Keppra combined with Temozolomide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Rash Pruritic Other Serious 12/30/2005 Male 234 lb 1/16/2006 United States
Primary
Concomitant
Pulmonary Embolism Required Intervention 2/1/2006 Female 186 lb 2/3/2006 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/18/2006 49 Female 5/5/2006 Physician United States
Primary
Secondary
Concomitant
Convulsion Hospitalization 4/15/2006 Male 245 lb 5/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/18/2006 49 Female 6/2/2006 Physician United States
Primary
Secondary
Concomitant
Hyponatraemia Required Intervention 7/18/2006 Male 188 lb 7/24/2006 United States
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Hospitalization 7/18/2006 85 Male 188 lb 7/27/2006 United States
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Hospitalization 7/18/2006 Male 188 lb 8/2/2006 United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/3/2006 Female 151 lb 10/6/2006 United States
Primary
Concomitant
Thrombocytopenia Hospitalization 10/19/2006 Female 151 lb 10/30/2006 United States
Primary
Concomitant
Lymphopenia Hospitalization 11/20/2006 Male 125 lb 11/20/2006 United States
Primary
Concomitant
Thrombocytopenia Hospitalization 10/19/2006 Female 151 lb 11/22/2006 United States
Primary
Concomitant
Status Epilepticus Hospitalization 11/17/2006 Male 147 lb 11/28/2006 United States
Primary
Concomitant
Ischaemic Stroke Hospitalization 11/23/2006 Male 215 lb 11/28/2006 United States
Primary
Concomitant
Lymphopenia 11/20/2006 Male 125 lb 12/18/2006 United States
Primary
Concomitant
Lymphopenia Hospitalization 11/20/2006 Male 125 lb 12/22/2006 United States
Primary
Concomitant
Lymphopenia 11/20/2006 Male 125 lb 12/26/2006 United States
Primary
Concomitant
Death 1/6/2007 Male 181 lb 1/16/2007 United States
Primary
Concomitant
Muscular Weakness Hospitalization 1/20/2007 Female 135 lb 1/24/2007 United States
Primary
Concomitant
Thrombocytopenia Hospitalization 10/19/2006 Female 151 lb 1/26/2007 United States
Primary
Concomitant
Pneumonia Hospitalization 1/28/2007 Female 130 lb 1/31/2007 United States
Primary
Concomitant
Refusal Of Treatment By Patient Hospitalization 1/28/2007 Female 130 lb 2/14/2007 United States
Primary
Concomitant
Thrombocytopenia 3/9/2007 Female 136 lb 3/14/2007 United States
Primary
Secondary
Concomitant
Thrombocytopenia 3/9/2007 Female 136 lb 4/2/2007 United States
Primary
Concomitant
Alanine Aminotransferase Increased 3/29/2007 Male 167 lb 4/6/2007 United States
Primary
Concomitant
Pancytopenia Hospitalization 3/18/2007 Male 135 lb 4/13/2007 United States
Primary
Secondary
Concomitant
Partial Seizures Hospitalization 9/27/2006 Female 130 lb 4/16/2007 United States
Primary
Concomitant
Ischaemic Stroke Hospitalization 11/23/2006 Male 215 lb 4/16/2007 United States
Primary
Concomitant
Death 2/12/2007 Female 118 lb 4/23/2007 United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/3/2007 Female 151 lb 5/8/2007 United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/8/2007 Female 151 lb 6/12/2007 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/8/2007 73 Female 152 lb 6/18/2007 Physician United States
Primary
Concomitant
Thrombosis Hospitalization 5/31/2006 Male 251 lb 6/28/2007 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 6/11/2007 Female 336 lb 6/22/2007 United States
Primary
Concomitant
Neutrophil Count Decreased 6/18/2007 Male 198 lb 7/3/2007 United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 3/11/2007 Male 188 lb 7/9/2007 United States
Primary
Concomitant
Urinary Tract Infection 7/2/2007 Female 143 lb 7/11/2007 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 3/29/2007 41 Male 167 lb 7/24/2007 Physician United States
Primary
Secondary
Concomitant
Septic Shock Death 5/28/2007 64 Male 150 lb 8/13/2007 Physician France
Primary
