Pamidronate Disodium combined with Zoledronic Acid

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Wound Debridement Other Serious 67 Female 1/10/2006 Italy
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 55 1/10/2006 Italy
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 61 Male 3/9/2006 Other Health Professional United States
Primary
Secondary
Tooth Extraction Other Serious 3/1/2004 65 Male 4/4/2006 Other Health Professional Italy
Primary
Secondary
Sequestrectomy Other Serious 75 Female 4/12/2006 Switzerland
Primary
Secondary
Tooth Extraction Other Serious 8/1/2005 84 Female 6/8/2006 Other Health Professional New Zealand
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 77 Male 9/19/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Death Death 54 Male 9/19/2006 United States
Primary
Concomitant
Osteonecrosis Other Serious 75 Female 11/21/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 65 Female 11/21/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 65 Female 11/21/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Pain In Jaw Other Serious 75 Female 12/7/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Ulcer Other Serious 65 Female 12/7/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Ulcer Other Serious 65 Female 12/7/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 58 Female 1/25/2007 Other Health Professional United States
Primary
Secondary
Osteonecrosis Other Serious 73 Male 2/2/2007 Other Health Professional New Zealand
Primary
Secondary
Concomitant
Tooth Extraction Other Serious Female 2/3/2007 United Kingdom
Primary
Secondary
Pain Other Serious Female 3/1/2007 Other Health Professional United Kingdom
Primary
Secondary
No Therapeutic Response Hospitalization 4/26/2006 65 Male 176 lb 3/20/2007 Physician United States
Primary
Secondary
Concomitant
Gingival Pain Hospitalization 4/26/2006 65 Male 176 lb 4/16/2007 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 72 Female 6/5/2007 Other Health Professional Italy
Primary
Secondary
Osteonecrosis Other Serious 69 Female 6/5/2007 Other Health Professional Italy
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 58 Female 6/5/2007 Other Health Professional Italy
Primary
Secondary
Concomitant
Renal Impairment Other Serious 2/1/2006 76 Male 6/20/2007 Other Health Professional Finland
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 63 Male 7/10/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 56 Male 7/25/2007 Other Health Professional Turkey
Primary
Secondary
Wound Debridement Other Serious 45 Female 7/25/2007 Other Health Professional Turkey
Primary
Secondary
Osteonecrosis Other Serious 61 Female 9/5/2007 Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 51 Female 9/7/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Toothache Other Serious 2/1/2006 61 Female 9/14/2007 Japan
Primary
Secondary
Concomitant
Trismus Other Serious 57 Male 10/12/2007 Other Health Professional Italy
Primary
Secondary
Concomitant
Tooth Extraction Other Serious Male 10/25/2007 Other Health Professional Finland
Primary
Secondary
Osteonecrosis Other Serious 10/26/2007 Other Health Professional Greece
Primary
Secondary
Osteonecrosis Other Serious 10/26/2007 Other Health Professional Greece
Primary
Secondary
Osteonecrosis Other Serious 10/26/2007 Other Health Professional Greece
Primary
Secondary
Osteonecrosis Other Serious 10/30/2007 Other Health Professional Greece
Primary
Secondary
Osteonecrosis Other Serious 10/30/2007 Other Health Professional Greece
Primary
Secondary
Osteonecrosis Other Serious 10/30/2007 Other Health Professional Greece
Primary
Secondary
Osteonecrosis Other Serious 12/25/2007 Other Health Professional France
Primary
Secondary
Osteonecrosis Other Serious 12/25/2007 Other Health Professional France
Primary
Secondary
Osteonecrosis Other Serious 12/25/2007 Other Health Professional France
Primary
Secondary
Osteonecrosis Other Serious 12/25/2007 Other Health Professional France
Primary
Secondary
X-ray Abnormal Other Serious 11/1/2006 70 Female 2/1/2008 Japan
Primary
Secondary
Concomitant
Tenderness Required Intervention 12/4/2007 82 Male 211 lb 1/21/2008 Pharmacist United States
Primary
Secondary
Osteonecrosis Other Serious 51 Female 2/8/2008 United Kingdom
Primary
Concomitant
Interacting
Weight Decreased Other Serious 51 Female 2/21/2008 Other Health Professional United Kingdom
Primary
Secondary
Wound Treatment Other Serious 72 Female 2/26/2008 Other Health Professional Germany
