Temozolomide



Indications and Reactions:

Role Indications Reactions
Primary
Glioblastoma Multiforme 26.4%
Glioblastoma 16.0%
Prophylaxis 9.8%
Product Used For Unknown Indication 6.9%
Metastatic Malignant Melanoma 6.3%
Ovarian Cancer 5.4%
Drug Use For Unknown Indication 5.1%
Acute Myeloid Leukaemia 4.5%
Anaplastic Astrocytoma 2.8%
Glioma 2.7%
Medulloblastoma 1.9%
Malignant Melanoma 1.9%
Antifungal Prophylaxis 1.8%
Malignant Glioma 1.8%
Neoplasm 1.8%
Pain 1.1%
Brain Neoplasm Malignant 1.1%
Brain Neoplasm 0.9%
Nausea 0.9%
Routine Health Maintenance 0.8%
Thrombocytopenia 14.9%
White Blood Cell Count Decreased 14.9%
Vomiting 14.1%
Platelet Count Decreased 8.0%
Pulmonary Embolism 5.8%
Pyrexia 5.3%
Pneumonia 5.2%
Urinary Tract Infection 4.4%
Pancytopenia 3.9%
Weight Decreased 2.9%
Lymphopenia 2.5%
Sepsis 2.5%
White Blood Cell Count Increased 2.4%
Febrile Neutropenia 2.3%
Lymphocyte Count Decreased 2.2%
Disease Progression 1.9%
Convulsion 1.8%
Somnolence 1.8%
Deep Vein Thrombosis 1.6%
Nausea 1.5%
Secondary
Prophylaxis 31.1%
Glioblastoma Multiforme 18.1%
Glioblastoma 10.6%
Anaplastic Astrocytoma 8.2%
Drug Use For Unknown Indication 7.9%
Product Used For Unknown Indication 6.9%
Antifungal Prophylaxis 4.9%
Metastatic Malignant Melanoma 1.4%
Brain Stem Glioma 1.4%
Medulloblastoma 1.4%
Brain Neoplasm Malignant 1.2%
Urinary Tract Infection 1.0%
Glioma 0.8%
Neoplasm 0.8%
Central Nervous System Lymphoma 0.8%
Epilepsy 0.8%
Diabetes Mellitus 0.7%
Gliosarcoma 0.7%
Hypothyroidism 0.7%
Constipation 0.7%
White Blood Cell Count Decreased 34.9%
Thrombocytopenia 7.9%
Vomiting 6.5%
White Blood Cell Count Increased 4.4%
Radiation Necrosis 4.1%
Pulmonary Embolism 4.0%
Pyrexia 4.0%
Urinary Tract Infection 3.4%
Convulsion 3.1%
Xeroderma 3.1%
Neutropenia 3.0%
Nausea 2.8%
Protein Total Decreased 2.8%
Purpura 2.8%
Lymphocyte Count Decreased 2.4%
Upper Respiratory Tract Inflammation 2.3%
Weight Decreased 2.3%
Death 2.2%
Tumour Haemorrhage 2.0%
Overdose 1.9%
Concomitant
Glioblastoma Multiforme 19.8%
Glioblastoma 14.4%
Drug Use For Unknown Indication 13.5%
Product Used For Unknown Indication 11.4%
Metastatic Malignant Melanoma 6.8%
Rhabdomyosarcoma 4.6%
Sarcoma 3.9%
Convulsion 3.6%
Glioma 2.6%
Neuroblastoma 2.6%
Hypertension 2.1%
Sarcoma Metastatic 2.1%
Premedication 1.8%
Anaplastic Astrocytoma 1.6%
Colorectal Cancer 1.6%
Oligodendroglioma 1.6%
Schizophrenia 1.6%
Brain Neoplasm 1.5%
Brain Oedema 1.5%
Complex Partial Seizures 1.4%
Malignant Glioma 9.4%
Epilepsy 8.0%
Pulmonary Embolism 8.0%
Thrombocytopenia 8.0%
Optic Neuropathy 6.5%
Vomiting 6.5%
Angina Unstable 5.8%
Pneumonia 5.1%
Tubulointerstitial Nephritis 5.1%
Convulsion 4.3%
Neoplasm Malignant 4.3%
Cerebral Haemorrhage 3.6%
Death 3.6%
Disease Progression 3.6%
Large Intestine Perforation 3.6%
Drug Eruption 2.9%
Loss Of Consciousness 2.9%
Oral Candidiasis 2.9%
Rash 2.9%
Tumour Lysis Syndrome 2.9%
Interacting
Glioblastoma Multiforme 19.3%
Urinary Tract Infection 15.1%
Coordination Abnormal 10.1%
Hemiparesis 10.1%
Oligodendroglioma 10.1%
Product Used For Unknown Indication 10.1%
Drug Use For Unknown Indication 8.4%
Status Epilepticus 4.2%
Glioblastoma 3.4%
Astrocytoma 1.7%
Convulsion 1.7%
Deep Vein Thrombosis 1.7%
Mixed Oligo-astrocytoma 1.7%
Prophylaxis Of Nausea And Vomiting 1.7%
Hypercholesterolaemia 0.8%
Thrombocytopenia 45.0%
Ophthalmoplegia 15.0%
Epilepsy 10.0%
Liver Function Test Abnormal 10.0%
Paralysis 10.0%
Hepatic Failure 5.0%
White Blood Cell Count Decreased 5.0%