Docetaxel combined with Zoledronic Acid

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Osteonecrosis Other Serious 63 Male 3/10/2006 Other Health Professional United States
Primary
Concomitant
Sinus Tachycardia Hospitalization 6/26/2004 53 Female 206 lb 5/19/2006 Physician United States
Primary
Secondary
Concomitant
Cardiac Arrest Death 7/3/2006 62 Male 181 lb 7/18/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 7/17/2006 54 Male 181 lb 8/7/2006 Other Health Professional United Kingdom
Primary
Secondary
Aortic Aneurysm Rupture Death 7/3/2006 62 Male 181 lb 8/25/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sequestrectomy Other Serious 72 Female 9/19/2006 Other Health Professional Italy
Primary
Concomitant
Vomiting Hospitalization 9/30/2006 67 Male 187 lb 10/26/2006 Other Health Professional United Kingdom
Primary
Secondary
Vomiting Hospitalization 9/30/2006 67 Male 187 lb 11/9/2006 Other Health Professional United Kingdom
Primary
Secondary
Weight Increased Other Serious 1/1/2006 43 Female 11/9/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/6/2007 75 Male 185 lb 2/1/2007 Other Health Professional United Kingdom
Primary
Secondary
Osteonecrosis Other Serious 1/1/2006 Female 126 lb 2/20/2007 Physician Germany
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 1/1/2006 Female 126 lb 2/20/2007 Physician Germany
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 1/1/2006 Female 126 lb 2/20/2007 Physician Germany
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 1/1/2006 Female 126 lb 2/28/2007 Physician Germany
Primary
Secondary
Concomitant
Subdural Haematoma Life Threatening 1/2/2007 73 Male 139 lb 2/28/2007 Other Health Professional United Kingdom
Primary
Secondary
Malaise Other Serious 1/18/2007 46 Female 117 lb 3/29/2007 Physician France
Primary
Concomitant
Tooth Extraction Other Serious 6/1/2006 42 Female 125 lb 4/17/2007 United Kingdom
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2006 Female 126 lb 6/1/2007 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 3/27/2006 75 Male 120 lb 6/28/2007 Physician Mexico
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2006 Female 126 lb 7/27/2007 Physician Germany
Primary
Secondary
Concomitant
Swelling Other Serious 12/1/2005 60 Male 9/15/2007 Other Health Professional Spain
Primary
Concomitant
Tooth Loss Other Serious 68 Male 9/15/2007 Other Health Professional Spain
Primary
Concomitant
Tooth Loss Other Serious 70 Male 9/15/2007 Other Health Professional Spain
Primary
Concomitant
Tooth Infection Other Serious 10/1/2005 75 Male 9/24/2007 Physician United States
Primary
Concomitant
Thrombosis Hospitalization 10/6/2007 55 Male 163 lb 2/5/2008 Other Health Professional United Kingdom
Primary
Secondary
Neutropenic Infection Hospitalization 1/14/2008 76 Male 146 lb 2/6/2008 Other Health Professional United Kingdom
Primary
Secondary
Blood Urea Increased Hospitalization 11/30/2007 65 Male 2/8/2008 Physician Greece
Primary
Concomitant
Renal Failure Other Serious 2/18/2008 59 Male 3/11/2008 Other Health Professional United Kingdom
Primary
Secondary
Pericardial Effusion Other Serious 50 Female 4/18/2008 Pharmacist United Kingdom
Primary
Concomitant
Sepsis Hospitalization 12/22/2007 Female 209 lb 4/25/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Tooth Abscess Other Serious 7/1/2005 64 Male 4/29/2008 Other Health Professional Italy
Primary
Concomitant
Tooth Extraction Other Serious 74 Male 4/30/2008 Other Health Professional Spain
Primary
Concomitant
Pyrexia Hospitalization 12/22/2007 Female 209 lb 5/23/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Hospitalization 5/25/2008 70 Male 163 lb 6/5/2008 Other Health Professional United Kingdom
Primary
Secondary
White Blood Cell Count Increased Hospitalization 12/22/2007 Female 209 lb 6/5/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 5/25/2008 70 Male 163 lb 6/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Osteonecrosis Other Serious 74 Male 7/21/2008 Other Health Professional Spain
Primary
Concomitant
Renal Impairment Other Serious 74 Male 8/6/2008 Other Health Professional Spain
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 70 Male 8/15/2008 Other Health Professional Germany
Primary
Concomitant
Osteonecrosis Other Serious 58 Male 8/15/2008 Other Health Professional Germany
Primary
Concomitant
Tooth Extraction Other Serious 63 Male 8/15/2008 Other Health Professional Germany
Primary
Concomitant
Tooth Extraction Other Serious 66 Male 8/15/2008 Other Health Professional Germany
Primary
Concomitant
Tooth Extraction Other Serious 64 Male 8/15/2008 Other Health Professional Germany
Primary
Concomitant
Tooth Extraction Other Serious 61 8/15/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 68 Male 8/15/2008 Other Health Professional Germany
Primary
Concomitant
Tooth Extraction Other Serious 58 Male 8/15/2008 Other Health Professional Germany
Primary
Concomitant
Prostate Cancer Death 1/19/2008 76 Male 8/19/2008 Japan
Primary
Secondary
Concomitant
Prostate Cancer Death 1/19/2008 76 Male 9/4/2008 Japan
