Exjade combined with Hydroxyurea

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Failure Acute Hospitalization 4/12/2006 Female 86 lb 4/26/2006 Pharmacist United States
Primary
Concomitant
Sickle Cell Anaemia With Crisis Hospitalization 4/18/2006 26 Male 5/20/2006 United States
Primary
Concomitant
Faecaloma Other Serious 7/24/2006 29 Female 222 lb 8/18/2006 United States
Primary
Concomitant
Weight Decreased Other Serious 7/31/2006 Male 118 lb 8/30/2006 Physician United States
Primary
Concomitant
Faecaloma Other Serious 7/24/2006 29 Female 222 lb 8/18/2006 United States
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 8/2/2006 18 Female 9/18/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Hospitalization 9/29/2006 16 Female 10/19/2006 United States
Primary
Concomitant
Paraesthesia 5/11/2006 35 Male 8/10/2006 Consumer United States
Primary
Concomitant
Tinnitus 22 Female 8/10/2006 Pharmacist United States
Primary
Concomitant
Respiratory Failure Other Serious 9/25/2006 16 Female 132 lb 11/11/2006 United States
Primary
Concomitant
Serum Ferritin Increased Other Serious 10/11/2006 12 Female 12/29/2006 Physician Brazil
Primary
Concomitant
Ventricular Hypertrophy Other Serious 5/1/2006 25 Male 110 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Swelling Face Other Serious 3/1/2007 30 Male 4/17/2007 Other Health Professional United States
Primary
Concomitant
Cholecystitis Acute Hospitalization 4/23/2007 Female 106 lb 5/16/2007 Other Health Professional United States
Primary
Concomitant
Treatment Noncompliance Death 42 Female 7/6/2007 Other Health Professional United States
Primary
Concomitant
Drug Interaction Other Serious 2/9/2007 7 Male 42 lb 7/31/2007 Physician United States
Primary
Secondary
Concomitant
Platelet Count Increased Hospitalization 17 Female 10/3/2007 Other Health Professional United States
Primary
Concomitant
Ultrasound Abdomen Abnormal Other Serious 4/9/2007 17 Female 10/11/2007 Other Health Professional United States
Primary
Concomitant
Serum Ferritin Increased Other Serious 10/11/2006 12 Female 4/1/2008 Physician Brazil
Primary
Concomitant
Serum Ferritin Increased Other Serious 10/11/2006 12 Female 4/4/2008 Physician Brazil
Primary
Concomitant
Vomiting Other Serious 1/23/2008 28 Male 149 lb 3/3/2008 Pharmacist United States
Primary
Concomitant
Treatment Noncompliance Other Serious 1/23/2008 31 Male 247 lb 3/3/2008 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 1/23/2008 33 Male 3/3/2008 Pharmacist United States
Primary
Concomitant
Ventricular Dysfunction Other Serious 5/1/2006 Male 110 lb 6/27/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Splenomegaly Other Serious 9/1/2008 68 Female 1/27/2009 Physician Australia
Primary
Concomitant
Ulcer Other Serious 2/10/2009 Male 3/17/2009 Physician Greece
Primary
Secondary
Sickle Cell Anaemia With Crisis Other Serious 4/3/2009 Female 211 lb 6/16/2009 Consumer United States
Primary
Secondary
Concomitant
Sickle Cell Anaemia With Crisis Other Serious 4/3/2009 Female 211 lb 7/6/2009 Physician United States
Primary
Concomitant
Transaminases Increased Other Serious 1/1/2006 Male 121 lb 7/13/2009 Consumer United States
Primary
Concomitant
Malignant Neoplasm Progression Death Male 157 lb 7/31/2009 United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious Male 8/13/2009 Physician Canada
Primary
Concomitant
Disease Progression Death 7/21/2009 Male 8/19/2009 United States
Primary
Concomitant
Transaminases Increased Hospitalization 8/7/2009 Male 64 lb 8/27/2009 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 65 Female 8/28/2009 Other Health Professional Saudi Arabia
Primary
Concomitant
White Blood Cell Count Increased Other Serious 8/10/2009 Female 9/23/2009 Physician United States
