Bevacizumab combined with Temozolomide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Haemorrhage Other Serious 1/18/2007 Male 9/11/2007 Physician United States
Primary
Secondary
Concomitant
Haemorrhage Other Serious 1/18/2007 Male 9/25/2007 Physician United States
Primary
Secondary
Concomitant
Idiopathic Thrombocytopenic Purpura Hospitalization 9/11/2007 67 Male 184 lb 11/2/2007 Physician United States
Primary
Secondary
Pancreatitis Acute Hospitalization Male 243 lb 11/15/2007 Physician United States
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 10/13/2007 44 Male 11/12/2007 Physician United States
Primary
Secondary
Concomitant
Haemorrhoids Hospitalization 9/21/2007 Female 212 lb 11/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 10/13/2007 44 Male 243 lb 11/15/2007 Physician United States
Primary
Secondary
Concomitant
Herpes Zoster Other Serious 11/26/2007 62 Male 156 lb 12/6/2007 Physician United States
Primary
Secondary
Herpes Zoster Other Serious 11/26/2007 62 Male 156 lb 12/12/2007 Physician United States
Primary
Secondary
Concomitant
Confusional State Hospitalization 11/24/2007 44 Male 172 lb 12/22/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 12/9/2007 60 Female 180 lb 12/22/2007 Physician United States
Primary
Concomitant
Oliguria Hospitalization 10/29/2007 39 Male 141 lb 12/18/2007 Physician United States
Primary
Secondary
Concomitant
Encephalopathy Hospitalization 12/12/2007 Female 124 lb 12/28/2007 Physician United States
Primary
Secondary
Encephalopathy Hospitalization 11/6/2007 60 Female 180 lb 1/2/2008 Physician United States
Primary
Concomitant
Somnolence Hospitalization 11/24/2007 44 Male 172 lb 1/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Haemorrhoids Hospitalization 9/21/2007 Female 212 lb 1/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 12/9/2007 60 Female 180 lb 1/18/2008 Physician United States
Primary
Concomitant
Mental Status Changes Hospitalization 12/9/2007 60 Female 180 lb 2/15/2008 Physician United States
Primary
Concomitant
Multi-organ Failure Hospitalization 1/28/2008 80 Female 2/19/2008 Physician United States
Primary
Secondary
Renal Failure Hospitalization 12/27/2006 53 Female 3/12/2008 Physician United States
Primary
Secondary
Concomitant
Cerebral Haemorrhage Other Serious 1/18/2007 Male 4/4/2008 Physician United States
Primary
Secondary
Concomitant
Suicide Attempt Hospitalization 1/28/2008 70 Female 157 lb 5/2/2008 Physician United States
Primary
Secondary
Activated Partial Thromboplastin Time Prolonged Hospitalization 3/29/2008 Male 5/15/2008 Other Health Professional United States
Primary
Secondary
Acute Myocardial Infarction Hospitalization 3/29/2008 65 Male 256 lb 6/9/2008 Physician United States
Primary
Secondary
Concomitant
Motor Dysfunction Hospitalization 6/15/2008 Male 183 lb 6/20/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Bacterial Hospitalization 6/9/2008 65 Male 243 lb 7/1/2008 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 1/1/2008 66 Male 245 lb 8/6/2008 United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 3/27/2008 Male 244 lb 7/28/2008 Physician United States
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 11/6/2007 60 Female 180 lb 8/8/2008 Physician United States
Primary
Secondary
Vision Blurred Hospitalization 3/27/2008 66 Male 8/13/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Other Serious 7/9/2008 58 Male 196 lb 8/19/2008 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 8/5/2008 Male 289 lb 8/20/2008 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 7/28/2008 74 Female 140 lb 8/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Death 7/18/2008 Male 196 lb 9/11/2008 Consumer United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 1/1/2008 66 Male 245 lb 9/15/2008 United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 53 Female 9/29/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Convulsion Other Serious 67 Male 9/29/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Lethargy Other Serious 66 Male 9/30/2008 Consumer United Kingdom
Primary
Secondary
Wound Decomposition Other Serious 46 Female 9/30/2008 Consumer United Kingdom
Primary
Secondary
Pulmonary Embolism Other Serious 60 Female 9/30/2008 Physician United Kingdom
Primary
Secondary
Thrombocytopenia Hospitalization 8/16/2008 60 Female 148 lb 9/30/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Alveolitis Hospitalization 9/1/2008 Female 10/21/2008 Physician United Kingdom
Primary
Secondary
Death Death 3/29/2008 71 Female 154 lb 10/29/2008 Physician United States
Primary
Secondary
Concomitant
Death Death 5/9/2008 45 Male 175 lb 11/5/2008 Physician United States
Primary
Secondary
Concomitant
Alveolitis Other Serious 9/22/2008 Female 11/6/2008 Physician United Kingdom
Primary
Secondary
Acute Abdomen Death 9/5/2008 Male 11/11/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Death 12/1/2008 Female 143 lb 12/1/2008 Consumer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 8/26/2008 75 Male 198 lb 12/4/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Infarction Hospitalization 8/8/2008 75 Female 152 lb 12/4/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Wheezing Hospitalization 8/30/2008 75 Male 196 lb 12/4/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Hospitalization 12/7/2008 Male 141 lb 12/9/2008 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/24/2008 45 Female 112 lb 12/9/2008 Physician United States