Concomitant
Ileus Hospitalization 8/3/2007 75 Male 162 lb 8/13/2007 Physician United States
Primary
Concomitant
Thrombocytopenia 3/9/2007 Female 136 lb 8/27/2007 United States
Primary
Concomitant
Haemorrhage Other Serious 1/18/2007 Male 9/11/2007 Physician United States
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 3/18/2007 68 Male 9/19/2007 United States
Primary
Secondary
Concomitant
Pulmonary Mass Hospitalization 9/11/2007 56 Female 176 lb 9/17/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Haemorrhage Other Serious 1/18/2007 Male 9/25/2007 Physician United States
Primary
Secondary
Concomitant
Diabetic Hyperosmolar Coma Hospitalization 9/5/2007 Male 167 lb 9/25/2007 United States
Primary
Concomitant
Disease Progression Hospitalization 7/6/2007 Male 154 lb 9/26/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Nephrolithiasis Other Serious 9/1/2006 52 Male 9/28/2007 Physician United States
Primary
Concomitant
Tachycardia Hospitalization 9/19/2007 56 Female 176 lb 10/2/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/19/2006 Female 151 lb 9/28/2007 United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 10/5/2007 Male 217 lb 10/8/2007 Consumer United States
Primary
Secondary
Concomitant
Lymphocyte Count Decreased 8/27/2007 Female 145 lb 10/10/2007 United States
Primary
Concomitant
Neoplasm Recurrence Hospitalization 10/18/2007 Female 194 lb 10/19/2007 United States
Primary
Concomitant
Malignant Neoplasm Progression Hospitalization 10/18/2007 59 Female 194 lb 10/24/2007 Physician United States
Primary
Secondary
Nervous System Disorder Hospitalization 8/27/2007 55 Male 185 lb 10/25/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Lymphopenia Hospitalization 10/18/2007 Female 194 lb 11/5/2007 United States
Primary
Concomitant
Intestinal Obstruction Hospitalization 10/26/2007 75 Male 153 lb 11/6/2007 Physician United States
Primary
Secondary
Oral Candidiasis Hospitalization 10/18/2007 59 Female 194 lb 11/7/2007 Physician United States
Primary
Secondary
Lower Gastrointestinal Haemorrhage Hospitalization 9/21/2007 Female 212 lb 11/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Systemic Candida Hospitalization 10/18/2007 59 Female 194 lb 11/9/2007 Physician United States
Primary
Secondary
Haemorrhoids Hospitalization 9/21/2007 Female 212 lb 11/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Infection Hospitalization 10/26/2007 75 Male 11/20/2007 Other Health Professional United States
Primary
Secondary
Proctalgia Hospitalization 10/19/2006 Female 151 lb 11/9/2007 United States
Primary
Concomitant
Oral Candidiasis Hospitalization 10/18/2007 Female 194 lb 11/19/2007 United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 10/26/2007 Male 153 lb 11/20/2007 United States
Primary
Concomitant
Oral Candidiasis Hospitalization 10/18/2007 59 Female 194 lb 11/20/2007 Physician United States
Primary
Secondary
Intestinal Obstruction Hospitalization 10/26/2007 75 Male 153 lb 11/21/2007 Physician United States
Primary
Secondary
Malignant Neoplasm Progression Death 10/18/2007 55 Male 185 lb 11/26/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Hospitalization 10/18/2007 Female 194 lb 11/26/2007 United States
Primary
Concomitant
Recurrent Cancer Death 10/8/2007 37 Male 168 lb 11/26/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Oral Candidiasis Hospitalization 10/18/2007 59 Female 194 lb 11/26/2007 Physician United States
Primary
Secondary
Intestinal Obstruction Hospitalization 10/23/2007 75 Male 11/21/2007 Consumer United States
Primary
Secondary
Systemic Candida Hospitalization 10/18/2007 59 Female 194 lb 11/27/2007 Physician United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 11/7/2007 51 Female 11/28/2007 Physician Spain
Primary
Concomitant
Oral Candidiasis Hospitalization 10/18/2007 59 Female 194 lb 11/28/2007 Physician United States
