitant
Muscle Spasms Other Serious Female 165 lb 6/21/2011 Canada
Primary
Concomitant
Fall Other Serious 3/27/2010 72 Female 6/22/2011 Consumer Canada
Primary
Concomitant
Pyrexia Death 5/30/2011 73 Male 6/24/2011 Physician China
Primary
Concomitant
Abscess Intestinal Hospitalization 10/25/2010 67 Female 101 lb 6/28/2011 Other Health Professional Canada
Primary
Concomitant
Myocardial Infarction Death 5/14/2011 83 Male 187 lb 6/28/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Nausea Other Serious 88 Male 121 lb 6/29/2011 Consumer China
Primary
Concomitant
Hypertension Other Serious Female 6/30/2011 Physician Canada
Primary
Concomitant
Syncope Other Serious 3/4/2010 78 Female 6/30/2011 Physician Germany
Primary
Concomitant
Lower Limb Fracture Other Serious Female 106 lb 7/1/2011 Physician Canada
Primary
Concomitant
Drug Ineffective Other Serious 11/30/2010 Female 150 lb 7/4/2011 Physician Germany
Primary
Concomitant
Dizziness Disability 12/3/2009 Female 117 lb 7/4/2011 Physician Germany
Primary
Concomitant
Blood Pressure Abnormal Other Serious 3/27/2010 72 Female 7/5/2011 Consumer Canada
Primary
Concomitant
Hypersensitivity Other Serious 6/24/2011 64 Female 207 lb 7/8/2011 Other Health Professional Canada
Primary
Concomitant
Nausea Other Serious 3/4/2011 64 Male 155 lb 7/12/2011 Physician Canada
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Other Serious 2/9/2010 59 Female 229 lb 7/19/2011 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 6/10/2011 74 Male 8/1/2011 Physician Australia
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/10/2011 74 Male 8/11/2011 Physician Australia
Primary
Secondary
Concomitant
Hallucination Hospitalization 3/1/2010 73 Female 154 lb 8/17/2011 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/10/2011 74 Male 8/19/2011 Physician Australia
Primary
Secondary
Concomitant
Hypercalcaemia Death 10/7/2008 77 Male 121 lb 8/12/2011 Physician Hungary
Primary
Concomitant
Pain Other Serious 3/1/2010 73 Female 154 lb 9/1/2011 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 8/20/2011 79 Male 9/2/2011 Physician Australia
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 12/30/2010 75 Female 152 lb 9/9/2011 Physician United States
Primary
Concomitant
Sepsis Hospitalization 6/10/2011 74 Male 9/15/2011 Physician Australia
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 8/20/2011 79 Male 9/19/2011 Physician Australia
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 8/20/2011 79 Male 9/21/2011 Physician Australia
Primary
Secondary
Concomitant
Micturition Urgency Hospitalization 3/1/2010 73 Female 154 lb 9/22/2011 Physician United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Other Serious 1/29/2010 63 Female 232 lb 9/22/2011 Physician United States
Primary
Concomitant
Tumour Pain Hospitalization 5/22/2009 74 Female 187 lb 9/23/2011 Physician Spain
Primary
Secondary
Concomitant
Pancreatitis Life Threatening 60 Female 174 lb 10/3/2011 Other Health Professional United Kingdom
Primary
Concomitant
Somnolence Hospitalization 63 Male 10/7/2011 Physician United States
Primary
Concomitant
Arthralgia 6/7/2010 70 Female 194 lb 10/18/2011 Consumer United States
Primary
Secondary
Concomitant
Psychotic Disorder Hospitalization 8/13/2011 68 Male 1/10/2012 Other Health Professional Spain
Primary
Secondary
Concomitant
Haemolytic Uraemic Syndrome Hospitalization 63 Male 1/23/2012 Other Health Professional
Primary
Concomitant
Gastric Ulcer Hospitalization 11/8/2009 90 Male 128 lb 1/30/2012 Physician Slovakia (Slovak Republic)
Primary
Secondary
Concomitant
Haematuria Hospitalization 12/7/2009 63 Male 183 lb 1/31/2012 Physician France
Primary
Secondary
Concomitant

Drug Data