Folic Acid combined with Hydroxyurea

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Metabolic Acidosis Other Serious 77 Male 2/9/2006 Other Health Professional Canada
Primary
Concomitant
Wrong Drug Administered Other Serious 3/23/2006 Female 4/5/2006 Consumer United States
Primary
Secondary
Concomitant
Medication Error Other Serious 3/23/2006 Female 4/10/2006 Physician United States
Primary
Secondary
Concomitant
Medication Error Other Serious 3/23/2006 Female 4/20/2006 Physician United States
Primary
Secondary
Concomitant
Metabolic Acidosis Other Serious 6/17/2004 78 Male 4/21/2006 Other Health Professional Canada
Primary
Concomitant
Renal Failure Acute Hospitalization 4/12/2006 Female 86 lb 4/26/2006 Pharmacist United States
Primary
Concomitant
Tremor Other Serious 74 Male 291 lb 5/11/2006 United States
Primary
Secondary
Concomitant
Unintended Pregnancy Other Serious 1/1/2005 32 Female 2/27/2006 Physician United States
Primary
Concomitant
Unintended Pregnancy Other Serious 21 Female 2/27/2006 Physician United States
Primary
Concomitant
Tremor Other Serious 3/7/2006 74 Male 291 lb 5/19/2006 United States
Primary
Secondary
Concomitant
Wrong Drug Administered Other Serious 3/1/2006 Female 5/26/2006 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 3/7/2006 74 Male 291 lb 5/24/2006 United States
Primary
Secondary
Concomitant
Medication Error Other Serious 3/1/2006 Female 6/30/2006 Physician United States
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 3/1/2006 42 Female 8/7/2006 Physician United States
Primary
Concomitant
Faecaloma Other Serious 7/24/2006 29 Female 222 lb 8/18/2006 United States
Primary
Concomitant
Faecaloma Other Serious 7/24/2006 29 Female 222 lb 8/18/2006 United States
Primary
Concomitant
Vascular Calcification Life Threatening 10/15/2005 67 Male 183 lb 9/8/2006 United States
Primary
Concomitant
Vascular Calcification Life Threatening 10/15/2005 67 Male 183 lb 9/28/2006 United States
Primary
Concomitant
Renal Failure Hospitalization 9/29/2006 16 Female 10/19/2006 United States
Primary
Concomitant
Paraesthesia 5/11/2006 35 Male 8/10/2006 Consumer United States
Primary
Concomitant
Tinnitus 22 Female 8/10/2006 Pharmacist United States
Primary
Concomitant
Respiratory Failure Other Serious 9/25/2006 16 Female 132 lb 11/11/2006 United States
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 1/9/2006 77 Male 1/2/2007 Pharmacist United States
Primary
Concomitant
Swelling Face Other Serious 12/23/2006 78 Male 197 lb 12/27/2006 Physician United States
Primary
Concomitant
Urticaria Other Serious 12/23/2006 78 Male 197 lb 1/23/2007 Physician United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious 5/1/2006 25 Male 110 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 5/7/2007 Other Health Professional Italy
Primary
Secondary
Serum Ferritin Increased Other Serious 5/7/2007 Other Health Professional Italy
Primary
Secondary
Serum Ferritin Increased Other Serious Male 5/7/2007 Other Health Professional Italy
Primary
Secondary
Serum Ferritin Increased Other Serious Female 5/7/2007 Other Health Professional Italy
Primary
Secondary
Concomitant
Serum Ferritin Increased Other Serious 5/7/2007 Other Health Professional Italy
Primary
Secondary
Serum Ferritin Increased Other Serious 5/8/2007 Other Health Professional Italy
Primary
Secondary
Cholecystitis Acute Hospitalization 4/23/2007 Female 106 lb 5/16/2007 Other Health Professional United States
Primary
Concomitant
Treatment Noncompliance Death 42 Female 7/6/2007 Other Health Professional United States
Primary
Concomitant
Rash Hospitalization 8/24/2006 74 Male 8/22/2007 Physician United States
Primary
Concomitant
Skin Turgor Decreased Hospitalization 2/11/2007 82 Female 9/26/2007 Other Health Professional United States
Primary
Concomitant