Primary
Concomitant
Inflammatory Bowel Disease Other Serious 8/22/2007 Male 99 lb 10/1/2009 United States
Primary
Concomitant
Wound Drainage Other Serious 6/12/2009 Male 10/7/2009 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 1/1/2008 Female 114 lb 10/20/2009 Other Health Professional United States
Primary
Concomitant
Sleep Disorder Hospitalization 9/1/2009 Female 10/23/2009 Canada
Primary
Concomitant
Cardiac Operation Hospitalization Male 10/23/2009 Canada
Primary
Concomitant
Sickle Cell Anaemia With Crisis Other Serious 8/1/2009 Female 143 lb 10/27/2009 United States
Primary
Concomitant
Sleep Disorder Hospitalization 9/1/2009 Female 10/29/2009 Canada
Primary
Concomitant
Salivary Hypersecretion Other Serious 9/22/2009 Female 161 lb 11/2/2009 United States
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 11/5/2008 Female 11/2/2009 United States
Primary
Secondary
White Blood Cell Count Increased Other Serious 8/10/2009 Female 11/2/2009 Physician United States
Primary
Concomitant
Wound Drainage Other Serious 6/12/2009 Male 11/3/2009 United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 1/19/2007 Male 40 lb 11/25/2009 United States
Primary
Concomitant
Interacting
Unresponsive To Stimuli Death Female 12/3/2009 United States
Primary
Concomitant
Influenza Other Serious 5/1/2009 Male 12/4/2009 Canada
Primary
Secondary
Concomitant
Sickle Cell Anaemia With Crisis Hospitalization 9/13/2009 Female 12/16/2009 United States
Primary
Concomitant
Urine Output Decreased Other Serious Male 137 lb 12/16/2009 Physician United States
Primary
Secondary
Concomitant
Reaction To Drug Excipients Other Serious 11/12/2009 Female 1/4/2010 United States
Primary
Concomitant
Sleep Disorder Hospitalization 9/1/2009 Female 1/6/2010 Canada
Primary
Concomitant
White Blood Cell Count Increased Other Serious Male 1/11/2010 Physician Canada
Primary
Concomitant
Treatment Noncompliance Hospitalization 19 Female 1/11/2010 Consumer United States
Primary
Secondary
Hepatic Function Abnormal Other Serious 11/5/2008 Female 1/15/2010 United States
Primary
Secondary
White Blood Cell Count Increased Other Serious 5/26/2009 Female 110 lb 1/15/2010 United States
Primary
Secondary
Concomitant
Vascular Occlusion Other Serious Female 1/19/2010 Physician United States
Primary
Concomitant
Wound Drainage Other Serious 2/1/2008 Male 2/15/2010 United States
Primary
Concomitant
Thrombocytopenia Other Serious Female 2/17/2010 Physician United States
Primary
Concomitant
Visual Impairment Hospitalization Male 83 lb 3/1/2010 Physician United States
Primary
Concomitant
Nausea Hospitalization Female 191 lb 3/15/2010 United States
Primary
Concomitant
Red Blood Cell Sickled Cells Present Hospitalization 2/22/2010 Male 3/16/2010 United States
Primary
Concomitant
Somnolence Hospitalization 1/30/2010 Female 3/17/2010 Physician United States
Primary
Concomitant
Vascular Occlusion Other Serious Female 3/19/2010 Physician United States
Primary
Concomitant
Influenza Other Serious 5/1/2009 Male 3/29/2010 Canada
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious Female 100 lb 4/8/2010 United States
Primary
Concomitant
Somnolence Hospitalization 1/30/2010 47 Female 4/8/2010 Physician United States
Primary
Concomitant
Sickle Cell Anaemia Other Serious 3/10/2010 46 Female 149 lb 4/9/2010 United States
Primary
Concomitant
Transplant Other Serious Male 4/12/2010 United States
Primary
Concomitant
Red Blood Cell Sickled Cells Present Other Serious 2/22/2010 15 Male 4/20/2010 United States
Primary
Concomitant
Pulmonary Embolism Other Serious 3/10/2010 26 Female 123 lb 5/3/2010 United States
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 8/2/2006 18 Female 5/5/2010 Other Health Professional United States
