Cyclophosphamide combined with Mitoxantrone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Paralysis Other Serious 10/1/2005 66 Male 168 lb 1/13/2006 Physician Germany
Primary
Concomitant
White Blood Cell Count Increased Other Serious 38 Female 1/23/2006 Physician France
Primary
Secondary
Concomitant
Transplant Life Threatening 7/2/2005 59 Male 139 lb 2/22/2006 Physician France
Primary
Secondary
Concomitant
Peritoneal Carcinoma Life Threatening 7/2/2005 59 Male 139 lb 3/6/2006 Physician France
Primary
Secondary
Concomitant
Sputum Culture Positive Hospitalization 1/25/2006 73 Male 130 lb 3/17/2006 Other Health Professional Thailand
Primary
Secondary
Metastases To Peritoneum Life Threatening 7/2/2005 59 Male 139 lb 3/16/2006 Physician France
Primary
Secondary
Concomitant
Ventricular Arrhythmia Hospitalization 10/8/2003 76 Male 225 lb 4/17/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Hospitalization 3/23/2006 Male 5/15/2006 Physician Hungary
Primary
Concomitant
West Nile Viral Infection Other Serious 57 Male 5/12/2006 United States
Primary
Secondary
Aplasia Pure Red Cell Hospitalization 3/23/2006 Male 6/7/2006 Physician Hungary
Primary
Concomitant
Pneumonia Death 6/15/2006 Austria
Primary
Secondary
Nonspecific Reaction Hospitalization 6/17/2006 56 Male 187 lb 7/18/2006 Physician Spain
Primary
Secondary
Septic Shock Death 7/24/2006 58 Male 126 lb 8/18/2006 Other Health Professional Spain
Primary
Concomitant
Febrile Neutropenia Hospitalization 8/1/2006 56 Male 173 lb 8/22/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Therapy Non-responder Hospitalization 1/1/2006 Female 108 lb 9/7/2006 Physician Portugal
Primary
Concomitant
Pneumonitis Other Serious 53 Male 6/6/2006 Pharmacist United States
Primary
Concomitant
Viral Infection Other Serious 45 Female 9/20/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Viral Infection Other Serious 45 Female 9/20/2006 Physician Germany
Primary
Secondary
Concomitant
Therapy Non-responder Hospitalization 1/1/2006 Female 108 lb 10/12/2006 Physician Portugal
Primary
Concomitant
Pancytopenia Other Serious 66 Female 11/22/2006 Physician Australia
Primary
Secondary
Malignant Neoplasm Progression Other Serious 53 Male 11/22/2006 Physician Australia
Primary
Secondary
Splenomegaly Hospitalization 1/1/2006 Female 108 lb 12/8/2006 Physician Portugal
Primary
Concomitant
Weight Decreased Other Serious 12/1/2004 49 Male 2/10/2007 Japan
Primary
Concomitant
Pulmonary Fibrosis Other Serious 6/1/2006 77 Male 181 lb 2/22/2007 Physician Germany
Primary
Concomitant
Pulmonary Fibrosis Other Serious 6/1/2006 77 Male 181 lb 3/22/2007 Physician Germany
Primary
Secondary
Concomitant
Pancytopenia Other Serious 4/2/2007 Other Health Professional Italy
Primary
Secondary
Neutropenic Sepsis Death 66 Female 4/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Chronic Myelomonocytic Leukaemia Death 53 Male 4/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Myelodysplastic Syndrome Life Threatening 2/21/2007 65 Female 4/11/2007 Other Health Professional United States
Primary
Concomitant
Myelodysplastic Syndrome Death 52 Female 4/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Diplopia Hospitalization 5/15/2006 Male 4/26/2007 Consumer United Kingdom
Primary
Secondary
Diplopia Hospitalization 5/15/2006 73 Male 5/17/2007 Consumer United States
Primary
Secondary
Superior Sagittal Sinus Thrombosis Other Serious 25 Male 151 lb 5/9/2007 Japan
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Hospitalization 8/14/2006 Female 185 lb 6/21/2007 Physician France
Primary
Secondary
Pulmonary Tuberculosis Hospitalization 8/14/2006 Female 185 lb 6/22/2007 Physician France