Platelet Count Increased Hospitalization 17 Female 10/3/2007 Other Health Professional United States
Primary
Concomitant
Ultrasound Abdomen Abnormal Other Serious 4/9/2007 17 Female 10/11/2007 Other Health Professional United States
Primary
Concomitant
Lung Consolidation Other Serious 8/26/2007 17 Female 170 lb 11/26/2007 Physician United States
Primary
Concomitant
Skin Turgor Decreased Hospitalization 2/11/2007 82 Female 11/28/2007 Other Health Professional United States
Primary
Concomitant
Oedema Other Serious 1/10/2008 Male 170 lb 4/11/2008 Pharmacist United States
Primary
Concomitant
Leukaemia Death 3/25/2008 Female 4/14/2008 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 1/23/2008 33 Male 3/3/2008 Pharmacist United States
Primary
Concomitant
Headache 4/17/2008 Female 5/9/2008 Consumer United States
Primary
Concomitant
Headache 4/17/2008 Female 5/19/2008 Consumer United States
Primary
Concomitant
Leukaemia Death 3/25/2008 Female 5/28/2008 Pharmacist United States
Primary
Concomitant
Ventricular Dysfunction Other Serious 5/1/2006 Male 110 lb 6/27/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Aneurysm Life Threatening 9/1/2007 Female 126 lb 8/4/2008 Physician United States
Primary
Concomitant
Nausea 3/24/2008 86 Male 170 lb 11/3/2008 Consumer United States
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 81 Male 181 lb 12/23/2008 Physician Italy
Primary
Secondary
Concomitant
Death Death 4/7/2009 Female 190 lb 4/21/2009 Consumer United States
Primary
Concomitant
Portal Vein Thrombosis Other Serious 1/1/2008 5/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Sudden Death Death 4/7/2009 Female 190 lb 5/4/2009 Physician United States
Primary
Concomitant
Portal Vein Thrombosis Other Serious 1/1/2008 Male 245 lb 5/23/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Sickle Cell Anaemia With Crisis Other Serious 4/3/2009 Female 211 lb 6/16/2009 Consumer United States
Primary
Secondary
Concomitant
Death Death 5/29/2009 Female 140 lb 6/26/2009 Consumer United States
Primary
Concomitant
Sickle Cell Anaemia With Crisis Other Serious 4/3/2009 Female 211 lb 7/6/2009 Physician United States
Primary
Concomitant
Pulmonary Arterial Hypertension Death Female 140 lb 7/23/2009 Physician United States
Primary
Concomitant
Sickle Cell Anaemia With Crisis Hospitalization 7/4/2009 Female 181 lb 9/11/2009 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 8/10/2009 Female 9/23/2009 Physician United States
Primary
Concomitant
Pancytopenia Hospitalization 7/23/2009 Female 190 lb 10/1/2009 Physician United States
Primary
Secondary
Concomitant
Sickle Cell Anaemia With Crisis Hospitalization 7/4/2009 Female 181 lb 10/1/2009 Physician United States
Primary
Concomitant
Inflammatory Bowel Disease Other Serious 8/22/2007 Male 99 lb 10/1/2009 United States
Primary
Concomitant
Sickle Cell Anaemia With Crisis Hospitalization 5/18/2009 Female 198 lb 10/5/2009 Physician United States
Primary
Concomitant
Sickle Cell Anaemia With Crisis Hospitalization 5/18/2009 Female 198 lb 10/20/2009 Physician United States
Primary
Concomitant
Sleep Disorder Hospitalization 9/1/2009 Female 10/23/2009 Canada
Primary
Concomitant
Weight Bearing Difficulty Hospitalization 32 Female 10/19/2009 Other Health Professional Israel
Primary
Secondary
Concomitant
Sickle Cell Anaemia With Crisis Other Serious 8/1/2009 Female 143 lb 10/27/2009 United States
Primary
Concomitant
Sleep Disorder Hospitalization 9/1/2009 Female 10/29/2009 Canada
Primary
Concomitant
White Blood Cell Count Increased Other Serious 8/10/2009 Female 11/2/2009 Physician United States
Primary
Concomitant
Pericardial Effusion Other Serious 1/10/2008 Male 170 lb 11/4/2009 Physician United States
Primary
Concomitant
Sickle Cell Anaemia With Crisis Hospitalization 2/27/2009 Female 205 lb 11/17/2009 Physician United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 1/19/2007 Male 40 lb 11/25/2009 United States
