Lamivudine combined with Saquinavir

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Abortion Induced Other Serious 5/1/2001 28 Female 1/5/2006 Japan
Primary
Concomitant
Pregnancy Other Serious 1/1/2002 28 Female 1/18/2006 Physician Spain
Primary
Secondary
Pre-eclampsia Other Serious 1/1/2002 42 Female 1/18/2006 Physician Spain
Primary
Secondary
Small For Dates Baby Other Serious 1/1/2002 2 lb 1/18/2006 Physician Spain
Primary
Secondary
Hepatic Function Abnormal Hospitalization 5/31/1999 52 Male 1/18/2006 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 7/9/2004 Male 1/23/2006 Japan
Primary
Secondary
Concomitant
Libido Decreased Male 1/27/2006 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/8/2001 Male 1/27/2006 Japan
Primary
Secondary
Concomitant
Sensory Disturbance Other Serious 34 Male 1/30/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Atypical Mycobacterial Infection Hospitalization 3/26/2004 Male 2/15/2006 Brazil
Primary
Concomitant
Pre-eclampsia Other Serious 1/1/2002 42 Female 2/28/2006
Primary
Secondary
Concomitant
Pre-eclampsia Other Serious 1/1/2002 28 Female 2/28/2006
Primary
Secondary
Therapeutic Agent Toxicity Other Serious 2/1/1999 41 Male 3/6/2006 Physician Germany
Primary
Secondary
Concomitant
Diabetic Ketoacidosis Hospitalization 48 Female 3/9/2006 Denmark
Primary
Secondary
Pancytopenia Other Serious 10/1/1999 Male 3/13/2006 Physician Japan
Primary
Secondary
Concomitant
Umbilical Hernia Other Serious 12/1/1998 40 Male 209 lb 3/22/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Toxoplasmosis Disability 37 Male 143 lb 3/22/2006 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/1999 52 Male 172 lb 3/22/2006 Physician Germany
Primary
Secondary
Concomitant
Tremor Other Serious 8/22/1994 61 Male 176 lb 3/22/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/1999 24 Male 209 lb 3/22/2006 Physician Germany
Primary
Secondary
Concomitant
Polyneuropathy Other Serious 1/1/1997 49 Male 150 lb 3/23/2006 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Other Serious 4/1/2002 Male 139 lb 3/27/2006 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/1998 42 Male 143 lb 3/27/2006 Physician Germany
Primary
Secondary
Concomitant
Weight Gain Poor Other Serious 1/1/2001 Male 181 lb 3/27/2006 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Other Serious 58 Male 106 lb 3/28/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Reflux Oesophagitis Other Serious 6/1/1998 40 Male 181 lb 3/28/2006 Physician Germany
Primary
Secondary
Concomitant
Toxoplasmosis Disability 37 Male 3/29/2006 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Other Serious 4/1/2002 Male 3/29/2006 Physician Germany
Primary
Secondary
Concomitant
Syncope Other Serious 1/6/2004 Male 4/17/2006 Other Health Professional Germany
Primary
Secondary
Pyrexia Other Serious 1/1/1998 Male 154 lb 4/17/2006 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Other Serious 56 Male 5/3/2006 Physician Canada
Primary
Secondary
Concomitant
Premature Rupture Of Membranes Hospitalization 11/20/2003 Female 5/4/2006 Physician Japan
Primary
Concomitant
Weight Decreased Other Serious 4/1/1998 Male 139 lb 5/8/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Tuberculosis Other Serious 1/1/2001 Male 176 lb 5/8/2006 Physician Germany
Primary
Secondary
Concomitant
Oral Candidiasis Other Serious 1/1/2001 Male 198 lb 5/8/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Viral Load Increased Other Serious 4/1/1999 Male 110 lb 5/8/2006 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/1/1998 Male 139 lb 5/18/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Drug Ineffective Death 11/6/2004 45 Male 5/19/2006 United States