Primary
Secondary
Infection Hospitalization 10/26/2007 75 Male 12/5/2007 Other Health Professional United States
Primary
Secondary
Pulmonary Mass Death 9/18/2007 56 Female 176 lb 11/27/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 10/26/2007 Male 153 lb 11/28/2007 United States
Primary
Concomitant
Intestinal Obstruction Hospitalization 10/26/2007 75 Male 153 lb 12/3/2007 Physician United States
Primary
Secondary
Vomiting Hospitalization 11/25/2007 Male 196 lb 12/10/2007 United States
Primary
Concomitant
Urine Output Decreased Hospitalization 10/29/2007 Male 141 lb 12/4/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 10/29/2007 Male 141 lb 12/4/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Infection Hospitalization 10/26/2007 75 Male 153 lb 12/18/2007 Other Health Professional United States
Primary
Secondary
Confusional State Hospitalization 11/24/2007 44 Male 172 lb 12/22/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Oral Candidiasis Hospitalization 10/18/2007 59 Female 194 lb 12/14/2007 Physician United States
Primary
Secondary
Oliguria Hospitalization 10/29/2007 39 Male 141 lb 12/18/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 12/10/2007 75 Female 1/7/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/25/2007 Male 196 lb 1/3/2008 United States
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 12/10/2007 75 Female 1/7/2008 Physician Australia
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 6/11/2007 Female 336 lb 1/8/2008 United States
Primary
Concomitant
Somnolence Hospitalization 11/24/2007 44 Male 172 lb 1/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Haemorrhoids Hospitalization 9/21/2007 Female 212 lb 1/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/3/2007 50 Male 235 lb 1/17/2008 Physician United States
Primary
Concomitant
Neuropathy Peripheral Hospitalization 6/11/2007 71 Female 122 lb 2/8/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/13/2008 Female 162 lb 2/18/2008 United States
Primary
Concomitant
Thrombocytopenia Hospitalization 2/13/2008 Female 162 lb 2/19/2008 United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/25/2007 Male 196 lb 2/22/2008 United States
Primary
Concomitant
Pyrexia Hospitalization 12/10/2007 75 Female 3/3/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Renal Failure Hospitalization 2/11/2008 Female 203 lb 2/26/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Cerebral Haemorrhage Other Serious 1/18/2007 Male 4/4/2008 Physician United States
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 4/3/2008 Male 179 lb 4/15/2008 United States
Primary
Concomitant
Abdominal Pain Hospitalization 4/22/2008 Male 170 lb 4/29/2008 United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 10/5/2007 66 Male 218 lb 5/9/2008 Consumer United States
Primary
Secondary
Concomitant
Acute Myocardial Infarction Hospitalization 3/29/2008 65 Male 256 lb 6/9/2008 Physician United States
Primary
Secondary
Concomitant
Lymphopenia 5/27/2008 Female 164 lb 6/6/2008 United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/21/2008 Female 121 lb 6/10/2008 United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 6/19/2008 Male 196 lb 6/24/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 6/16/2008 Female 163 lb 6/25/2008 United States
Primary
Concomitant
Thrombocytopenia Hospitalization 7/18/2008 Female 145 lb 7/22/2008 United States
Primary
Concomitant
Lymphopenia Hospitalization 7/24/2008 Female 199 lb 8/1/2008 United States
Primary
Concomitant
Vision Blurred Hospitalization 1/1/2008 66 Male 245 lb 8/6/2008 United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 3/27/2008 Male 244 lb 7/28/2008 Physician United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Hospitalization 3/27/2008 Male 244 lb 8/5/2008 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 3/27/2008 66 Male 8/13/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pancreatitis Acute 10/5/2007 66 Male 218 lb 5/26/2008 Consumer United States
