Cytarabine combined with Mitoxantrone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Decreased Hospitalization 11/9/2005 64 Male 171 lb 1/5/2006 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/20/2005 71 Female 108 lb 1/5/2006 United States
Primary
Secondary
Vomiting Hospitalization 7/25/2004 56 Female 106 lb 1/18/2006 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/20/2005 71 Female 108 lb 2/2/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Life Threatening 1/17/2005 Male 207 lb 2/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Herpes Simplex Other Serious 6/10/2005 26 Female 182 lb 2/14/2006 United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 1/25/2006 81 Male 160 lb 3/4/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 1/25/2006 81 Male 160 lb 3/23/2006 Physician United States
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 2/23/2006 53 Female 131 lb 3/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 1/25/2006 81 Male 160 lb 4/1/2006 United States
Primary
Secondary
Concomitant
Skin Exfoliation Hospitalization 2/21/2006 Female 4/13/2006 Pharmacist United States
Primary
Secondary
Concomitant
Monoplegia Other Serious 11/28/2005 58 Male 4/10/2006 France
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 5/27/2005 48 Female 152 lb 4/12/2006 United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/17/2006 55 Male 4/20/2006 United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 1/25/2006 81 Male 160 lb 4/20/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 2/23/2006 53 Female 131 lb 4/20/2006 United States
Primary
Secondary
Concomitant
Herpes Simplex Other Serious 6/10/2005 26 Female 182 lb 4/19/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 5/27/2005 48 Female 152 lb 4/21/2006 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2005 57 Female 108 lb 5/5/2006 Physician Japan
Primary
Secondary
Concomitant
Ejection Fraction Decreased Hospitalization 4/28/2006 53 Female 185 lb 6/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Hypokinesia Hospitalization 4/28/2006 53 Female 185 lb 5/27/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2005 57 Female 108 lb 6/1/2006 Physician Japan
Primary
Secondary
Concomitant
Rash Hospitalization 6/20/2006 65 Female 245 lb 6/20/2006 Pharmacist United States
Primary
Concomitant
Neutropenic Infection Hospitalization 5/15/2006 68 Male 148 lb 6/24/2006 Physician United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 7/9/2005 53 Female 201 lb 6/30/2006 United States
Primary
Concomitant
Stenotrophomonas Infection Other Serious 9/1/2002 59 Male 7/7/2006 France
Primary
Secondary
Transaminases Increased Other Serious 5/27/2005 48 Female 152 lb 7/11/2006 United States
Primary
Concomitant
Stomatitis Hospitalization 1/25/2006 81 Male 160 lb 7/15/2006 United States
Primary
Secondary
Concomitant
Hypotension Life Threatening 1/10/2006 53 Female 152 lb 7/14/2006 Other Health Professional United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 7/27/2005 57 Female 108 lb 7/14/2006 Physician Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 6/21/2006 62 Male 214 lb 7/19/2006 Physician United States
Primary
Secondary
Febrile Neutropenia Hospitalization 6/21/2006 62 Male 214 lb 7/29/2006 Physician United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 6/27/2004 56 Female 6/14/2006 United States
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 2/25/2006 59 Male 160 lb 8/12/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/15/2006 68 Male 148 lb 8/12/2006 Physician United States
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 7/9/2005 53 Female 201 lb 9/1/2006 United States
Primary
Concomitant
Therapy Non-responder Hospitalization 1/1/2006 Female 108 lb 9/7/2006 Physician Portugal
Primary
Concomitant
Transplant Failure Death 48 Male 9/1/2006 Germany
Primary
Secondary
Concomitant
Lacunar Infarction Hospitalization 8/8/2006 70 Female 164 lb 9/9/2006 Physician United States
Primary
Secondary
Viral Infection Other Serious 45 Female 9/20/2006 Physician Germany
Primary
Secondary
Concomitant
Ejection Fraction Decreased Hospitalization 4/28/2006 53 Female 185 lb 9/29/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 5/15/2006 68 Male 148 lb 9/27/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 4/28/2006 53 Female 185 lb 9/29/2006 Physician United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 11/1/2005 67 Male 10/9/2006 Physician Japan
Primary
Secondary
Therapy Non-responder Hospitalization 1/1/2006 Female 108 lb 10/12/2006 Physician Portugal
Primary
Concomitant
Oedema Peripheral Other Serious 7/27/2005 57 Female 108 lb 10/12/2006 Physician Japan
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 11/1/2005 67 Male 10/25/2006 Physician Japan
Primary
Secondary
Splenomegaly Hospitalization 1/1/2006 Female 108 lb 12/8/2006 Physician Portugal
Primary
Concomitant