Primary
Concomitant
Malaise Hospitalization 2/25/2010 15 Male 86 lb 6/3/2010 United States
Primary
Concomitant
Influenza Other Serious 5/1/2009 57 Male 6/9/2010 Canada
Primary
Secondary
Concomitant
Lipase Increased Other Serious 4/1/2010 5 Female 30 lb 6/30/2010 Physician United States
Primary
Concomitant
Pneumonia Hospitalization Female 7/5/2010 United States
Primary
Concomitant
Thrombocytopenia Other Serious Female 100 lb 7/6/2010 United States
Primary
Concomitant
Sickle Cell Anaemia With Crisis Hospitalization Male 7/9/2010 United States
Primary
Concomitant
Joint Sprain Death 1/18/2010 60 Male 7/19/2010 Canada
Primary
Concomitant
Sickle Cell Anaemia With Crisis Other Serious 2/1/2010 20 Female 130 lb 7/27/2010 United States
Primary
Concomitant
Tooth Extraction Hospitalization Female 7/28/2010 Canada
Primary
Secondary
Concomitant
Splenic Infarction Other Serious 6/1/2010 45 Female 150 lb 8/12/2010 United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious Male 8/13/2010 Physician Canada
Primary
Concomitant
Sight Disability Other Serious Female 8/23/2010 United States
Primary
Concomitant
Weight Increased Other Serious 3/1/2010 40 Female 130 lb 9/9/2010 Consumer Germany
Primary
Secondary
Concomitant
Interacting
Pulmonary Hypertension Other Serious Female 144 lb 9/13/2010 United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2009 76 Male 9/13/2010 Physician Canada
Primary
Concomitant
Pulmonary Hypertension Other Serious 3/12/2010 26 Female 144 lb 9/15/2010 United States
Primary
Secondary
Concomitant
Sight Disability Other Serious 5/1/2010 48 Female 150 lb 9/21/2010 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization Female 9/23/2010 United States
Primary
Concomitant
Serum Ferritin Increased Other Serious 1/9/2009 79 Female 129 lb 9/27/2010 Pharmacist United States
Primary
Concomitant
Pain In Extremity Hospitalization 8/25/2010 24 Female 9/28/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization Female 10/11/2010 United States
Primary
Concomitant
Transaminases Increased Hospitalization Male 40 lb 10/18/2010 Physician United States
Primary
Concomitant
Transaminases Increased Other Serious 8/28/2009 14 Male 10/18/2010 Physician United States
Primary
Concomitant
Interacting
Transaminases Increased Other Serious Male 117 lb 10/19/2010 Physician United States
Primary
Concomitant
Staphylococcal Infection Other Serious 7/20/2010 33 Female 10/21/2010 Physician United States
Primary
Concomitant
Dysgeusia Hospitalization Male 10/28/2010 Canada
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2009 76 Male 11/4/2010 Physician Canada
Primary
Concomitant
Salivary Hypersecretion Other Serious 9/22/2009 40 Female 161 lb 11/17/2010 United States
Primary
Secondary
Concomitant
Dysgeusia Hospitalization Male 11/25/2010 Canada
Primary
Concomitant
Transaminases Increased Other Serious Male 37 lb 11/29/2010 United States
Primary
Concomitant
Somnolence Hospitalization Male 11/30/2010 Physician United States
Primary
Concomitant
Headache Other Serious 9/1/2010 45 Female 156 lb 11/30/2010 United States
Primary
Concomitant
Stem Cell Transplant Other Serious 7/2/2010 5 Female 57 lb 11/30/2010 United States
Primary
Concomitant
Sickle Cell Anaemia With Crisis Other Serious 4/20/2006 35 Female 176 lb 11/30/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2009 76 Male 12/3/2010 Physician Canada
Primary
Concomitant
Malignant Neoplasm Progression Hospitalization 2/25/2010 15 Male 86 lb 12/6/2010 United States
Primary
Concomitant
Malignant Neoplasm Progression Hospitalization 2/25/2010 15 Male 99 lb 12/8/2010 United States
Primary
Concomitant