Primary
Secondary
Concomitant
Pain Hospitalization 78 Female 9/8/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Prostate Cancer Life Threatening 1/19/2008 76 Male 9/18/2008 Japan
Primary
Secondary
Concomitant
General Physical Health Deterioration Other Serious 2/8/2008 60 Female 127 lb 9/18/2008 Japan
Primary
Concomitant
Prostate Cancer Life Threatening 1/19/2008 76 Male 10/8/2008 Japan
Primary
Secondary
Concomitant
Nausea Other Serious 1/5/2007 61 Male 10/10/2008 Japan
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 11/23/2008 72 Male 203 lb 12/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Peptic Ulcer Haemorrhage Death 11/21/2008 73 Male 168 lb 12/9/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypotension Hospitalization 10/22/2008 Male 12/23/2008 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 11/1/2008 73 Male 12/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Tooth Infection Hospitalization 12/14/2008 Male 123 lb 12/23/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 11/23/2008 72 Male 203 lb 12/30/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 74 Male 1/12/2009 Other Health Professional Germany
Primary
Secondary
Osteonecrosis Other Serious 76 Male 1/12/2009 Other Health Professional Germany
Primary
Secondary
Tooth Infection Hospitalization 12/14/2008 Male 123 lb 1/14/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 11/23/2008 72 Male 203 lb 1/16/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Musculoskeletal Pain Hospitalization 7/13/2007 Female 165 lb 1/23/2009 Physician Germany
Primary
Concomitant
Interacting
Prostatic Specific Antigen Increased 1/1/2007 Male 168 lb 1/27/2009 Physician United States
Primary
Concomitant
Tooth Extraction Other Serious 66 Male 1/28/2009 Other Health Professional Germany
Primary
Concomitant
Tooth Extraction Other Serious 61 1/28/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 58 Male 1/28/2009 Other Health Professional Germany
Primary
Concomitant
Osteonecrosis Other Serious 58 Male 1/28/2009 Other Health Professional Germany
Primary
Concomitant
Tooth Extraction Other Serious 63 Male 1/28/2009 Other Health Professional Germany
Primary
Concomitant
Tooth Extraction Other Serious 70 Male 1/28/2009 Other Health Professional Germany
Primary
Concomitant
Tooth Extraction Other Serious 64 Male 1/28/2009 Other Health Professional Germany
Primary
Concomitant
Tooth Extraction Other Serious 68 Male 1/28/2009 Other Health Professional Germany
Primary
Concomitant
Urinary Retention Hospitalization 11/23/2008 72 Male 203 lb 2/3/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/28/2009 Male 4 lb 2/5/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/28/2009 60 Male 220 lb 2/9/2009 Other Health Professional United Kingdom
Primary
Secondary
Vomiting Hospitalization 2/7/2009 68 Male 196 lb 2/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Swelling Other Serious 1/12/2009 Male 124 lb 2/20/2009 Physician Thailand
Primary
Concomitant
Vomiting Hospitalization 1/28/2009 Male 4 lb 2/26/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 10/22/2008 Male 3/9/2009 Physician United States
Primary
Concomitant
Neutropenic Infection Hospitalization 2/18/2009 83 Male 187 lb 3/12/2009 Other Health Professional United Kingdom
Primary
Secondary
Myalgia Other Serious 1/29/2008 Male 3/14/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 58 Male 3/31/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Neutropenia Hospitalization 11/25/2008 4/9/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/28/2009 60 Male 220 lb 4/29/2009 Other Health Professional United Kingdom
Primary
Secondary
Soft Tissue Disorder Disability 2/20/2008 Male 4/29/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Nausea Hospitalization 2/27/2009 Male 4/29/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 12/13/2008 Male 223 lb 4/30/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Neutropenia Hospitalization 11/25/2008 5/7/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Nausea Hospitalization 2/27/2009 Male 5/8/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Nausea Hospitalization 2/27/2009 Male 5/19/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2006 Female 126 lb 5/19/2009 Physician Germany
Primary
Secondary
Concomitant
Foot Operation Hospitalization 4/4/2009 Female 141 lb 6/3/2009 Physician Germany
Primary
Concomitant
Respiratory Tract Haemorrhage Life Threatening 5/17/2009 63 Male 157 lb 6/12/2009 Other Health Professional United Kingdom
Primary
Secondary
Neutropenia Hospitalization 11/25/2008 64 6/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 75 Male 7/8/2009 Other Health Professional Italy
Primary
Concomitant
Osteonecrosis Other Serious 68 Male 7/8/2009 Other Health Professional Italy
Primary
Concomitant
Thrombotic Microangiopathy Hospitalization Male 185 lb 7/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Soft Tissue Disorder Disability 2/20/2008 Male 7/15/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Blood Glucose Increased 3/1/2009 70 Male 7/22/2009 Consumer United States