Thrombocytopenia Death 5/4/2005 69 Female 12/4/2006 Netherlands
Primary
Concomitant
Thrombocytopenia Hospitalization 8/16/2006 35 Female 187 lb 12/7/2006 Other Health Professional France
Primary
Secondary
White Blood Cell Count Increased Other Serious 3/14/2006 53 Male 215 lb 12/12/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 11/7/2006 77 Male 155 lb 12/12/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Death 6/26/2005 Male 166 lb 2/2/2007 Physician Germany
Primary
Secondary
White Blood Cell Count Decreased Other Serious 1/6/2007 67 Male 1/30/2007 Other Health Professional United States
Primary
Secondary
Ventricular Failure Hospitalization 4/28/2006 53 Female 185 lb 2/2/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Hospitalization 2/18/2006 55 Male 2/9/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 11/20/2005 71 Female 108 lb 2/10/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 8/16/2006 35 Female 187 lb 2/22/2007 Other Health Professional France
Primary
Secondary
Subdural Haematoma Other Serious 1/1/1994 52 Female 3/1/2007
Primary
Secondary
Lacunar Infarction Hospitalization 8/8/2006 70 Female 164 lb 2/22/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Tracheobronchitis Hospitalization 8/1/2003 Female 139 lb 3/14/2007 Physician Portugal
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 2/1/2005 Female 154 lb 3/26/2007 Physician Italy
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 2/6/2007 5 Female 3/22/2007 United States
Primary
Concomitant
Pancytopenia Other Serious 4/2/2007 Other Health Professional Italy
Primary
Secondary
White Blood Cell Count Decreased Other Serious 1/6/2007 67 Male 3/27/2007 United States
Primary
Secondary
Inappropriate Antidiuretic Hormone Secretion Hospitalization 66 Female 4/3/2007
Primary
Secondary
White Blood Cell Count Decreased Other Serious 1/6/2007 67 Male 207 lb 3/28/2007 Other Health Professional United States
Primary
Secondary
Liver Disorder Death 61 Male 4/5/2007 Japan
Primary
Secondary
Pulmonary Alveolar Haemorrhage Life Threatening 1/10/2007 Male 165 lb 4/10/2007 Physician Italy
Primary
Secondary
Myocardial Infarction Death 6/26/2005 Male 166 lb 4/24/2007 Physician Germany
Primary
Secondary
Sepsis Life Threatening 3/2/2007 67 Male 5/1/2007 Other Health Professional United States
Primary
Secondary
Superior Sagittal Sinus Thrombosis Other Serious 25 Male 151 lb 5/9/2007 Japan
Primary
Secondary
Concomitant
Tracheobronchitis Other Serious 8/1/2003 Female 139 lb 5/25/2007 Physician Portugal
Primary
Secondary
Concomitant
Immunosuppression Hospitalization 4/22/2007 55 Female 185 lb 5/23/2007 Other Health Professional United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 4/9/2007 42 Male 140 lb 5/26/2007 Consumer United States
Primary
Secondary
Superior Sagittal Sinus Thrombosis Life Threatening 25 Male 151 lb 6/19/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Pneumonia Life Threatening 5/21/2007 22 Male 6/21/2007 Other Health Professional United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 5/22/2007 64 Male 187 lb 6/23/2007 Other Health Professional United States
Primary
Secondary
Supraventricular Tachycardia Life Threatening 3/2/2007 67 Male 7/12/2007 Other Health Professional United States
Primary
Secondary
Febrile Neutropenia Hospitalization 6/1/2007 64 Male 182 lb 7/14/2007 United States
Primary
Secondary
Cerebellar Syndrome Hospitalization 5/21/2007 Male 8/1/2007 Other Health Professional France
Primary
Secondary
Concomitant
Supraventricular Tachycardia Life Threatening 3/2/2007 67 Male 8/1/2007 Other Health Professional United States
Primary
Secondary
Ureteric Obstruction Hospitalization 6/5/2007 Female 53 lb 7/27/2007 United States
Primary
Secondary
Septic Shock Death 6/30/2007 Male 150 lb 8/9/2007 Physician Italy
Primary
Secondary
Concomitant
Renal Failure Other Serious 7/13/2007 53 Male 8/21/2007 Other Health Professional United States
Primary
Secondary
Respiratory Arrest Other Serious 7/13/2007 53 Male 8/24/2007 Other Health Professional United States
Primary
Secondary
Febrile Neutropenia Hospitalization 4/22/2007 55 Female 185 lb 9/15/2007 United States
Primary
Secondary
Thrombocytopenia Other Serious 85 Male 9/17/2007 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 72 Female 9/17/2007 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 78 Male 9/17/2007 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 72 Male 9/17/2007 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 66 Male 9/17/2007 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Death 75 Male 9/17/2007 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 78 Male 9/17/2007 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 70 Female 9/17/2007 Japan
Primary
Secondary
Concomitant
Sepsis Death 10/25/2007 Physician Italy