Primary
Secondary
Concomitant
Convulsion Hospitalization 12/6/2007 47 Male 189 lb 12/12/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/30/2008 75 Male 196 lb 12/11/2008 Physician United States
Primary
Secondary
Concomitant
Pulmonary Infarction Hospitalization 8/8/2008 75 Female 150 lb 12/11/2008 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 8/26/2008 75 Male 198 lb 12/12/2008 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 2/19/2009 Female 119 lb 2/26/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 2/13/2009 Female 3/4/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Grand Mal Convulsion Hospitalization 8/7/2008 Male 176 lb 2/26/2009 Consumer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 12/17/2008 Female 170 lb 3/4/2009 United States
Primary
Secondary
Concomitant
Cardiac Arrest Death 2/16/2009 62 Male 293 lb 3/3/2009 Physician United States
Primary
Secondary
Concomitant
Cardiac Arrest Death 2/16/2009 Male 293 lb 3/7/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 1/7/2009 Female 170 lb 3/5/2009 Consumer United States
Primary
Secondary
Concomitant
Sudden Death Death 9/9/2008 55 Male 209 lb 3/5/2009 Physician United States
Primary
Secondary
Concomitant
Cardiac Arrest Hospitalization 9/9/2008 Female 209 lb 3/11/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Dehiscence Hospitalization 9/6/2008 64 NotSpecified 183 lb 3/10/2009 Physician United States
Primary
Secondary
Concomitant
Intestinal Perforation Hospitalization 12/19/2008 59 Female 214 lb 3/11/2009 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/3/2009 58 Male 247 lb 3/18/2009 Physician United States
Primary
Secondary
Concomitant
Osteomyelitis Hospitalization 1/9/2009 36 Female 3/23/2009 Physician United States
Primary
Secondary
Concomitant
Rash Hospitalization 4/17/2009 72 Female 143 lb 4/24/2009 Physician United States
Primary
Secondary
Intracranial Hypotension Hospitalization 4/24/2009 Male 195 lb 5/6/2009 Consumer United States
Primary
Secondary
Pyrexia Hospitalization 4/9/2009 Male 5/6/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Cardiac Arrest Death 2/16/2009 Male 293 lb 5/7/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Duodenal Ulcer Haemorrhage Life Threatening 4/24/2009 Male 5/7/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Duodenal Ulcer Haemorrhage Life Threatening 4/24/2009 Male 5/14/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 2/13/2009 Female 5/12/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Intracranial Hypotension Hospitalization 4/24/2009 Male 195 lb 5/15/2009 Consumer United States
Primary
Secondary
Pancreatitis Hospitalization 4/24/2009 Male 226 lb 5/22/2009 Physician United States
Primary
Concomitant
Lobar Pneumonia Hospitalization 5/2/2009 68 Female 152 lb 5/19/2009 Physician United States
Primary
Secondary
Concomitant
Intracranial Hypotension Hospitalization 4/24/2009 Male 195 lb 5/26/2009 Consumer United States
Primary
Secondary
White Blood Cell Disorder Hospitalization 5/12/2009 Female 160 lb 5/28/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Dementia Hospitalization 5/14/2009 Male 5/29/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Optic Neuropathy Other Serious 63 Female 6/10/2009 Physician United States
Primary
Concomitant
Optic Neuropathy Other Serious 68 Male 6/10/2009 Physician United States
Primary
Concomitant
Optic Neuropathy Other Serious 59 Female 6/10/2009 Physician United States
Primary
Concomitant
Optic Neuropathy Other Serious 67 Female 6/10/2009 Physician United States
Primary
Concomitant
Optic Neuropathy Other Serious 48 Female 6/10/2009 Physician United States
Primary
Concomitant
Optic Neuropathy Other Serious 37 Female 6/10/2009 Physician United States
Primary
Concomitant
Duodenal Ulcer Haemorrhage Life Threatening 4/24/2009 Male 6/11/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Dementia Hospitalization 5/14/2009 Male 6/17/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/9/2009 Male 6/19/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Dementia Hospitalization 5/14/2009 Male 6/26/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Confusional State Hospitalization 6/16/2009 Male 7/1/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/6/2009 67 Female 212 lb 6/30/2009 Physician United States
Primary
Secondary
Concomitant
Intracranial Hypotension Hospitalization 4/24/2009 Male 195 lb 7/8/2009 Consumer United States
Primary
Secondary
Respiratory Distress Hospitalization 4/25/2009 54 Male 146 lb 7/6/2009 Physician United States
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 4/25/2009 Male 7/9/2009 Consumer United States
Primary
Secondary
Concomitant
Loss Of Consciousness Life Threatening 6/12/2009 Male 219 lb 7/15/2009 Physician United States
Primary
Concomitant
Hyperhidrosis Hospitalization 6/12/2009 Male 219 lb 7/16/2009 Other Health Professional United States
