Levetiracetam combined with Temozolomide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Liver Disorder Hospitalization 11/2/2007 Female 1/10/2008 Other Health Professional France
Primary
Secondary
Thrombocytopenia Hospitalization 11/10/2006 75 Female 2/19/2008 Physician Turkey
Primary
Secondary
Tremor Other Serious 11/10/2006 75 Female 2/29/2008 Physician Turkey
Primary
Secondary
Hepatitis Cholestatic Hospitalization 11/15/2007 Female 3/7/2008 Other Health Professional France
Primary
Secondary
Staphylococcal Sepsis Other Serious 1/1/2006 69 Male 7/14/2008 Physician United States
Primary
Secondary
Concomitant
Splenic Infarction Other Serious 2/1/2008 52 Male 170 lb 7/21/2008 Physician United States
Primary
Secondary
Concomitant
Splenic Infarction Hospitalization 52 Male 9/17/2008 United States
Primary
Secondary
Stevens-johnson Syndrome Hospitalization 2/16/2008 50 Male 2/4/2009 Physician France
Primary
Secondary
Concomitant
Wound Infection Hospitalization 3/9/2009 Male 171 lb 3/12/2009 Other Health Professional United States
Primary
Concomitant
Pancreatitis Hospitalization 4/24/2009 Male 226 lb 5/22/2009 Physician United States
Primary
Concomitant
Rash Pruritic Hospitalization 52 Male 9/18/2009 Other Health Professional United States
Primary
Secondary
Drug Hypersensitivity Hospitalization 52 Male 9/18/2009 Other Health Professional United States
Primary
Secondary
Rash Pruritic Hospitalization 52 Male 9/18/2009 United States
Primary
Secondary
Vomiting Hospitalization 11/17/2009 46 Male 209 lb 1/25/2010 Physician United States
Primary
Concomitant
Hepatic Function Abnormal Other Serious 9/7/2009 63 Male 173 lb 3/24/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Eruption Hospitalization 9/17/2009 72 Female 165 lb 4/19/2010 Other Health Professional Austria
Primary
Secondary
Concomitant
Staphylococcal Sepsis Other Serious 1/1/2006 69 Male 6/10/2010 Physician United States
Primary
Secondary
Concomitant
Sepsis Other Serious 69 Female 6/15/2010 United States
Primary
Secondary
Somnolence Other Serious 46 Female 6/18/2010 Other Health Professional United States
Primary
Concomitant
Neutrophil Count Increased Hospitalization 1/11/2010 51 Male 168 lb 7/16/2010 Physician Belgium
Primary
Secondary
Concomitant
Large Intestine Perforation Hospitalization 1/11/2010 51 Male 168 lb 7/19/2010 Physician Belgium
Primary
Secondary
Concomitant
Large Intestine Perforation Hospitalization 1/11/2010 51 Male 168 lb 7/20/2010 Physician Belgium
Primary
Secondary
Concomitant
Hepatitis Fulminant Hospitalization 6/12/2010 37 Female 163 lb 7/16/2010 Physician Chile
Primary
Secondary
Concomitant
Large Intestine Perforation Hospitalization 1/11/2010 51 Male 168 lb 7/27/2010 Consumer United States
Primary
Secondary
Concomitant
Somnolence Other Serious 46 Female 8/5/2010
Primary
Secondary
Neurological Decompensation Hospitalization 7/22/2010 54 Male 8/9/2010 Physician Spain
Primary
Secondary
Concomitant
Thrombosis Other Serious 6/26/2010 72 Male 8/12/2010 Physician United States
Primary
Secondary
Concomitant
Large Intestine Perforation Hospitalization 1/11/2010 51 Male 168 lb 8/23/2010 Consumer United States
Primary
Secondary
Concomitant
Large Intestine Perforation Hospitalization 1/11/2010 51 Male 168 lb 8/24/2010 Consumer United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 6/26/2010 72 Male 8/20/2010 Physician United States
Primary
Secondary
Concomitant
Venous Occlusion Other Serious 6/25/2010 72 Male 183 lb 9/24/2010 Physician United States
Primary
Secondary
Concomitant
Product Substitution Issue Other Serious 30 Female 10/8/2010 Other Health Professional United States
Primary
Concomitant
Thrombosis Other Serious 6/25/2010 72 Male 183 lb 10/21/2010 Physician United States
Primary
Secondary
Concomitant
Pyrexia Life Threatening 55 Female 12/13/2010 Pharmacist United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/23/2010 63 175 lb 12/6/2010 Physician Spain
Primary
Concomitant