Primary
Concomitant
Death Death 11/6/2004 45 Male 5/19/2006 United States
Primary
Concomitant
Staphylococcal Infection Other Serious 7/9/2004 Male 5/26/2006 Physician Japan
Primary
Secondary
Concomitant
Lipoatrophy Hospitalization 10/17/2002 Female 6/8/2006 Physician Japan
Primary
Secondary
Concomitant
Varices Oesophageal Other Serious 1/1/2003 65 Male 6/9/2006 Physician France
Primary
Concomitant
Renal Failure Acute Other Serious 6/12/2003 49 Male 164 lb 6/13/2006 Canada
Primary
Secondary
Concomitant
Viral Mutation Identified Death 11/1/2001 39 Male 6/20/2006
Primary
Secondary
Drug Ineffective Death 11/6/2004 45 Male 6/30/2006 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/1998 Male 7/7/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/1998 Male 7/19/2006 Physician Japan
Primary
Secondary
Concomitant
Oral Discomfort Other Serious 1/1/2005 42 Female 7/20/2006 Other Health Professional Spain
Primary
Secondary
Overdose Other Serious 12/1/1997 36 Male 7/18/2006 Spain
Primary
Secondary
Concomitant
Oral Discomfort Other Serious 1/1/2005 42 Female 7/31/2006 Other Health Professional Spain
Primary
Secondary
Small Cell Lung Cancer Stage Unspecified Death 34 Male 8/3/2006 Poland
Primary
Secondary
Pancreatitis Acute Hospitalization 8/21/2002 Male 117 lb 8/11/2006 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 7/1/2005 Male 8/14/2006 Physician United States
Primary
Secondary
Concomitant
Urinary Sediment Abnormal Hospitalization 7/27/2000 Male 8/18/2006 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 7/9/2004 Male 8/21/2006 Physician Japan
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 8/21/2002 Male 117 lb 8/22/2006 Physician Japan
Primary
Secondary
Concomitant
Lipoatrophy Hospitalization 10/17/2002 Female 8/23/2006 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2006 39 Male 8/30/2006 Physician Thailand
Primary
Concomitant
Transaminases Increased Other Serious 7/1/2006 40 Male 9/1/2006 Physician Brazil
Primary
Concomitant
Heart Rate Irregular Other Serious 8/28/2006 53 Male 165 lb 8/30/2006 Consumer Mexico
Primary
Concomitant
Urinary Sediment Abnormal Hospitalization 7/27/2000 Male 9/8/2006 Physician Japan
Primary
Secondary
Concomitant
Sick Sinus Syndrome Other Serious 10/1/1999 Male 9/8/2006 Physician Japan
Primary
Secondary
Concomitant
Rib Fracture Other Serious 1/1/1996 Male 9/13/2006
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/1/2004 46 Male 9/20/2006 Physician Germany
Primary
Secondary
Pneumonitis Other Serious 9/1/1997 46 Male 10/3/2006
Primary
Secondary
Hepatic Neoplasm Malignant Hospitalization 2/22/2006 Male 10/5/2006 Physician Japan
Primary
Concomitant
Hiv Infection Death Male 10/6/2006 Argentina
Primary
Concomitant
Death Death 6/30/2005 Male 10/12/2006 United States
Primary
Concomitant
Osteonecrosis Hospitalization 8/1/1996 47 Male 10/18/2006 Physician Japan
Primary
Secondary
Concomitant
Electrocardiogram Qt Corrected Interval Prolonged Hospitalization 8/9/2006 45 Male 177 lb 10/23/2006 Pharmacist United States
Primary
Secondary
Concomitant
Bladder Cancer Other Serious 1/1/2000 58 Male 10/26/2006 Other Health Professional Italy
Primary
Secondary
Gait Disturbance Other Serious 36 Male 10/27/2006 Canada
Primary
Secondary
Concomitant
Interacting
Hyponatraemia Other Serious 49 Female 10/27/2006 Canada
Primary
Secondary
Concomitant
Interacting
Vertigo Other Serious 36 Male 10/27/2006 Canada
