Mitoxantrone



Indications and Reactions:

Role Indications Reactions
Primary
Lymphoma 19.8%
Acute Myeloid Leukaemia 17.7%
Multiple Sclerosis 13.4%
Relapsing-remitting Multiple Sclerosis 6.7%
Acute Promyelocytic Leukaemia 6.4%
Secondary Progressive Multiple Sclerosis 5.9%
Non-hodgkin's Lymphoma 4.6%
Breast Cancer Metastatic 4.1%
Prostate Cancer 4.1%
Follicle Centre Lymphoma, Follicular Grade I, Ii, Iii Stage Iv 3.1%
B-cell Lymphoma 2.8%
Acute Lymphocytic Leukaemia 2.3%
Neuromyelitis Optica 1.5%
Myelodysplastic Syndrome 1.3%
Prostate Cancer Metastatic 1.3%
Breast Cancer 1.0%
Neoplasm 1.0%
Product Used For Unknown Indication 1.0%
T-cell Prolymphocytic Leukaemia 1.0%
Chronic Lymphocytic Leukaemia 0.8%
Acute Promyelocytic Leukaemia 22.7%
Acute Myeloid Leukaemia 13.6%
Neutropenia 11.8%
Thrombocytopenia 7.3%
Pancytopenia 5.5%
Pyrexia 4.5%
Acute Febrile Neutrophilic Dermatosis 3.6%
Myelodysplastic Syndrome 3.6%
Pneumonia 2.7%
Progressive Multifocal Leukoencephalopathy 2.7%
Pulmonary Alveolar Haemorrhage 2.7%
Sepsis 2.7%
Vomiting 2.7%
White Blood Cell Count Decreased 2.7%
Acute Leukaemia 1.8%
Acute Myelomonocytic Leukaemia 1.8%
Febrile Neutropenia 1.8%
Multi-organ Failure 1.8%
Nausea 1.8%
Neutropenic Sepsis 1.8%
Secondary
Acute Myeloid Leukaemia 20.4%
B-cell Lymphoma 11.2%
Chronic Lymphocytic Leukaemia 9.5%
Product Used For Unknown Indication 8.6%
Non-hodgkin's Lymphoma 7.9%
Drug Use For Unknown Indication 5.5%
Acute Promyelocytic Leukaemia 5.4%
Diffuse Large B-cell Lymphoma 5.2%
Acute Lymphocytic Leukaemia 5.1%
Prostate Cancer Metastatic 2.9%
Prophylaxis 2.8%
Lymphoma 2.7%
Prostate Cancer 2.2%
T-cell Prolymphocytic Leukaemia 2.1%
Acute Monocytic Leukaemia 2.0%
Breast Cancer 2.0%
Mantle Cell Lymphoma 1.7%
Acute Myeloid Leukaemia Recurrent 1.0%
Infection Prophylaxis 0.9%
Leukaemia 0.9%
Myelodysplastic Syndrome 11.5%
Febrile Neutropenia 8.6%
Thrombocytopenia 8.4%
Bacterial Sepsis 7.4%
Acute Myeloid Leukaemia 6.6%
White Blood Cell Count Decreased 6.4%
Cardiac Failure 5.7%
Sepsis 5.7%
Pneumonia 5.4%
Vomiting 5.4%
Neutropenia 4.7%
Off Label Use 3.9%
Progressive Multifocal Leukoencephalopathy 3.2%
Lung Neoplasm Malignant 2.9%
Hepatitis B 2.7%
Septic Shock 2.7%
Death 2.2%
Non-small Cell Lung Cancer 2.2%
Pancytopenia 2.2%
Pleural Effusion 2.2%
Concomitant
Acute Myeloid Leukaemia 16.9%
Product Used For Unknown Indication 11.1%
B-cell Lymphoma 8.9%
Drug Use For Unknown Indication 8.5%
Chemotherapy 7.1%
Non-hodgkin's Lymphoma 6.8%
Metastases To Bone 4.9%
Multiple Sclerosis 4.4%
Acute Lymphocytic Leukaemia 4.0%
Diffuse Large B-cell Lymphoma 3.9%
Prophylaxis 3.3%
Chronic Lymphocytic Leukaemia 3.2%
Prostate Cancer 2.8%
Acute Promyelocytic Leukaemia 2.4%
Breast Cancer 2.4%
Stem Cell Transplant 2.2%
Prostate Cancer Metastatic 2.0%
Breast Cancer Metastatic 1.9%
Prophylaxis Against Graft Versus Host Disease 1.7%
Acute Lymphocytic Leukaemia Recurrent 1.6%
Weight Decreased 10.2%
White Blood Cell Count Decreased 9.0%
Pneumonitis 6.6%
Wheezing 6.6%
Drug Ineffective 5.4%
Oedema Peripheral 5.4%
Progressive Multifocal Leukoencephalopathy 5.4%
Pyrexia 5.4%
Vomiting 5.4%
Myelodysplastic Syndrome 4.2%
Nausea 4.2%
Oesophagitis 4.2%
Sepsis 4.2%
Tooth Extraction 4.2%
Rash 3.6%
Urinary Incontinence 3.6%
Febrile Neutropenia 3.0%
Palmar-plantar Erythrodysaesthesia Syndrome 3.0%
Red Blood Cell Count Decreased 3.0%
Septic Shock 3.0%