Avastin combined with Temozolomide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Decreased Hospitalization 11/5/2005 51 Male 183 lb 12/29/2005 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/11/2008 68 Male 5/20/2008 Physician Switzerland
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 10/10/2008 Male 10/24/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 10/10/2008 Male 11/5/2008 Other Health Professional United Kingdom
Primary
Concomitant
Disease Progression Other Serious 59 Male 4/2/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Epistaxis Other Serious 43 Male 4/2/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Epistaxis Other Serious 60 Male 4/3/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Hepatic Function Abnormal Hospitalization 15 Male 4/3/2009 Consumer United Kingdom
Primary
Secondary
Neurotoxicity Hospitalization 5/14/2009 80 Male 6/8/2009 Physician Switzerland
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 10/16/2009 57 Female 164 lb 11/3/2009 Physician United States
Primary
Secondary
Thrombocytopenia Hospitalization 8/27/2009 Female 11/19/2009 Physician United States
Primary
Secondary
Concomitant
Status Epilepticus Death Female 11/20/2009 Physician United Kingdom
Primary
Concomitant
Status Epilepticus Other Serious Female 11/20/2009 Physician United Kingdom
Primary
Concomitant
Hypertension Other Serious Male 11/20/2009 Physician United Kingdom
Primary
Concomitant
Neoplasm Malignant Other Serious 10/2/2009 Female 11/20/2009 Physician United Kingdom
Primary
Concomitant
Neoplasm Malignant Death Male 11/23/2009 Consumer Germany
Primary
Concomitant
Neoplasm Malignant Death Male 11/24/2009 Physician United Kingdom
Primary
Concomitant
Thrombocytopenia Hospitalization 8/27/2009 Female 12/4/2009 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Abnormal Hospitalization 10/16/2009 57 Female 164 lb 12/18/2009 Physician United States
Primary
Secondary
Vena Cava Filter Insertion Hospitalization 10/30/2009 Male 152 lb 12/29/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 1/6/2010 Male 221 lb 1/13/2010 Physician United States
Primary
Secondary
Concomitant
Vena Cava Filter Insertion Hospitalization 10/30/2009 Male 152 lb 1/28/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vena Cava Filter Insertion Hospitalization 1/6/2010 Male 221 lb 1/28/2010 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 8/6/2009 Female 1/29/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/30/2009 Male 210 lb 2/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 11/21/2009 Male 206 lb 2/4/2010 Physician United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 2/9/2010 Female 204 lb 2/17/2010 Physician United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 2/9/2010 Female 204 lb 3/1/2010 Physician United States
Primary
Secondary
Concomitant
Vena Cava Filter Insertion Hospitalization 1/6/2010 Male 221 lb 3/8/2010 Physician United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Death 3/1/2010 Female 128 lb 3/8/2010 Physician United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 2/9/2010 Female 204 lb 3/12/2010 Physician United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 2/9/2010 Female 204 lb 3/26/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/29/2010 53 Female 171 lb 5/4/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 9/22/2009 48 Male 170 lb 5/11/2010 Physician United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 3/9/2010 48 Male 170 lb 5/13/2010 Physician United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 2/9/2010 52 Female 204 lb 5/24/2010 Physician United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 3/1/2010 62 Female 128 lb 5/28/2010 Physician United States
Primary
Secondary
