Hydroxyurea



Indications and Reactions:

Role Indications Reactions
Primary
Essential Thrombocythaemia 22.2%
Polycythaemia Vera 14.1%
Chronic Myeloid Leukaemia 13.1%
Sickle Cell Anaemia 5.9%
Thrombocythaemia 4.9%
Product Used For Unknown Indication 4.2%
Platelet Count Increased 3.6%
Thalassaemia Beta 3.6%
Acute Myeloid Leukaemia 3.3%
Thrombocytosis 3.3%
Myeloproliferative Disorder 2.9%
Polycythaemia 2.9%
Glioblastoma 2.6%
Hypertension 2.6%
Depression 2.3%
Myelofibrosis 2.3%
Multiple Myeloma 2.0%
Skin Ulcer 1.6%
Breast Cancer 1.3%
Leukaemia 1.3%
Skin Ulcer 12.3%
Death 11.4%
Respiratory Failure 7.0%
Acute Myeloid Leukaemia 6.1%
Thrombocytopenia 6.1%
White Blood Cell Count Abnormal 5.3%
Azoospermia 4.4%
Pregnancy 4.4%
Serum Ferritin Increased 4.4%
Thrombosis 4.4%
Tumour Lysis Syndrome 4.4%
Haemorrhage 3.5%
Platelet Count Increased 3.5%
Pyrexia 3.5%
Rash 3.5%
Transient Ischaemic Attack 3.5%
Vomiting 3.5%
White Blood Cell Count Decreased 3.5%
Adverse Drug Reaction 2.6%
Cytogenetic Analysis Abnormal 2.6%
Secondary
Essential Thrombocythaemia 32.6%
Chronic Myeloid Leukaemia 12.2%
Hiv Infection 11.9%
Glioblastoma Multiforme 6.3%
Squamous Cell Carcinoma 5.2%
Hypertension 4.6%
Acute Myeloid Leukaemia 4.2%
Drug Use For Unknown Indication 3.6%
Depression 2.3%
Neoplasm Malignant 2.3%
Head And Neck Cancer 2.3%
Acquired Immunodeficiency Syndrome 1.9%
Product Used For Unknown Indication 1.7%
Hyperuricaemia 1.6%
Migraine 1.5%
Antiretroviral Therapy 1.4%
Pain 1.2%
Sickle Cell Anaemia 1.2%
Premedication 1.1%
Astrocytoma 1.0%
White Blood Cell Count Decreased 12.8%
Neoplasm Malignant 9.7%
Thrombocytopenia 9.7%
Pneumonia 9.2%
Sepsis 5.6%
Vomiting 5.6%
Pericardial Effusion 5.1%
Arrhythmia 4.6%
Dehydration 4.1%
Death 3.6%
Gastrointestinal Haemorrhage 3.6%
Nausea 3.6%
Vasculitis Cerebral 3.6%
Epistaxis 3.1%
Mouth Ulceration 3.1%
Pancytopenia 3.1%
Portal Vein Thrombosis 2.6%
Pulmonary Oedema 2.6%
Pyrexia 2.6%
Respiratory Failure 2.6%
Concomitant
Product Used For Unknown Indication 20.5%
Chronic Myeloid Leukaemia 10.4%
Drug Use For Unknown Indication 8.8%
Sickle Cell Anaemia 8.5%
Hypertension 8.2%
Acute Myeloid Leukaemia 6.8%
Pain 5.2%
Prophylaxis 4.6%
Iron Overload 4.4%
Myelofibrosis 3.6%
Essential Thrombocythaemia 3.3%
Myelodysplastic Syndrome 2.7%
Pustular Psoriasis 1.9%
Nausea 1.8%
Depression 1.7%
Osteoporosis 1.7%
Atrial Fibrillation 1.6%
Pulmonary Hypertension 1.5%
Stem Cell Transplant 1.5%
Diabetes Mellitus 1.4%
White Blood Cell Count Increased 10.4%
Death 9.9%
Vomiting 9.9%
Sickle Cell Anaemia With Crisis 9.7%
Thrombocytopenia 8.6%
Pneumonia 6.4%
Weight Decreased 6.0%
Rash 4.4%
White Blood Cell Count Decreased 4.4%
Drug Ineffective 4.0%
T-cell Lymphoma 3.3%
Tumour Lysis Syndrome 3.3%
Pyrexia 3.1%
Acute Myeloid Leukaemia 2.9%
Respiratory Failure 2.6%
Renal Failure Acute 2.4%
Nausea 2.2%
Pain In Extremity 2.2%
Renal Failure 2.2%
Oedema Peripheral 2.0%
Interacting
Sickle Cell Anaemia 18.8%
Hypertension 12.5%
Iron Overload 12.5%
Thrombosis Prophylaxis 12.5%
Convulsion 6.3%
Infection Prophylaxis 6.3%
Ischaemic Heart Disease Prophylaxis 6.3%
Platelet Count Increased 6.3%
Prophylaxis Against Gastrointestinal Ulcer 6.3%
Tachycardia 6.3%
Thalassaemia Beta 6.3%
Drug Interaction 20.0%
Liver Function Test Abnormal 20.0%
Swollen Tongue 20.0%
Transaminases Increased 20.0%
Weight Increased 20.0%