Primary
Secondary
Superior Sagittal Sinus Thrombosis Life Threatening 25 Male 151 lb 6/19/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Post Procedural Complication Death 8/8/2005 67 Male 7/16/2007 Other Health Professional Poland
Primary
Concomitant
Diplopia Hospitalization 5/15/2006 73 Male 8/1/2007 United Kingdom
Primary
Secondary
Pulmonary Fibrosis Other Serious 6/1/2006 Male 181 lb 8/24/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/25/2006 Male 130 lb 10/17/2007 Consumer France
Primary
Secondary
Sepsis Death 10/25/2007 Physician Italy
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 7/1/2003 Female 128 lb 10/26/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Shock Death 8/8/2005 67 Male 10/30/2007 Other Health Professional Poland
Primary
Concomitant
Pneumonia Bacterial Death 6/20/2007 Male 11/10/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 1/2/2006 Male 194 lb 11/12/2007 Consumer France
Primary
Secondary
Shock Other Serious 58 Male 11/27/2007 Other Health Professional Poland
Primary
Secondary
Malignant Neoplasm Progression Other Serious 67 Male 11/27/2007 Other Health Professional Poland
Primary
Secondary
Febrile Neutropenia Hospitalization 8/2/2007 Female 123 lb 11/28/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 67 Male 11/29/2007 Other Health Professional Poland
Primary
Secondary
Thrombocytopenia Other Serious 58 Male 11/29/2007 Other Health Professional Poland
Primary
Secondary
Red Blood Cell Count Decreased Hospitalization 8/1/2007 53 Female 11/27/2007 Germany
Primary
Concomitant
Pneumonia Bacterial Death 6/20/2007 Male 12/7/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Death 8/8/2005 67 Male 12/7/2007 Other Health Professional Poland
Primary
Concomitant
Febrile Neutropenia Hospitalization 5/25/2007 Male 141 lb 12/13/2007 Consumer United Kingdom
Primary
Secondary
Acute Respiratory Failure Hospitalization 12/5/2007 Male 12/22/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Acute Respiratory Failure Hospitalization 12/5/2007 Male 1/2/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Neurological Symptom Life Threatening 12/24/2007 Male 154 lb 1/22/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Acute Myelomonocytic Leukaemia Death 68 Male 2/23/2008 Consumer United Kingdom
Primary
Secondary
Acute Myeloid Leukaemia Death 75 Female 2/23/2008 Consumer United Kingdom
Primary
Secondary
Myelodysplastic Syndrome Death 56 Male 2/25/2008 Physician United States
Primary
Secondary
Myelodysplastic Syndrome Other Serious 45 Female 2/25/2008 Physician United States
Primary
Secondary
Myelodysplastic Syndrome Death 58 2/26/2008 Consumer United Kingdom
Primary
Secondary
Myelodysplastic Syndrome Other Serious 45 Female 2/27/2008 Physician United States
Primary
Secondary
Myelodysplastic Syndrome Death 56 Male 2/27/2008 Consumer United Kingdom
Primary
Secondary
Therapeutic Response Decreased Death 68 Male 3/5/2008 Consumer United Kingdom
Primary
Secondary
Myelodysplastic Syndrome Death 56 Male 3/5/2008 Consumer United Kingdom
Primary
Secondary
Myelodysplastic Syndrome Death 45 Female 3/5/2008 Physician United States
Primary
Secondary
Acute Myeloid Leukaemia Death 75 Female 3/5/2008 Consumer United Kingdom
Primary
Secondary
Myelodysplastic Syndrome Death 58 3/5/2008 Consumer United Kingdom
Primary
Secondary
Myelodysplastic Syndrome Death 45 Female 3/5/2008 Physician United States
Primary
Secondary
Thrombocytopenia Other Serious 8/27/2003 44 Female 134 lb 3/6/2008 Physician Spain
Primary
Secondary
Concomitant
Aspiration Bronchial Other Serious 3/10/2008 Spain
Primary
Secondary
Concomitant
Aspiration Bronchial Other Serious 3/12/2008 Spain
