Saquinavir



Indications and Reactions:

Role Indications Reactions
Primary
Hiv Infection 47.4%
Drug Use For Unknown Indication 29.1%
Product Used For Unknown Indication 9.6%
Antiretroviral Therapy 3.5%
Burkitt's Lymphoma 2.7%
Prophylaxis Against Hiv Infection 2.5%
Acquired Immunodeficiency Syndrome 0.8%
Ill-defined Disorder 0.6%
Mycobacterium Avium Complex Infection 0.5%
Systemic Antiviral Treatment 0.5%
Diarrhoea 0.4%
Insomnia 0.4%
Opportunistic Infection Prophylaxis 0.4%
Oral Candidiasis 0.4%
Anaemia Prophylaxis 0.3%
Non-small Cell Lung Cancer Stage Iv 0.3%
Prophylaxis 0.3%
Retroviral Infection 0.3%
Candidiasis 0.1%
Chemotherapy 0.1%
Deep Vein Thrombosis 25.0%
Joint Dislocation 7.7%
Hydrocele 5.8%
Osteonecrosis 5.8%
Sepsis 5.8%
Treatment Failure 5.8%
Death 4.8%
Pruritus 4.8%
Stillbirth 4.8%
Abortion Spontaneous 3.8%
Trisomy 21 3.8%
Foetal Exposure During Pregnancy 2.9%
Hepatotoxicity 2.9%
Progressive External Ophthalmoplegia 2.9%
Tracheo-oesophageal Fistula 2.9%
Virologic Failure 2.9%
Cardiotoxicity 1.9%
Cerebral Toxoplasmosis 1.9%
Dystrophia Myotonica 1.9%
Electrocardiogram Qt Prolonged 1.9%
Secondary
Hiv Infection 62.5%
Drug Use For Unknown Indication 6.4%
Burkitt's Lymphoma 5.1%
Drug Exposure During Pregnancy 4.7%
Antiretroviral Therapy 4.3%
Product Used For Unknown Indication 3.6%
Acquired Immunodeficiency Syndrome 2.8%
Hiv Test Positive 1.4%
Antifungal Prophylaxis 1.1%
Hepatitis C 1.0%
Insomnia 0.9%
Prophylaxis 0.9%
Human Immunodeficiency Virus Transmission 0.8%
Hypertension 0.8%
Factor Viii Deficiency 0.7%
Maternal Exposure During Pregnancy 0.7%
Antiviral Prophylaxis 0.6%
Systemic Antiviral Treatment 0.6%
Gastric Ulcer 0.6%
Prophylaxis Against Hiv Infection 0.5%
Progressive External Ophthalmoplegia 23.1%
Osteoporosis 7.4%
Vomiting 7.4%
Spinal Fracture 5.4%
Drug Resistance 5.0%
Hepatotoxicity 5.0%
Portal Hypertension 4.1%
Viral Mutation Identified 4.1%
Drug Exposure During Pregnancy 3.7%
Virologic Failure 3.7%
Osteonecrosis 3.3%
Premature Baby 3.3%
Pulmonary Hypertension 3.3%
Renal Failure Acute 3.3%
Transient Ischaemic Attack 3.3%
Pruritus 2.9%
Spinal Compression Fracture 2.9%
Varices Oesophageal 2.9%
Visual Impairment 2.9%
White Blood Cell Count Decreased 2.9%
Concomitant
Hiv Infection 75.4%
Burkitt's Lymphoma 5.3%
Drug Use For Unknown Indication 3.4%
Hepatitis C 1.8%
Maternal Exposure Timing Unspecified 1.8%
Acquired Immunodeficiency Syndrome 1.3%
Antiretroviral Therapy 1.2%
Convulsion 1.2%
Factor Viii Deficiency 1.1%
Insomnia 1.0%
Product Used For Unknown Indication 0.8%
Cytomegalovirus Infection 0.8%
Diarrhoea 0.8%
Mycobacterium Avium Complex Infection 0.8%
Diarrhoea Infectious 0.7%
Systemic Antiviral Treatment 0.7%
Antiviral Prophylaxis 0.6%
Asthma 0.6%
Adrenal Insufficiency 0.5%
Haemorrhage 0.5%
Death 12.8%
Weight Decreased 9.3%
Rash Papular 7.0%
Visual Disturbance 7.0%
Abortion Induced 5.8%
Sick Sinus Syndrome 5.8%
Pneumonia 4.7%
Renal Tubular Disorder 4.7%
Retinal Detachment 4.7%
Spinal Fracture 4.7%
Drug Resistance 3.5%
Hepatitis 3.5%
Pain In Extremity 3.5%
Premature Rupture Of Membranes 3.5%
Psychotic Disorder 3.5%
Spinal Compression Fracture 3.5%
Stomach Mass 3.5%
Suicide Attempt 3.5%
Thoracic Vertebral Fracture 3.5%
Blood Triglycerides Increased 2.3%
Interacting
Antiretroviral Therapy 37.9%
Hiv Infection 31.0%
Drug Use For Unknown Indication 10.3%
Chronic Obstructive Pulmonary Disease 4.6%
Fungal Infection 4.6%
Lung Neoplasm Malignant 3.4%
Pulmonary Hypertension 2.3%
Antiviral Treatment 1.1%
Immunosuppression 1.1%
Organic Erectile Dysfunction 1.1%
Product Used For Unknown Indication 1.1%
Renal Transplant 1.1%
Drug Level Increased 23.5%
Drug Interaction 17.6%
Neuropathy Peripheral 11.8%
Thrombocytopenia 11.8%
Drug Metabolising Enzyme Test Abnormal 5.9%
Herpes Simplex 5.9%
Muscular Weakness 5.9%
Overdose 5.9%
Pain In Extremity 5.9%
Transaminases Increased 5.9%