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 7/1/2003 Female 128 lb 10/26/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 70 Female 11/13/2007 Consumer United States
Primary
Secondary
Concomitant
Sepsis Other Serious 70 Female 11/26/2007 Consumer Japan
Primary
Secondary
Concomitant
Shock Other Serious 58 Male 11/27/2007 Other Health Professional Poland
Primary
Secondary
Malignant Neoplasm Progression Other Serious 67 Male 11/27/2007 Other Health Professional Poland
Primary
Secondary
Thrombocytopenia Other Serious 67 Male 11/29/2007 Other Health Professional Poland
Primary
Secondary
Thrombocytopenia Other Serious 58 Male 11/29/2007 Other Health Professional Poland
Primary
Secondary
Myelodysplastic Syndrome Death 56 Male 2/25/2008 Physician United States
Primary
Secondary
Myelodysplastic Syndrome Other Serious 45 Female 2/25/2008 Physician United States
Primary
Secondary
Myelodysplastic Syndrome Other Serious 45 Female 2/27/2008 Physician United States
Primary
Secondary
Myelodysplastic Syndrome Death 56 Male 2/27/2008 Consumer United Kingdom
Primary
Secondary
Myelodysplastic Syndrome Death 56 Male 3/5/2008 Consumer United Kingdom
Primary
Secondary
Myelodysplastic Syndrome Death 45 Female 3/5/2008 Physician United States
Primary
Secondary
Myelodysplastic Syndrome Death 45 Female 3/5/2008 Physician United States
Primary
Secondary
Vith Nerve Paralysis Other Serious 52 Female 3/12/2008 Other Health Professional United Kingdom
Primary
Secondary
Pulmonary Oedema Other Serious 2 Female 3/15/2008 Physician United States
Primary
Secondary
Pulmonary Oedema Other Serious 2 Male 3/15/2008 Physician United States
Primary
Secondary
Viral Upper Respiratory Tract Infection Other Serious 1 Male 3/15/2008 Physician United States
Primary
Secondary
Concomitant
Venous Thrombosis Other Serious 1 Female 3/15/2008 Physician United States
Primary
Secondary
Gene Mutation Other Serious 9 Male 3/24/2008 France
Primary
Concomitant
Pregnancy Other Serious 36 Female 3/25/2008 Brazil
Primary
Secondary
Vith Nerve Paralysis Other Serious 52 Female 3/26/2008 Other Health Professional United Kingdom
Primary
Secondary
Hodgkin's Disease Recurrent Other Serious 36 Female 4/2/2008 Brazil
Primary
Secondary
Cytogenetic Abnormality Other Serious 9 Male 3/30/2008 France
Primary
Secondary
Vth Nerve Injury Other Serious 52 Female 4/4/2008 Other Health Professional United Kingdom
Primary
Secondary
Febrile Neutropenia Other Serious 6/8/2007 31 Male 4/11/2008 Physician Turkey
Primary
Secondary
Pyrexia Other Serious 58 Male 4/16/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Cardiomyopathy Death Female 4/17/2008 United States
Primary
Secondary
Cardio-respiratory Arrest Death 4/17/2008 United States
Primary
Secondary
Respiratory Disorder Death 4/17/2008 United States
Primary
Secondary
Viral Upper Respiratory Tract Infection Death Female 4/17/2008 United States
Primary
Secondary
Pulmonary Oedema Death Female 4/17/2008 United States
Primary
Secondary
Sinusitis Fungal Hospitalization 52 Female 4/23/2008 United Kingdom
Primary
Secondary
Concomitant
Pneumonia Respiratory Syncytial Viral Other Serious Unknown 4/28/2008 United States
Primary
Secondary
Viral Upper Respiratory Tract Infection Other Serious Female 4/28/2008 United States
Primary
Secondary
Vena Cava Thrombosis Other Serious Female 4/28/2008 United States
Primary
Secondary
Cardio-respiratory Arrest Other Serious Unknown 4/28/2008 United States
Primary
Secondary
Respiratory Disorder Other Serious Unknown 4/28/2008 United States
Primary
Secondary
Sepsis Other Serious 8/12/2007 Male 119 lb 5/6/2008 Physician Japan
Primary
Secondary
Stomatitis Life Threatening 6/12/2007 52 Female 4/30/2008 Japan
Primary
Concomitant
Petit Mal Epilepsy Disability 2/3/2008 22 Female 99 lb 5/12/2008 Physician Poland
Primary
Concomitant
Skin Exfoliation Other Serious 17 Female 5/29/2008 Physician Turkey
Primary
Secondary
Palmar Erythema Other Serious 17 Female 6/11/2008 Turkey
Primary
Secondary
Stem Cell Transplant Other Serious Female 6/14/2008 Consumer United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious Male 6/14/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious Female 6/14/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious Male 6/14/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 68 Female 6/19/2008 United States
Primary
Secondary
Myelodysplastic Syndrome Other Serious 42 Male 6/23/2008 Other Health Professional United States
Primary
Secondary
Myelodysplastic Syndrome Other Serious 68 Female 6/23/2008 Other Health Professional United States
Primary
Secondary
Myelodysplastic Syndrome Death 68 Female 6/24/2008 United States
Primary
Secondary
Myelodysplastic Syndrome Other Serious 68 Female 6/25/2008 Other Health Professional United States
Primary
Secondary
Sepsis Other Serious 8/12/2007 Male 119 lb 7/2/2008 Physician Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 7/7/2008 Japan
Primary
Secondary

Drug Data