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious Female 3/19/2008 Physician United Kingdom
Primary
Concomitant
Trichosporon Infection Death 9/13/2006 77 Male 3/19/2008 Physician Japan
Primary
Secondary
Neutropenic Sepsis Hospitalization 2/20/2008 Female 4/1/2008 Physician United Kingdom
Primary
Concomitant
Non-hodgkin's Lymphoma Other Serious 71 Female 4/8/2008 Other Health Professional Italy
Primary
Secondary
Non-hodgkin's Lymphoma Other Serious 71 Female 4/11/2008 Other Health Professional Italy
Primary
Secondary
Chronic Myeloid Leukaemia Other Serious 71 Female 4/14/2008 Italy
Primary
Secondary
Platelet Count Decreased Other Serious 3/10/2008 71 Male 163 lb 4/14/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Death 55 Male 4/16/2008 Consumer Japan
Primary
Concomitant
Non-hodgkin's Lymphoma Recurrent Other Serious 71 Female 4/16/2008 Italy
Primary
Secondary
Platelet Count Decreased Other Serious 3/10/2008 71 Male 163 lb 4/18/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tremor Other Serious 3/10/2008 71 Male 165 lb 4/18/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 12/13/2007 Female 143 lb 4/19/2008 Consumer United Kingdom
Primary
Secondary
Non-hodgkin's Lymphoma Other Serious 71 Female 4/29/2008 Consumer Japan
Primary
Secondary
Non-hodgkin's Lymphoma Other Serious 1/1/2005 71 Female 4/24/2008 Italy
Primary
Secondary
Concomitant
Non-hodgkin's Lymphoma Other Serious 12/1/1995 52 Female 5/5/2008 Consumer Japan
Primary
Secondary
Transplant Rejection Death 6/3/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Bacterial Sepsis Death 6/3/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Gastric Cancer Death 6/3/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Colon Cancer Other Serious 2/12/2008 66 Male 6/9/2008 Consumer United Kingdom
Primary
Secondary
Febrile Neutropenia Hospitalization 7/23/2007 Male 172 lb 6/26/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 5/7/2006 Female 132 lb 7/2/2008 Physician France
Primary
Secondary
Hepatitis C Virus Test Other Serious 11/1/2005 68 Male 6/27/2008 Taiwan, Province Of China
Primary
Secondary
Concomitant
Colon Cancer Other Serious 2/12/2008 7/10/2008 Consumer United Kingdom
Primary
Secondary
Pneumonia Hospitalization 1/2/2006 Male 130 lb 7/22/2008 Consumer France
Primary
Secondary
Respiratory Failure Other Serious 8/1/2003 76 Female 8/5/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Guillain-barre Syndrome Other Serious 42 Male 8/5/2008 Other Health Professional United States
Primary
Secondary
Leukaemia Other Serious 39 Female 8/5/2008 United States
Primary
Secondary
Guillain-barre Syndrome Other Serious 39 Female 8/5/2008 Other Health Professional United States
Primary
Secondary
Stem Cell Transplant Death 39 Female 8/9/2008 United States
Primary
Secondary
Stem Cell Transplant Disability 39 Female 8/20/2008 Physician United States
Primary
Secondary
Psychotic Disorder Other Serious 44 Male 8/21/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Pneumonia Fungal Death 76 Female 8/26/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pneumonia Other Serious Female 9/11/2008 Physician Hungary
Primary
Secondary
Pneumonia Other Serious Female 9/11/2008 Physician Hungary
Primary
Secondary
Pneumonia Death 49 Male 9/18/2008 Physician Hungary
Primary
Secondary
Pneumonia Death 66 Female 9/19/2008 Physician Hungary
Primary
Secondary
Thrombotic Microangiopathy Other Serious 44 Female 9/29/2008 Japan
Primary
Secondary
Thrombotic Microangiopathy Other Serious 44 Female 10/7/2008 Japan
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Hospitalization 4/1/2000 64 Male 10/10/2008 Physician Australia
Primary
Secondary