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 4/25/2009 Male 7/17/2009 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/28/2009 28 Female 218 lb 8/3/2009 Physician United States
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 4/25/2009 Male 8/6/2009 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Disorder Hospitalization 5/12/2009 Female 160 lb 8/7/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 4/25/2009 54 Male 146 lb 8/4/2009 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/6/2009 67 Female 212 lb 8/5/2009 Physician United States
Primary
Secondary
Concomitant
Neutrophil Count Decreased Hospitalization 5/2/2009 68 Female 152 lb 8/5/2009 Physician United States
Primary
Secondary
Concomitant
Post Procedural Complication Hospitalization 1/9/2009 36 Female 8/5/2009 Physician United States
Primary
Secondary
Concomitant
Loss Of Consciousness Life Threatening 6/12/2009 Male 219 lb 8/25/2009 Physician United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 8/16/2009 64 Male 202 lb 9/2/2009 Physician United States
Primary
Secondary
Glioblastoma Multiforme Death 3/29/2008 71 Female 154 lb 9/15/2009 Physician United States
Primary
Secondary
Concomitant
Neutropenia Other Serious 55 Male 9/18/2009 Physician United Kingdom
Primary
Secondary
Pyrexia Hospitalization 9/24/2009 Female 175 lb 10/14/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/15/2009 Female 175 lb 10/15/2009 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/15/2009 Female 175 lb 10/16/2009 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/15/2009 Female 175 lb 10/21/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/24/2009 Female 175 lb 10/21/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 8/27/2009 Female 11/13/2009 Physician United States
Primary
Secondary
Concomitant
Leukopenia Death Female 11/20/2009 Physician United Kingdom
Primary
Concomitant
Malignant Neoplasm Progression Other Serious Male 11/20/2009 Physician United Kingdom
Primary
Concomitant
Status Epilepticus Other Serious Male 11/20/2009 Physician United Kingdom
Primary
Concomitant
Pulmonary Embolism Death Male 11/20/2009 Physician United Kingdom
Primary
Concomitant
Encephalitic Infection Hospitalization 11/5/2009 Female 134 lb 11/23/2009 Physician United States
Primary
Secondary
Leukopenia Death Female 11/23/2009 Physician United Kingdom
Primary
Concomitant
Pulmonary Embolism Death Male 11/23/2009 Physician United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious 8/17/2009 Male 11/23/2009 Physician Germany
Primary
Concomitant
Thrombocytopenia Hospitalization 8/27/2009 Female 11/23/2009 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 8/27/2009 Female 12/1/2009 Physician United States
Primary
Secondary
Concomitant
Pneumothorax Hospitalization 12/2/2009 Male 12/17/2009 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 11/17/2009 Female 12/24/2009 Physician Denmark
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 12/24/2009 55 Male 192 lb 12/28/2009 Physician United States
Primary
Secondary
Oesophageal Infection Hospitalization 12/10/2009 Female 163 lb 1/6/2010 Physician United States
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 1/18/2010 53 Female 2/2/2010 Physician Switzerland
Primary
Secondary
Pneumonitis Hospitalization 11/23/2009 Male 206 lb 2/4/2010 Physician United States
Primary
Secondary
Concomitant
Death Death 126 lb 2/8/2010 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/15/2009 Female 175 lb 2/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 1/18/2010 53 Female 2/10/2010 Physician Switzerland
Primary
Secondary
Pneumonitis Hospitalization 11/23/2009 Male 206 lb 2/16/2010 Physician United States
Primary
Secondary
Concomitant
Disease Progression Death 126 lb 3/2/2010 Physician United States
Primary
Secondary
Concomitant
Oesophageal Infection Hospitalization 12/10/2009 Female 163 lb 3/2/2010 Physician United States
Primary
Secondary
Concomitant
Oesophageal Infection Hospitalization 12/10/2009 Female 163 lb 3/3/2010 Physician United States
Primary
Secondary
Concomitant
Pneumothorax Hospitalization 12/1/2009 Male 207 lb 3/5/2010 Physician United States
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 1/18/2010 53 Female 3/15/2010 Physician Switzerland
Primary
Secondary
Myelodysplastic Syndrome Other Serious 16 Male 3/10/2010 Physician United States
Primary
Secondary
Pyrexia Hospitalization 3/4/2010 Male 188 lb 3/19/2010 Physician United States
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 12/10/2009 52 Female 3/12/2010 Physician United States
Primary
Secondary
Concomitant
Sputum Discoloured Hospitalization 12/1/2009 54 Male 3/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Haemorrhagic Stroke Death 3/1/2010 Female 128 lb 3/29/2010 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/4/2010 Male 188 lb 3/30/2010 Physician United States
Primary
Secondary
Concomitant
Oedema Other Serious 3/8/2010 Female 204 lb 3/30/2010 Physician United States
Primary
Secondary
Haemorrhagic Stroke Death 3/1/2010 62 Female 128 lb 4/6/2010 Physician United States
Primary
Secondary
Concomitant

Drug Data