Pulmonary Embolism Hospitalization 11/23/2010 63 175 lb 12/30/2010 Physician Spain
Primary
Concomitant
Neutropenia Hospitalization 4/11/2010 69 Male 300 lb 2/24/2011 Consumer United States
Primary
Secondary
Concomitant
Convulsion Hospitalization 12/16/2010 53 Male 183 lb 2/25/2011 Physician Italy
Primary
Secondary
Concomitant
Cholecystitis Hospitalization 12/31/2010 52 Male 183 lb 3/8/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Oedema Death 71 Female 125 lb 3/28/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Atelectasis Death 71 Female 125 lb 4/4/2011 Physician United States
Primary
Secondary
Concomitant
Blood Alkaline Phosphatase Increased 4/30/2010 70 Male 7/8/2010 Physician United States
Primary
Secondary
Epilepsy Hospitalization 5/9/2011 39 Male 198 lb 5/25/2011 Physician Spain
Primary
Secondary
Concomitant
Atelectasis Death 71 Female 125 lb 5/27/2011 Physician United States
Primary
Secondary
Concomitant
Pancytopenia Other Serious 71 Female 125 lb 5/25/2011 Physician United States
Primary
Secondary
Concomitant
Large Intestine Perforation Hospitalization 1/11/2010 51 Male 168 lb 6/8/2011 Physician United States
Primary
Secondary
Concomitant
Cold Agglutinins Positive Other Serious 4/7/2011 46 Male 175 lb 6/13/2011 Physician Australia
Primary
Concomitant
Neutropenia Other Serious 6/6/2011 68 Female 140 lb 6/20/2011 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 4/7/2011 46 Male 175 lb 7/7/2011 Physician Australia
Primary
Concomitant
Herpes Simplex Other Serious 4/7/2011 46 Male 175 lb 7/19/2011 Physician Australia
Primary
Concomitant
Recurrent Cancer Other Serious 50 Female 174 lb 7/26/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased 65 Male 7/22/2011 Physician United States
Primary
Secondary
Herpes Simplex Other Serious 4/7/2011 46 Male 175 lb 9/14/2011 Physician Australia
Primary
Concomitant
Muscular Weakness Hospitalization 9/27/2011 67 Female 154 lb 10/12/2011 Physician Australia
Primary
Concomitant
Drug Eruption Other Serious 10/21/2011 Physician United States
Primary
Concomitant
Weight Increased Other Serious 10/24/2011 Physician Spain
Primary
Concomitant
Skin Infection Hospitalization 12/4/2009 45 Male 162 lb 10/24/2011 Belgium
Primary
Concomitant
Drug Interaction Other Serious 71 Female 10/25/2011 Other Health Professional United States
Primary
Concomitant
Interacting
Cerebral Infarction Hospitalization 10/18/2011 59 Male 165 lb 10/26/2011 United States
Primary
Secondary
Concomitant
Convulsion Hospitalization 3/15/2011 52 Female 135 lb 11/1/2011 Physician United States
Primary
Secondary
Cognitive Disorder Hospitalization 67 Female 154 lb 11/4/2011 Physician Australia
Primary
Concomitant
Tubulointerstitial Nephritis Other Serious 1/1/2011 45 Male 11/23/2011 Physician United States
Primary
Concomitant
Cognitive Disorder Hospitalization 9/27/2011 67 Female 154 lb 11/21/2011 Physician Australia
Primary
Concomitant
Haematuria Hospitalization 10/19/2011 59 Male 165 lb 12/5/2011 United States
Primary
Secondary
Concomitant
Epilepsy Other Serious 71 Female 12/6/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Lactic Acid Increased Hospitalization 12/8/2011 United States
Primary
Concomitant
Interacting
Renal Failure Acute Other Serious 45 Male 12/12/2011 Other Health Professional
Primary
Concomitant
Neoplasm Progression Death 75 Female 12/12/2011 Other Health Professional Italy
Primary
Secondary
Neoplasm Progression Other Serious 72 Female 12/12/2011 Physician Italy
Primary
Secondary
Neoplasm Progression Death 71 Male 12/12/2011 Physician Italy
Primary
Secondary
Neoplasm Progression Death 75 Female 12/13/2011 Other Health Professional Italy
Primary
Secondary
Neoplasm Progression Death 48 Male 12/13/2011 Physician Italy
Primary
Secondary
Neoplasm Progression Death 33 Male 12/13/2011 Other Health Professional Italy
Primary
Secondary
Convulsion Other Serious 46 Male 12/13/2011 Physician Italy
Primary
Secondary
Neoplasm Progression Other Serious 63 Female 12/13/2011 Other Health Professional Italy