Concomitant
Disease Progression Death 58 Female 6/15/2010 Other Health Professional Spain
Primary
Secondary
Weight Decreased Hospitalization 3/30/2010 32 Female 136 lb 9/14/2010 Physician United States
Primary
Secondary
Concomitant
Interacting
Large Intestine Perforation Hospitalization 11/12/2009 65 Male 176 lb 9/30/2010 Other Health Professional France
Primary
Secondary
Concomitant
Large Intestine Perforation Hospitalization 11/12/2009 65 Male 176 lb 10/8/2010 Other Health Professional France
Primary
Secondary
Concomitant
Epilepsy Hospitalization 12/28/2010 50 Male 1/6/2011 Other Health Professional Italy
Primary
Concomitant
Epilepsy Hospitalization 12/28/2010 50 Male 1/18/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Lymphocyte Count Decreased Hospitalization 12/23/2010 70 Female 131 lb 1/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 30 Female 2/1/2011 Consumer China
Primary
Concomitant
Cholecystitis Hospitalization 12/31/2010 52 Male 183 lb 2/2/2011 Physician France
Primary
Secondary
Concomitant
Chemical Peritonitis Hospitalization 12/31/2010 52 Male 183 lb 2/11/2011 Physician France
Primary
Secondary
Concomitant
Cholecystitis Hospitalization 12/31/2010 52 Male 183 lb 3/21/2011 Physician France
Primary
Secondary
Concomitant
Pulmonary Embolism Death 4/29/2011 73 Female 196 lb 5/6/2011 Physician France
Primary
Secondary
Diplopia Hospitalization 4/19/2011 Male 143 lb 5/9/2011 Physician United States
Primary
Secondary
Convulsion Hospitalization 4/17/2011 66 Male 144 lb 5/10/2011 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 5/5/2011 57 Female 150 lb 5/11/2011 Physician United States
Primary
Secondary
Concomitant
Convulsion Death Male 177 lb 7/29/2011 Physician Australia
Primary
Concomitant
Stitch Abscess Death 8/17/2011 Physician United States
Primary
Secondary
Concomitant
Tumour Haemorrhage Other Serious 7/18/2011 52 Female 123 lb 9/1/2011 Physician France
Primary
Secondary
Concomitant
Proteinuria Other Serious 1/1/2010 65 Male 9/23/2011 Physician Israel
Primary
Concomitant
Confusional State Hospitalization 12/16/2010 53 Male 183 lb 10/5/2011 Physician Italy
Primary
Secondary
Concomitant
Brain Oedema Hospitalization 12/24/2010 54 Female 144 lb 10/6/2011 Canada
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 9/1/2011 50 Male 10/11/2011 Physician Taiwan, Province Of China
Primary
Concomitant
Convulsion Hospitalization 9/29/2011 63 Female 10/18/2011 Physician United States
Primary
Secondary
Dysphagia Life Threatening 10/10/2011 52 Female 159 lb 10/19/2011 United States
Primary
Secondary
Haemorrhage Intracranial Hospitalization 9/30/2011 63 Female 10/20/2011 United States
Primary
Secondary
Convulsion Hospitalization 10/19/2011 51 Male 10/25/2011 Spain
Primary
Secondary
Cerebral Infarction Hospitalization 10/18/2011 59 Male 165 lb 10/26/2011 United States
Primary
Secondary
Concomitant
Ataxia Hospitalization 7/19/2011 71 10/31/2011 United States
Primary
Secondary
Pyrexia Hospitalization 4/9/2011 74 Male 194 lb 10/31/2011 Physician Germany
Primary
Secondary
Concomitant
Convulsion Hospitalization 3/15/2011 52 Female 135 lb 11/1/2011 Physician United States
Primary
Secondary
Deep Vein Thrombosis Hospitalization 4/23/2011 58 Male 190 lb 11/2/2011 Physician Sweden
Primary
Secondary
Concomitant
Confusional State Hospitalization 10/4/2011 74 Female 139 lb 11/2/2011 United States
Primary
Secondary
Concomitant
Paraesthesia Hospitalization 8/9/2011 56 Male 154 lb 11/2/2011 Physician United States
Primary
Secondary
Convulsion Hospitalization 10/18/2011 51 Male 236 lb 11/7/2011 Physician Spain
Primary
Secondary
Nausea Other Serious 11/17/2011 Physician United States
Primary
Secondary
Fungal Infection Other Serious 11/18/2011 United States
Primary
Secondary