Primary
Secondary
Wound Treatment Other Serious 57 Female 2/26/2008 Other Health Professional Germany
Primary
Secondary
Wound Treatment Other Serious 57 Female 2/26/2008 Other Health Professional Germany
Primary
Secondary
Wound Treatment Other Serious 65 Female 2/26/2008 Other Health Professional Germany
Primary
Secondary
Osteonecrosis Other Serious 51 Female 3/5/2008 United Kingdom
Primary
Concomitant
Interacting
Weight Decreased Other Serious 51 Female 3/14/2008 Other Health Professional United Kingdom
Primary
Secondary
Osteonecrosis Other Serious 51 Female 3/14/2008 United Kingdom
Primary
Concomitant
Interacting
Swelling Face Other Serious 3/1/2006 76 Female 3/27/2008 Other Health Professional Italy
Primary
Secondary
Tooth Fracture Other Serious 65 Female 4/7/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 56 Female 4/11/2008 Other Health Professional Canada
Primary
Secondary
Weight Decreased Other Serious 51 Female 4/15/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 55 Female 4/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 67 Male 4/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 69 Male 4/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 71 Male 4/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Sequestrectomy Other Serious 9/1/2004 58 Female 4/29/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 6/1/2004 Female 5/9/2008 Physician Australia
Primary
Secondary
Tooth Extraction Other Serious 6/1/2004 Female 5/9/2008 Physician Australia
Primary
Secondary
Osteonecrosis Other Serious 89 Female 7/1/2008 Italy
Primary
Secondary
Osteonecrosis Other Serious 83 Female 7/1/2008 Italy
Primary
Secondary
Surgery Other Serious 80 Female 7/1/2008 Italy
Primary
Secondary
Osteonecrosis Other Serious 82 Female 7/1/2008 Italy
Primary
Secondary
Osteonecrosis Other Serious 67 Male 7/1/2008 Italy
Primary
Secondary
Surgery Other Serious 59 Female 7/1/2008 Italy
Primary
Secondary
Osteonecrosis Other Serious 60 Female 7/1/2008 Italy
Primary
Secondary
Osteonecrosis Other Serious Female 7/1/2008 Italy
Primary
Secondary
Osteonecrosis Other Serious 78 Female 7/1/2008 Italy
Primary
Secondary
Osteonecrosis Other Serious Female 7/1/2008 Italy
Primary
Secondary
Osteonecrosis Other Serious 84 Male 7/10/2008 Other Health Professional Brazil
Primary
Secondary
Tooth Extraction Other Serious 61 8/15/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Weight Decreased Other Serious 53 Female 8/25/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 64 Female 8/25/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Weight Decreased Other Serious 63 Female 8/25/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 62 Female 8/25/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Toothache Other Serious 59 Female 8/25/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Pain Other Serious 43 Female 8/25/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 55 Female 8/25/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 63 Male 8/25/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Weight Decreased Other Serious 64 Female 8/25/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Osteonecrosis Other Serious Female 11/20/2008 United States
Primary
Secondary
Spinal Cord Compression Other Serious 12/31/2008 United Kingdom
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 72 Female 1/19/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vitamin D Deficiency Required Intervention 82 Female 1/20/2009 Other Health Professional United Kingdom
Primary
Secondary
Tooth Extraction Other Serious 61 1/28/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Vomiting 4/17/2008 77 Male 119 lb 1/28/2009 Physician Japan
Primary
Concomitant
Tooth Extraction Other Serious 63 Female 2/14/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 70 Female 2/14/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 71 Female 2/14/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 5/1/2008 Female 2/26/2009 Physician Germany
Primary
Concomitant
Interacting
Tibia Fracture Other Serious 8/1/2003 62 Male 3/18/2009 Physician Australia
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 77 Male 4/6/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Bearing Difficulty Other Serious 1/1/1986 Male 4/8/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 6/1/2007 70 Female 4/8/2009 Other Health Professional United States
Primary
Secondary
Osteonecrosis Other Serious 72 Male 4/23/2009 Other Health Professional Italy