Primary
Secondary
Neoplasm Progression Death 50 Male 12/13/2011 Other Health Professional Italy
Primary
Secondary
Neoplasm Progression Death 44 Male 12/13/2011 Physician Italy
Primary
Secondary
Cognitive Disorder Hospitalization 9/27/2011 67 Female 154 lb 12/5/2011 Physician Australia
Primary
Concomitant
Brain Oedema Hospitalization 11/12/2011 56 Male 168 lb 12/30/2011 Other Health Professional Spain
Primary
Secondary
Concomitant
Intracranial Tumour Haemorrhage Hospitalization 11/12/2011 56 Male 168 lb 12/23/2011 Physician Spain
Primary
Secondary
Concomitant
Convulsion Hospitalization 1/14/2012 36 Male 197 lb 1/17/2012 Other Health Professional United States
Primary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 1/11/2010 51 Male 168 lb 1/25/2012 Belgium
Primary
Secondary
Concomitant
Aphasia Hospitalization 1/14/2012 36 Male 197 lb 1/23/2012 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Other Serious 2/13/2012 United States
Primary
Concomitant
Activated Partial Thromboplastin Time Prolonged Required Intervention 71 Female 2/7/2012 Other Health Professional United States
Primary
Secondary
Concomitant
No Therapeutic Response Other Serious 45 Male 2/17/2012 Other Health Professional United States
Primary
Concomitant
Tubulointerstitial Nephritis Other Serious 4/1/2011 45 Male 2/29/2012 United States
Primary
Secondary
Concomitant
Cerebral Haemorrhage Life Threatening 12/22/2011 39 Male 168 lb 3/22/2012 Physician Australia
Primary
Concomitant
Leukocyturia Other Serious 45 Male 3/22/2012 Other Health Professional United States
Primary
Concomitant
Tubulointerstitial Nephritis Other Serious 45 Male 3/23/2012 Other Health Professional United States
Primary
Concomitant
Brain Oedema Hospitalization 11/12/2011 56 Male 168 lb 3/22/2012 Other Health Professional Spain
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 45 Male 3/27/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 45 Male 3/27/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Balance Disorder Other Serious 45 Male 4/4/2012 Other Health Professional United States
Primary
Concomitant
Tubulointerstitial Nephritis Other Serious 45 Male 4/4/2012 Other Health Professional United States
Primary
Concomitant
Leukoencephalopathy Hospitalization 3/10/2011 59 Male 185 lb 4/19/2012 France
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 45 Male 4/26/2012 Physician United States
Primary
Secondary
Leukoencephalopathy Hospitalization 3/10/2011 59 Male 4/24/2012 Physician France
Primary
Secondary
Concomitant
Gait Disturbance Other Serious 4/1/2012 265 lb 4/30/2012 Consumer Germany
Primary
Secondary
Concomitant
Leukoencephalopathy Hospitalization 3/10/2011 59 Male 185 lb 5/2/2012 France
Primary
Secondary
Concomitant
Leukoencephalopathy Hospitalization 3/10/2011 59 Male 185 lb 5/3/2012 Physician France
Primary
Secondary
Concomitant
Tumour Haemorrhage Hospitalization 11/12/2011 56 Male 168 lb 5/4/2012 Other Health Professional Spain
Primary
Secondary
Concomitant
Leukoencephalopathy Hospitalization 3/10/2011 59 Male 185 lb 5/9/2012 France
Primary
Secondary
Concomitant
Leukoencephalopathy Life Threatening 3/10/2011 59 Male 185 lb 5/11/2012 France
Primary
Secondary
Concomitant
Syncope Hospitalization 5/9/2012 56 Male 5/25/2012 Physician United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 3/10/2011 59 Male 5/14/2012 Physician France
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 5/2/2012 Male 183 lb 5/23/2012 Physician Australia
Primary
Concomitant
Peritonitis Hospitalization 5/6/2012 60 Female 132 lb 6/1/2012 Physician Germany
Primary
Secondary
Concomitant
Peritonitis Hospitalization 5/6/2012 60 Female 132 lb 6/6/2012 Physician Germany
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Death 3/13/2012 61 Male 6/21/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Partial Seizures Other Serious 4/1/2012 Male 265 lb 7/13/2012 Consumer Germany