Death Other Serious 11/23/2010 37 Male 232 lb 11/23/2011 Canada
Primary
Concomitant
Alanine Aminotransferase Increased Other Serious 8/1/2011 5 Female 11/24/2011 Physician United States
Primary
Secondary
Subileus Hospitalization 9/11/2011 82 Female 154 lb 11/21/2011 Physician France
Primary
Secondary
Concomitant
Chemical Peritonitis Hospitalization 12/31/2010 52 Male 183 lb 12/1/2011 Physician France
Primary
Secondary
Concomitant
Endocarditis Bacterial Hospitalization 5/3/2011 45 Male 12/2/2011 Physician France
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 9/1/2011 50 Male 12/5/2011 Physician Taiwan, Province Of China
Primary
Concomitant
Haematuria Hospitalization 10/19/2011 59 Male 165 lb 12/5/2011 United States
Primary
Secondary
Concomitant
Ill-defined Disorder Hospitalization 3/15/2011 75 Female 130 lb 12/9/2011 France
Primary
Secondary
Concomitant
Partial Seizures Hospitalization 12/30/2010 63 Female 157 lb 12/9/2011 Physician France
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 3/28/2011 66 Male 381 lb 12/15/2011 Japan
Primary
Secondary
Concomitant
Convulsion Hospitalization 10/10/2011 52 Female 159 lb 12/16/2011 United States
Primary
Secondary
Impaired Healing Hospitalization 1/2/2012 74 Female 132 lb 1/4/2012 Germany
Primary
Secondary
Concomitant
Neoplasm Malignant Other Serious Female 141 lb 1/11/2012 Canada
Primary
Concomitant
Impaired Healing Hospitalization 1/2/2012 74 Female 132 lb 1/12/2012 Germany
Primary
Secondary
Concomitant
Anal Fissure Hospitalization 1/1/2012 72 Male 121 lb 1/18/2012 France
Primary
Secondary
Cystitis Hospitalization 10/29/2011 53 Female 162 lb 1/25/2012 Physician United States
Primary
Secondary
Gamma-glutamyltransferase Increased Hospitalization 1/11/2010 51 Male 168 lb 1/25/2012 Belgium
Primary
Secondary
Concomitant
Disease Progression Other Serious 1/1/2011 70 Female 1/27/2012 Canada
Primary
Concomitant
Anal Fissure Hospitalization 1/1/2012 72 Male 121 lb 2/2/2012 France
Primary
Secondary
Pyelonephritis Hospitalization 1/28/2012 Female 2/2/2012 Physician France
Primary
Secondary
Concomitant
Haematuria Other Serious 4/20/2011 61 Male 75 lb 2/2/2012 Other Health Professional Spain
Primary
Secondary
Neutropenia Other Serious 7/18/2011 52 Female 123 lb 2/9/2012 Physician France
Primary
Secondary
Concomitant
Pneumonitis Other Serious 11/17/2009 54 Female 118 lb 2/14/2012 United States
Primary
Concomitant
Pneumocystis Jiroveci Infection Other Serious 2/14/2012 United States
Primary
Secondary
Vasculitis Other Serious 60 Female 2/15/2012 Physician Japan
Primary
Concomitant
Malaise Other Serious 61 Female 2/15/2012 Physician Japan
Primary
Secondary
Concomitant
Haemorrhage Other Serious 2/17/2012 United States
Primary
Secondary
Haemorrhage Other Serious 2/17/2012 United States
Primary
Secondary
Cerebrovascular Accident Death 5/19/2011 60 Male 189 lb 2/20/2012 Physician Netherlands
Primary
Secondary
Concomitant
Death Death 2/23/2012 Denmark
Primary
Secondary
Death Death 2/14/2012 70 Female 148 lb 2/24/2012 France
Primary
Secondary
Concomitant
Colitis Other Serious 3/2/2012 United States
Primary
Secondary
Asthenia Death 2/14/2012 70 Female 148 lb 3/7/2012 Physician France
Primary
Secondary
Concomitant
Pneumonitis Death 11/17/2009 54 Female 118 lb 3/7/2012 United States
Primary
Concomitant
Death Death 38 Female 3/15/2012 United States
Primary
Secondary
Gait Disturbance Hospitalization 3/15/2011 75 Female 130 lb 3/28/2012 France
Primary
Secondary
Concomitant
Death Death Female 212 lb 3/29/2012 United States
Primary
Secondary
Gliomatosis Cerebri Hospitalization 12/13/2011 38 Male 172 lb 3/30/2012 Physician Germany
Primary
Secondary
Concomitant
Gliomatosis Cerebri Hospitalization 12/13/2011 38 Male 172 lb 4/3/2012 Physician Germany
Primary
Secondary
Concomitant