Primary
Concomitant
Interacting
Viral Infection Other Serious 1/1/1995 Male 205 lb 12/2/2009 Other Health Professional United States
Primary
Concomitant
Sickle Cell Anaemia With Crisis Hospitalization 9/13/2009 Female 12/16/2009 United States
Primary
Concomitant
Urine Output Decreased Other Serious Male 137 lb 12/16/2009 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/14/2009 Female 102 lb 12/21/2009 Physician Korea, Republic Of
Primary
Concomitant
Osteonecrosis Other Serious Female 12/30/2009 Physician Colombia
Primary
Concomitant
Sleep Disorder Hospitalization 9/1/2009 Female 1/6/2010 Canada
Primary
Concomitant
Vascular Occlusion Other Serious Female 1/19/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/14/2009 Female 102 lb 1/27/2010 Physician Korea, Republic Of
Primary
Concomitant
Thrombocytopenia Hospitalization 1/14/2009 Female 102 lb 2/3/2010 Physician Korea, Republic Of
Primary
Concomitant
Thrombocytosis Death 1/1/2001 73 Female 2/12/2010 Belgium
Primary
Secondary
Visual Impairment Hospitalization Male 83 lb 3/1/2010 Physician United States
Primary
Concomitant
Sickle Cell Anaemia With Crisis Hospitalization 1/1/2010 Female 3/2/2010 Other Health Professional United States
Primary
Concomitant
Viral Infection Other Serious 1/1/1995 Male 205 lb 3/4/2010 Other Health Professional United States
Primary
Concomitant
Nausea Hospitalization Female 191 lb 3/15/2010 United States
Primary
Concomitant
Somnolence Hospitalization 1/30/2010 Female 3/17/2010 Physician United States
Primary
Concomitant
Vascular Occlusion Other Serious Female 3/19/2010 Physician United States
Primary
Concomitant
Somnolence Hospitalization 1/30/2010 47 Female 4/8/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2003 Female 80 lb 4/16/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2003 Female 80 lb 4/22/2010 Other Health Professional United States
Primary
Concomitant
Pulmonary Embolism Other Serious 3/10/2010 26 Female 123 lb 5/3/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2003 Female 80 lb 5/17/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2003 Female 80 lb 5/27/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2003 84 Female 80 lb 6/3/2010 United States
Primary
Concomitant
Malaise Hospitalization 2/25/2010 15 Male 86 lb 6/3/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2003 84 Female 80 lb 6/21/2010 United States
Primary
Concomitant
Lipase Increased Other Serious 4/1/2010 5 Female 30 lb 6/30/2010 Physician United States
Primary
Concomitant
Pneumonia Hospitalization Female 7/5/2010 United States
Primary
Concomitant
Sickle Cell Anaemia With Crisis Hospitalization 6/25/2010 22 Female 180 lb 7/7/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2003 84 Female 80 lb 7/21/2010 United States
Primary
Concomitant
Somnolence Other Serious 1/1/2009 51 Female 179 lb 7/22/2010 Consumer United States
Primary
Secondary
Concomitant
Sickle Cell Anaemia With Crisis Other Serious 2/1/2010 20 Female 130 lb 7/27/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2003 84 Female 80 lb 8/10/2010 United States
Primary
Concomitant
Splenic Infarction Other Serious 6/1/2010 45 Female 150 lb 8/12/2010 United States
Primary
Concomitant
Sight Disability Other Serious Female 8/23/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2003 84 Female 80 lb 9/1/2010 United States
Primary
Concomitant
Sickle Cell Anaemia With Crisis Hospitalization 6/25/2010 22 Female 180 lb 9/8/2010 Consumer United States
Primary
Concomitant
Pulmonary Hypertension Other Serious 3/12/2010 26 Female 144 lb 9/15/2010 United States
Primary
Secondary
Concomitant
Sight Disability Other Serious 5/1/2010 48 Female 150 lb 9/21/2010 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization Female 9/23/2010 United States
Primary
Concomitant
