Aspirin combined with Hydroxyurea

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Swelling Hospitalization 4/1/2005 Male 175 lb 2/1/2006 Consumer United States
Primary
Concomitant
Toxic Epidermal Necrolysis Death 74 Male 2/13/2006 Canada
Primary
Secondary
Concomitant
Renal Failure Death 1/18/2006 85 Male 2/28/2006 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Death 1/18/2006 85 Male 3/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Death 1/18/2006 85 Male 3/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Visual Disturbance Female 150 lb 4/4/2006 Consumer United States
Primary
Secondary
Concomitant
Rash Female 130 lb 4/4/2006 Consumer United States
Primary
Concomitant
Wrong Drug Administered Other Serious 3/23/2006 Female 4/5/2006 Consumer United States
Primary
Secondary
Concomitant
Medication Error Other Serious 3/23/2006 Female 4/10/2006 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/16/2004 Female 194 lb 4/14/2006 Physician United Kingdom
Primary
Concomitant
Medication Error Other Serious 3/23/2006 Female 4/20/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/16/2006 Male 4/19/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 74 Male 4/28/2006 Canada
Primary
Secondary
Concomitant
Petechiae Required Intervention 4/18/2006 80 Female 176 lb 5/1/2006 Physician United States
Primary
Concomitant
Throat Tightness 11/17/2005 Female 3/12/2006 Consumer United States
Primary
Concomitant
Wrong Drug Administered Other Serious 3/1/2006 Female 5/26/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting 1/1/2006 68 Female 128 lb 4/24/2006 United States
Primary
Concomitant
Cardiac Failure Other Serious 9/1/2005 75 Male 190 lb 5/3/2006 Physician Germany
Primary
Concomitant
Medication Error Other Serious 3/1/2006 Female 6/30/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/5/2006 61 Male 6/26/2006 Consumer United States
Primary
Secondary
Concomitant
Osteoporotic Fracture Hospitalization 3/1/2006 Male 7/28/2006 Consumer United States
Primary
Concomitant
Cardiac Failure Other Serious 9/1/2005 75 Male 190 lb 7/14/2006 Physician Germany
Primary
Concomitant
Nail Discolouration 3/21/2006 36 Female 198 lb 8/1/2006 Consumer United States
Primary
Concomitant
Mycosis Fungoides Other Serious 6/16/2004 Female 194 lb 8/3/2006 Physician United Kingdom
Primary
Concomitant
T-cell Lymphoma Other Serious Female 194 lb 8/3/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 7/31/2006 Male 118 lb 8/30/2006 Physician United States
Primary
Concomitant
Occult Blood Positive Required Intervention 1/14/2006 74 Female 109 lb 6/5/2006 Pharmacist United States
Primary
Secondary
Concomitant
Therapy Non-responder Other Serious 76 Female 10/9/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Therapy Non-responder Other Serious 76 Female 10/6/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Neurological Symptom Death 10/15/2006 Male 179 lb 10/18/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Therapy Non-responder Other Serious Female 194 lb 11/2/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Melaena Other Serious 3/15/1999 72 Male 169 lb 11/17/2006 Consumer United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 9/1/2006 80 Male 172 lb 11/21/2006 Consumer United States
Primary
Concomitant
Haemorrhage Other Serious 3/15/1999 Male 169 lb 12/5/2006 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Death 2/1/2002 82 Male 12/26/2006 Other Health Professional New Zealand
Primary
Secondary
Pyrexia 8/22/2006 Female 12/22/2006 Other Health Professional United States
Primary
Concomitant
Pneumonia Death 2/1/2002 82 Male 1/8/2007 Other Health Professional New Zealand
Primary
Secondary
Swelling Face Other Serious 12/23/2006 78 Male 197 lb 12/27/2006 Physician United States
Primary
Concomitant