Concomitant
Leukaemia Other Serious 5/1/2008 66 Male 10/28/2008 Physician Japan
Primary
Concomitant
Unrelated Donor Bone Marrow Transplantation Therapy Death 1/1/2007 56 Female 10/27/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Pneumonia Bacterial Hospitalization 1/2/2006 Male 130 lb 11/17/2008 Consumer France
Primary
Secondary
Leukaemia Other Serious 5/10/2008 69 Male 11/25/2008 Physician Japan
Primary
Concomitant
Non-hodgkin's Lymphoma Recurrent Other Serious 1/1/2005 71 Female 4/18/2008 Italy
Primary
Secondary
Hyperammonaemic Encephalopathy Death 69 Male 12/11/2008 Other Health Professional Australia
Primary
Secondary
Hyperammonaemic Encephalopathy Death 69 Male 12/16/2008 Other Health Professional United Kingdom
Primary
Secondary
Respiratory Alkalosis Death 69 Male 12/12/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 6/1/2008 Female 12/24/2008 Physician Germany
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 10/8/2008 Male 12/24/2008 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Death 43 Female 12/29/2008 Physician United Kingdom
Primary
Secondary
Neuromyelitis Optica Death 43 Female 12/31/2008 Physician United Kingdom
Primary
Secondary
Myelodysplastic Syndrome Other Serious 1/19/2009 United States
Primary
Secondary
Respiratory Alkalosis Death 69 Male 1/9/2009 Physician Australia
Primary
Secondary
Concomitant
Colon Cancer Other Serious 2/11/2008 1/21/2009 Consumer United Kingdom
Primary
Secondary
Stem Cell Transplant Death 50 Unknown 1/21/2009 Physician United States
Primary
Secondary
Hyperammonaemic Encephalopathy Death 1/1/2005 69 Male 1/29/2009 Other Health Professional Australia
Primary
Secondary
Colon Cancer Other Serious 2/11/2008 1/30/2009 Consumer United Kingdom
Primary
Secondary
Gastrointestinal Disorder Hospitalization 12/13/2008 Male 2/26/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 10/21/2008 Female 4/9/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Hypersensitivity Other Serious 4/10/2009 Physician United Kingdom
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Other Serious 59 Female 4/22/2009 Other Health Professional United States
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious Female 105 lb 5/15/2009 Other Health Professional United States
Primary
Concomitant
Pulmonary Fibrosis Other Serious 5/1/2009 Female 5/19/2009 Pharmacist Australia
Primary
Concomitant
No Therapeutic Response Death 16 Female 6/15/2009 Other Health Professional China
Primary
Concomitant
Thrombocytopenia Other Serious 6/16/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 6/19/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Sepsis Life Threatening 6/16/2009 81 Female 98 lb 6/23/2009 Pharmacist United States
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Death 64 Female 6/26/2009 Austria
Primary
Secondary
Staphylococcal Infection Other Serious 1/1/2008 43 Male 6/29/2009 Physician United Kingdom
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Death 8/1/2008 64 Female 7/7/2009 Consumer United Kingdom
Primary
Concomitant
Pneumonia Other Serious 30 Male 7/13/2009 Consumer Japan
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Other Serious 35 8/4/2009 United Kingdom
Primary
Secondary
Pneumonia Other Serious 8/1/1997 31 Male 8/12/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Pneumonia Other Serious 52 Male 8/13/2009 Consumer Poland
Primary
Concomitant
Thrombosis Death 7/5/2009 Female 8/17/2009 Pharmacist United Kingdom
Primary
Concomitant
Pulmonary Fibrosis Other Serious 5/1/2009 Female 8/24/2009 Pharmacist Australia
Primary
Concomitant
Acute Myeloid Leukaemia Other Serious 8/19/2009 United Kingdom
Primary
Secondary

Drug Data