Pain In Extremity Hospitalization 8/25/2010 24 Female 9/28/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization Female 10/11/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2003 84 Female 80 lb 10/14/2010 Other Health Professional United States
Primary
Concomitant
Transaminases Increased Hospitalization Male 40 lb 10/18/2010 Physician United States
Primary
Concomitant
Transaminases Increased Other Serious Male 117 lb 10/19/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 9/1/2007 56 Female 75 lb 10/21/2010 Lawyer United States
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 7/20/2010 33 Female 10/21/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 7/28/2007 55 Female 75 lb 10/28/2010 Lawyer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2003 84 Female 80 lb 11/15/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2003 84 Female 80 lb 11/25/2010 Other Health Professional United States
Primary
Concomitant
Transaminases Increased Other Serious Male 37 lb 11/29/2010 United States
Primary
Concomitant
Headache Other Serious 9/1/2010 45 Female 156 lb 11/30/2010 United States
Primary
Concomitant
Stem Cell Transplant Other Serious 7/2/2010 5 Female 57 lb 11/30/2010 United States
Primary
Concomitant
Malignant Neoplasm Progression Hospitalization 2/25/2010 15 Male 86 lb 12/6/2010 United States
Primary
Concomitant
Malignant Neoplasm Progression Hospitalization 2/25/2010 15 Male 99 lb 12/8/2010 United States
Primary
Concomitant
Pneumonia Hospitalization Female 12/23/2010 United States
Primary
Concomitant
Transfusion Reaction Hospitalization 12/3/2010 73 Female 148 lb 12/24/2010 Physician United States
Primary
Secondary
Concomitant
Renal Function Test Abnormal Other Serious Male 37 lb 1/13/2011 Physician United States
Primary
Concomitant
Injection Site Pain 6/9/2010 60 Female 1/29/2011 Consumer United States
Primary
Concomitant
Contusion Other Serious 1/1/2003 84 Female 80 lb 1/31/2011 Other Health Professional United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 1/1/2003 84 Female 80 lb 2/4/2011 United States
Primary
Concomitant
Anaemia Other Serious 12/22/2008 27 Female 123 lb 2/7/2011 Physician United States
Primary
Concomitant
Intervertebral Disc Degeneration Other Serious 1/1/2003 84 Female 80 lb 2/18/2011 Other Health Professional United States
Primary
Concomitant
Tremor Other Serious Male 3/1/2011 Canada
Primary
Concomitant
Sickle Cell Anaemia With Crisis Other Serious 9/15/2009 27 Female 150 lb 3/11/2011 Other Health Professional United States
Primary
Concomitant
Dehydration Hospitalization 6/1/2010 3/15/2011 Physician United States
Primary
Concomitant
Haematocrit Decreased Hospitalization Female 3/24/2011 United States
Primary
Concomitant
Death Death Female 3/31/2011 Consumer United States
Primary
Concomitant
Death Death Female 4/1/2011 United States
Primary
Concomitant
Urinary Tract Infection Staphylococcal Other Serious 1/1/2003 84 Female 80 lb 4/6/2011 United States
Primary
Concomitant
Blindness Hospitalization 12/29/2010 12 Male 83 lb 4/6/2011 Other Health Professional United States
Primary
Concomitant
Death Death 3/24/2011 28 Female 284 lb 4/8/2011 Pharmacist United States
Primary
Concomitant
Oropharyngeal Pain Other Serious 1/1/1986 60 Female 138 lb 3/24/2011 Consumer United States
Primary
Concomitant
Abnormal Behaviour Other Serious 10/13/2010 19 Female 176 lb 4/13/2011 United States
Primary
Concomitant
Pharyngitis Streptococcal Hospitalization 1/1/1986 60 Female 138 lb 4/7/2011 Consumer United States
Primary
Concomitant
Pulmonary Thrombosis Other Serious 1/1/2008 31 Female 146 lb 5/2/2011 Consumer United States
Primary
Secondary
Concomitant
Transfusion Male 5/9/2011 Physician United States
Primary
Concomitant
Flatulence Other Serious 2/27/2010 80 Female 137 lb 5/20/2011 Physician New Zealand
Primary
Concomitant

Drug Data