Primary
Secondary
Sinus Perforation Other Serious 49 Female 4/28/2009 Other Health Professional Italy
Primary
Secondary
Osteonecrosis Other Serious 70 Female 5/4/2009 Other Health Professional Italy
Primary
Secondary
Tooth Extraction Other Serious 56 Female 5/5/2009 Other Health Professional Italy
Primary
Secondary
Tooth Infection Other Serious 66 Female 5/5/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 72 Male 5/5/2009 Other Health Professional Israel
Primary
Secondary
Scar Other Serious Female 4/15/2009 Consumer United States
Primary
Secondary
Scar Other Serious Female 4/15/2009 Consumer United States
Primary
Secondary
Pain Other Serious Male 4/15/2009 Consumer United States
Primary
Secondary
Tooth Extraction Other Serious 79 Male 154 lb 5/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tooth Extraction Hospitalization 64 Female 5/22/2009 Other Health Professional Hungary
Primary
Secondary
Surgery Other Serious 78 Female 6/5/2009 Other Health Professional United States
Primary
Secondary
Tooth Extraction Other Serious 48 Male 6/5/2009 Other Health Professional United States
Primary
Secondary
Osteonecrosis Other Serious 6/5/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 81 Female 7/22/2009 Physician Japan
Primary
Secondary
Concomitant
Surgery Other Serious 7/23/2009 Other Health Professional Greece
Primary
Secondary
Surgery Other Serious 7/23/2009 Other Health Professional Greece
Primary
Secondary
Surgery Other Serious 7/23/2009 Other Health Professional Greece
Primary
Secondary
Surgery Other Serious 7/23/2009 Other Health Professional Greece
Primary
Secondary
Osteonecrosis Other Serious 7/28/2009 Other Health Professional Greece
Primary
Secondary
Osteonecrosis Other Serious 8/3/2009 Other Health Professional Greece
Primary
Secondary
Osteonecrosis Other Serious 8/3/2009 Other Health Professional Greece
Primary
Secondary
Osteonecrosis Other Serious 8/3/2009 Other Health Professional Greece
Primary
Secondary
Osteonecrosis Other Serious 8/3/2009 Other Health Professional Greece
Primary
Secondary
Osteonecrosis Other Serious 8/3/2009 Other Health Professional Greece
Primary
Secondary
Surgery Other Serious 8/3/2009 Other Health Professional Greece
Primary
Secondary
Osteonecrosis Other Serious 8/3/2009 Other Health Professional Greece
Primary
Secondary
Osteonecrosis Other Serious 8/3/2009 Other Health Professional Greece
Primary
Secondary
Osteonecrosis Other Serious 8/6/2009 Other Health Professional Greece
Primary
Secondary
Osteonecrosis Other Serious 8/6/2009 Other Health Professional Greece
Primary
Secondary
Osteonecrosis Other Serious 8/6/2009 Other Health Professional Greece
Primary
Secondary
Osteonecrosis Other Serious 8/6/2009 Other Health Professional Greece
Primary
Secondary
Osteonecrosis Other Serious 8/6/2009 Other Health Professional Greece
Primary
Secondary
Osteonecrosis Other Serious 8/6/2009 Other Health Professional Greece
Primary
Secondary
Vomiting Other Serious 71 Male 8/7/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 8/11/2009 Other Health Professional Greece
Primary
Secondary
Osteonecrosis Other Serious 81 Female 8/12/2009 Physician Japan
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 8/13/2009 Other Health Professional Greece
Primary
Secondary
Osteonecrosis Other Serious 8/17/2009 Other Health Professional Greece
Primary
Secondary
Osteonecrosis Other Serious 8/18/2009 Other Health Professional Greece
Primary
Secondary
Osteonecrosis Other Serious 8/18/2009 Other Health Professional Greece
Primary
Secondary
Osteonecrosis Other Serious 8/18/2009 Other Health Professional Greece
Primary
Secondary
Osteonecrosis Other Serious 8/19/2009 Other Health Professional Greece
Primary
Secondary
Osteonecrosis Other Serious 8/19/2009 Other Health Professional Greece
Primary
Secondary
Toothache Other Serious 56 Female 8/25/2009 Canada
Primary
Secondary
Concomitant
Toothache Other Serious 12/1/1994 67 Female 8/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Toothache Other Serious 6/1/2005 45 Male 8/28/2009 Other Health Professional France
Primary
Secondary
Tooth Extraction Other Serious 72 Female 9/2/2009 Other Health Professional Greece
Primary
Secondary
Osteonecrosis Other Serious 43 Female 9/2/2009 Other Health Professional France
Primary
Secondary
Osteonecrosis Other Serious 67 Male 9/2/2009 Other Health Professional France
Primary
Secondary
Osteonecrosis Other Serious 59 Female 9/2/2009 Other Health Professional France
Primary
Secondary

Drug Data