Primary
Secondary
Concomitant
Interacting
Alpha 1 Foetoprotein Abnormal Other Serious 11/1/2006 Consumer United Kingdom
Primary
Secondary
Drug Exposure During Pregnancy Congenital Anomaly 4/11/2006 11/21/2006 Consumer United Kingdom
Primary
Secondary
Treatment Noncompliance Hospitalization 3/26/2004 Male 11/30/2006 Brazil
Primary
Concomitant
Nuclear Magnetic Resonance Imaging Abnormal Hospitalization 8/8/2000 2 Female 12/4/2006 Consumer France
Primary
Secondary
Tachypnoea Hospitalization 36 Male 12/12/2006
Primary
Secondary
Splenic Rupture Hospitalization 41 Male 12/15/2006
Primary
Secondary
Sick Sinus Syndrome Other Serious 10/1/1999 Male 12/29/2006 Physician Japan
Primary
Secondary
Concomitant
Syncope Hospitalization 41 Male 12/29/2006
Primary
Secondary
Splenic Rupture Other Serious 41 Male 1/4/2007 Germany
Primary
Secondary
Rhinitis Other Serious 1/22/1998 Female 1/8/2007 Consumer France
Primary
Secondary
Splenic Rupture Other Serious 41 Male 1/8/2007 Germany
Primary
Secondary
Small Cell Lung Cancer Stage Unspecified Death 34 Male 110 lb 1/17/2007 Poland
Primary
Secondary
Weight Decreased Other Serious 12/28/1999 Male 1/25/2007 Physician Japan
Primary
Secondary
Concomitant
Nephropathy Toxic Other Serious 51 Female 108 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Hypokalaemia Other Serious 40 Male 134 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Blood Triglycerides Increased Life Threatening 4/2/1998 49 Male 3/20/2007 Other Health Professional United States
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 3/21/2007 Consumer United Kingdom
Primary
Secondary
Visual Disturbance Life Threatening 3/16/1998 Male 3/24/2007 Physician Japan
Primary
Secondary
Concomitant
Visual Disturbance Life Threatening 3/16/1998 Male 4/27/2007 Physician Japan
Primary
Secondary
Concomitant
Hiv Infection Other Serious 5/9/2007
Primary
Secondary
Visual Disturbance Life Threatening 3/16/1998 Male 5/17/2007 Physician Japan
Primary
Secondary
Concomitant
Nuclear Magnetic Resonance Imaging Abnormal Hospitalization 8/8/2000 Female 6/1/2007 Other Health Professional United States
Primary
Secondary
Nuclear Magnetic Resonance Imaging Abnormal Hospitalization 8/8/2000 2 Female 6/5/2007 Consumer France
Primary
Secondary
Visual Disturbance Life Threatening 3/16/1998 Male 6/7/2007 Physician Japan
Primary
Secondary
Concomitant
Visual Disturbance Life Threatening 3/16/1998 Male 6/15/2007 Physician Japan
Primary
Secondary
Concomitant
Nuclear Magnetic Resonance Imaging Abnormal Hospitalization 8/8/2000 Female 6/15/2007 Other Health Professional United States
Primary
Secondary
Weight Decreased Other Serious 12/28/1999 Male 6/15/2007 Physician Japan
Primary
Secondary
Concomitant
Encephalitis Other Serious 8/1/2005 47 Male 6/19/2007 Physician France
Primary
Secondary
Concomitant
Lymphoma Other Serious 6/16/1998 Male 6/19/2007 Physician Japan
Primary
Secondary
Concomitant
Urticaria Chronic Hospitalization 10/17/2002 Female 7/13/2007 Physician Japan
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 7/30/2007 Other Health Professional Italy
Primary
Secondary
Hepatotoxicity Other Serious 40 Male 8/1/2007 Physician Spain
Primary
Secondary
Melaena Hospitalization 2/22/2006 Male 8/2/2007 Physician Japan
Primary
Concomitant
Sick Sinus Syndrome Other Serious 10/1/1999 Male 8/9/2007 Physician Japan
Primary
Secondary
Concomitant
Visceral Leishmaniasis Other Serious 1/1/2001 36 Female 8/10/2007 Italy
Primary
Concomitant
Visceral Leishmaniasis Other Serious 1/1/2001 36 Female 8/10/2007 Italy
Primary