Drug Ineffective Life Threatening 71 Female 1/19/2007 Turkey
Primary
Concomitant
Ventricular Fibrillation 71 Female 1/29/2007 Turkey
Primary
Concomitant
Ventricular Fibrillation 71 Female 1/29/2007 Turkey
Primary
Concomitant
T-cell Lymphoma Other Serious Female 194 lb 2/5/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Urticaria Other Serious 12/23/2006 78 Male 197 lb 1/23/2007 Physician United States
Primary
Concomitant
Lip Dry Other Serious 85 Female 98 lb 2/23/2006 United States
Primary
Concomitant
Pleural Effusion Other Serious 1/26/2007 76 Male 2/22/2007 Other Health Professional Italy
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/1/2007 86 Male 130 lb 7/3/2007 United States
Primary
Concomitant
Weight Decreased Other Serious 3/1/2007 86 Male 130 lb 7/6/2007 United States
Primary
Concomitant
Rash Erythematous Hospitalization 8/10/2007 81 Male 9/14/2007 Physician Switzerland
Primary
Concomitant
Palpitations Female 150 lb 10/4/2007 Other Health Professional United States
Primary
Concomitant
Drug Interaction Other Serious 67 Female 119 lb 10/5/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Interaction Other Serious 67 Female 119 lb 10/17/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Chronic Myeloid Leukaemia Other Serious 1/7/2004 Female 202 lb 10/12/2007 Physician United States
Primary
Concomitant
Peripheral Ischaemia Hospitalization 34 Male 10/19/2007 Physician United States
Primary
Secondary
Concomitant
Tenderness Hospitalization 34 Male 10/19/2007 Physician United States
Primary
Secondary
Concomitant
Peripheral Vascular Disorder Hospitalization 34 Male 10/20/2007 United States
Primary
Secondary
Concomitant
Pneumothorax Other Serious 2/19/2007 72 Male 11/13/2007 Other Health Professional Denmark
Primary
Secondary
Concomitant
Erythema Multiforme Other Serious 12/19/2006 84 Male 112 lb 12/10/2007 Physician Switzerland
Primary
Secondary
Concomitant
Rhonchi Hospitalization 57 Male 1/21/2008 Physician Turkey
Primary
Concomitant
Chest Pain Other Serious 1/1/2008 Female 1/31/2008 Other Health Professional United States
Primary
Concomitant
Chest Pain Other Serious 1/1/2008 Female 2/12/2008 Other Health Professional United States
Primary
Concomitant
Vanishing Bile Duct Syndrome Other Serious 69 Male 2/8/2008 United States
Primary
Concomitant
Treatment Failure Other Serious 59 Female 3/12/2008 Physician United Kingdom
Primary
Concomitant
Nasal Discomfort 1/3/2008 91 Female 104 lb 4/29/2008 Consumer United States
Primary
Concomitant
Irritability 6/1/2007 79 Female 5/1/2008 Consumer United States
Primary
Concomitant
Headache 4/17/2008 Female 5/19/2008 Consumer United States
Primary
Concomitant
Malignant Neoplasm Progression Hospitalization 3/16/2008 82 Male 6/23/2008 Other Health Professional United States
Primary
Concomitant
T-cell Lymphoma Other Serious Female 194 lb 7/10/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Syncope Other Serious Female 7/15/2008 Consumer United States
Primary
Concomitant
Pancreatitis Other Serious 4/1/2008 76 Male 157 lb 8/11/2008 Physician Germany
Primary
Concomitant
Tooth Infection Other Serious 1/1/2004 82 Female 141 lb 8/15/2008 Physician United States
Primary
Secondary
Concomitant
Angioedema Other Serious 10/4/2007 68 Male 9/2/2008 Austria
Primary
Concomitant
Ventricular Extrasystoles Other Serious 2/19/2007 73 Male 9/29/2008 Other Health Professional Denmark
Primary
Secondary
Concomitant
Pancreatitis Other Serious 4/1/2008 76 Male 157 lb 10/14/2008 Physician Germany
Primary
Secondary
Concomitant
T-cell Lymphoma Other Serious Female 194 lb 10/20/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Tooth Infection Other Serious 1/1/2004 79 Female 141 lb 10/21/2008 Physician United States
Primary
Secondary
Concomitant