Gliomatosis Cerebri Death 12/13/2011 38 Male 172 lb 4/5/2012 Physician Germany
Primary
Secondary
Concomitant
Leukoencephalopathy Hospitalization 3/10/2011 59 Male 185 lb 4/19/2012 France
Primary
Secondary
Concomitant
Renal Failure Other Serious 4/27/2012 United States
Primary
Secondary
Leukoencephalopathy Hospitalization 3/10/2011 59 Male 185 lb 5/2/2012 France
Primary
Secondary
Concomitant
Leukoencephalopathy Hospitalization 3/10/2011 59 Male 185 lb 5/3/2012 Physician France
Primary
Secondary
Concomitant
Epilepsy Hospitalization 3/26/2012 53 Male 171 lb 5/4/2012 Physician Germany
Primary
Secondary
Concomitant
Fatigue Hospitalization 4/23/2012 78 Male 5/8/2012 Physician United States
Primary
Secondary
Leukoencephalopathy Hospitalization 3/10/2011 59 Male 185 lb 5/9/2012 France
Primary
Secondary
Concomitant
Status Epilepticus Hospitalization 5/1/2012 62 Female 135 lb 5/10/2012 United States
Primary
Secondary
Concomitant
Leukoencephalopathy Life Threatening 3/10/2011 59 Male 185 lb 5/11/2012 France
Primary
Secondary
Concomitant
Optic Nerve Disorder Other Serious 10/4/2011 70 Male 164 lb 5/21/2012 United States
Primary
Secondary
Disease Progression Other Serious 3/18/2012 52 Female 175 lb 5/23/2012 Physician Canada
Primary
Secondary
Concomitant
Blindness Other Serious 54 Female 5/24/2012 Turkey
Primary
Concomitant
Death Death Female 212 lb 5/25/2012 United States
Primary
Secondary
Brain Oedema Hospitalization 1/28/2011 57 Male 221 lb 5/28/2012 Canada
Primary
Secondary
Concomitant
Diarrhoea Other Serious 5/29/2012 Switzerland
Primary
Secondary
Peritonitis Hospitalization 5/6/2012 60 Female 132 lb 6/1/2012 Physician Germany
Primary
Secondary
Concomitant
Neutropenia Death 6/6/2012 Other Health Professional United States
Primary
Secondary
Intestinal Perforation Other Serious 6/6/2012 United States
Primary
Secondary
Peritonitis Hospitalization 5/6/2012 60 Female 132 lb 6/6/2012 Physician Germany
Primary
Secondary
Concomitant
Rash Maculo-papular Hospitalization 4/20/2012 8 Male 49 lb 6/15/2012 United States
Primary
Secondary
Dyspnoea Other Serious 6/19/2012 Physician United States
Primary
Secondary
Hyperkalaemia Other Serious 11/7/2011 7 Male 6/26/2012 Physician United States
Primary
Secondary
Disease Progression Death 7/19/2011 71 7/2/2012 Physician United States
Primary
Secondary
Brain Neoplasm Malignant Death 11/3/2011 78 Male 119 lb 7/5/2012 Physician France
Primary
Secondary
Concomitant
Asthenia Other Serious Female 7/18/2012 Consumer United States
Primary
Secondary
Convulsion Hospitalization 6/15/2012 55 Female 157 lb 7/18/2012 Other Health Professional United States
Primary
Concomitant
Aphasia Hospitalization 6/15/2012 55 Female 157 lb 7/27/2012 Other Health Professional United States
Primary
Concomitant
Somnolence Hospitalization 8/1/2012 12 Male 110 lb 8/20/2012 Physician Sweden
Primary
Secondary
Concomitant
Deep Vein Thrombosis Other Serious 8/22/2012 Physician United States
Primary
Secondary
Osteoporotic Fracture Disability 7/19/2011 50 Female 174 lb 8/24/2012 Physician France
Primary
Secondary
Concomitant
Spinal Osteoarthritis Hospitalization 10/30/2009 75 Male 152 lb 12/17/2012 Physician Us
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 3/1/2010 62 Female 129 lb 12/5/2012 Physician Us
Primary
Secondary
Concomitant
Melaena Other Serious 3/9/2010 49 Male 170 lb 12/18/2012 Consumer Country Not Specified
Primary
Secondary
Concomitant
Rash Death Male 9/17/2012 Physician Us
Primary
Secondary
Concomitant
Convulsion Hospitalization 12/1/2011 63 Male 149 lb 9/20/2012 Physician De
Primary
Secondary
Concomitant
Vision Blurred Death Male 9/24/2012 Physician Us
Primary
Secondary
Concomitant
Vomiting Other Serious 9/24/2012 Other Health Professional Country Not Specified
Primary
Secondary

Drug Data