Concomitant
Urinary Sediment Abnormal Hospitalization 7/27/2000 Male 8/23/2007 Physician Japan
Primary
Secondary
Concomitant
Hepatosplenomegaly Congenital Anomaly 6/1/2002 0 Male 6 lb 8/31/2007 United States
Primary
Secondary
Stillbirth Other Serious 2/1/2005 36 Female 8/31/2007 United States
Primary
Secondary
Concomitant
Premature Baby Congenital Anomaly 12/1/2001 0 Male 8/31/2007 United States
Primary
Secondary
Premature Baby Congenital Anomaly 3/1/2003 0 Female 8/31/2007 United States
Primary
Secondary
Premature Baby Congenital Anomaly 3/1/2003 0 Female 8/31/2007 United States
Primary
Secondary
Stillbirth Other Serious 2/1/2005 36 Female 8/31/2007 United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 8/21/2002 Male 117 lb 9/5/2007 Physician Japan
Primary
Secondary
Concomitant
Melaena Life Threatening 2/22/2006 Male 9/7/2007 Physician Japan
Primary
Concomitant
Drug Resistance Other Serious Male 9/10/2007 Czech Republic
Primary
Secondary
Drug Resistance Other Serious Male 9/10/2007 Czech Republic
Primary
Concomitant
Drug Resistance Other Serious Male 9/10/2007 Czech Republic
Primary
Secondary
Concomitant
Drug Resistance Other Serious Female 9/10/2007 Czech Republic
Primary
Secondary
Drug Resistance Other Serious Male 9/10/2007 Czech Republic
Primary
Secondary
Drug Resistance Other Serious Male 9/10/2007 Czech Republic
Primary
Secondary
Drug Resistance Other Serious Male 9/10/2007 Czech Republic
Primary
Secondary
Drug Resistance Other Serious Male 9/10/2007 Czech Republic
Primary
Secondary
Drug Resistance Other Serious Male 9/10/2007 Czech Republic
Primary
Secondary
Pregnancy Congenital Anomaly Female 2 lb 9/13/2007 Other Health Professional United States
Primary
Secondary
Pregnancy Congenital Anomaly Female 2 lb 9/17/2007 Other Health Professional United States
Primary
Secondary
Unevaluable Event Other Serious Male 5 lb 9/21/2007 United States
Primary
Secondary
Concomitant
Urticaria Chronic Hospitalization 10/17/2002 Female 10/4/2007 Physician Japan
Primary
Secondary
Concomitant
Visual Disturbance Other Serious 1/1/2002 Male 10/5/2007 Other Health Professional France
Primary
Secondary
Concomitant
Hepatosplenomegaly Congenital Anomaly 6/1/2002 0 Male 6 lb 10/12/2007 United States
Primary
Secondary
Pain Other Serious 9/1/2007 Male 11/1/2007 Chile
Primary
Concomitant
Pain Other Serious 9/1/2007 Male 11/12/2007 Chile
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/1999 40 Male 11/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 8/21/2002 Male 117 lb 11/20/2007 Physician Japan
Primary
Secondary
Concomitant
Drug Exposure During Pregnancy Congenital Anomaly 11/27/2007 Physician Spain
Primary
Concomitant
Viral Mutation Identified Other Serious 4/1/2002 Male 12/11/2007
Primary
Secondary
Pneumonia Hospitalization 1/24/2008 Male 2/6/2008 Chile
Primary
Concomitant
Homicide Death 6/30/2005 Male 2/6/2008 United States
Primary
Concomitant
Hiv Infection Other Serious 2/8/2008
Primary
Secondary
Death Death 6/30/2005 Male 2/12/2008 United States
Primary
Concomitant
Pneumonia Hospitalization 1/24/2008 Male 143 lb 2/18/2008 Chile
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 5/31/1999 52 Male 2/27/2008 Physician United States
Primary
Secondary
Concomitant
Gun Shot Wound Death 6/30/2005 Male 2/27/2008 United States
Primary
Concomitant
Pneumonia Hospitalization 9/1/2007 Male 3/11/2008 Physician
Primary
Concomitant
Drug Resistance Other Serious 42 Male 3/13/2008 Spain
Primary
Concomitant
Drug Resistance Other Serious 42 Male 3/14/2008 Spain
Primary
Concomitant

Drug Data