Primary
Secondary
Concomitant
Blood Glucose Increased 3/1/2009 70 Male 7/22/2009 Consumer United States
Primary
Secondary
Concomitant
Troponin Increased Hospitalization 7/27/2009 57 Male 201 lb 8/14/2009 Other Health Professional France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/27/2009 74 Male 212 lb 8/31/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Diabetes Mellitus Other Serious 7/14/2009 61 Male 200 lb 9/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 6/15/2007 Female 131 lb 10/8/2009 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 9/21/2009 10/9/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Blood Glucose Increased 3/1/2009 70 Male 11/25/2009 Consumer United States
Primary
Secondary
Concomitant
Pyrexia Life Threatening 11/20/2009 Male 187 lb 12/24/2009 United States
Primary
Secondary
Concomitant
Pyrexia Life Threatening 11/20/2009 Male 185 lb 1/8/2010 United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 10/22/2008 Male 1/27/2010 Physician United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 1/16/2010 61 Male 2/4/2010 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 10/22/2008 Male 2/5/2010 Physician United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 1/16/2010 61 Male 2/25/2010 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Hypertension Life Threatening 12/18/2009 Female 3/19/2010 Physician United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 48 Female 3/23/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Venous Pressure Jugular Increased Hospitalization 12/15/2008 Male 3/29/2010 Physician Ireland
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/27/2009 74 Male 211 lb 3/23/2010 Physician United States
Primary
Secondary
Concomitant
Aspiration Death 5/12/2010 Pharmacist United States
Primary
Secondary
Concomitant
Myocardial Infarction Death 5/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious Male 5/12/2010 United States
Primary
Secondary
Concomitant
Hypocalcaemia Hospitalization 4/16/2010 41 Male 5/27/2010 Physician India
Primary
Secondary
Concomitant
Haematuria Other Serious 73 Male 8/2/2010 Other Health Professional Nigeria
Primary
Concomitant
Pyrexia Life Threatening 11/20/2009 64 Male 187 lb 8/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Life Threatening 11/20/2009 64 Male 187 lb 10/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 10/22/2008 74 Male 11/1/2010 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization Male 12/29/2010 Germany
Primary
Concomitant
Cardiovascular Disorder Hospitalization 12/6/2010 60 Female 150 lb 1/3/2011 Physician Germany
Primary
Secondary
Cardiovascular Disorder Hospitalization 12/6/2010 60 Female 150 lb 1/11/2011 Physician Germany
Primary
Secondary
Febrile Neutropenia Hospitalization 1/15/2010 61 Male 1/11/2011 Physician United States
Primary
Secondary
Concomitant
Nausea Hospitalization 1/1/2010 92 Male 159 lb 1/28/2011 Other Health Professional United States
Primary
Concomitant
Dyspnoea Hospitalization 12/6/2010 60 Female 150 lb 2/17/2011 Physician Germany
Primary
Secondary
Osteonecrosis Of Jaw Other Serious 1/3/2011 57 Male 222 lb 2/22/2011 Other Health Professional United States
Primary
Secondary
Gingival Infection Other Serious 1/3/2011 57 Male 220 lb 3/4/2011 Other Health Professional United States
Primary
Secondary
Diarrhoea Male 4/5/2011 Pharmacist United States
Primary
Concomitant
Cerebral Ischaemia Other Serious 3/4/2011 64 Male 155 lb 4/8/2011 Physician Canada
Primary
Secondary
Concomitant
Cerebral Infarction Death Female 4/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 2/16/2010 73 Male 178 lb 4/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 6/1/2010 56 Male 174 lb 4/19/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Intestinal Functional Disorder Other Serious 27 Female 5/1/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Ischaemia Other Serious Female 5/6/2011 Other Health Professional United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 4/19/2011 79 Male 148 lb 5/10/2011 Physician Denmark
Primary
Secondary
Concomitant
Myocardial Infarction Death 5/14/2011 83 Male 187 lb 5/24/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Other Serious 5/16/2011 68 Male 205 lb 6/2/2011 Other Health Professional United States
Primary
Secondary
Abscess Jaw Hospitalization 5/11/2011 73 Male 183 lb 6/7/2011 Physician United Kingdom
Primary
Concomitant
Myocardial Infarction Death 5/14/2011 83 Male 187 lb 6/8/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Other Serious 3/15/2010 Male 6/20/2011 Consumer United States
Primary
Secondary
Concomitant
Abscess Jaw Hospitalization 5/11/2011 73 Male 183 lb 6/21/2011 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/22/2011 75 Female 126 lb 6/27/2011 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Death 5/14/2011 83 Male 187 lb 6/28/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Anaemia Hospitalization 4/22/2011 75 Female 126 lb 7/6/2011 Consumer United States
Primary
Secondary
Concomitant

Drug Data