Premature Baby Other Serious 10/3/2010 Male 12/23/2010 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization Female 12/23/2010 United States
Primary
Concomitant
Premature Labour Other Serious 3/10/2010 21 Female 123 lb 12/24/2010 United States
Primary
Concomitant
Somnolence Hospitalization Male 12/24/2010 Other Health Professional United States
Primary
Concomitant
Cerebral Infarction Other Serious 12/16/2010 9 Male 65 lb 1/5/2011 Other Health Professional United States
Primary
Concomitant
Abdominal Discomfort Hospitalization Male 1/7/2011 Canada
Primary
Concomitant
Cerebrovascular Accident Other Serious 12/16/2010 9 Male 65 lb 1/13/2011 Consumer United States
Primary
Concomitant
Renal Function Test Abnormal Other Serious Male 37 lb 1/13/2011 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization Male 191 lb 1/19/2011 United States
Primary
Concomitant
Headache Other Serious 12/16/2010 9 Male 65 lb 2/2/2011 Consumer United States
Primary
Concomitant
Anaemia Other Serious 12/22/2008 27 Female 123 lb 2/7/2011 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 12/16/2010 9 Male 65 lb 2/2/2011 United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 8/9/2010 17 Female 130 lb 2/17/2011 Other Health Professional United States
Primary
Concomitant
Fall Other Serious Male 2/22/2011 United States
Primary
Concomitant
Tremor Other Serious Male 3/1/2011 Canada
Primary
Concomitant
Sickle Cell Anaemia With Crisis Other Serious 9/15/2009 27 Female 150 lb 3/11/2011 Other Health Professional United States
Primary
Concomitant
Dehydration Hospitalization 6/1/2010 3/15/2011 Physician United States
Primary
Concomitant
Diarrhoea Hospitalization 1/19/2011 83 Male 104 lb 3/15/2011 Consumer United States
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 3/10/2010 21 Female 123 lb 3/17/2011 Consumer United States
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 10/3/2010 Male 3/17/2011 United States
Primary
Concomitant
Haematocrit Decreased Hospitalization Female 3/24/2011 United States
Primary
Concomitant
Death Death Female 3/31/2011 Consumer United States
Primary
Concomitant
Death Death Female 4/1/2011 United States
Primary
Concomitant
Blindness Hospitalization 12/29/2010 12 Male 83 lb 4/6/2011 Other Health Professional United States
Primary
Concomitant
Death Death 3/24/2011 28 Female 284 lb 4/8/2011 Pharmacist United States
Primary
Concomitant
Drug Intolerance Male 4/20/2011 Physician Canada
Primary
Secondary
Concomitant
Abnormal Behaviour Other Serious 10/13/2010 19 Female 176 lb 4/13/2011 United States
Primary
Concomitant
Acute Leukaemia Death Male 160 lb 4/28/2011 United States
Primary
Concomitant
Fall Other Serious 1/19/2011 83 Male 104 lb 5/5/2011 United States
Primary
Concomitant
Systemic Lupus Erythematosus Hospitalization Male 5/6/2011 United States
Primary
Concomitant
Muscle Spasms Other Serious Male 203 lb 5/6/2011 Physician United States
Primary
Concomitant
Acute Myeloid Leukaemia Death Male 158 lb 5/13/2011 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 12/16/2008 70 Male 205 lb 6/4/2011 Australia
Primary
Concomitant
Clostridium Difficile Colitis Hospitalization 6/1/2007 34 Female 150 lb 6/8/2011 United States
Primary
Concomitant
Oedema Peripheral Other Serious Male 6/14/2011 Canada
Primary
Concomitant
Nuclear Magnetic Resonance Imaging Abnormal Death 9/14/2006 80 Male 134 lb 6/17/2011 United States
Primary
Concomitant
Arthralgia Other Serious Female 6/22/2011 United States
Primary
Concomitant
Leukocytosis Other Serious 3/22/2011 Male 185 lb 6/22/2011 Physician Germany
Primary
Concomitant
Pain Hospitalization Male 257 lb 6/30/2011 Physician United States
Primary
Concomitant
Rales Other Serious 12/1/2010 36 Male 7/6/2011 Consumer United States
Primary
Concomitant

Drug Data