Nausea 3/24/2008 86 Male 170 lb 11/3/2008 Consumer United States
Primary
Concomitant
Tremor Hospitalization 9/1/2008 79 Female 12/15/2008 Consumer Switzerland
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2008 84 Female 150 lb 12/30/2008 Consumer United States
Primary
Concomitant
Thrombocytopenia Life Threatening 84 Female 1/20/2009 Other Health Professional United States
Primary
Secondary
White Blood Cell Count Decreased Life Threatening 84 Female 1/15/2009 Physician United States
Primary
Concomitant
Vomiting Hospitalization 1/21/2009 Male 1/22/2009 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 1/29/2009 Male 200 lb 2/25/2009 United States
Primary
Secondary
Concomitant
Asthma Hospitalization 81 Female 9 lb 2/26/2009 Consumer United States
Primary
Concomitant
Ulcer Other Serious 2/10/2009 Male 3/17/2009 Physician Greece
Primary
Secondary
Death Death 4/7/2009 Female 190 lb 4/21/2009 Consumer United States
Primary
Concomitant
Respiratory Failure Death 3/23/2009 Male 140 lb 4/24/2009 Physician United States
Primary
Concomitant
Portal Vein Thrombosis Other Serious 1/1/2008 5/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Sudden Death Death 4/7/2009 Female 190 lb 5/4/2009 Physician United States
Primary
Concomitant
Portal Vein Thrombosis Other Serious 1/1/2008 Male 245 lb 5/23/2009 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/2/2007 60 Male 5/28/2009 Other Health Professional Australia
Primary
Concomitant
Gastrointestinal Haemorrhage Life Threatening 2/13/2008 70 Female 170 lb 5/29/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 4/5/2009 81 Male 179 lb 6/2/2009 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 7/1/2008 60 Female 6/11/2009 Other Health Professional Germany
Primary
Concomitant
Traumatic Brain Injury Hospitalization 2/5/2009 75 Female 163 lb 6/11/2009 Pharmacist United States
Primary
Secondary
Concomitant
Off Label Use Other Serious 7/15/2003 Female 135 lb 7/27/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 7/15/2003 Female 135 lb 8/14/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 3/1/2009 Female 145 lb 8/14/2009 United States
Primary
Concomitant
Cardiac Operation Hospitalization Male 10/23/2009 Canada
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 74 Male 10/26/2009 Pharmacist Canada
Primary
Secondary
Concomitant
Viral Infection Other Serious 1/1/1995 Male 205 lb 12/2/2009 Other Health Professional United States
Primary
Concomitant
Hospitalisation Other Serious 11/21/2009 62 Male 12/4/2009 Physician United States
Primary
Concomitant
Venous Insufficiency Other Serious 7/15/2003 Female 135 lb 12/17/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 11/3/2009 67 Female 1/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 10/1/2009 67 Female 1/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytosis Death 1/1/2001 73 Female 2/12/2010 Belgium
Primary
Secondary
Porphyria Non-acute Other Serious 81 Female 3/2/2010 Other Health Professional Morocco
Primary
Secondary
Sickle Cell Anaemia With Crisis Hospitalization 1/1/2010 Female 3/2/2010 Other Health Professional United States
Primary
Concomitant
Viral Infection Other Serious 1/1/2004 79 Female 141 lb 3/3/2010 Physician United States
Primary
Secondary
Concomitant
Viral Infection Other Serious 1/1/1995 Male 205 lb 3/4/2010 Other Health Professional United States
Primary
Concomitant
Viral Infection Other Serious 1/1/2004 79 Female 141 lb 3/10/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/11/2010 Male 234 lb 3/15/2010 United States
Primary
Secondary
Renal Failure Acute Other Serious 62 Male 198 lb 3/17/2010
Primary
Secondary
Malignant Tumour Excision Other Serious 1/11/2010 65 Female 145 lb 3/15/2010 United Kingdom
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 1/11/2010 65 Female 3/18/2010 United Kingdom