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 5/2/2012 8/3/2012 Australia
Primary
Concomitant
Renal Failure Other Serious 45 Male 7/20/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Epilepsy Hospitalization 5/9/2011 39 Male 198 lb 11/7/2012 Physician Es
Primary
Secondary
Pulmonary Embolism Hospitalization 5/2/2012 55 Male 183 lb 11/8/2013 Au
Primary
Concomitant
Pneumonitis Life Threatening 3/21/2012 9/28/2012 Physician Au
Primary
Secondary
Concomitant
Pneumonitis Life Threatening 3/21/2012 32 Female 158 lb 8/19/2013 Physician Au
Primary
Concomitant
Tubulointerstitial Nephritis Other Serious 45 Male 8/29/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Convulsion Hospitalization 12/1/2011 63 Male 149 lb 9/20/2012 Physician De
Primary
Secondary
Concomitant
Convulsion Hospitalization 10/1/2012 63 Male 148 lb 10/1/2012 Physician Country Not Specified
Primary
Secondary
Concomitant
Meningitis Hospitalization 8/28/2012 52 Male 245 lb 10/31/2012 Consumer Us
Primary
Secondary
Concomitant
Wound Infection Hospitalization 10/24/2012 52 Male 210 lb 12/7/2012 Consumer Be
Primary
Concomitant
Epilepsy Hospitalization 5/9/2011 39 Male 198 lb 11/22/2012 Consumer Gb
Primary
Secondary
Infection Hospitalization 6/25/2011 79 Male 170 lb 11/26/2012 Consumer Us
Primary
Secondary
Concomitant
Epilepsy Hospitalization 5/9/2011 39 Male 384 lb 11/29/2012 Physician Es
Primary
Secondary
Delirium Hospitalization 2/17/2010 32 Female 121 lb 12/4/2012 Physician Au
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 8/27/2012 66 Male 229 lb 12/6/2012 Physician De
Primary
Secondary
Concomitant
Urosepsis Hospitalization 11/11/2012 64 Female 130 lb 12/14/2012 Consumer Us
Primary
Secondary
Concomitant
Neurological Decompensation Hospitalization 4/13/2011 56 Male 172 lb 12/10/2012 Physician De
Primary
Secondary
Concomitant
Vasogenic Cerebral Oedema Hospitalization 7/24/2009 52 Female 179 lb 12/18/2012 Physician Us
Primary
Secondary
Concomitant
Thrombosis Death 6/18/2010 72 Male 183 lb 1/15/2013 Consumer Us
Primary
Secondary
Concomitant
Nausea Other Serious 9/7/2011 47 Male 174 lb 8/1/2013 Physician De
Primary
Secondary
Concomitant
Sepsis Hospitalization 1/24/2013 42 Female 185 lb 6/4/2013 Physician Us
Primary
Concomitant
Thrombocytopenia Other Serious NotSpecified 3/19/2013 Physician Nl
Primary
Concomitant
Large Intestine Perforation Death 3/12/2013 55 Male 150 lb 4/18/2013 Physician Es
Primary
Secondary
Concomitant
Thrombocytopenia NotSpecified 4/15/2013 Physician At
Primary
Concomitant
General Physical Health Deterioration Death 5/13/2011 62 Female 181 lb 4/16/2013 Consumer De
Primary
Secondary
Concomitant
Stupor Life Threatening 2012 73 Male 5/8/2013 Physician Country Not Specified
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization Female 115 lb 5/27/2013 Physician Fr
Primary
Secondary
Concomitant
Thrombocytopenia Death 4/2013 69 Female 139 lb 5/28/2013 Pharmacist Pt
Primary
Secondary
Concomitant
Herpes Zoster Hospitalization 3/19/2013 70 Male 183 lb 6/6/2013 Physician Us
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 4/23/2013 59 Male 264 lb 6/24/2013 Physician Us
Primary
Secondary
Concomitant
Epilepsy Other Serious 2/2013 27 Male 7/25/2013 Physician Gb
Primary
Concomitant
Nausea Other Serious 65 Male 7/25/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Neutrophil Count Decreased 8/6/2013 49 Male 206 lb 8/6/2013 Country Not Specified
Primary
Concomitant
Pulmonary Embolism Hospitalization 11/23/2010 67 Female 175 lb 8/16/2013 Physician Es
Primary
Concomitant
Neoplasm Progression Death 6/17/2011 73 Female 10/24/2013 Consumer Gb
Primary
Secondary
Concomitant
Grand Mal Convulsion Hospitalization 8/6/2013 49 Male 206 lb 8/27/2013 Country Not Specified
Primary
Concomitant
Gastrointestinal Haemorrhage Death 65 Male 9/13/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Neurological Decompensation Disability 4/13/2011 56 Male 172 lb 10/9/2013 Physician De
Primary
Secondary
Concomitant

Drug Data