Primary
Secondary
Concomitant
Wound Infection Other Serious 7/9/2008 58 Male 196 lb 8/19/2008 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 8/5/2008 Male 289 lb 8/20/2008 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 7/28/2008 74 Female 140 lb 8/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 3/27/2008 Male 244 lb 9/2/2008 United States
Primary
Secondary
Concomitant
Wound Infection Death 7/18/2008 Male 196 lb 9/11/2008 Consumer United States
Primary
Secondary
Concomitant
Tremor Hospitalization 11/25/2007 Female 140 lb 9/5/2008 Canada
Primary
Concomitant
Vision Blurred Hospitalization 1/1/2008 66 Male 245 lb 9/15/2008 United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 8/16/2008 60 Female 148 lb 9/30/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 10/13/2008 38 Male 10/21/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Tachycardia Hospitalization 10/13/2008 38 Male 10/22/2008 Physician Australia
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 10/13/2008 38 Male 11/6/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Tachycardia Hospitalization 10/13/2008 38 Male 11/5/2008 Physician Australia
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 8/29/2007 Male 250 lb 11/5/2008 United States
Primary
Concomitant
Confusional State Hospitalization 10/10/2007 Male 261 lb 11/5/2008 United States
Primary
Concomitant
Muscular Weakness Other Serious 10/10/2007 66 Male 261 lb 11/24/2008 Physician United States
Primary
Secondary
Malignant Neoplasm Progression Death 12/1/2008 Female 143 lb 12/1/2008 Consumer United States
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 10/10/2007 Male 261 lb 12/4/2008 United States
Primary
Concomitant
Hepatic Steatosis Hospitalization 9/22/2008 50 Male 141 lb 11/26/2008 Other Health Professional Austria
Primary
Secondary
Urinary Tract Infection Hospitalization 8/26/2008 75 Male 198 lb 12/4/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Infarction Hospitalization 8/8/2008 75 Female 152 lb 12/4/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Wheezing Hospitalization 8/30/2008 75 Male 196 lb 12/4/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Hospitalization 12/7/2008 Male 141 lb 12/9/2008 Consumer United States
Primary
Secondary
Concomitant
Muscular Weakness Other Serious 10/10/2007 66 Male 261 lb 12/11/2008 Physician United States
Primary
Secondary
Concomitant
Pulmonary Infarction Hospitalization 8/8/2008 75 Female 150 lb 12/11/2008 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 8/26/2008 75 Male 198 lb 12/12/2008 Physician United States
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 10/13/2008 38 Male 12/18/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 10/10/2007 66 Male 261 lb 12/15/2008 United States
Primary
Secondary
Pancytopenia Hospitalization 2/8/2009 Female 139 lb 2/18/2009 United States
Primary
Concomitant
Pancytopenia 7/1/2008 Female 139 lb 2/18/2009 United States
Primary
Concomitant
Cardiac Arrest Death 2/16/2009 62 Male 293 lb 3/3/2009 Physician United States
Primary
Secondary
Concomitant
Cardiac Arrest Death 2/16/2009 Male 293 lb 3/7/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Sudden Death Death 9/9/2008 55 Male 209 lb 3/5/2009 Physician United States
Primary
Secondary
Concomitant
Cardiac Arrest Hospitalization 9/9/2008 Female 209 lb 3/11/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Dehiscence Hospitalization 9/6/2008 64 NotSpecified 183 lb 3/10/2009 Physician United States
Primary
Secondary
Concomitant
Osteomyelitis Hospitalization 1/9/2009 36 Female 3/23/2009 Physician United States
Primary
Secondary
Concomitant

Drug Data