Primary
Secondary
Concomitant
Viral Infection Other Serious 1/1/2004 79 Female 141 lb 4/5/2010 Physician United States
Primary
Secondary
Concomitant
Transplant Other Serious Male 4/12/2010 United States
Primary
Concomitant
Viral Infection Other Serious 1/1/2004 79 Female 141 lb 4/20/2010 Physician United States
Primary
Secondary
Concomitant
Wound Drainage Hospitalization 3/22/2010 91 Female 124 lb 4/21/2010 Physician United States
Primary
Concomitant
Death Death Female 4/28/2010 Consumer United States
Primary
Concomitant
Death Death Female 5/4/2010 Consumer United States
Primary
Concomitant
Viral Infection Other Serious 9/1/2003 79 Female 141 lb 5/10/2010 Physician United States
Primary
Secondary
Concomitant
Wound Secretion Hospitalization 3/22/2010 91 Female 124 lb 4/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Disability 1/1/2002 63 Male 181 lb 5/11/2010 Physician Germany
Primary
Secondary
Concomitant
Respiratory Failure Death Female 5/11/2010 Other Health Professional United States
Primary
Concomitant
Wound Drainage Hospitalization 3/22/2010 91 Female 123 lb 5/13/2010 United States
Primary
Concomitant
Wound Drainage Hospitalization 3/22/2010 91 Female 123 lb 5/26/2010 United States
Primary
Concomitant
Wound Secretion Hospitalization 3/22/2010 91 Female 124 lb 5/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Secretion Hospitalization 3/22/2010 91 Female 127 lb 5/27/2010 Physician United States
Primary
Secondary
Concomitant
Wound Drainage Hospitalization 3/22/2010 91 Female 123 lb 6/3/2010 United States
Primary
Concomitant
Pneumonia Hospitalization 5/1/2010 80 Male 6/30/2010 United States
Primary
Concomitant
Pulmonary Arterial Hypertension Death Male 7/14/2010 Consumer United States
Primary
Concomitant
Wound Infection Hospitalization 3/22/2010 91 Female 124 lb 7/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Drainage Hospitalization 3/22/2010 91 Female 123 lb 7/16/2010 United States
Primary
Concomitant
Thrombocytopenia Life Threatening 12/7/2006 7/22/2010 Physician Germany
Primary
Secondary
Concomitant
Wound Infection Hospitalization 3/22/2010 91 Female 124 lb 7/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 3/22/2010 91 Female 123 lb 7/28/2010 United States
Primary
Concomitant
Pulmonary Arterial Hypertension Death Male 7/29/2010 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization 5/1/2010 80 Male 7/27/2010 Consumer United States
Primary
Concomitant
Wound Infection Hospitalization 3/22/2010 91 Female 124 lb 7/28/2010 Physician United States
Primary
Secondary
Concomitant
Incorrect Dose Administered Hospitalization 1/1/2010 52 Female 8/13/2010 Physician United States
Primary
Concomitant
Flushing 1/1/1990 47 Male 291 lb 8/27/2010 United States
Primary
Concomitant
Thrombocytosis Other Serious Female 8/30/2010 United States
Primary
Concomitant
Weight Increased Other Serious 3/1/2010 40 Female 130 lb 9/9/2010 Consumer Germany
Primary
Secondary
Concomitant
Interacting
Pulmonary Hypertension Other Serious Female 144 lb 9/13/2010 United States
Primary
Concomitant
Pulmonary Hypertension Other Serious 3/12/2010 26 Female 144 lb 9/15/2010 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2010 52 Female 148 lb 9/22/2010 Physician United States
Primary
Concomitant
Gastrointestinal Haemorrhage Life Threatening 2/13/2008 70 Female 170 lb 10/8/2010 Pharmacist Germany
Primary
Concomitant
Interacting
Transaminases Increased Other Serious 8/28/2009 14 Male 10/18/2010 Physician United States
Primary
Concomitant
Interacting
Suicide Attempt Other Serious 57 Male 175 lb 10/12/2010 United States
Primary
Concomitant
Gastrointestinal Haemorrhage Life Threatening 2/13/2008 70 Female 170 lb 10/19/2010 Other Health Professional Germany
Primary
Secondary
Concomitant

Drug Data